# Only cancer types with minimum 2000 mutations for SBS signatures with average probability at least 0.75 are considered. signature cancer_type processive_group_length number_of_processive_groups log10_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_number_of_processive_groups SBS9 Lymph-BNHL 2 1609 3.207 0.48 681.0 793.0 742.35 24.385 1.6325536852924865e-271 3.265107370584973e-270 269.486 [758, 760, 772, 718, 721, 732, 748, 712, 738, 711, 771, 748, 750, 770, 752, 752, 760, 781, 759, 715, 681, 769, 743, 769, 759, 737, 781, 744, 758, 758, 760, 721, 726, 769, 751, 706, 763, 734, 719, 758, 793, 719, 711, 760, 688, 766, 712, 706, 771, 735, 752, 712, 755, 697, 770, 738, 717, 726, 762, 788, 738, 730, 751, 733, 748, 749, 701, 747, 741, 704, 740, 768, 741, 758, 764, 792, 724, 765, 763, 740, 768, 690, 743, 750, 727, 750, 733, 728, 745, 732, 719, 781, 746, 681, 764, 726, 745, 723, 740, 735] SBS9 Lymph-BNHL 3 55 1.74 0.261 3.0 13.0 7.29 2.246 1.8200892213426894e-98 7.280356885370758e-98 97.138 [7, 5, 3, 10, 8, 12, 7, 8, 6, 7, 6, 3, 11, 10, 7, 9, 13, 7, 6, 5, 6, 5, 4, 7, 3, 10, 5, 10, 8, 5, 8, 11, 11, 9, 8, 5, 5, 5, 10, 6, 7, 5, 8, 6, 4, 12, 7, 9, 8, 9, 9, 9, 8, 10, 7, 7, 11, 7, 8, 10, 10, 7, 7, 4, 8, 8, 10, 8, 5, 11, 5, 5, 5, 7, 6, 9, 7, 6, 6, 8, 11, 8, 9, 8, 8, 4, 4, 7, 4, 8, 7, 6, 6, 4, 8, 7, 4, 9, 9, 4] SBS9 Lymph-BNHL 4 3 0.477 0.071 1.0 1.0 1.0 0.0 1.8200892213426894e-98 7.280356885370758e-98 97.138 [1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1] SBS9 Lymph-BNHL 5 3 0.477 0.071 inf [] SBS9 Lymph-BNHL 6 1 0.0 0.0 inf [] SBS9 Lymph-CLL 2 62 1.792 0.48 21.0 52.0 33.24 5.627 2.0932921569536195e-07 1.4653045098675336e-06 5.834 [30, 39, 39, 39, 24, 35, 26, 32, 35, 38, 52, 26, 35, 31, 33, 38, 26, 29, 26, 31, 41, 33, 31, 35, 30, 28, 38, 29, 28, 25, 31, 39, 40, 30, 31, 26, 45, 32, 34, 29, 31, 33, 42, 38, 25, 37, 32, 31, 35, 28, 24, 38, 30, 32, 36, 21, 32, 29, 38, 44, 24, 43, 31, 33, 43, 32, 32, 44, 32, 26, 31, 35, 33, 27, 35, 32, 41, 40, 29, 30, 27, 32, 33, 36, 42, 30, 31, 24, 41, 35, 27, 31, 38, 29, 35, 37, 37, 38, 40, 33] SBS9 Lymph-CLL 3 1 0.0 0.0 1.0 2.0 1.25 0.433 0.6726395769907115 0.8345366488286836 0.079 [1, 1, 1, 2] SBS9 Skin-Melanoma 2 87 1.94 0.48 17.0 43.0 28.94 4.485 6.65436345636535e-38 8.74200689365644e-38 37.058 [29, 28, 25, 25, 29, 22, 35, 29, 32, 36, 33, 17, 31, 28, 23, 21, 31, 25, 24, 37, 28, 34, 28, 38, 26, 30, 29, 32, 25, 30, 34, 27, 28, 31, 32, 29, 31, 30, 33, 29, 26, 28, 26, 29, 28, 27, 27, 27, 26, 28, 31, 26, 37, 25, 30, 31, 34, 27, 21, 25, 23, 35, 28, 27, 27, 23, 34, 28, 38, 30, 26, 33, 30, 27, 34, 43, 25, 22, 33, 31, 19, 28, 32, 20, 34, 26, 28, 31, 32, 36, 23, 26, 34, 30, 29, 24, 31, 35, 25, 31] SBS9 Skin-Melanoma 3 4 0.602 0.149 1.0 2.0 1.333 0.471 2.1001969880109998e-07 2.3067737409301142e-07 6.637 [1, 2, 1, 1, 1, 1, 2, 2, 1] SBS9 Skin-Melanoma 4 2 0.301 0.075 1.0 1.0 1.0 0.0 inf [1] signature cancer_type processive_group_length avg_number_of_processive_groups log10_avg_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_avg_number_of_processive_groups SBS9 ACROSS_ALL_CANCER_TYPES 2 586.0 2.768 0.48 246.667 289.0 268.177 8.614 1.8863258580362163e-292 2.8294887870543247e-292 291.548 [272.333, 275.667, 278.667, 260.667, 258.0, 263.0, 269.667, 257.667, 268.333, 261.667, 285.333, 263.667, 272.0, 276.333, 269.333, 270.333, 272.333, 278.333, 269.667, 261.0, 250.0, 278.667, 267.333, 280.667, 271.667, 265.0, 282.667, 268.333, 270.333, 271.0, 275.0, 262.333, 264.667, 276.667, 271.333, 253.667, 279.667, 265.333, 262.0, 272.0, 283.333, 260.0, 259.667, 275.667, 247.0, 276.667, 257.0, 254.667, 277.333, 263.667, 269.0, 258.667, 274.0, 251.333, 278.667, 263.333, 261.0, 260.667, 273.667, 285.667, 261.667, 269.333, 270.0, 264.333, 272.667, 268.0, 255.667, 273.0, 270.333, 253.333, 265.667, 278.667, 268.0, 270.667, 277.667, 289.0, 263.333, 275.667, 275.0, 267.0, 271.333, 250.0, 269.333, 268.667, 267.667, 268.667, 264.0, 261.0, 272.667, 267.667, 256.333, 279.333, 272.667, 246.667, 276.0, 262.333, 271.0, 265.333, 268.333, 266.333] SBS9 ACROSS_ALL_CANCER_TYPES 3 20.0 1.301 0.226 1.667 5.194 3.291 0.753 2.8999073750619746e-107 2.8999073750619746e-107 106.538 [3.0, 2.667, 1.667, 4.333, 3.417, 4.75, 3.417, 3.75, 2.75, 3.194, 2.861, 1.861, 4.528, 4.194, 3.194, 3.861, 5.194, 3.194, 2.861, 2.528, 2.861, 2.528, 2.194, 3.194, 1.861, 4.194, 2.528, 4.194, 3.528, 2.528, 3.528, 4.528, 4.528, 3.861, 3.528, 2.528, 2.528, 2.528, 4.194, 2.861, 3.194, 2.528, 3.528, 2.861, 2.194, 4.861, 3.194, 3.861, 3.528, 3.861, 3.861, 3.861, 3.528, 4.194, 3.194, 3.194, 4.528, 3.194, 3.528, 4.194, 4.194, 3.194, 3.194, 2.194, 3.528, 3.528, 4.194, 3.528, 2.528, 4.528, 2.528, 2.528, 2.528, 3.194, 2.861, 3.861, 3.194, 2.861, 2.861, 3.528, 4.528, 3.528, 3.861, 3.528, 3.528, 2.194, 2.194, 3.194, 2.194, 3.528, 3.194, 2.861, 2.861, 2.194, 3.528, 3.194, 2.194, 3.861, 3.861, 2.194] SBS9 ACROSS_ALL_CANCER_TYPES 4 2.5 0.398 0.069 1.0 1.0 1.0 0.0 0.0 0.0 inf [1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0] SBS9 ACROSS_ALL_CANCER_TYPES 5 3.0 0.477 0.083 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS9 ACROSS_ALL_CANCER_TYPES 6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]