# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. # For real mutations on genic (transcribed:T, untranscribed:U and bitranscribed:B) and intergenic (nontranscribed:N) regions averaged across cancer types. MutationType Across_All_Cancer_Types T:A[C>A]A 5.0 U:A[C>A]A 3.2 B:A[C>A]A 0.0 N:A[C>A]A 36.8 T:A[C>A]C 41.8 U:A[C>A]C 32.2 B:A[C>A]C 0.0 N:A[C>A]C 210.0 T:A[C>A]G 1.2 U:A[C>A]G 0.0 B:A[C>A]G 0.0 N:A[C>A]G 8.4 T:A[C>A]T 25.8 U:A[C>A]T 23.0 B:A[C>A]T 0.0 N:A[C>A]T 168.0 T:A[C>G]A 40.0 U:A[C>G]A 30.6 B:A[C>G]A 0.0 N:A[C>G]A 200.2 T:A[C>G]C 12.8 U:A[C>G]C 8.4 B:A[C>G]C 0.0 N:A[C>G]C 60.8 T:A[C>G]G 3.0 U:A[C>G]G 2.4 B:A[C>G]G 0.0 N:A[C>G]G 23.4 T:A[C>G]T 40.8 U:A[C>G]T 40.8 B:A[C>G]T 0.0 N:A[C>G]T 215.8 T:A[C>T]A 96.0 U:A[C>T]A 70.2 B:A[C>T]A 0.0 N:A[C>T]A 362.4 T:A[C>T]C 49.4 U:A[C>T]C 43.8 B:A[C>T]C 0.0 N:A[C>T]C 200.8 T:A[C>T]G 42.2 U:A[C>T]G 34.0 B:A[C>T]G 0.0 N:A[C>T]G 166.6 T:A[C>T]T 60.8 U:A[C>T]T 51.0 B:A[C>T]T 0.2 N:A[C>T]T 262.8 T:A[T>A]A 182.6 U:A[T>A]A 163.6 B:A[T>A]A 0.6 N:A[T>A]A 788.8 T:A[T>A]C 40.2 U:A[T>A]C 29.4 B:A[T>A]C 0.0 N:A[T>A]C 170.4 T:A[T>A]G 26.2 U:A[T>A]G 24.2 B:A[T>A]G 0.0 N:A[T>A]G 157.4 T:A[T>A]T 237.8 U:A[T>A]T 237.4 B:A[T>A]T 0.6 N:A[T>A]T 1173.4 T:A[T>C]A 209.4 U:A[T>C]A 178.8 B:A[T>C]A 0.2 N:A[T>C]A 781.6 T:A[T>C]C 110.2 U:A[T>C]C 87.2 B:A[T>C]C 0.2 N:A[T>C]C 444.4 T:A[T>C]G 108.0 U:A[T>C]G 92.2 B:A[T>C]G 0.2 N:A[T>C]G 433.2 T:A[T>C]T 236.2 U:A[T>C]T 241.2 B:A[T>C]T 0.4 N:A[T>C]T 971.8 T:A[T>G]A 339.4 U:A[T>G]A 341.6 B:A[T>G]A 1.0 N:A[T>G]A 1931.8 T:A[T>G]C 48.0 U:A[T>G]C 47.6 B:A[T>G]C 0.0 N:A[T>G]C 281.0 T:A[T>G]G 30.4 U:A[T>G]G 31.8 B:A[T>G]G 0.0 N:A[T>G]G 194.4 T:A[T>G]T 194.6 U:A[T>G]T 228.4 B:A[T>G]T 0.0 N:A[T>G]T 1053.2 T:C[C>A]A 53.6 U:C[C>A]A 47.4 B:C[C>A]A 0.0 N:C[C>A]A 293.0 T:C[C>A]C 16.2 U:C[C>A]C 10.8 B:C[C>A]C 0.0 N:C[C>A]C 88.8 T:C[C>A]G 4.0 U:C[C>A]G 5.0 B:C[C>A]G 0.0 N:C[C>A]G 22.8 T:C[C>A]T 35.4 U:C[C>A]T 36.6 B:C[C>A]T 0.2 N:C[C>A]T 236.2 T:C[C>G]A 3.2 U:C[C>G]A 3.6 B:C[C>G]A 0.0 N:C[C>G]A 21.6 T:C[C>G]C 5.2 U:C[C>G]C 3.6 B:C[C>G]C 0.0 N:C[C>G]C 24.6 T:C[C>G]G 0.2 U:C[C>G]G 0.8 B:C[C>G]G 0.0 N:C[C>G]G 2.4 T:C[C>G]T 13.2 U:C[C>G]T 18.0 B:C[C>G]T 0.0 N:C[C>G]T 74.4 T:C[C>T]A 91.2 U:C[C>T]A 86.4 B:C[C>T]A 0.2 N:C[C>T]A 358.8 T:C[C>T]C 97.4 U:C[C>T]C 89.8 B:C[C>T]C 0.0 N:C[C>T]C 352.0 T:C[C>T]G 56.8 U:C[C>T]G 63.0 B:C[C>T]G 0.0 N:C[C>T]G 207.2 T:C[C>T]T 120.4 U:C[C>T]T 120.2 B:C[C>T]T 0.0 N:C[C>T]T 486.6 T:C[T>A]A 64.0 U:C[T>A]A 60.2 B:C[T>A]A 0.0 N:C[T>A]A 305.2 T:C[T>A]C 22.0 U:C[T>A]C 19.2 B:C[T>A]C 0.0 N:C[T>A]C 119.8 T:C[T>A]G 46.4 U:C[T>A]G 46.6 B:C[T>A]G 0.2 N:C[T>A]G 258.6 T:C[T>A]T 45.6 U:C[T>A]T 49.8 B:C[T>A]T 0.0 N:C[T>A]T 289.0 T:C[T>C]A 136.0 U:C[T>C]A 123.8 B:C[T>C]A 0.2 N:C[T>C]A 555.6 T:C[T>C]C 151.8 U:C[T>C]C 149.4 B:C[T>C]C 0.2 N:C[T>C]C 663.2 T:C[T>C]G 122.6 U:C[T>C]G 126.8 B:C[T>C]G 0.4 N:C[T>C]G 527.0 T:C[T>C]T 292.4 U:C[T>C]T 312.2 B:C[T>C]T 1.0 N:C[T>C]T 1407.2 T:C[T>G]A 225.2 U:C[T>G]A 202.4 B:C[T>G]A 0.2 N:C[T>G]A 1152.0 T:C[T>G]C 57.0 U:C[T>G]C 55.4 B:C[T>G]C 0.2 N:C[T>G]C 289.6 T:C[T>G]G 129.6 U:C[T>G]G 128.0 B:C[T>G]G 0.4 N:C[T>G]G 616.4 T:C[T>G]T 561.4 U:C[T>G]T 601.8 B:C[T>G]T 1.8 N:C[T>G]T 2909.4 T:G[C>A]A 73.8 U:G[C>A]A 70.2 B:G[C>A]A 0.0 N:G[C>A]A 379.4 T:G[C>A]C 44.2 U:G[C>A]C 43.0 B:G[C>A]C 0.0 N:G[C>A]C 240.8 T:G[C>A]G 0.0 U:G[C>A]G 0.0 B:G[C>A]G 0.0 N:G[C>A]G 1.0 T:G[C>A]T 65.8 U:G[C>A]T 67.8 B:G[C>A]T 0.0 N:G[C>A]T 379.4 T:G[C>G]A 5.6 U:G[C>G]A 5.6 B:G[C>G]A 0.0 N:G[C>G]A 40.2 T:G[C>G]C 13.4 U:G[C>G]C 17.4 B:G[C>G]C 0.0 N:G[C>G]C 89.4 T:G[C>G]G 0.8 U:G[C>G]G 0.6 B:G[C>G]G 0.0 N:G[C>G]G 2.4 T:G[C>G]T 35.4 U:G[C>G]T 46.0 B:G[C>G]T 0.2 N:G[C>G]T 182.0 T:G[C>T]A 74.8 U:G[C>T]A 71.4 B:G[C>T]A 0.2 N:G[C>T]A 302.0 T:G[C>T]C 73.4 U:G[C>T]C 74.4 B:G[C>T]C 0.0 N:G[C>T]C 272.8 T:G[C>T]G 53.8 U:G[C>T]G 53.8 B:G[C>T]G 0.0 N:G[C>T]G 196.4 T:G[C>T]T 140.0 U:G[C>T]T 131.4 B:G[C>T]T 0.4 N:G[C>T]T 488.6 T:G[T>A]A 32.4 U:G[T>A]A 39.0 B:G[T>A]A 0.0 N:G[T>A]A 164.6 T:G[T>A]C 41.8 U:G[T>A]C 36.6 B:G[T>A]C 0.0 N:G[T>A]C 138.4 T:G[T>A]G 4.8 U:G[T>A]G 6.8 B:G[T>A]G 0.0 N:G[T>A]G 35.0 T:G[T>A]T 23.6 U:G[T>A]T 25.0 B:G[T>A]T 0.0 N:G[T>A]T 155.8 T:G[T>C]A 116.0 U:G[T>C]A 122.6 B:G[T>C]A 0.8 N:G[T>C]A 493.0 T:G[T>C]C 151.4 U:G[T>C]C 153.6 B:G[T>C]C 0.6 N:G[T>C]C 555.2 T:G[T>C]G 70.0 U:G[T>C]G 74.8 B:G[T>C]G 0.0 N:G[T>C]G 289.2 T:G[T>C]T 126.8 U:G[T>C]T 162.2 B:G[T>C]T 0.2 N:G[T>C]T 587.4 T:G[T>G]A 78.0 U:G[T>G]A 93.6 B:G[T>G]A 0.4 N:G[T>G]A 337.2 T:G[T>G]C 49.6 U:G[T>G]C 58.6 B:G[T>G]C 0.0 N:G[T>G]C 263.2 T:G[T>G]G 38.4 U:G[T>G]G 46.0 B:G[T>G]G 0.0 N:G[T>G]G 195.4 T:G[T>G]T 241.2 U:G[T>G]T 324.4 B:G[T>G]T 1.0 N:G[T>G]T 1240.0 T:T[C>A]A 159.8 U:T[C>A]A 157.8 B:T[C>A]A 0.4 N:T[C>A]A 892.4 T:T[C>A]C 12.6 U:T[C>A]C 12.4 B:T[C>A]C 0.0 N:T[C>A]C 99.0 T:T[C>A]G 1.0 U:T[C>A]G 1.0 B:T[C>A]G 0.0 N:T[C>A]G 8.0 T:T[C>A]T 253.6 U:T[C>A]T 273.4 B:T[C>A]T 0.8 N:T[C>A]T 1429.0 T:T[C>G]A 15.2 U:T[C>G]A 17.2 B:T[C>G]A 0.0 N:T[C>G]A 97.2 T:T[C>G]C 6.8 U:T[C>G]C 8.0 B:T[C>G]C 0.0 N:T[C>G]C 49.6 T:T[C>G]G 0.2 U:T[C>G]G 0.6 B:T[C>G]G 0.0 N:T[C>G]G 4.0 T:T[C>G]T 38.4 U:T[C>G]T 51.0 B:T[C>G]T 0.0 N:T[C>G]T 230.4 T:T[C>T]A 43.4 U:T[C>T]A 46.2 B:T[C>T]A 0.0 N:T[C>T]A 215.6 T:T[C>T]C 73.4 U:T[C>T]C 84.8 B:T[C>T]C 0.0 N:T[C>T]C 325.8 T:T[C>T]G 24.0 U:T[C>T]G 26.4 B:T[C>T]G 0.0 N:T[C>T]G 109.6 T:T[C>T]T 63.8 U:T[C>T]T 79.2 B:T[C>T]T 0.0 N:T[C>T]T 327.4 T:T[T>A]A 273.0 U:T[T>A]A 316.0 B:T[T>A]A 1.2 N:T[T>A]A 1296.2 T:T[T>A]C 11.4 U:T[T>A]C 10.0 B:T[T>A]C 0.0 N:T[T>A]C 71.6 T:T[T>A]G 98.2 U:T[T>A]G 127.6 B:T[T>A]G 0.0 N:T[T>A]G 695.4 T:T[T>A]T 152.8 U:T[T>A]T 190.0 B:T[T>A]T 0.2 N:T[T>A]T 822.6 T:T[T>C]A 149.2 U:T[T>C]A 156.8 B:T[T>C]A 0.2 N:T[T>C]A 656.0 T:T[T>C]C 199.2 U:T[T>C]C 214.0 B:T[T>C]C 0.6 N:T[T>C]C 816.8 T:T[T>C]G 75.0 U:T[T>C]G 92.4 B:T[T>C]G 0.0 N:T[T>C]G 402.8 T:T[T>C]T 387.0 U:T[T>C]T 480.6 B:T[T>C]T 2.8 N:T[T>C]T 1656.4 T:T[T>G]A 466.2 U:T[T>G]A 503.0 B:T[T>G]A 1.2 N:T[T>G]A 2860.8 T:T[T>G]C 50.6 U:T[T>G]C 55.2 B:T[T>G]C 0.2 N:T[T>G]C 298.4 T:T[T>G]G 79.6 U:T[T>G]G 102.0 B:T[T>G]G 0.2 N:T[T>G]G 499.8 T:T[T>G]T 542.6 U:T[T>G]T 698.2 B:T[T>G]T 1.6 N:T[T>G]T 2995.8 # There must be at least 1000 mutations on the strands. # Signature and mutation type must have at least 5% of all signature mutations on the strands. # Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1. cancer_type signature mutation_type genic_real_count intergenic_real_count genic_mean_sims_count intergenic_mean_sims_count genic_versus_intergenic_p_value genic_versus_intergenic_q_value percentage_of_mutations_on_strands signature_number_of_mutations_on_strands significant_strand FC_REAL FC_SIMS FC fold_change_1.1 fold_change_1.2 fold_change_1.3 fold_change_1.5 fold_change_1.75 fold_change_2+ Transcribed_real_count Transcribed_mean_sims_count Transcribed_min_sims_count Transcribed_max_sims_count Transcribed_sims_count_list UnTranscribed_real_count UnTranscribed_mean_sims_count UnTranscribed_min_sims_count UnTranscribed_max_sims_count UnTranscribed_sims_count_list NonTranscribed_real_count NonTranscribed_mean_sims_count NonTranscribed_min_sims_count NonTranscribed_max_sims_count NonTranscribed_sims_count_list Lymph-BNHL SBS9 C>A 2932.0 7374.0 4326.57 6007.81 6.312632968011133e-91 1.0760039995700423e-89 6.225 165551.0 Intergenic 2.515 1.389 1.811 1 1 1 1 1 1441.0 2153.27 2038.0 2252.0 [2159.0, 2204.0, 2155.0, 2154.0, 2126.0, 2198.0, 2123.0, 2174.0, 2151.0, 2198.0, 2124.0, 2220.0, 2100.0, 2134.0, 2137.0, 2162.0, 2114.0, 2115.0, 2147.0, 2159.0, 2096.0, 2144.0, 2172.0, 2202.0, 2216.0, 2129.0, 2132.0, 2120.0, 2113.0, 2120.0, 2197.0, 2189.0, 2150.0, 2164.0, 2200.0, 2200.0, 2123.0, 2127.0, 2152.0, 2202.0, 2094.0, 2155.0, 2138.0, 2171.0, 2148.0, 2103.0, 2128.0, 2125.0, 2252.0, 2179.0, 2119.0, 2038.0, 2121.0, 2098.0, 2117.0, 2188.0, 2139.0, 2137.0, 2218.0, 2185.0, 2078.0, 2195.0, 2159.0, 2167.0, 2166.0, 2094.0, 2187.0, 2222.0, 2136.0, 2248.0, 2099.0, 2124.0, 2164.0, 2142.0, 2178.0, 2225.0, 2164.0, 2176.0, 2176.0, 2172.0, 2189.0, 2098.0, 2069.0, 2137.0, 2121.0, 2114.0, 2136.0, 2212.0, 2118.0, 2144.0, 2161.0, 2145.0, 2191.0, 2092.0, 2219.0, 2216.0, 2210.0, 2158.0, 2103.0, 2167.0] 1491.0 2173.3 2091.0 2280.0 [2167.0, 2134.0, 2152.0, 2147.0, 2167.0, 2103.0, 2171.0, 2157.0, 2181.0, 2245.0, 2115.0, 2092.0, 2214.0, 2219.0, 2115.0, 2232.0, 2125.0, 2209.0, 2215.0, 2117.0, 2195.0, 2206.0, 2168.0, 2146.0, 2156.0, 2162.0, 2122.0, 2131.0, 2188.0, 2195.0, 2111.0, 2127.0, 2098.0, 2110.0, 2216.0, 2107.0, 2171.0, 2110.0, 2154.0, 2153.0, 2109.0, 2174.0, 2180.0, 2152.0, 2195.0, 2153.0, 2197.0, 2190.0, 2117.0, 2200.0, 2187.0, 2202.0, 2238.0, 2100.0, 2197.0, 2173.0, 2221.0, 2234.0, 2135.0, 2105.0, 2192.0, 2091.0, 2160.0, 2094.0, 2202.0, 2125.0, 2124.0, 2137.0, 2251.0, 2191.0, 2222.0, 2186.0, 2200.0, 2235.0, 2202.0, 2178.0, 2239.0, 2193.0, 2175.0, 2153.0, 2130.0, 2217.0, 2179.0, 2233.0, 2193.0, 2207.0, 2163.0, 2249.0, 2128.0, 2252.0, 2243.0, 2209.0, 2194.0, 2117.0, 2122.0, 2151.0, 2263.0, 2237.0, 2280.0, 2251.0] 7374.0 6007.81 5856.0 6133.0 [6008.0, 5997.0, 6030.0, 6026.0, 6041.0, 6043.0, 6037.0, 6001.0, 6000.0, 5897.0, 6101.0, 6023.0, 6029.0, 5978.0, 6088.0, 5945.0, 6089.0, 6012.0, 5976.0, 6069.0, 6047.0, 5980.0, 5992.0, 5974.0, 5965.0, 6049.0, 6079.0, 6082.0, 6036.0, 6026.0, 6028.0, 6008.0, 6102.0, 6055.0, 5926.0, 6034.0, 6036.0, 6091.0, 6023.0, 5987.0, 6118.0, 6014.0, 6020.0, 6017.0, 5992.0, 6070.0, 6018.0, 6029.0, 5958.0, 5954.0, 6029.0, 6093.0, 5989.0, 6133.0, 6009.0, 5968.0, 5975.0, 5970.0, 5980.0, 6047.0, 6067.0, 6045.0, 6014.0, 6067.0, 5970.0, 6111.0, 6020.0, 5968.0, 5955.0, 5893.0, 6018.0, 6028.0, 5974.0, 5964.0, 5955.0, 5925.0, 5926.0, 5959.0, 5979.0, 5996.0, 6018.0, 6011.0, 6081.0, 5979.0, 6007.0, 6014.0, 6032.0, 5881.0, 6093.0, 5937.0, 5929.0, 5975.0, 5951.0, 6118.0, 5990.0, 5963.0, 5856.0, 5945.0, 5952.0, 5922.0] Lymph-BNHL SBS9 C>G 758.0 1482.0 962.44 1279.64 4.356215354149035e-10 2.7078982242705305e-09 1.353 165551.0 Intergenic 1.955 1.33 1.47 1 1 1 359.0 485.93 431.0 543.0 [509.0, 490.0, 484.0, 484.0, 497.0, 463.0, 464.0, 483.0, 447.0, 478.0, 482.0, 467.0, 436.0, 467.0, 494.0, 500.0, 508.0, 487.0, 496.0, 502.0, 488.0, 509.0, 482.0, 503.0, 488.0, 512.0, 482.0, 482.0, 493.0, 516.0, 510.0, 495.0, 431.0, 459.0, 486.0, 472.0, 434.0, 477.0, 482.0, 483.0, 498.0, 470.0, 469.0, 482.0, 498.0, 498.0, 475.0, 472.0, 464.0, 488.0, 508.0, 490.0, 479.0, 477.0, 491.0, 508.0, 460.0, 503.0, 470.0, 486.0, 476.0, 497.0, 483.0, 451.0, 482.0, 483.0, 488.0, 519.0, 478.0, 510.0, 461.0, 488.0, 500.0, 482.0, 508.0, 504.0, 474.0, 502.0, 463.0, 470.0, 512.0, 509.0, 492.0, 442.0, 459.0, 507.0, 510.0, 543.0, 435.0, 530.0, 466.0, 493.0, 508.0, 503.0, 500.0, 485.0, 506.0, 507.0, 467.0, 492.0] 399.0 476.51 434.0 535.0 [483.0, 496.0, 487.0, 502.0, 464.0, 496.0, 494.0, 472.0, 487.0, 464.0, 464.0, 469.0, 481.0, 458.0, 434.0, 473.0, 476.0, 506.0, 485.0, 470.0, 468.0, 490.0, 456.0, 481.0, 478.0, 501.0, 499.0, 496.0, 446.0, 457.0, 476.0, 465.0, 487.0, 486.0, 484.0, 467.0, 479.0, 473.0, 498.0, 461.0, 463.0, 482.0, 475.0, 477.0, 506.0, 465.0, 464.0, 487.0, 481.0, 489.0, 463.0, 488.0, 510.0, 489.0, 467.0, 482.0, 464.0, 456.0, 482.0, 498.0, 481.0, 465.0, 465.0, 535.0, 471.0, 473.0, 461.0, 478.0, 461.0, 487.0, 441.0, 472.0, 492.0, 444.0, 452.0, 492.0, 460.0, 483.0, 492.0, 449.0, 468.0, 460.0, 463.0, 487.0, 492.0, 450.0, 478.0, 480.0, 478.0, 462.0, 491.0, 480.0, 487.0, 497.0, 464.0, 493.0, 475.0, 436.0, 472.0, 487.0] 1482.0 1279.64 1221.0 1338.0 [1257.0, 1252.0, 1266.0, 1256.0, 1279.0, 1279.0, 1285.0, 1285.0, 1308.0, 1298.0, 1296.0, 1312.0, 1323.0, 1317.0, 1310.0, 1271.0, 1259.0, 1254.0, 1267.0, 1268.0, 1286.0, 1244.0, 1307.0, 1261.0, 1276.0, 1230.0, 1268.0, 1261.0, 1304.0, 1274.0, 1259.0, 1285.0, 1328.0, 1297.0, 1269.0, 1308.0, 1327.0, 1293.0, 1266.0, 1295.0, 1278.0, 1289.0, 1298.0, 1278.0, 1241.0, 1276.0, 1305.0, 1287.0, 1295.0, 1271.0, 1269.0, 1266.0, 1254.0, 1277.0, 1280.0, 1254.0, 1314.0, 1281.0, 1290.0, 1255.0, 1285.0, 1284.0, 1292.0, 1251.0, 1287.0, 1290.0, 1291.0, 1246.0, 1304.0, 1246.0, 1338.0, 1281.0, 1248.0, 1317.0, 1279.0, 1246.0, 1311.0, 1262.0, 1288.0, 1319.0, 1263.0, 1277.0, 1286.0, 1317.0, 1288.0, 1286.0, 1252.0, 1221.0, 1324.0, 1248.0, 1286.0, 1270.0, 1241.0, 1244.0, 1278.0, 1258.0, 1258.0, 1296.0, 1306.0, 1262.0] Lymph-BNHL SBS9 C>T 1536.0 2645.0 1836.89 2349.08 3.035945776582911e-11 1.9729283048397628e-10 2.526 165551.0 Intergenic 1.722 1.279 1.347 1 1 1 786.0 935.04 883.0 996.0 [924.0, 935.0, 902.0, 915.0, 941.0, 938.0, 904.0, 946.0, 919.0, 936.0, 925.0, 934.0, 951.0, 983.0, 910.0, 955.0, 961.0, 918.0, 915.0, 961.0, 930.0, 925.0, 923.0, 927.0, 955.0, 957.0, 943.0, 921.0, 948.0, 902.0, 974.0, 922.0, 911.0, 935.0, 917.0, 951.0, 939.0, 908.0, 945.0, 962.0, 961.0, 949.0, 951.0, 926.0, 899.0, 912.0, 906.0, 906.0, 883.0, 976.0, 932.0, 938.0, 966.0, 888.0, 958.0, 907.0, 963.0, 947.0, 934.0, 931.0, 923.0, 984.0, 975.0, 932.0, 927.0, 951.0, 960.0, 903.0, 903.0, 903.0, 884.0, 984.0, 966.0, 940.0, 912.0, 913.0, 948.0, 946.0, 906.0, 917.0, 901.0, 909.0, 974.0, 951.0, 917.0, 927.0, 976.0, 965.0, 923.0, 996.0, 989.0, 940.0, 936.0, 909.0, 942.0, 947.0, 926.0, 924.0, 938.0, 936.0] 750.0 901.85 838.0 975.0 [945.0, 869.0, 975.0, 896.0, 891.0, 952.0, 884.0, 916.0, 886.0, 895.0, 861.0, 876.0, 914.0, 876.0, 899.0, 942.0, 843.0, 899.0, 860.0, 880.0, 917.0, 907.0, 838.0, 906.0, 901.0, 865.0, 917.0, 942.0, 899.0, 909.0, 875.0, 906.0, 945.0, 869.0, 896.0, 891.0, 887.0, 895.0, 937.0, 892.0, 882.0, 903.0, 901.0, 863.0, 901.0, 912.0, 907.0, 888.0, 896.0, 929.0, 926.0, 884.0, 860.0, 938.0, 928.0, 909.0, 900.0, 907.0, 859.0, 943.0, 873.0, 906.0, 917.0, 922.0, 933.0, 888.0, 886.0, 910.0, 881.0, 946.0, 950.0, 883.0, 870.0, 874.0, 900.0, 903.0, 907.0, 887.0, 922.0, 894.0, 910.0, 932.0, 899.0, 887.0, 916.0, 907.0, 869.0, 897.0, 888.0, 885.0, 929.0, 926.0, 895.0, 948.0, 915.0, 865.0, 929.0, 930.0, 925.0, 892.0] 2645.0 2349.08 2272.0 2428.0 [2330.0, 2381.0, 2313.0, 2373.0, 2349.0, 2295.0, 2401.0, 2330.0, 2389.0, 2350.0, 2402.0, 2374.0, 2328.0, 2332.0, 2376.0, 2287.0, 2384.0, 2372.0, 2416.0, 2346.0, 2335.0, 2351.0, 2428.0, 2350.0, 2340.0, 2366.0, 2323.0, 2323.0, 2330.0, 2367.0, 2334.0, 2352.0, 2327.0, 2376.0, 2367.0, 2343.0, 2355.0, 2382.0, 2306.0, 2333.0, 2342.0, 2332.0, 2332.0, 2396.0, 2386.0, 2364.0, 2363.0, 2393.0, 2407.0, 2285.0, 2330.0, 2363.0, 2356.0, 2359.0, 2299.0, 2374.0, 2322.0, 2334.0, 2388.0, 2317.0, 2388.0, 2297.0, 2303.0, 2322.0, 2323.0, 2347.0, 2337.0, 2369.0, 2401.0, 2337.0, 2350.0, 2325.0, 2349.0, 2374.0, 2379.0, 2376.0, 2329.0, 2351.0, 2354.0, 2378.0, 2377.0, 2338.0, 2321.0, 2353.0, 2353.0, 2348.0, 2342.0, 2318.0, 2370.0, 2315.0, 2272.0, 2324.0, 2343.0, 2341.0, 2330.0, 2373.0, 2327.0, 2331.0, 2327.0, 2358.0] Lymph-BNHL SBS9 T>A 9708.0 21120.0 12565.79 18314.01 2.5034196575969993e-125 5.134509174320089e-124 18.621 165551.0 Intergenic 2.176 1.457 1.493 1 1 1 4703.0 6017.75 5813.0 6184.0 [6122.0, 6127.0, 6096.0, 5916.0, 6091.0, 5932.0, 6050.0, 6072.0, 6000.0, 5963.0, 5962.0, 5996.0, 6045.0, 5855.0, 5993.0, 6076.0, 5948.0, 5813.0, 5974.0, 5909.0, 6091.0, 6015.0, 5941.0, 6002.0, 6066.0, 6078.0, 5955.0, 6067.0, 5973.0, 6042.0, 6113.0, 5940.0, 6028.0, 6034.0, 6002.0, 5929.0, 5954.0, 6019.0, 6056.0, 5936.0, 6001.0, 5973.0, 5999.0, 5985.0, 6116.0, 5940.0, 6134.0, 5940.0, 5979.0, 5877.0, 6107.0, 6179.0, 5978.0, 6103.0, 6044.0, 5946.0, 6048.0, 5988.0, 5945.0, 6040.0, 6036.0, 6184.0, 6019.0, 6091.0, 6049.0, 6107.0, 6023.0, 6018.0, 5977.0, 6078.0, 5971.0, 6052.0, 6085.0, 5992.0, 5982.0, 5968.0, 6006.0, 5992.0, 5984.0, 6034.0, 6020.0, 6123.0, 5940.0, 5986.0, 6056.0, 6030.0, 6052.0, 6025.0, 6066.0, 6024.0, 6024.0, 6094.0, 5947.0, 6019.0, 6076.0, 5938.0, 6086.0, 6109.0, 6034.0, 5975.0] 5005.0 6548.04 6340.0 6686.0 [6589.0, 6427.0, 6449.0, 6660.0, 6579.0, 6559.0, 6573.0, 6512.0, 6547.0, 6569.0, 6564.0, 6488.0, 6422.0, 6612.0, 6534.0, 6346.0, 6496.0, 6578.0, 6604.0, 6499.0, 6575.0, 6590.0, 6572.0, 6662.0, 6580.0, 6577.0, 6501.0, 6536.0, 6582.0, 6560.0, 6520.0, 6469.0, 6571.0, 6516.0, 6598.0, 6545.0, 6649.0, 6571.0, 6514.0, 6598.0, 6569.0, 6537.0, 6586.0, 6548.0, 6600.0, 6582.0, 6480.0, 6482.0, 6614.0, 6587.0, 6524.0, 6484.0, 6422.0, 6537.0, 6528.0, 6491.0, 6510.0, 6578.0, 6581.0, 6471.0, 6558.0, 6415.0, 6596.0, 6563.0, 6635.0, 6605.0, 6559.0, 6495.0, 6492.0, 6616.0, 6648.0, 6470.0, 6621.0, 6526.0, 6521.0, 6578.0, 6552.0, 6635.0, 6586.0, 6669.0, 6563.0, 6509.0, 6635.0, 6340.0, 6504.0, 6663.0, 6463.0, 6503.0, 6569.0, 6562.0, 6630.0, 6534.0, 6494.0, 6461.0, 6551.0, 6622.0, 6578.0, 6379.0, 6614.0, 6686.0] 21120.0 18314.01 18160.0 18536.0 [18181.0, 18351.0, 18316.0, 18318.0, 18196.0, 18393.0, 18246.0, 18305.0, 18335.0, 18359.0, 18337.0, 18404.0, 18397.0, 18390.0, 18373.0, 18454.0, 18428.0, 18470.0, 18321.0, 18466.0, 18224.0, 18260.0, 18358.0, 18216.0, 18246.0, 18222.0, 18436.0, 18261.0, 18302.0, 18294.0, 18237.0, 18465.0, 18287.0, 18313.0, 18297.0, 18405.0, 18281.0, 18296.0, 18322.0, 18348.0, 18309.0, 18370.0, 18294.0, 18327.0, 18173.0, 18367.0, 18269.0, 18446.0, 18297.0, 18412.0, 18257.0, 18222.0, 18472.0, 18246.0, 18305.0, 18450.0, 18327.0, 18320.0, 18346.0, 18369.0, 18309.0, 18286.0, 18261.0, 18226.0, 18190.0, 18190.0, 18293.0, 18363.0, 18422.0, 18207.0, 18264.0, 18348.0, 18160.0, 18366.0, 18370.0, 18331.0, 18286.0, 18255.0, 18305.0, 18164.0, 18320.0, 18266.0, 18308.0, 18536.0, 18319.0, 18185.0, 18343.0, 18341.0, 18250.0, 18285.0, 18225.0, 18278.0, 18421.0, 18397.0, 18250.0, 18324.0, 18225.0, 18384.0, 18239.0, 18221.0] Lymph-BNHL SBS9 T>C 13097.0 25140.0 16086.45 22207.77 3.479629823713155e-108 6.532109076043582e-107 23.097 165551.0 Intergenic 1.92 1.381 1.39 1 1 1 6258.0 7595.24 7366.0 7853.0 [7489.0, 7542.0, 7507.0, 7570.0, 7571.0, 7641.0, 7414.0, 7711.0, 7665.0, 7748.0, 7651.0, 7469.0, 7697.0, 7574.0, 7433.0, 7534.0, 7623.0, 7547.0, 7659.0, 7626.0, 7571.0, 7615.0, 7574.0, 7541.0, 7557.0, 7624.0, 7553.0, 7690.0, 7679.0, 7739.0, 7576.0, 7590.0, 7552.0, 7663.0, 7479.0, 7601.0, 7633.0, 7553.0, 7686.0, 7539.0, 7597.0, 7588.0, 7680.0, 7691.0, 7628.0, 7608.0, 7566.0, 7690.0, 7647.0, 7676.0, 7561.0, 7648.0, 7653.0, 7610.0, 7580.0, 7593.0, 7366.0, 7481.0, 7520.0, 7520.0, 7640.0, 7764.0, 7667.0, 7535.0, 7608.0, 7688.0, 7491.0, 7581.0, 7567.0, 7490.0, 7523.0, 7759.0, 7546.0, 7600.0, 7599.0, 7474.0, 7586.0, 7612.0, 7554.0, 7561.0, 7681.0, 7547.0, 7734.0, 7550.0, 7483.0, 7629.0, 7480.0, 7624.0, 7441.0, 7624.0, 7503.0, 7699.0, 7717.0, 7638.0, 7853.0, 7593.0, 7583.0, 7630.0, 7497.0, 7584.0] 6839.0 8491.21 8308.0 8657.0 [8564.0, 8473.0, 8497.0, 8540.0, 8498.0, 8605.0, 8398.0, 8378.0, 8507.0, 8450.0, 8377.0, 8509.0, 8497.0, 8423.0, 8514.0, 8580.0, 8524.0, 8514.0, 8474.0, 8590.0, 8522.0, 8462.0, 8538.0, 8542.0, 8465.0, 8506.0, 8535.0, 8365.0, 8500.0, 8360.0, 8507.0, 8593.0, 8457.0, 8650.0, 8556.0, 8502.0, 8445.0, 8428.0, 8554.0, 8473.0, 8501.0, 8356.0, 8457.0, 8368.0, 8529.0, 8342.0, 8657.0, 8406.0, 8419.0, 8349.0, 8634.0, 8498.0, 8624.0, 8506.0, 8558.0, 8553.0, 8569.0, 8406.0, 8516.0, 8503.0, 8368.0, 8490.0, 8453.0, 8532.0, 8420.0, 8308.0, 8653.0, 8436.0, 8523.0, 8584.0, 8622.0, 8390.0, 8322.0, 8483.0, 8580.0, 8490.0, 8396.0, 8478.0, 8616.0, 8462.0, 8481.0, 8401.0, 8572.0, 8545.0, 8490.0, 8491.0, 8503.0, 8551.0, 8547.0, 8355.0, 8422.0, 8478.0, 8429.0, 8421.0, 8574.0, 8546.0, 8502.0, 8543.0, 8535.0, 8506.0] 25140.0 22207.77 21876.0 22481.0 [22250.0, 22303.0, 22291.0, 22191.0, 22218.0, 22043.0, 22481.0, 22200.0, 22139.0, 22113.0, 22259.0, 22311.0, 22111.0, 22313.0, 22352.0, 22174.0, 22135.0, 22223.0, 22154.0, 22088.0, 22208.0, 22229.0, 22166.0, 22194.0, 22277.0, 22163.0, 22206.0, 22216.0, 22091.0, 22202.0, 22205.0, 22115.0, 22285.0, 22007.0, 22245.0, 22183.0, 22210.0, 22314.0, 22066.0, 22273.0, 22199.0, 22328.0, 22155.0, 22232.0, 22151.0, 22327.0, 22072.0, 22189.0, 22232.0, 22277.0, 22114.0, 22135.0, 22037.0, 22193.0, 22164.0, 22157.0, 22355.0, 22415.0, 22253.0, 22251.0, 22271.0, 22041.0, 22174.0, 22222.0, 22255.0, 22307.0, 22165.0, 22276.0, 22195.0, 22217.0, 22135.0, 22161.0, 22399.0, 22223.0, 22103.0, 22342.0, 22313.0, 22185.0, 22115.0, 22288.0, 22137.0, 22358.0, 21987.0, 22214.0, 22314.0, 22177.0, 22290.0, 22119.0, 22308.0, 22306.0, 22379.0, 22123.0, 22158.0, 22244.0, 21876.0, 22181.0, 22190.0, 22130.0, 22263.0, 22196.0] Lymph-BNHL SBS9 T>G 24011.0 55748.0 32783.85 47136.98 0.0 0.0 48.178 165551.0 Intergenic 2.322 1.438 1.615 1 1 1 1 11387.0 15639.39 15377.0 15931.0 [15673.0, 15715.0, 15799.0, 15594.0, 15867.0, 15706.0, 15632.0, 15582.0, 15854.0, 15644.0, 15501.0, 15550.0, 15682.0, 15711.0, 15652.0, 15673.0, 15491.0, 15759.0, 15561.0, 15681.0, 15814.0, 15507.0, 15655.0, 15931.0, 15591.0, 15670.0, 15716.0, 15450.0, 15539.0, 15601.0, 15616.0, 15491.0, 15702.0, 15709.0, 15699.0, 15613.0, 15732.0, 15649.0, 15691.0, 15614.0, 15682.0, 15666.0, 15626.0, 15447.0, 15568.0, 15497.0, 15676.0, 15562.0, 15655.0, 15704.0, 15533.0, 15757.0, 15659.0, 15676.0, 15377.0, 15633.0, 15706.0, 15640.0, 15545.0, 15588.0, 15565.0, 15716.0, 15595.0, 15584.0, 15777.0, 15530.0, 15610.0, 15508.0, 15570.0, 15620.0, 15662.0, 15589.0, 15621.0, 15741.0, 15586.0, 15642.0, 15606.0, 15477.0, 15727.0, 15620.0, 15759.0, 15634.0, 15707.0, 15490.0, 15769.0, 15662.0, 15861.0, 15561.0, 15696.0, 15726.0, 15590.0, 15479.0, 15732.0, 15610.0, 15632.0, 15801.0, 15704.0, 15503.0, 15648.0, 15515.0] 12624.0 17144.46 16863.0 17476.0 [17316.0, 17215.0, 17258.0, 17050.0, 17322.0, 16989.0, 17292.0, 16977.0, 17035.0, 17134.0, 17033.0, 17197.0, 17241.0, 17091.0, 17037.0, 17266.0, 17414.0, 17112.0, 17229.0, 17027.0, 17221.0, 17131.0, 17286.0, 16985.0, 17184.0, 17168.0, 17186.0, 16920.0, 17081.0, 17113.0, 17071.0, 17293.0, 17248.0, 17242.0, 17155.0, 17224.0, 17215.0, 17038.0, 17036.0, 17237.0, 17163.0, 17222.0, 17146.0, 17129.0, 17071.0, 16969.0, 17252.0, 17476.0, 17082.0, 17130.0, 17143.0, 16983.0, 17090.0, 17099.0, 17341.0, 17118.0, 17018.0, 17073.0, 17153.0, 17237.0, 17057.0, 17010.0, 17236.0, 17181.0, 17167.0, 17293.0, 17273.0, 17147.0, 17131.0, 17190.0, 17037.0, 17216.0, 17120.0, 17101.0, 17209.0, 17310.0, 17021.0, 17232.0, 17167.0, 17149.0, 17149.0, 17186.0, 17120.0, 17091.0, 17055.0, 17044.0, 17295.0, 17114.0, 17071.0, 17034.0, 17057.0, 17319.0, 17046.0, 17085.0, 17237.0, 17046.0, 17102.0, 17065.0, 17056.0, 16863.0] 55748.0 47136.98 46764.0 47550.0 [46945.0, 46981.0, 46886.0, 47286.0, 46764.0, 47229.0, 46997.0, 47342.0, 47044.0, 47136.0, 47375.0, 47162.0, 47039.0, 47134.0, 47228.0, 46972.0, 47021.0, 47046.0, 47136.0, 47205.0, 46878.0, 47264.0, 46963.0, 46973.0, 47145.0, 47112.0, 46997.0, 47550.0, 47279.0, 47232.0, 47187.0, 47141.0, 46960.0, 46998.0, 47055.0, 47087.0, 46982.0, 47263.0, 47165.0, 47045.0, 47085.0, 47071.0, 47166.0, 47320.0, 47273.0, 47480.0, 47004.0, 46881.0, 47178.0, 47081.0, 47201.0, 47172.0, 47177.0, 47146.0, 47217.0, 47146.0, 47192.0, 47196.0, 47278.0, 47118.0, 47301.0, 47223.0, 47100.0, 47154.0, 46972.0, 47087.0, 47041.0, 47272.0, 47243.0, 47115.0, 47213.0, 47093.0, 47188.0, 47065.0, 47133.0, 46947.0, 47287.0, 47207.0, 47037.0, 47157.0, 46987.0, 47130.0, 47099.0, 47326.0, 47091.0, 47193.0, 46767.0, 47223.0, 47138.0, 47157.0, 47249.0, 47134.0, 47168.0, 47247.0, 47056.0, 47104.0, 47138.0, 47337.0, 47195.0, 47538.0] Lymph-CLL SBS9 C>A 525.0 1313.0 758.38 1080.72 8.691280698303881e-16 6.583120856000815e-15 4.634 39663.0 Intergenic 2.501 1.425 1.755 1 1 1 1 1 291.0 374.49 334.0 418.0 [370.0, 364.0, 389.0, 359.0, 349.0, 393.0, 363.0, 378.0, 352.0, 375.0, 392.0, 395.0, 380.0, 364.0, 355.0, 363.0, 386.0, 374.0, 377.0, 378.0, 361.0, 395.0, 347.0, 366.0, 390.0, 353.0, 372.0, 403.0, 363.0, 359.0, 372.0, 388.0, 363.0, 341.0, 383.0, 362.0, 370.0, 385.0, 354.0, 409.0, 353.0, 351.0, 397.0, 350.0, 354.0, 384.0, 388.0, 374.0, 398.0, 377.0, 380.0, 372.0, 398.0, 366.0, 357.0, 366.0, 363.0, 404.0, 384.0, 352.0, 389.0, 397.0, 377.0, 379.0, 392.0, 371.0, 367.0, 353.0, 381.0, 362.0, 353.0, 395.0, 391.0, 418.0, 369.0, 334.0, 397.0, 391.0, 368.0, 390.0, 393.0, 376.0, 375.0, 389.0, 398.0, 388.0, 351.0, 372.0, 398.0, 376.0, 352.0, 353.0, 371.0, 370.0, 361.0, 395.0, 388.0, 401.0, 343.0, 365.0] 234.0 383.89 337.0 421.0 [361.0, 387.0, 368.0, 414.0, 400.0, 397.0, 371.0, 385.0, 364.0, 355.0, 337.0, 385.0, 361.0, 390.0, 400.0, 385.0, 367.0, 376.0, 379.0, 408.0, 393.0, 381.0, 408.0, 401.0, 386.0, 409.0, 396.0, 376.0, 390.0, 385.0, 393.0, 372.0, 357.0, 374.0, 379.0, 388.0, 398.0, 388.0, 392.0, 366.0, 382.0, 397.0, 352.0, 378.0, 383.0, 384.0, 353.0, 378.0, 397.0, 421.0, 384.0, 364.0, 375.0, 381.0, 388.0, 386.0, 397.0, 372.0, 391.0, 398.0, 395.0, 379.0, 395.0, 364.0, 405.0, 402.0, 374.0, 401.0, 360.0, 386.0, 381.0, 371.0, 401.0, 374.0, 399.0, 382.0, 395.0, 384.0, 384.0, 395.0, 400.0, 375.0, 346.0, 358.0, 395.0, 379.0, 382.0, 411.0, 391.0, 378.0, 377.0, 369.0, 413.0, 376.0, 392.0, 374.0, 404.0, 386.0, 388.0, 385.0] 1313.0 1080.72 1035.0 1124.0 [1106.0, 1087.0, 1083.0, 1069.0, 1091.0, 1051.0, 1101.0, 1073.0, 1122.0, 1111.0, 1114.0, 1059.0, 1098.0, 1085.0, 1082.0, 1087.0, 1085.0, 1088.0, 1084.0, 1057.0, 1086.0, 1066.0, 1077.0, 1078.0, 1065.0, 1076.0, 1067.0, 1060.0, 1086.0, 1094.0, 1075.0, 1082.0, 1117.0, 1124.0, 1078.0, 1089.0, 1071.0, 1073.0, 1090.0, 1067.0, 1105.0, 1090.0, 1091.0, 1112.0, 1102.0, 1071.0, 1094.0, 1093.0, 1042.0, 1041.0, 1080.0, 1102.0, 1067.0, 1091.0, 1090.0, 1093.0, 1077.0, 1060.0, 1063.0, 1092.0, 1058.0, 1062.0, 1067.0, 1094.0, 1035.0, 1069.0, 1105.0, 1082.0, 1097.0, 1088.0, 1105.0, 1077.0, 1046.0, 1049.0, 1075.0, 1118.0, 1046.0, 1066.0, 1086.0, 1056.0, 1051.0, 1086.0, 1114.0, 1089.0, 1049.0, 1070.0, 1104.0, 1056.0, 1054.0, 1084.0, 1110.0, 1113.0, 1057.0, 1092.0, 1084.0, 1071.0, 1048.0, 1051.0, 1109.0, 1089.0] Lymph-CLL SBS9 C>G 49.0 123.0 73.72 99.17 0.009402760859999507 0.0341893823934538 0.434 39663.0 Intergenic 2.51 1.345 1.866 1 1 1 1 1 19.0 36.51 24.0 50.0 [36.0, 35.0, 35.0, 32.0, 39.0, 35.0, 42.0, 34.0, 32.0, 38.0, 28.0, 32.0, 39.0, 38.0, 40.0, 37.0, 35.0, 34.0, 27.0, 35.0, 34.0, 37.0, 24.0, 42.0, 44.0, 41.0, 37.0, 38.0, 37.0, 35.0, 37.0, 31.0, 44.0, 39.0, 35.0, 33.0, 29.0, 37.0, 39.0, 39.0, 34.0, 35.0, 28.0, 27.0, 47.0, 36.0, 32.0, 30.0, 31.0, 42.0, 42.0, 36.0, 29.0, 31.0, 33.0, 37.0, 38.0, 44.0, 40.0, 29.0, 40.0, 38.0, 40.0, 34.0, 37.0, 37.0, 44.0, 32.0, 44.0, 33.0, 33.0, 43.0, 46.0, 28.0, 33.0, 32.0, 47.0, 34.0, 37.0, 39.0, 47.0, 34.0, 38.0, 28.0, 31.0, 49.0, 34.0, 40.0, 40.0, 38.0, 50.0, 46.0, 42.0, 41.0, 31.0, 28.0, 34.0, 35.0, 40.0, 38.0] 30.0 37.21 24.0 50.0 [29.0, 42.0, 44.0, 36.0, 33.0, 47.0, 32.0, 34.0, 35.0, 38.0, 38.0, 44.0, 33.0, 36.0, 32.0, 37.0, 27.0, 45.0, 50.0, 35.0, 38.0, 40.0, 24.0, 42.0, 35.0, 50.0, 37.0, 42.0, 41.0, 38.0, 39.0, 38.0, 43.0, 37.0, 43.0, 27.0, 41.0, 41.0, 35.0, 38.0, 45.0, 35.0, 38.0, 30.0, 30.0, 37.0, 44.0, 46.0, 32.0, 32.0, 40.0, 33.0, 43.0, 36.0, 30.0, 29.0, 34.0, 33.0, 40.0, 39.0, 30.0, 28.0, 37.0, 40.0, 39.0, 37.0, 42.0, 43.0, 38.0, 42.0, 41.0, 39.0, 26.0, 40.0, 37.0, 45.0, 30.0, 42.0, 38.0, 37.0, 37.0, 34.0, 35.0, 41.0, 43.0, 35.0, 42.0, 30.0, 37.0, 35.0, 42.0, 31.0, 29.0, 36.0, 37.0, 39.0, 29.0, 29.0, 43.0, 44.0] 123.0 99.17 82.0 124.0 [107.0, 95.0, 94.0, 105.0, 100.0, 93.0, 99.0, 104.0, 107.0, 96.0, 106.0, 99.0, 101.0, 98.0, 100.0, 99.0, 111.0, 95.0, 95.0, 102.0, 100.0, 97.0, 124.0, 90.0, 94.0, 82.0, 98.0, 92.0, 97.0, 99.0, 96.0, 103.0, 86.0, 96.0, 96.0, 113.0, 102.0, 96.0, 100.0, 95.0, 94.0, 103.0, 106.0, 115.0, 97.0, 100.0, 98.0, 97.0, 110.0, 100.0, 90.0, 103.0, 101.0, 107.0, 110.0, 106.0, 100.0, 95.0, 94.0, 106.0, 104.0, 106.0, 97.0, 99.0, 97.0, 99.0, 87.0, 97.0, 90.0, 97.0, 100.0, 90.0, 100.0, 108.0, 102.0, 98.0, 95.0, 96.0, 98.0, 98.0, 90.0, 104.0, 99.0, 103.0, 99.0, 89.0, 97.0, 102.0, 95.0, 101.0, 82.0, 96.0, 101.0, 96.0, 105.0, 105.0, 110.0, 109.0, 90.0, 92.0] Lymph-CLL SBS9 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 39663.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Lymph-CLL SBS9 T>A 1656.0 3924.0 2273.65 3323.53 8.028647664543488e-34 8.393316119982049e-33 14.069 39663.0 Intergenic 2.37 1.462 1.621 1 1 1 1 829.0 1077.71 1011.0 1164.0 [1057.0, 1035.0, 1116.0, 1059.0, 1043.0, 1036.0, 1083.0, 1038.0, 1128.0, 1037.0, 1087.0, 1072.0, 1061.0, 1097.0, 1080.0, 1055.0, 1064.0, 1124.0, 1011.0, 1069.0, 1111.0, 1055.0, 1044.0, 1067.0, 1063.0, 1058.0, 1095.0, 1083.0, 1038.0, 1105.0, 1109.0, 1052.0, 1055.0, 1079.0, 1067.0, 1083.0, 1037.0, 1072.0, 1114.0, 1062.0, 1070.0, 1109.0, 1092.0, 1043.0, 1130.0, 1056.0, 1089.0, 1032.0, 1056.0, 1097.0, 1127.0, 1087.0, 1094.0, 1086.0, 1048.0, 1018.0, 1126.0, 1056.0, 1072.0, 1051.0, 1061.0, 1109.0, 1087.0, 1119.0, 1073.0, 1098.0, 1030.0, 1164.0, 1080.0, 1038.0, 1079.0, 1085.0, 1075.0, 1058.0, 1071.0, 1031.0, 1099.0, 1115.0, 1048.0, 1153.0, 1085.0, 1080.0, 1124.0, 1105.0, 1078.0, 1120.0, 1142.0, 1096.0, 1094.0, 1051.0, 1065.0, 1016.0, 1073.0, 1106.0, 1094.0, 1095.0, 1079.0, 1102.0, 1081.0, 1072.0] 827.0 1195.94 1115.0 1280.0 [1168.0, 1229.0, 1206.0, 1175.0, 1189.0, 1172.0, 1218.0, 1219.0, 1173.0, 1246.0, 1221.0, 1204.0, 1159.0, 1190.0, 1210.0, 1186.0, 1207.0, 1191.0, 1225.0, 1212.0, 1176.0, 1220.0, 1266.0, 1170.0, 1119.0, 1186.0, 1167.0, 1190.0, 1225.0, 1198.0, 1180.0, 1211.0, 1187.0, 1203.0, 1166.0, 1220.0, 1158.0, 1234.0, 1215.0, 1171.0, 1208.0, 1252.0, 1178.0, 1208.0, 1149.0, 1194.0, 1210.0, 1218.0, 1173.0, 1243.0, 1115.0, 1241.0, 1246.0, 1162.0, 1227.0, 1139.0, 1178.0, 1191.0, 1206.0, 1280.0, 1262.0, 1155.0, 1228.0, 1181.0, 1219.0, 1201.0, 1232.0, 1154.0, 1151.0, 1177.0, 1185.0, 1244.0, 1209.0, 1153.0, 1237.0, 1186.0, 1199.0, 1238.0, 1161.0, 1199.0, 1219.0, 1178.0, 1181.0, 1175.0, 1190.0, 1191.0, 1124.0, 1185.0, 1197.0, 1157.0, 1207.0, 1254.0, 1195.0, 1176.0, 1153.0, 1201.0, 1180.0, 1207.0, 1200.0, 1173.0] 3924.0 3323.53 3230.0 3440.0 [3370.0, 3325.0, 3282.0, 3370.0, 3363.0, 3390.0, 3294.0, 3336.0, 3305.0, 3316.0, 3291.0, 3316.0, 3374.0, 3306.0, 3308.0, 3350.0, 3325.0, 3291.0, 3365.0, 3315.0, 3312.0, 3321.0, 3287.0, 3361.0, 3409.0, 3355.0, 3332.0, 3326.0, 3332.0, 3291.0, 3306.0, 3327.0, 3345.0, 3319.0, 3361.0, 3296.0, 3401.0, 3286.0, 3268.0, 3356.0, 3319.0, 3230.0, 3331.0, 3345.0, 3316.0, 3352.0, 3299.0, 3355.0, 3372.0, 3266.0, 3351.0, 3268.0, 3267.0, 3347.0, 3324.0, 3440.0, 3296.0, 3346.0, 3316.0, 3262.0, 3280.0, 3330.0, 3280.0, 3301.0, 3307.0, 3292.0, 3335.0, 3289.0, 3369.0, 3386.0, 3331.0, 3267.0, 3314.0, 3385.0, 3296.0, 3378.0, 3295.0, 3241.0, 3381.0, 3245.0, 3297.0, 3340.0, 3291.0, 3315.0, 3328.0, 3288.0, 3329.0, 3316.0, 3306.0, 3384.0, 3323.0, 3333.0, 3331.0, 3319.0, 3350.0, 3301.0, 3346.0, 3298.0, 3313.0, 3358.0] Lymph-CLL SBS9 T>C 2466.0 4930.0 3103.25 4309.07 1.0578802102657207e-26 9.888423702409354e-26 18.647 39663.0 Intergenic 1.999 1.389 1.44 1 1 1 1188.0 1453.1 1335.0 1523.0 [1438.0, 1444.0, 1463.0, 1458.0, 1435.0, 1511.0, 1430.0, 1449.0, 1504.0, 1456.0, 1492.0, 1464.0, 1454.0, 1429.0, 1475.0, 1470.0, 1415.0, 1498.0, 1412.0, 1469.0, 1404.0, 1442.0, 1371.0, 1473.0, 1422.0, 1428.0, 1503.0, 1453.0, 1398.0, 1467.0, 1486.0, 1424.0, 1448.0, 1437.0, 1335.0, 1486.0, 1411.0, 1455.0, 1462.0, 1446.0, 1467.0, 1437.0, 1375.0, 1450.0, 1444.0, 1446.0, 1429.0, 1502.0, 1394.0, 1428.0, 1450.0, 1412.0, 1439.0, 1462.0, 1404.0, 1504.0, 1448.0, 1438.0, 1431.0, 1434.0, 1421.0, 1427.0, 1463.0, 1504.0, 1523.0, 1502.0, 1411.0, 1504.0, 1486.0, 1384.0, 1447.0, 1450.0, 1442.0, 1495.0, 1430.0, 1447.0, 1504.0, 1460.0, 1427.0, 1477.0, 1495.0, 1459.0, 1492.0, 1486.0, 1448.0, 1494.0, 1481.0, 1435.0, 1407.0, 1521.0, 1490.0, 1452.0, 1470.0, 1481.0, 1461.0, 1457.0, 1487.0, 1406.0, 1467.0, 1506.0] 1278.0 1650.15 1545.0 1758.0 [1610.0, 1657.0, 1690.0, 1679.0, 1664.0, 1601.0, 1607.0, 1639.0, 1635.0, 1702.0, 1653.0, 1713.0, 1610.0, 1593.0, 1636.0, 1605.0, 1661.0, 1685.0, 1598.0, 1600.0, 1633.0, 1641.0, 1680.0, 1700.0, 1648.0, 1674.0, 1688.0, 1661.0, 1625.0, 1657.0, 1600.0, 1685.0, 1670.0, 1651.0, 1677.0, 1658.0, 1641.0, 1612.0, 1651.0, 1661.0, 1610.0, 1616.0, 1684.0, 1646.0, 1685.0, 1653.0, 1639.0, 1602.0, 1670.0, 1607.0, 1682.0, 1624.0, 1658.0, 1652.0, 1665.0, 1632.0, 1638.0, 1623.0, 1706.0, 1633.0, 1624.0, 1636.0, 1669.0, 1619.0, 1650.0, 1697.0, 1679.0, 1700.0, 1666.0, 1628.0, 1639.0, 1679.0, 1635.0, 1588.0, 1744.0, 1661.0, 1639.0, 1649.0, 1729.0, 1661.0, 1657.0, 1656.0, 1660.0, 1642.0, 1545.0, 1644.0, 1673.0, 1707.0, 1717.0, 1652.0, 1650.0, 1584.0, 1575.0, 1758.0, 1570.0, 1646.0, 1665.0, 1648.0, 1638.0, 1660.0] 4930.0 4309.07 4194.0 4412.0 [4374.0, 4322.0, 4257.0, 4267.0, 4307.0, 4294.0, 4367.0, 4321.0, 4272.0, 4253.0, 4275.0, 4229.0, 4346.0, 4396.0, 4301.0, 4336.0, 4331.0, 4230.0, 4397.0, 4352.0, 4374.0, 4324.0, 4356.0, 4232.0, 4345.0, 4314.0, 4214.0, 4305.0, 4378.0, 4291.0, 4339.0, 4302.0, 4284.0, 4329.0, 4397.0, 4271.0, 4354.0, 4345.0, 4297.0, 4303.0, 4344.0, 4358.0, 4357.0, 4317.0, 4298.0, 4310.0, 4347.0, 4301.0, 4359.0, 4374.0, 4272.0, 4384.0, 4325.0, 4297.0, 4341.0, 4275.0, 4323.0, 4349.0, 4273.0, 4347.0, 4368.0, 4348.0, 4274.0, 4286.0, 4229.0, 4217.0, 4320.0, 4219.0, 4262.0, 4397.0, 4328.0, 4276.0, 4335.0, 4323.0, 4243.0, 4295.0, 4272.0, 4300.0, 4255.0, 4267.0, 4260.0, 4300.0, 4265.0, 4288.0, 4412.0, 4273.0, 4259.0, 4282.0, 4288.0, 4243.0, 4277.0, 4379.0, 4370.0, 4194.0, 4386.0, 4307.0, 4260.0, 4359.0, 4308.0, 4251.0] Lymph-CLL SBS9 T>G 6856.0 17821.0 10011.08 14731.3 7.36289449397636e-195 1.9128292109523413e-193 62.217 39663.0 Intergenic 2.599 1.471 1.766 1 1 1 1 1 3256.0 4777.39 4640.0 4916.0 [4814.0, 4733.0, 4787.0, 4738.0, 4730.0, 4796.0, 4778.0, 4868.0, 4840.0, 4794.0, 4771.0, 4876.0, 4796.0, 4706.0, 4907.0, 4760.0, 4750.0, 4796.0, 4869.0, 4710.0, 4706.0, 4813.0, 4781.0, 4727.0, 4721.0, 4881.0, 4668.0, 4725.0, 4716.0, 4843.0, 4678.0, 4782.0, 4724.0, 4784.0, 4731.0, 4796.0, 4854.0, 4825.0, 4741.0, 4743.0, 4815.0, 4737.0, 4670.0, 4760.0, 4837.0, 4775.0, 4778.0, 4805.0, 4733.0, 4835.0, 4695.0, 4724.0, 4858.0, 4725.0, 4745.0, 4712.0, 4758.0, 4776.0, 4830.0, 4705.0, 4784.0, 4782.0, 4810.0, 4762.0, 4737.0, 4863.0, 4810.0, 4747.0, 4816.0, 4781.0, 4847.0, 4787.0, 4814.0, 4720.0, 4674.0, 4873.0, 4713.0, 4916.0, 4876.0, 4900.0, 4728.0, 4800.0, 4739.0, 4829.0, 4875.0, 4682.0, 4640.0, 4814.0, 4753.0, 4739.0, 4780.0, 4796.0, 4731.0, 4895.0, 4764.0, 4728.0, 4815.0, 4750.0, 4785.0, 4753.0] 3600.0 5233.69 5048.0 5366.0 [5212.0, 5283.0, 5216.0, 5252.0, 5307.0, 5048.0, 5265.0, 5195.0, 5237.0, 5242.0, 5219.0, 5212.0, 5209.0, 5210.0, 5122.0, 5216.0, 5245.0, 5154.0, 5213.0, 5366.0, 5288.0, 5225.0, 5166.0, 5320.0, 5191.0, 5285.0, 5313.0, 5345.0, 5154.0, 5220.0, 5251.0, 5209.0, 5292.0, 5211.0, 5174.0, 5218.0, 5192.0, 5318.0, 5312.0, 5232.0, 5246.0, 5158.0, 5259.0, 5306.0, 5263.0, 5251.0, 5259.0, 5280.0, 5274.0, 5190.0, 5283.0, 5237.0, 5233.0, 5332.0, 5275.0, 5265.0, 5257.0, 5132.0, 5236.0, 5245.0, 5232.0, 5206.0, 5240.0, 5251.0, 5219.0, 5216.0, 5096.0, 5202.0, 5164.0, 5271.0, 5278.0, 5205.0, 5126.0, 5275.0, 5256.0, 5161.0, 5359.0, 5198.0, 5157.0, 5152.0, 5268.0, 5201.0, 5183.0, 5160.0, 5272.0, 5303.0, 5314.0, 5172.0, 5167.0, 5189.0, 5212.0, 5224.0, 5257.0, 5215.0, 5311.0, 5313.0, 5189.0, 5239.0, 5277.0, 5319.0] 17821.0 14731.3 14573.0 14895.0 [14717.0, 14709.0, 14745.0, 14760.0, 14697.0, 14895.0, 14686.0, 14683.0, 14692.0, 14702.0, 14769.0, 14661.0, 14733.0, 14817.0, 14706.0, 14768.0, 14737.0, 14783.0, 14659.0, 14673.0, 14751.0, 14708.0, 14787.0, 14702.0, 14833.0, 14573.0, 14763.0, 14666.0, 14858.0, 14661.0, 14816.0, 14753.0, 14718.0, 14746.0, 14822.0, 14706.0, 14699.0, 14612.0, 14692.0, 14769.0, 14684.0, 14852.0, 14817.0, 14679.0, 14646.0, 14724.0, 14703.0, 14657.0, 14759.0, 14731.0, 14779.0, 14781.0, 14662.0, 14682.0, 14698.0, 14778.0, 14727.0, 14820.0, 14676.0, 14793.0, 14726.0, 14751.0, 14693.0, 14726.0, 14781.0, 14658.0, 14848.0, 14788.0, 14757.0, 14675.0, 14638.0, 14773.0, 14806.0, 14748.0, 14821.0, 14720.0, 14682.0, 14622.0, 14698.0, 14680.0, 14749.0, 14732.0, 14819.0, 14742.0, 14599.0, 14751.0, 14794.0, 14753.0, 14811.0, 14818.0, 14748.0, 14712.0, 14762.0, 14638.0, 14671.0, 14708.0, 14755.0, 14738.0, 14670.0, 14694.0] Skin-Melanoma SBS9 C>A 247.0 417.0 287.88 376.18 0.025183476962151057 0.08437547380648357 7.557 8786.0 Intergenic 1.688 1.307 1.292 1 1 124.0 142.06 117.0 168.0 [148, 149, 150, 151, 153, 159, 154, 136, 135, 134, 126, 142, 140, 123, 146, 132, 152, 142, 153, 143, 147, 140, 168, 149, 142, 148, 140, 162, 131, 133, 137, 126, 134, 128, 166, 150, 142, 147, 140, 144, 140, 160, 135, 133, 123, 137, 137, 155, 157, 149, 147, 146, 142, 143, 136, 135, 148, 126, 127, 153, 136, 140, 150, 136, 133, 143, 138, 144, 135, 152, 138, 154, 141, 134, 150, 154, 141, 165, 142, 143, 149, 134, 132, 125, 128, 155, 117, 145, 153, 141, 131, 133, 147, 132, 134, 145, 152, 147, 138, 128] 123.0 145.82 114.0 168.0 [148, 148, 157, 149, 151, 135, 131, 165, 146, 141, 138, 160, 163, 163, 128, 129, 146, 142, 139, 145, 156, 149, 149, 147, 146, 126, 145, 156, 149, 149, 151, 138, 150, 159, 146, 138, 148, 137, 144, 161, 152, 115, 145, 149, 155, 163, 155, 163, 137, 153, 148, 146, 139, 149, 132, 139, 154, 137, 139, 129, 140, 146, 136, 152, 147, 140, 168, 133, 154, 130, 158, 152, 153, 153, 143, 114, 152, 121, 153, 143, 127, 155, 156, 136, 142, 154, 135, 154, 134, 121, 139, 156, 147, 137, 168, 159, 141, 158, 167, 141] 417.0 376.18 344.0 410.0 [370, 370, 358, 363, 358, 371, 377, 362, 382, 390, 398, 363, 360, 381, 390, 406, 366, 381, 372, 376, 364, 374, 346, 369, 377, 389, 380, 344, 383, 380, 376, 400, 378, 378, 351, 377, 377, 379, 378, 362, 373, 391, 385, 381, 384, 367, 370, 346, 369, 360, 367, 372, 381, 375, 396, 388, 361, 400, 398, 379, 386, 380, 379, 377, 385, 384, 360, 390, 375, 383, 367, 356, 371, 374, 375, 396, 374, 380, 369, 376, 388, 373, 373, 402, 393, 354, 410, 367, 377, 404, 393, 375, 368, 395, 363, 361, 370, 362, 360, 394] Skin-Melanoma SBS9 C>G 75.0 139.0 89.24 125.89 0.19610271800575865 0.4867595982972552 2.436 8786.0 Intergenic 1.853 1.411 1.314 1 1 1 42.0 47.06 37.0 63.0 [45, 50, 43, 42, 54, 49, 41, 50, 39, 59, 45, 62, 48, 49, 47, 63, 50, 54, 50, 48, 51, 51, 42, 43, 41, 45, 52, 58, 60, 63, 38, 53, 47, 41, 47, 45, 49, 47, 43, 44, 42, 39, 50, 51, 54, 37, 46, 45, 50, 39, 49, 50, 49, 40, 45, 50, 42, 55, 42, 41, 38, 44, 47, 49, 41, 48, 41, 43, 44, 51, 42, 44, 37, 46, 55, 50, 45, 55, 41, 44, 42, 42, 44, 42, 52, 49, 37, 50, 37, 61, 48, 50, 50, 43, 48, 46, 44, 58, 49, 45] 33.0 42.18 27.0 57.0 [45, 40, 40, 36, 43, 48, 43, 33, 42, 37, 45, 44, 46, 44, 40, 42, 39, 39, 49, 27, 43, 45, 45, 46, 48, 41, 37, 40, 34, 36, 38, 50, 48, 36, 37, 41, 40, 47, 37, 44, 36, 51, 35, 46, 52, 37, 43, 44, 37, 37, 29, 44, 27, 50, 37, 29, 43, 37, 46, 50, 44, 51, 57, 40, 40, 45, 48, 43, 45, 50, 50, 49, 47, 44, 32, 45, 40, 35, 52, 39, 51, 36, 45, 51, 39, 46, 42, 44, 42, 35, 56, 37, 46, 48, 32, 38, 43, 43, 44, 39] 139.0 125.89 109.0 140.0 [124, 125, 132, 137, 119, 120, 132, 132, 133, 121, 126, 112, 121, 121, 128, 110, 127, 122, 118, 139, 121, 118, 129, 125, 126, 129, 125, 119, 120, 116, 138, 114, 119, 138, 132, 128, 125, 120, 135, 126, 137, 125, 130, 118, 109, 140, 125, 128, 128, 138, 138, 120, 138, 125, 132, 136, 130, 123, 127, 125, 134, 122, 111, 126, 134, 121, 126, 128, 125, 115, 125, 123, 131, 125, 131, 120, 130, 124, 122, 132, 121, 136, 129, 123, 124, 120, 136, 124, 136, 118, 112, 128, 118, 123, 134, 130, 129, 115, 123, 131] Skin-Melanoma SBS9 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 8786.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Skin-Melanoma SBS9 T>A 157.0 245.0 173.73 229.17 0.28218390168314483 0.6390701949741923 4.575 8786.0 Intergenic 1.561 1.319 1.183 1 63.0 82.07 64.0 101.0 [91, 84, 73, 84, 83, 84, 91, 93, 79, 76, 71, 96, 70, 76, 80, 99, 84, 85, 83, 93, 71, 81, 80, 101, 89, 79, 87, 88, 74, 82, 91, 67, 79, 79, 97, 75, 85, 74, 84, 83, 98, 70, 81, 64, 79, 91, 86, 79, 76, 78, 75, 76, 90, 93, 87, 82, 77, 86, 73, 93, 82, 82, 80, 79, 80, 69, 99, 81, 80, 80, 78, 82, 76, 84, 85, 72, 77, 87, 66, 78, 76, 87, 79, 93, 91, 88, 89, 89, 80, 81, 83, 76, 83, 86, 75, 73, 91, 68, 88, 79] 94.0 91.66 68.0 114.0 [89, 72, 94, 100, 99, 86, 93, 91, 85, 105, 82, 81, 92, 85, 95, 92, 89, 87, 87, 76, 94, 101, 96, 81, 94, 90, 89, 92, 89, 91, 85, 101, 98, 101, 92, 105, 81, 91, 101, 85, 93, 87, 92, 90, 98, 86, 92, 104, 81, 110, 96, 84, 94, 77, 109, 87, 101, 93, 97, 96, 96, 68, 91, 88, 85, 98, 82, 86, 106, 114, 78, 103, 103, 87, 83, 100, 98, 73, 85, 91, 85, 82, 99, 86, 77, 93, 84, 82, 97, 106, 98, 102, 92, 105, 93, 91, 82, 107, 89, 97] 245.0 229.17 207.0 253.0 [224, 248, 235, 218, 221, 233, 218, 219, 241, 222, 251, 227, 242, 240, 228, 214, 229, 229, 231, 232, 236, 222, 227, 221, 220, 232, 227, 223, 239, 233, 228, 238, 228, 224, 217, 222, 236, 238, 218, 235, 211, 246, 232, 250, 226, 226, 225, 218, 247, 215, 235, 244, 217, 232, 207, 233, 227, 227, 235, 215, 224, 253, 232, 235, 236, 236, 221, 236, 215, 208, 248, 216, 222, 232, 234, 231, 227, 243, 250, 232, 240, 235, 225, 224, 237, 223, 229, 232, 227, 214, 223, 223, 229, 210, 235, 237, 228, 226, 227, 228] Skin-Melanoma SBS9 T>C 392.0 738.0 484.03 647.25 8.480975521515095e-05 0.000387403008765732 12.861 8786.0 Intergenic 1.883 1.337 1.408 1 1 1 218.0 240.53 206.0 270.0 [241, 241, 236, 214, 261, 255, 240, 226, 239, 238, 255, 241, 243, 243, 236, 239, 227, 227, 238, 229, 251, 230, 244, 211, 247, 258, 242, 224, 236, 246, 229, 238, 215, 238, 248, 227, 258, 251, 235, 264, 231, 223, 220, 242, 242, 240, 249, 250, 241, 234, 248, 252, 227, 263, 259, 248, 256, 268, 257, 253, 248, 232, 264, 235, 252, 249, 254, 240, 237, 241, 224, 227, 239, 270, 232, 259, 234, 244, 248, 238, 244, 218, 245, 206, 234, 247, 222, 245, 243, 215, 248, 238, 264, 230, 230, 256, 240, 221, 232, 244] 174.0 243.5 214.0 276.0 [224, 243, 243, 243, 229, 233, 265, 249, 259, 237, 261, 249, 242, 232, 218, 235, 225, 258, 260, 252, 231, 268, 263, 248, 226, 246, 248, 263, 245, 240, 243, 250, 234, 226, 247, 241, 225, 243, 238, 245, 241, 228, 244, 240, 245, 241, 232, 228, 244, 236, 254, 228, 253, 254, 253, 231, 236, 254, 224, 259, 240, 228, 240, 269, 216, 237, 232, 236, 255, 244, 249, 249, 247, 238, 256, 234, 261, 258, 238, 257, 214, 257, 248, 276, 263, 257, 246, 257, 253, 248, 252, 243, 242, 243, 234, 232, 225, 231, 241, 252] 738.0 647.25 610.0 684.0 [670, 648, 650, 680, 637, 644, 626, 658, 634, 659, 615, 640, 644, 656, 673, 661, 680, 646, 631, 650, 645, 632, 631, 673, 654, 624, 644, 643, 651, 644, 656, 642, 681, 666, 638, 661, 649, 639, 658, 622, 662, 684, 664, 650, 645, 653, 652, 655, 649, 663, 631, 653, 655, 615, 622, 653, 638, 610, 652, 620, 639, 670, 630, 626, 660, 648, 646, 659, 640, 643, 657, 659, 644, 619, 639, 641, 635, 629, 646, 636, 674, 658, 635, 648, 633, 630, 663, 629, 634, 666, 627, 649, 624, 653, 669, 646, 668, 681, 656, 635] Skin-Melanoma SBS9 T>G 1863.0 4513.0 2699.91 3695.18 4.0828134255277435e-53 5.279161844609729e-52 72.57 8786.0 Intergenic 2.422 1.369 1.77 1 1 1 1 1 826.0 1274.37 1202.0 1349.0 [1299, 1328, 1279, 1300, 1269, 1299, 1276, 1294, 1271, 1335, 1232, 1259, 1308, 1305, 1342, 1259, 1282, 1300, 1250, 1276, 1243, 1225, 1291, 1245, 1317, 1211, 1271, 1275, 1225, 1268, 1269, 1264, 1305, 1246, 1253, 1349, 1225, 1330, 1287, 1258, 1243, 1270, 1300, 1236, 1225, 1202, 1280, 1269, 1343, 1277, 1260, 1265, 1285, 1349, 1256, 1319, 1320, 1283, 1218, 1239, 1289, 1257, 1269, 1266, 1273, 1272, 1203, 1217, 1286, 1227, 1252, 1304, 1280, 1244, 1258, 1260, 1248, 1271, 1275, 1285, 1238, 1288, 1317, 1323, 1288, 1273, 1259, 1278, 1302, 1328, 1213, 1290, 1229, 1262, 1255, 1291, 1308, 1339, 1217, 1344] 1037.0 1425.54 1347.0 1529.0 [1411, 1405, 1461, 1400, 1353, 1456, 1388, 1441, 1503, 1347, 1479, 1421, 1406, 1417, 1407, 1446, 1464, 1410, 1421, 1445, 1435, 1439, 1403, 1354, 1412, 1443, 1427, 1430, 1529, 1443, 1409, 1457, 1359, 1464, 1417, 1393, 1442, 1423, 1405, 1427, 1417, 1475, 1363, 1434, 1464, 1427, 1463, 1427, 1393, 1445, 1460, 1435, 1372, 1399, 1375, 1415, 1421, 1413, 1421, 1352, 1430, 1391, 1421, 1435, 1430, 1451, 1450, 1417, 1393, 1425, 1482, 1391, 1451, 1438, 1429, 1477, 1384, 1472, 1411, 1421, 1435, 1424, 1445, 1392, 1419, 1439, 1407, 1478, 1480, 1391, 1432, 1393, 1465, 1449, 1447, 1427, 1420, 1425, 1446, 1378] 4513.0 3695.18 3613.0 3804.0 [3684, 3661, 3664, 3691, 3771, 3638, 3735, 3662, 3620, 3713, 3685, 3709, 3685, 3675, 3643, 3688, 3647, 3689, 3721, 3666, 3729, 3723, 3695, 3791, 3667, 3739, 3688, 3692, 3653, 3681, 3723, 3681, 3731, 3686, 3722, 3653, 3727, 3643, 3699, 3705, 3733, 3663, 3731, 3723, 3704, 3761, 3646, 3703, 3655, 3679, 3676, 3698, 3739, 3655, 3765, 3663, 3655, 3700, 3747, 3804, 3673, 3749, 3705, 3701, 3690, 3669, 3755, 3765, 3723, 3743, 3661, 3694, 3671, 3711, 3713, 3658, 3764, 3647, 3712, 3688, 3717, 3691, 3632, 3677, 3695, 3679, 3728, 3649, 3613, 3675, 3748, 3712, 3693, 3682, 3689, 3681, 3661, 3635, 3723, 3671] Summary across all cancer types signature mutation_type strand fold_change_1.1 len(fold_change_1.1_cancer_types) fold_change_1.2 len(fold_change_1.2_cancer_types) fold_change_1.3 len(fold_change_1.3_cancer_types) fold_change_1.5 len(fold_change_1.5_cancer_types) fold_change_1.75 len(fold_change_1.75_cancer_types) fold_change_2+ len(fold_change_2+_cancer_types) all_cancer_types_list len(all_cancer_types_list) avg_fold_change SBS9 C>A Intergenic ['Lymph-BNHL'] 1 ['Lymph-BNHL'] 1 ['Lymph-BNHL'] 1 ['Lymph-BNHL'] 1 ['Lymph-BNHL'] 1 [] 0 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 1.75 SBS9 T>A Intergenic ['Lymph-BNHL', 'Lymph-CLL'] 2 ['Lymph-BNHL', 'Lymph-CLL'] 2 ['Lymph-BNHL', 'Lymph-CLL'] 2 ['Lymph-CLL'] 1 [] 0 [] 0 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 1.4 SBS9 T>C Intergenic ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 [] 0 [] 0 [] 0 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 1.3 SBS9 T>G Intergenic ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 ['Lymph-CLL', 'Skin-Melanoma'] 2 [] 0 ['Lymph-BNHL', 'Lymph-CLL', 'Skin-Melanoma'] 3 1.6666666666666667