# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	cutoff	number_of_mutations	average_probability	file_name	pearson_corr	pearson_p_value	pearson_q_value	real_average_number_of_overlaps	sims_average_number_of_overlaps	avg_real_signal	sim_data_avg_signal	fold_change	real_average_signal_array	sims_average_signal_array
SBS9	Lymph-BNHL	0.52	165179	0.757	SBS9_ENCFF449NOT_B-cell_Normal_CTCF-human_AverageSignalArray.txt	0.202	1.0906600459928741e-10		545.94	829.584	182.267	185.0	0.985	[167.988, 167.946, 167.946, 167.622, 166.955, 166.934, 166.964, 166.754, 167.026, 167.026, 167.33, 167.219, 166.785, 166.493, 166.394, 167.608, 168.513, 168.964, 169.231, 169.84, 169.336, 170.573, 171.126, 171.291, 171.004, 171.378, 171.971, 172.079, 171.834, 172.053, 172.17, 171.386, 171.205, 171.278, 171.001, 171.92, 172.355, 172.149, 171.798, 172.052, 171.166, 171.166, 171.617, 171.617, 171.686, 171.148, 171.819, 172.068, 172.27, 172.461, 172.306, 172.009, 172.021, 171.968, 171.799, 172.058, 171.463, 171.29, 171.625, 171.629, 171.11, 171.152, 171.16, 170.847, 171.082, 170.865, 171.716, 171.437, 171.437, 171.449, 170.407, 170.726, 170.476, 170.248, 170.514, 169.447, 169.828, 169.319, 169.315, 169.611, 170.077, 169.719, 168.914, 168.654, 168.471, 169.473, 170.007, 169.498, 169.68, 170.319, 169.768, 169.768, 169.768, 169.768, 169.715, 169.274, 169.274, 170.227, 170.186, 169.899, 169.141, 167.997, 166.977, 167.221, 166.492, 166.757, 166.913, 167.381, 167.939, 168.357, 168.14, 167.847, 166.542, 166.351, 166.746, 166.902, 166.674, 166.922, 167.693, 167.572, 167.579, 168.314, 167.868, 168.464, 169.19, 169.474, 169.646, 170.674, 170.982, 170.982, 170.982, 171.237, 171.595, 171.877, 171.728, 171.889, 172.638, 172.608, 172.948, 172.381, 172.381, 172.427, 172.662, 172.683, 172.568, 172.431, 173.556, 174.023, 173.125, 172.38, 172.98, 172.907, 172.86, 173.576, 173.724, 175.061, 175.269, 175.266, 174.085, 174.045, 174.057, 173.691, 173.342, 173.09, 174.169, 173.577, 174.342, 174.504, 174.691, 174.033, 174.158, 173.964, 173.705, 173.562, 172.436, 172.209, 172.07, 171.791, 172.303, 172.292, 172.601, 172.298, 171.835, 171.238, 171.749, 171.502, 172.602, 172.201, 172.182, 172.508, 173.014, 172.728, 173.642, 174.228, 173.469, 173.274, 173.222, 172.045, 172.942, 173.232, 174.201, 174.638, 174.435, 175.518, 175.769, 176.057, 176.098, 176.15, 175.794, 175.794, 175.648, 175.139, 174.122, 174.122, 174.329, 174.966, 175.485, 176.132, 176.699, 177.261, 177.233, 176.539, 178.274, 177.884, 178.155, 177.989, 177.926, 176.97, 176.561, 176.357, 177.831, 177.544, 177.35, 177.031, 178.276, 178.122, 178.436, 178.36, 178.731, 178.642, 179.732, 180.411, 179.781, 180.242, 179.638, 178.956, 179.087, 179.392, 179.403, 180.23, 180.385, 180.042, 179.944, 179.109, 179.174, 177.778, 178.422, 177.932, 176.26, 177.275, 177.007, 177.53, 177.535, 177.723, 177.607, 177.171, 177.508, 177.299, 177.736, 177.714, 177.447, 177.163, 176.753, 176.019, 176.637, 176.561, 175.778, 175.657, 175.82, 176.348, 177.758, 177.784, 177.666, 177.663, 176.847, 177.175, 177.178, 175.842, 175.587, 176.132, 176.856, 177.426, 176.957, 176.006, 176.273, 176.211, 176.305, 176.86, 176.678, 177.217, 177.217, 176.495, 177.074, 177.266, 177.14, 176.954, 176.423, 175.921, 174.846, 174.098, 174.286, 174.267, 173.902, 173.497, 173.65, 174.727, 174.491, 173.859, 175.154, 175.384, 175.349, 175.633, 175.192, 175.192, 175.909, 176.121, 175.335, 175.986, 175.447, 175.447, 176.0, 175.587, 175.642, 175.642, 175.659, 176.181, 176.478, 177.622, 177.507, 177.362, 176.858, 177.022, 177.253, 178.059, 178.261, 178.153, 178.294, 178.949, 179.388, 179.801, 179.697, 179.721, 179.949, 179.267, 178.653, 178.43, 178.016, 178.255, 179.722, 180.506, 179.46, 180.164, 180.049, 180.033, 179.682, 179.972, 180.483, 180.973, 181.324, 181.6, 182.489, 182.497, 182.391, 182.843, 183.018, 182.758, 182.608, 182.499, 182.258, 182.2, 183.039, 183.039, 183.079, 182.799, 182.229, 182.368, 182.553, 182.632, 182.632, 182.885, 183.486, 182.15, 182.208, 182.352, 182.42, 182.374, 182.112, 182.244, 182.035, 182.035, 182.461, 182.331, 181.639, 181.367, 181.868, 182.145, 181.818, 181.815, 182.152, 182.083, 181.715, 181.573, 181.571, 180.965, 180.739, 179.667, 180.23, 180.561, 180.064, 181.755, 182.055, 181.649, 182.184, 181.725, 181.674, 181.674, 181.943, 181.871, 182.347, 184.044, 183.778, 183.273, 183.051, 183.397, 184.222, 183.676, 184.182, 183.575, 183.601, 183.775, 183.556, 183.049, 183.395, 182.72, 182.356, 181.921, 182.577, 182.134, 182.065, 181.817, 181.459, 181.997, 182.173, 182.226, 182.226, 182.249, 182.577, 181.423, 180.906, 180.543, 180.898, 180.798, 180.933, 181.743, 182.06, 181.1, 180.018, 179.913, 179.274, 178.732, 178.826, 179.371, 179.768, 179.874, 180.424, 180.271, 180.376, 180.331, 180.102, 180.102, 179.898, 179.912, 180.197, 180.802, 180.806, 180.806, 180.574, 181.035, 180.827, 180.524, 180.22, 180.22, 180.983, 181.253, 181.253, 181.593, 181.295, 182.102, 182.172, 182.041, 182.589, 182.128, 182.255, 182.293, 181.96, 182.139, 181.474, 181.518, 182.1, 181.746, 182.526, 182.566, 182.563, 184.268, 184.27, 183.624, 184.302, 183.784, 183.42, 183.104, 183.468, 183.355, 183.223, 183.458, 183.316, 183.653, 183.653, 183.649, 183.679, 183.041, 183.013, 182.682, 183.723, 184.191, 184.176, 184.176, 185.12, 185.142, 184.95, 185.224, 185.224, 184.786, 185.346, 185.84, 186.369, 185.876, 185.236, 185.153, 185.167, 185.001, 184.783, 185.852, 186.598, 186.071, 185.93, 185.321, 185.321, 185.594, 185.907, 186.189, 186.319, 186.237, 186.487, 186.22, 185.894, 186.207, 186.487, 185.562, 185.416, 184.917, 184.461, 184.594, 184.479, 184.65, 184.647, 184.126, 184.253, 185.154, 184.838, 184.563, 183.853, 182.79, 183.165, 182.785, 182.996, 183.544, 183.552, 182.515, 182.506, 182.442, 182.244, 182.343, 182.507, 182.459, 182.673, 182.776, 181.833, 181.423, 181.564, 181.282, 181.282, 181.544, 181.189, 181.076, 181.293, 181.293, 180.497, 180.561, 181.051, 180.716, 180.958, 180.647, 180.37, 180.37, 180.569, 180.766, 180.788, 181.099, 180.692, 180.645, 181.059, 180.604, 179.995, 179.025, 179.245, 179.442, 179.94, 179.703, 179.657, 179.652, 179.282, 178.212, 177.943, 177.693, 177.549, 176.876, 177.197, 176.819, 176.661, 175.784, 175.784, 175.891, 175.944, 175.521, 175.571, 175.072, 174.697, 174.464, 174.633, 174.131, 174.593, 174.754, 174.863, 173.661, 173.253, 173.442, 173.663, 174.607, 175.423, 175.423, 175.262, 175.706, 175.706, 174.995, 175.193, 174.98, 174.898, 175.435, 174.964, 175.238, 175.04, 174.762, 174.969, 175.45, 175.311, 174.939, 173.629, 173.695, 173.727, 173.684, 173.809, 173.564, 174.007, 174.376, 174.521, 174.569, 174.546, 174.22, 174.156, 173.828, 173.837, 174.385, 174.033, 174.103, 173.647, 173.231, 173.214, 173.214, 171.983, 172.069, 171.977, 171.639, 172.155, 172.285, 173.408, 172.777, 173.457, 174.133, 174.216, 174.258, 174.517, 174.241, 174.271, 174.763, 174.901, 175.097, 174.355, 173.885, 173.943, 172.553, 172.651, 172.442, 171.967, 172.351, 172.541, 172.565, 172.493, 173.072, 173.851, 174.302, 174.302, 173.773, 172.796, 173.16, 172.56, 172.45, 171.659, 171.162, 170.994, 170.85, 171.005, 171.43, 171.409, 171.466, 170.796, 171.399, 171.303, 169.84, 169.694, 168.855, 168.855, 168.313, 168.577, 167.974, 169.057, 168.996, 168.324, 168.535, 168.271, 168.674, 168.643, 168.536, 168.564, 168.87, 168.281, 167.839, 167.809, 166.953, 167.439, 167.254, 167.748, 167.939, 167.857, 167.394, 166.861, 166.608, 166.049, 164.889, 164.889, 165.254, 165.04, 164.805, 164.535, 164.571, 164.075, 164.489, 164.446, 164.54, 164.675, 164.494, 164.481, 163.792, 163.759, 163.302, 163.393, 162.771, 162.501, 162.344, 162.372, 161.838, 161.466, 162.166, 161.548, 161.121, 161.256, 161.443, 161.21, 161.246, 161.37, 161.233, 162.132, 162.382, 161.807, 161.736, 161.54, 161.077, 161.057, 161.193, 160.282, 160.19, 158.031, 158.031, 157.798, 157.756, 157.408, 156.193, 156.345, 155.099, 155.112, 155.147, 155.189, 154.618, 154.504, 154.048, 153.972, 154.126, 153.801, 153.801, 153.36, 153.343, 153.875, 153.692, 153.499, 153.499, 153.658, 153.921, 153.647, 153.647, 153.492, 154.036, 153.235, 153.622, 153.157, 152.906, 152.688, 153.289, 152.994, 153.135, 154.858, 155.124, 155.363, 155.814, 155.387, 154.863, 155.007, 154.965, 154.894, 154.893, 154.788, 155.069, 155.037, 155.255, 155.523, 155.523, 155.378, 155.378, 154.738, 154.7, 153.93, 154.348, 154.427, 154.819, 154.274, 154.101, 154.34, 154.384, 154.384, 154.156, 153.743, 153.035, 153.021, 152.789, 152.66, 152.533, 152.385, 151.837, 151.882, 151.89, 151.775, 152.231, 152.095, 151.916, 152.456, 152.679, 152.535, 152.552, 152.012, 152.62, 153.247, 154.532, 154.193, 154.948, 154.663, 154.126, 154.362, 154.574, 155.599, 155.265, 155.954, 155.759, 155.859, 156.435, 156.001, 156.478, 156.504, 156.067, 156.978, 156.975, 156.652, 156.943, 156.828, 156.948, 156.332, 156.538, 156.505, 156.437, 155.837, 156.053, 156.025, 156.117, 156.248, 155.413, 154.664, 154.768, 154.022, 154.12, 154.149, 154.149, 154.174, 153.988, 153.389, 153.777, 154.004, 153.338, 153.512, 153.745, 153.225, 153.965, 153.667, 153.966, 155.034, 155.979, 156.443, 156.624, 156.772, 157.202, 156.964, 156.632, 156.66, 156.709, 156.46, 156.614, 156.576, 156.195, 156.766, 157.715, 157.236, 156.065, 155.873, 155.434, 155.476, 156.067, 156.156, 156.037, 155.491, 156.083, 155.239, 155.138, 154.854, 154.74, 154.678, 154.182, 154.691, 154.887, 154.857, 154.591, 153.748, 154.041, 153.439, 152.11, 152.112]	[182.999, 183.012, 182.985, 183.007, 183.054, 182.959, 182.909, 182.952, 182.978, 182.911, 182.907, 182.908, 182.925, 182.897, 182.922, 182.992, 182.951, 182.975, 182.987, 182.95, 182.966, 182.949, 183.016, 183.039, 182.998, 183.042, 183.159, 183.208, 183.315, 183.346, 183.301, 183.356, 183.271, 183.244, 183.309, 183.362, 183.375, 183.401, 183.401, 183.473, 183.53, 183.554, 183.586, 183.617, 183.68, 183.725, 183.686, 183.714, 183.695, 183.712, 183.716, 183.707, 183.717, 183.681, 183.651, 183.656, 183.704, 183.733, 183.782, 183.724, 183.734, 183.739, 183.755, 183.711, 183.682, 183.664, 183.647, 183.627, 183.576, 183.645, 183.609, 183.615, 183.64, 183.729, 183.778, 183.749, 183.761, 183.759, 183.756, 183.769, 183.814, 183.766, 183.715, 183.806, 183.763, 183.765, 183.806, 183.863, 183.852, 183.858, 183.917, 183.988, 183.96, 183.919, 183.897, 183.914, 183.895, 183.941, 183.94, 183.97, 183.94, 184.008, 184.041, 184.001, 183.987, 184.0, 184.039, 184.122, 184.106, 184.112, 184.132, 184.168, 184.149, 184.25, 184.231, 184.246, 184.298, 184.322, 184.285, 184.272, 184.307, 184.333, 184.305, 184.33, 184.323, 184.314, 184.414, 184.4, 184.357, 184.366, 184.392, 184.372, 184.353, 184.427, 184.378, 184.409, 184.432, 184.421, 184.431, 184.375, 184.392, 184.351, 184.377, 184.367, 184.454, 184.416, 184.405, 184.423, 184.459, 184.434, 184.348, 184.357, 184.366, 184.372, 184.425, 184.438, 184.435, 184.422, 184.313, 184.315, 184.327, 184.32, 184.362, 184.435, 184.436, 184.463, 184.403, 184.325, 184.326, 184.303, 184.335, 184.32, 184.374, 184.375, 184.292, 184.358, 184.42, 184.46, 184.427, 184.401, 184.457, 184.407, 184.427, 184.437, 184.357, 184.334, 184.359, 184.321, 184.341, 184.33, 184.445, 184.369, 184.411, 184.453, 184.544, 184.482, 184.447, 184.458, 184.418, 184.352, 184.364, 184.388, 184.37, 184.367, 184.357, 184.408, 184.429, 184.446, 184.518, 184.445, 184.44, 184.426, 184.42, 184.405, 184.45, 184.474, 184.475, 184.408, 184.304, 184.333, 184.322, 184.332, 184.3, 184.272, 184.265, 184.278, 184.269, 184.22, 184.211, 184.254, 184.203, 184.154, 184.162, 184.184, 184.199, 184.243, 184.238, 184.23, 184.257, 184.146, 184.098, 184.111, 184.087, 184.057, 184.072, 184.069, 184.097, 184.109, 184.13, 184.076, 184.024, 184.047, 183.982, 184.065, 184.078, 184.073, 184.096, 184.053, 184.098, 184.018, 184.006, 184.011, 184.058, 184.092, 184.062, 184.134, 184.135, 184.153, 184.125, 184.181, 184.143, 184.154, 184.122, 184.126, 184.099, 184.058, 184.046, 184.079, 184.08, 184.016, 184.016, 184.042, 184.045, 183.962, 183.91, 183.906, 183.843, 183.828, 183.908, 183.891, 183.951, 183.922, 183.902, 183.896, 183.919, 183.94, 183.979, 184.069, 184.077, 184.053, 184.01, 184.068, 184.043, 184.01, 183.994, 184.055, 184.1, 184.107, 184.075, 184.088, 184.056, 184.051, 184.07, 184.045, 184.113, 184.164, 184.261, 184.266, 184.273, 184.308, 184.279, 184.343, 184.396, 184.364, 184.379, 184.36, 184.378, 184.443, 184.454, 184.481, 184.459, 184.446, 184.421, 184.448, 184.426, 184.437, 184.385, 184.435, 184.398, 184.411, 184.391, 184.437, 184.374, 184.392, 184.367, 184.336, 184.376, 184.348, 184.395, 184.341, 184.364, 184.379, 184.399, 184.383, 184.392, 184.395, 184.448, 184.423, 184.467, 184.368, 184.39, 184.439, 184.532, 184.533, 184.525, 184.521, 184.521, 184.5, 184.477, 184.441, 184.398, 184.416, 184.482, 184.468, 184.47, 184.481, 184.542, 184.474, 184.512, 184.543, 184.557, 184.583, 184.519, 184.527, 184.53, 184.532, 184.541, 184.574, 184.612, 184.588, 184.626, 184.562, 184.553, 184.527, 184.506, 184.474, 184.532, 184.583, 184.551, 184.584, 184.553, 184.573, 184.569, 184.567, 184.684, 184.621, 184.636, 184.665, 184.72, 184.674, 184.649, 184.67, 184.714, 184.678, 184.636, 184.628, 184.55, 184.561, 184.576, 184.537, 184.524, 184.467, 184.465, 184.464, 184.509, 184.502, 184.567, 184.67, 184.664, 184.728, 184.653, 184.69, 184.677, 184.706, 184.669, 184.603, 184.57, 184.605, 184.675, 184.718, 184.766, 184.757, 184.77, 184.821, 184.877, 184.907, 184.995, 184.957, 184.985, 184.921, 184.987, 185.066, 185.021, 184.985, 184.913, 184.965, 185.039, 185.171, 185.197, 185.231, 185.281, 185.349, 185.37, 185.3, 185.212, 185.166, 185.14, 185.135, 185.129, 185.085, 185.1, 185.07, 185.016, 185.079, 185.052, 185.16, 185.165, 185.201, 185.316, 185.29, 185.3, 185.25, 185.286, 185.251, 185.259, 185.314, 185.377, 185.328, 185.315, 185.277, 185.277, 185.26, 185.224, 185.141, 185.047, 185.081, 185.043, 185.07, 184.981, 184.934, 184.962, 184.98, 184.933, 184.974, 184.955, 184.936, 184.925, 184.867, 184.901, 184.829, 184.826, 184.841, 184.829, 184.88, 184.865, 184.841, 184.863, 184.838, 184.73, 184.697, 184.705, 184.758, 184.815, 184.801, 184.834, 184.849, 184.908, 184.843, 184.838, 184.811, 184.837, 184.839, 184.817, 184.895, 184.862, 184.911, 184.851, 184.75, 184.794, 184.796, 184.84, 184.796, 184.796, 184.757, 184.774, 184.761, 184.769, 184.831, 184.736, 184.755, 184.754, 184.679, 184.661, 184.651, 184.636, 184.533, 184.662, 184.581, 184.514, 184.444, 184.479, 184.42, 184.446, 184.459, 184.416, 184.407, 184.438, 184.438, 184.488, 184.475, 184.503, 184.53, 184.588, 184.638, 184.636, 184.584, 184.536, 184.535, 184.549, 184.567, 184.537, 184.497, 184.495, 184.436, 184.376, 184.423, 184.445, 184.489, 184.475, 184.407, 184.335, 184.298, 184.292, 184.278, 184.237, 184.183, 184.164, 184.188, 184.171, 184.191, 184.205, 184.215, 184.185, 184.135, 184.139, 184.185, 184.166, 184.189, 184.232, 184.234, 184.252, 184.25, 184.25, 184.248, 184.269, 184.334, 184.286, 184.271, 184.292, 184.369, 184.34, 184.303, 184.32, 184.243, 184.252, 184.223, 184.189, 184.19, 184.193, 184.176, 184.152, 184.188, 184.219, 184.273, 184.308, 184.263, 184.22, 184.21, 184.223, 184.137, 184.125, 184.157, 184.19, 184.2, 184.125, 184.155, 184.113, 184.195, 184.129, 184.158, 184.142, 184.134, 184.158, 184.149, 184.197, 184.17, 184.131, 184.093, 184.108, 184.069, 184.176, 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