# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. # For real mutations on lagging:A and leading:E strands averaged across cancer types. MutationType Across_All_Cancer_Types A:A[C>A]A 645.247 E:A[C>A]A 682.209 A:A[C>G]A 76.404 E:A[C>G]A 77.455 A:A[C>T]A 97.983 E:A[C>T]A 98.895 A:A[T>A]A 304.35 E:A[T>A]A 319.659 A:A[T>C]A 114.83 E:A[T>C]A 117.94 A:A[T>G]A 38.311 E:A[T>G]A 39.129 A:A[C>A]C 550.722 E:A[C>A]C 590.031 A:A[C>G]C 52.346 E:A[C>G]C 53.898 A:A[C>T]C 40.774 E:A[C>T]C 42.141 A:A[T>A]C 254.038 E:A[T>A]C 265.752 A:A[T>C]C 64.065 E:A[T>C]C 67.592 A:A[T>G]C 9.943 E:A[T>G]C 10.101 A:A[C>A]G 75.47 E:A[C>A]G 76.881 A:A[C>G]G 6.966 E:A[C>G]G 7.45 A:A[C>T]G 49.965 E:A[C>T]G 49.856 A:A[T>A]G 293.294 E:A[T>A]G 286.123 A:A[T>C]G 66.42 E:A[T>C]G 66.399 A:A[T>G]G 60.281 E:A[T>G]G 56.771 A:A[C>A]T 610.362 E:A[C>A]T 647.449 A:A[C>G]T 98.104 E:A[C>G]T 93.16 A:A[C>T]T 179.108 E:A[C>T]T 182.879 A:A[T>A]T 453.212 E:A[T>A]T 472.097 A:A[T>C]T 166.945 E:A[T>C]T 164.173 A:A[T>G]T 17.281 E:A[T>G]T 16.182 A:C[C>A]A 625.476 E:C[C>A]A 665.245 A:C[C>G]A 72.186 E:C[C>G]A 72.35 A:C[C>T]A 49.959 E:C[C>T]A 49.827 A:C[T>A]A 279.493 E:C[T>A]A 291.342 A:C[T>C]A 34.958 E:C[T>C]A 36.264 A:C[T>G]A 25.186 E:C[T>G]A 25.963 A:C[C>A]C 466.619 E:C[C>A]C 491.894 A:C[C>G]C 57.957 E:C[C>G]C 60.715 A:C[C>T]C 66.615 E:C[C>T]C 67.146 A:C[T>A]C 318.026 E:C[T>A]C 332.22 A:C[T>C]C 108.757 E:C[T>C]C 110.688 A:C[T>G]C 24.366 E:C[T>G]C 25.008 A:C[C>A]G 44.285 E:C[C>A]G 43.66 A:C[C>G]G 0.198 E:C[C>G]G 0.205 A:C[C>T]G 17.678 E:C[C>T]G 17.374 A:C[T>A]G 375.195 E:C[T>A]G 377.149 A:C[T>C]G 12.824 E:C[T>C]G 13.031 A:C[T>G]G 68.341 E:C[T>G]G 70.087 A:C[C>A]T 612.737 E:C[C>A]T 618.118 A:C[C>G]T 82.773 E:C[C>G]T 76.15 A:C[C>T]T 245.693 E:C[C>T]T 239.111 A:C[T>A]T 594.876 E:C[T>A]T 585.197 A:C[T>C]T 101.519 E:C[T>C]T 97.939 A:C[T>G]T 14.284 E:C[T>G]T 13.85 A:G[C>A]A 411.401 E:G[C>A]A 428.456 A:G[C>G]A 40.866 E:G[C>G]A 41.44 A:G[C>T]A 5.057 E:G[C>T]A 4.969 A:G[T>A]A 164.696 E:G[T>A]A 169.215 A:G[T>C]A 45.085 E:G[T>C]A 44.62 A:G[T>G]A 20.723 E:G[T>G]A 21.587 A:G[C>A]C 294.264 E:G[C>A]C 301.989 A:G[C>G]C 36.728 E:G[C>G]C 37.446 A:G[C>T]C 4.083 E:G[C>T]C 3.999 A:G[T>A]C 157.368 E:G[T>A]C 156.273 A:G[T>C]C 44.498 E:G[T>C]C 45.349 A:G[T>G]C 10.423 E:G[T>G]C 10.314 A:G[C>A]G 37.003 E:G[C>A]G 37.139 A:G[C>G]G 6.815 E:G[C>G]G 6.536 A:G[C>T]G 29.024 E:G[C>T]G 29.057 A:G[T>A]G 183.383 E:G[T>A]G 181.558 A:G[T>C]G 35.956 E:G[T>C]G 33.948 A:G[T>G]G 58.804 E:G[T>G]G 56.696 A:G[C>A]T 399.99 E:G[C>A]T 399.471 A:G[C>G]T 71.816 E:G[C>G]T 64.451 A:G[C>T]T 81.594 E:G[C>T]T 79.15 A:G[T>A]T 336.253 E:G[T>A]T 331.695 A:G[T>C]T 109.379 E:G[T>C]T 104.534 A:G[T>G]T 36.73 E:G[T>G]T 35.984 A:T[C>A]A 424.333 E:T[C>A]A 417.57 A:T[C>G]A 22.811 E:T[C>G]A 21.124 A:T[C>T]A 83.364 E:T[C>T]A 78.695 A:T[T>A]A 240.408 E:T[T>A]A 242.116 A:T[T>C]A 34.986 E:T[T>C]A 34.374 A:T[T>G]A 0.0 E:T[T>G]A 0.0 A:T[C>A]C 353.938 E:T[C>A]C 351.511 A:T[C>G]C 20.617 E:T[C>G]C 19.372 A:T[C>T]C 4.505 E:T[C>T]C 4.219 A:T[T>A]C 236.375 E:T[T>A]C 239.21 A:T[T>C]C 54.123 E:T[T>C]C 51.519 A:T[T>G]C 12.815 E:T[T>G]C 13.32 A:T[C>A]G 24.776 E:T[C>A]G 24.248 A:T[C>G]G 1.172 E:T[C>G]G 1.111 A:T[C>T]G 0.569 E:T[C>T]G 0.548 A:T[T>A]G 175.717 E:T[T>A]G 171.643 A:T[T>C]G 0.0 E:T[T>C]G 0.0 A:T[T>G]G 53.569 E:T[T>G]G 53.375 A:T[C>A]T 605.207 E:T[C>A]T 578.525 A:T[C>G]T 4.448 E:T[C>G]T 4.014 A:T[C>T]T 97.293 E:T[C>T]T 89.465 A:T[T>A]T 521.746 E:T[T>A]T 506.746 A:T[T>C]T 74.842 E:T[T>C]T 71.464 A:T[T>G]T 18.84 E:T[T>G]T 17.964 # There must be at least 1000 mutations on the strands. # Signature and mutation type must have at least 5% of all signature mutations on the strands. # Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1. cancer_type signature mutation_type Lagging_real_count Leading_real_count Lagging_mean_sims_count Leading_mean_sims_count lagging_versus_leading_p_value lagging_versus_leading_q_value percentage_of_mutations_on_strands signature_number_of_mutations_on_strands significant_strand FC_REAL FC_SIMS FC fold_change_1.1 fold_change_1.2 fold_change_1.3 fold_change_1.5 fold_change_1.75 fold_change_2+ Lagging_real_count.1 Lagging_mean_sims_count.1 Lagging_min_sims_count Lagging_max_sims_count Lagging_sims_count_list Leading_real_count.1 Leading_mean_sims_count.1 Leading_min_sims_count Leading_max_sims_count Leading_sims_count_list Bladder-TCC SBS8 C>A 1853.0 2050.0 1947.95 2001.38 0.10399046291209313 0.2942404159663406 49.694 7854.0 Leading 1.106 1.027 1.077 1853.0 1947.95 1859.0 2044.0 [1957, 1925, 1908, 2012, 1912, 1977, 1881, 1939, 1960, 1954, 1947, 1949, 1982, 2007, 1899, 1921, 1881, 1885, 1957, 1952, 1928, 1859, 1969, 1959, 1947, 1953, 1970, 1954, 1951, 1983, 1927, 2001, 1963, 1933, 1985, 1939, 1931, 1952, 1919, 2044, 1956, 1967, 1910, 1933, 1964, 1965, 1949, 1907, 1911, 1955, 1913, 1958, 1958, 1986, 2013, 1993, 2020, 1925, 1931, 1957, 1957, 1914, 1919, 1920, 1978, 1970, 1995, 1984, 1875, 1991, 1916, 1963, 1928, 1944, 1943, 1928, 1966, 1913, 1945, 1930, 1926, 1984, 1977, 1964, 1895, 1927, 1934, 1947, 1906, 1930, 2002, 1950, 1949, 1969, 1962, 1974, 1973, 1885, 1973, 1946] 2050.0 2001.38 1917.0 2092.0 [1987, 2008, 2024, 1955, 2033, 1968, 2068, 2044, 1987, 1998, 2007, 2011, 1948, 1940, 2045, 2027, 2013, 2057, 1965, 2004, 2048, 2092, 1961, 1982, 2002, 2000, 1962, 2019, 1961, 1947, 2028, 1960, 2006, 2037, 1963, 2007, 2020, 1999, 2001, 1917, 1989, 1980, 2034, 2034, 1985, 1991, 2008, 2018, 2066, 1989, 2042, 2007, 1992, 1948, 1963, 1956, 1933, 2027, 2043, 1990, 2006, 2062, 2029, 2033, 1980, 1967, 1981, 1982, 2058, 1972, 2025, 1968, 2007, 2011, 1972, 2020, 1970, 2035, 2037, 2006, 2011, 1982, 1951, 1985, 2052, 2047, 2010, 2010, 2046, 2025, 1938, 1989, 2012, 1987, 1987, 2001, 1949, 2033, 1975, 2031] Bladder-TCC SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7854.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Bladder-TCC SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7854.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Bladder-TCC SBS8 T>A 1960.0 1991.0 2036.21 1987.78 0.3823790020334816 0.7886959485271721 50.306 7854.0 Leading 1.016 0.976 1.041 1960.0 2036.21 1952.0 2107.0 [2073, 2034, 2054, 2073, 1986, 2086, 1991, 2023, 2028, 1995, 2056, 2017, 2052, 2074, 2034, 1986, 2064, 2025, 2085, 2039, 2040, 2039, 2076, 2016, 2006, 2086, 2057, 2018, 1994, 2057, 2050, 2018, 1986, 2050, 2021, 1952, 2027, 2037, 1997, 2054, 2069, 2023, 2040, 2038, 2002, 2033, 2027, 2034, 2009, 2050, 2039, 2030, 2037, 2019, 2039, 2037, 2079, 2027, 2107, 2103, 2020, 2050, 2027, 2061, 2062, 2019, 2035, 2011, 2028, 2007, 2025, 2029, 1990, 2001, 2047, 2087, 2059, 2058, 2011, 2059, 2068, 2012, 1997, 2062, 2040, 2063, 2044, 1992, 2011, 2067, 2026, 2017, 2009, 1999, 2045, 2035, 2068, 2037, 2053, 2092] 1991.0 1987.78 1925.0 2080.0 [1954, 1969, 1983, 1947, 2043, 1951, 2011, 1998, 1978, 2027, 1956, 2026, 1965, 1931, 2013, 2053, 1995, 1990, 1931, 1976, 1966, 1986, 1967, 2007, 2011, 1971, 1975, 2031, 2025, 1971, 1972, 2029, 2057, 1954, 2015, 2080, 1963, 1981, 1999, 1944, 1953, 2010, 2003, 1978, 2010, 1990, 2013, 2005, 2026, 1980, 1955, 2000, 1977, 1982, 1962, 1966, 1944, 2021, 1945, 1949, 2005, 1987, 1963, 1970, 1967, 1983, 1995, 2006, 1974, 2007, 1969, 2024, 2023, 2047, 1964, 1943, 1994, 1977, 2039, 1967, 1983, 2011, 2015, 1953, 1961, 1964, 2010, 2013, 2028, 1966, 1996, 1997, 1992, 2015, 1960, 1980, 1927, 2011, 1997, 1925] Bladder-TCC SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7854.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Bladder-TCC SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7854.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Breast-Cancer SBS8 C>A 7109.0 7317.0 7158.8 7312.02 0.7507261830393405 1.0 57.79 24963.0 Leading 1.029 1.021 1.008 7109.0 7158.8 7028.0 7268.0 [7125, 7244, 7172, 7071, 7179, 7182, 7184, 7032, 7218, 7230, 7214, 7165, 7235, 7124, 7091, 7083, 7174, 7115, 7156, 7103, 7209, 7185, 7123, 7186, 7254, 7195, 7045, 7163, 7260, 7080, 7202, 7092, 7192, 7123, 7147, 7236, 7199, 7106, 7261, 7105, 7213, 7268, 7261, 7163, 7213, 7224, 7140, 7200, 7128, 7175, 7181, 7190, 7139, 7219, 7096, 7263, 7115, 7174, 7181, 7128, 7064, 7189, 7171, 7120, 7098, 7215, 7226, 7119, 7079, 7106, 7175, 7140, 7123, 7145, 7170, 7224, 7254, 7042, 7104, 7109, 7143, 7168, 7178, 7134, 7099, 7128, 7202, 7104, 7028, 7143, 7042, 7153, 7172, 7186, 7082, 7171, 7175, 7207, 7207, 7154] 7317.0 7312.02 7179.0 7461.0 [7329, 7193, 7243, 7376, 7291, 7283, 7287, 7433, 7270, 7253, 7250, 7279, 7216, 7350, 7366, 7373, 7279, 7349, 7335, 7347, 7270, 7323, 7406, 7362, 7265, 7218, 7461, 7283, 7253, 7404, 7311, 7376, 7282, 7355, 7350, 7263, 7297, 7376, 7322, 7413, 7310, 7249, 7201, 7262, 7230, 7254, 7417, 7288, 7393, 7330, 7279, 7211, 7353, 7320, 7389, 7269, 7389, 7277, 7269, 7383, 7414, 7250, 7259, 7311, 7337, 7237, 7255, 7333, 7461, 7366, 7257, 7296, 7342, 7279, 7265, 7179, 7267, 7395, 7329, 7324, 7307, 7305, 7213, 7278, 7383, 7336, 7299, 7391, 7449, 7338, 7424, 7295, 7346, 7237, 7383, 7259, 7198, 7286, 7264, 7290] Breast-Cancer SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 24963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Breast-Cancer SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 24963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Breast-Cancer SBS8 T>A 5177.0 5360.0 5366.27 5249.83 0.03914636589152365 0.12582283303188532 42.21 24963.0 Leading 1.035 0.978 1.058 5177.0 5366.27 5222.0 5490.0 [5295, 5294, 5359, 5237, 5405, 5378, 5398, 5346, 5415, 5363, 5380, 5309, 5358, 5345, 5388, 5293, 5335, 5451, 5365, 5422, 5401, 5379, 5375, 5372, 5301, 5413, 5327, 5382, 5396, 5222, 5382, 5311, 5393, 5477, 5377, 5416, 5276, 5479, 5390, 5414, 5338, 5319, 5340, 5274, 5358, 5397, 5344, 5258, 5405, 5404, 5348, 5438, 5414, 5316, 5381, 5352, 5315, 5249, 5330, 5335, 5287, 5335, 5417, 5283, 5423, 5388, 5474, 5315, 5341, 5368, 5367, 5440, 5409, 5360, 5305, 5329, 5419, 5283, 5490, 5358, 5466, 5388, 5409, 5406, 5348, 5348, 5360, 5424, 5343, 5461, 5362, 5326, 5336, 5323, 5359, 5472, 5366, 5448, 5390, 5367] 5360.0 5249.83 5134.0 5372.0 [5290, 5294, 5236, 5368, 5196, 5284, 5246, 5282, 5235, 5248, 5246, 5245, 5266, 5304, 5304, 5345, 5240, 5179, 5197, 5208, 5183, 5270, 5243, 5248, 5260, 5207, 5242, 5199, 5237, 5356, 5226, 5278, 5215, 5161, 5210, 5197, 5336, 5242, 5267, 5237, 5299, 5293, 5331, 5355, 5233, 5266, 5269, 5372, 5163, 5220, 5253, 5176, 5178, 5275, 5249, 5219, 5337, 5353, 5295, 5229, 5297, 5311, 5182, 5294, 5237, 5230, 5134, 5329, 5293, 5236, 5243, 5139, 5253, 5284, 5315, 5312, 5186, 5318, 5148, 5250, 5219, 5202, 5169, 5181, 5270, 5214, 5277, 5220, 5319, 5184, 5235, 5262, 5240, 5285, 5244, 5217, 5261, 5171, 5227, 5203] Breast-Cancer SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 24963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Breast-Cancer SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 24963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] CNS-Medullo SBS8 C>A 1297.0 1336.0 1307.05 1312.41 0.6588013411893185 1.0 56.979 4621.0 Leading 1.03 1.004 1.026 1297.0 1307.05 1250.0 1384.0 [1305, 1286, 1285, 1291, 1329, 1329, 1329, 1286, 1350, 1267, 1311, 1264, 1280, 1321, 1336, 1315, 1340, 1318, 1331, 1321, 1259, 1312, 1320, 1339, 1315, 1284, 1320, 1280, 1340, 1365, 1322, 1257, 1319, 1308, 1341, 1329, 1309, 1384, 1298, 1349, 1347, 1330, 1289, 1288, 1316, 1267, 1304, 1291, 1269, 1314, 1327, 1343, 1285, 1310, 1288, 1326, 1340, 1288, 1298, 1322, 1327, 1340, 1255, 1303, 1285, 1306, 1291, 1340, 1300, 1347, 1283, 1291, 1265, 1254, 1259, 1353, 1320, 1271, 1328, 1282, 1298, 1330, 1282, 1343, 1300, 1297, 1316, 1273, 1310, 1327, 1282, 1295, 1299, 1291, 1281, 1250, 1313, 1269, 1322, 1341] 1336.0 1312.41 1260.0 1376.0 [1310, 1323, 1324, 1321, 1280, 1308, 1285, 1306, 1285, 1337, 1287, 1362, 1344, 1301, 1288, 1294, 1291, 1329, 1282, 1333, 1376, 1280, 1316, 1304, 1295, 1327, 1292, 1341, 1274, 1260, 1302, 1334, 1300, 1297, 1282, 1306, 1291, 1264, 1326, 1297, 1287, 1308, 1334, 1301, 1289, 1351, 1313, 1348, 1354, 1323, 1277, 1282, 1331, 1294, 1333, 1305, 1271, 1332, 1325, 1322, 1315, 1289, 1360, 1320, 1338, 1322, 1313, 1304, 1309, 1277, 1303, 1313, 1356, 1361, 1330, 1271, 1318, 1334, 1297, 1319, 1306, 1309, 1328, 1274, 1323, 1299, 1325, 1355, 1302, 1302, 1317, 1314, 1337, 1329, 1331, 1365, 1302, 1343, 1302, 1295] CNS-Medullo SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4621.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] CNS-Medullo SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4621.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] CNS-Medullo SBS8 T>A 993.0 995.0 992.51 979.71 0.8239436314952333 1.0 43.021 4621.0 Leading 1.002 0.987 1.015 993.0 992.51 941.0 1049.0 [995, 999, 1003, 967, 1027, 1031, 991, 1008, 979, 974, 981, 980, 949, 981, 1035, 1020, 989, 989, 1017, 973, 1023, 1015, 1007, 979, 949, 1003, 1010, 967, 991, 987, 963, 1037, 995, 996, 962, 998, 1006, 1049, 1012, 987, 1021, 990, 1012, 992, 997, 1007, 982, 998, 1002, 964, 994, 994, 998, 1011, 1021, 1023, 957, 1006, 971, 968, 987, 975, 981, 999, 1001, 1013, 1021, 999, 969, 1002, 959, 973, 1020, 965, 1006, 1009, 980, 952, 1034, 996, 977, 996, 963, 1001, 941, 1013, 1011, 989, 964, 970, 1004, 989, 974, 963, 974, 1029, 960, 992, 980, 988] 995.0 979.71 925.0 1023.0 [977, 989, 977, 1009, 931, 942, 978, 976, 996, 996, 989, 993, 1021, 995, 955, 957, 991, 988, 932, 981, 954, 956, 955, 992, 984, 971, 967, 1022, 979, 966, 1023, 929, 989, 979, 1006, 973, 967, 925, 959, 975, 942, 980, 973, 1001, 972, 970, 973, 969, 954, 1002, 990, 994, 987, 955, 971, 947, 1000, 982, 1016, 1005, 978, 989, 975, 979, 975, 960, 953, 993, 994, 983, 985, 984, 974, 991, 975, 953, 1015, 1009, 957, 980, 993, 996, 1010, 976, 1016, 987, 981, 955, 1007, 1016, 953, 974, 990, 994, 986, 953, 998, 980, 995, 982] CNS-Medullo SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4621.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] CNS-Medullo SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4621.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS8 C>A 9044.0 8907.0 9012.02 9179.46 0.1121529540668691 0.3127166380236091 50.958 35227.0 Lagging 1.015 0.982 1.034 9044.0 9012.02 8864.0 9245.0 [8938, 9116, 9086, 9023, 9053, 9007, 9022, 8965, 9011, 9012, 9061, 8999, 8998, 9121, 8973, 9056, 9093, 9036, 8864, 8945, 9114, 8956, 8936, 9072, 9137, 9063, 8978, 9046, 8894, 9104, 9049, 9022, 8994, 9101, 8900, 8976, 8920, 8923, 9006, 8947, 8970, 9074, 9057, 8990, 9091, 9118, 8928, 9058, 9083, 8996, 9008, 9112, 8921, 8975, 8920, 9003, 9125, 9051, 8991, 8981, 9074, 9027, 8875, 9095, 8986, 8939, 8941, 8961, 8932, 8960, 9008, 9059, 9091, 8921, 9026, 8912, 8955, 9123, 8894, 9111, 8999, 8947, 8879, 8966, 9078, 9079, 9100, 9245, 8978, 8948, 8996, 8930, 8971, 9086, 9024, 9084, 8987, 8942, 9104, 9000] 8907.0 9179.46 8957.0 9328.0 [9234, 9122, 9110, 9177, 9109, 9209, 9230, 9257, 9151, 9094, 9068, 9166, 9251, 9076, 9198, 9145, 9114, 9187, 9312, 9247, 9097, 9248, 9268, 9138, 9096, 9130, 9219, 9178, 9291, 9023, 9113, 9177, 9162, 9151, 9281, 9177, 9307, 9192, 9159, 9269, 9192, 9159, 9155, 9202, 9082, 9125, 9244, 9162, 9097, 9181, 9186, 9081, 9308, 9222, 9238, 9206, 9153, 9210, 9128, 9281, 9087, 9191, 9328, 9081, 9191, 9275, 9212, 9200, 9258, 9200, 9203, 9144, 9099, 9267, 9159, 9268, 9212, 9124, 9304, 9046, 9163, 9285, 9319, 9187, 9061, 9163, 9101, 8957, 9194, 9203, 9142, 9292, 9254, 9114, 9147, 9106, 9126, 9295, 9088, 9155] ESCC SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 35227.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 35227.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS8 T>A 8490.0 8786.0 8887.65 8676.32 0.006706771249103925 0.024981286053435553 49.042 35227.0 Leading 1.035 0.976 1.06 8490.0 8887.65 8690.0 9051.0 [8849, 8837, 8886, 8792, 8898, 8844, 8939, 8844, 8919, 8872, 8904, 8878, 8871, 8914, 8793, 8824, 8826, 8863, 8862, 8937, 8919, 8926, 8889, 8898, 8867, 8937, 8916, 8887, 9044, 8907, 8838, 8836, 8795, 8826, 8972, 8952, 8851, 8817, 8975, 8761, 8910, 8834, 8881, 8886, 8876, 8889, 8932, 8895, 8852, 8919, 8977, 8939, 9021, 9048, 8798, 8874, 8852, 8803, 8889, 8905, 8922, 8884, 8984, 8925, 8902, 8863, 8810, 8899, 8959, 8867, 8960, 8985, 8886, 8803, 8690, 8896, 8841, 8796, 8895, 8863, 8795, 8894, 8911, 8866, 8900, 8987, 8896, 8880, 8940, 8845, 8865, 8977, 8904, 8980, 9051, 8782, 8925, 8749, 8970, 8873] 8786.0 8676.32 8534.0 8873.0 [8722, 8690, 8732, 8738, 8685, 8760, 8654, 8677, 8583, 8646, 8671, 8664, 8718, 8704, 8761, 8737, 8753, 8714, 8678, 8665, 8686, 8574, 8731, 8630, 8693, 8608, 8658, 8660, 8536, 8734, 8719, 8739, 8750, 8705, 8569, 8619, 8673, 8724, 8620, 8873, 8683, 8730, 8685, 8682, 8671, 8705, 8650, 8664, 8672, 8595, 8565, 8621, 8582, 8560, 8833, 8667, 8730, 8731, 8710, 8646, 8661, 8694, 8591, 8652, 8647, 8694, 8702, 8633, 8610, 8624, 8600, 8540, 8651, 8760, 8859, 8663, 8733, 8716, 8674, 8711, 8799, 8707, 8618, 8647, 8669, 8575, 8688, 8602, 8668, 8741, 8692, 8588, 8690, 8619, 8534, 8787, 8634, 8752, 8639, 8733] ESCC SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 35227.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 35227.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Lymph-CLL SBS8 C>A 1590.0 1644.0 1613.87 1649.95 0.8232963063965261 1.0 44.669 7240.0 Leading 1.034 1.022 1.011 1590.0 1613.87 1527.0 1689.0 [1601.0, 1556.0, 1639.0, 1625.0, 1625.0, 1584.0, 1634.0, 1583.0, 1594.0, 1666.0, 1649.0, 1646.0, 1626.0, 1623.0, 1593.0, 1671.0, 1669.0, 1597.0, 1615.0, 1627.0, 1624.0, 1594.0, 1592.0, 1689.0, 1611.0, 1597.0, 1612.0, 1625.0, 1634.0, 1562.0, 1617.0, 1608.0, 1615.0, 1608.0, 1580.0, 1528.0, 1556.0, 1591.0, 1602.0, 1574.0, 1648.0, 1650.0, 1617.0, 1602.0, 1545.0, 1606.0, 1677.0, 1609.0, 1612.0, 1581.0, 1625.0, 1612.0, 1599.0, 1632.0, 1623.0, 1642.0, 1560.0, 1638.0, 1572.0, 1638.0, 1652.0, 1582.0, 1629.0, 1606.0, 1638.0, 1614.0, 1608.0, 1617.0, 1619.0, 1632.0, 1587.0, 1621.0, 1658.0, 1620.0, 1654.0, 1601.0, 1647.0, 1580.0, 1584.0, 1642.0, 1687.0, 1599.0, 1593.0, 1618.0, 1671.0, 1660.0, 1527.0, 1593.0, 1564.0, 1634.0, 1632.0, 1584.0, 1571.0, 1593.0, 1629.0, 1633.0, 1635.0, 1618.0, 1623.0, 1602.0] 1644.0 1649.95 1576.0 1742.0 [1697.0, 1733.0, 1634.0, 1644.0, 1667.0, 1668.0, 1636.0, 1681.0, 1660.0, 1585.0, 1652.0, 1638.0, 1652.0, 1645.0, 1654.0, 1594.0, 1601.0, 1648.0, 1656.0, 1645.0, 1636.0, 1671.0, 1701.0, 1576.0, 1663.0, 1669.0, 1675.0, 1648.0, 1601.0, 1677.0, 1634.0, 1653.0, 1638.0, 1652.0, 1670.0, 1742.0, 1736.0, 1659.0, 1667.0, 1694.0, 1597.0, 1603.0, 1658.0, 1645.0, 1701.0, 1636.0, 1592.0, 1644.0, 1654.0, 1697.0, 1666.0, 1644.0, 1634.0, 1657.0, 1624.0, 1650.0, 1693.0, 1656.0, 1694.0, 1628.0, 1603.0, 1697.0, 1663.0, 1646.0, 1595.0, 1645.0, 1664.0, 1637.0, 1635.0, 1623.0, 1676.0, 1649.0, 1602.0, 1648.0, 1617.0, 1639.0, 1628.0, 1710.0, 1681.0, 1609.0, 1591.0, 1676.0, 1677.0, 1670.0, 1579.0, 1618.0, 1703.0, 1673.0, 1702.0, 1587.0, 1638.0, 1662.0, 1668.0, 1644.0, 1623.0, 1619.0, 1639.0, 1643.0, 1641.0, 1650.0] Lymph-CLL SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7240.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Lymph-CLL SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7240.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Lymph-CLL SBS8 T>A 2053.0 1953.0 2064.91 1986.21 0.8063355539536714 1.0 55.331 7240.0 Lagging 1.051 1.04 1.011 2053.0 2064.91 1994.0 2139.0 [2084.0, 2031.0, 2082.0, 2045.0, 2091.0, 2088.0, 2023.0, 2086.0, 2092.0, 2023.0, 2102.0, 2099.0, 2066.0, 2078.0, 2089.0, 2086.0, 2058.0, 2098.0, 2026.0, 2061.0, 2062.0, 2025.0, 2072.0, 2067.0, 2062.0, 2040.0, 2088.0, 2058.0, 2066.0, 2067.0, 2046.0, 2040.0, 2061.0, 2051.0, 2089.0, 2126.0, 2054.0, 2107.0, 2099.0, 2060.0, 2054.0, 2092.0, 2111.0, 2073.0, 2040.0, 2072.0, 2056.0, 2074.0, 2029.0, 2101.0, 2076.0, 2045.0, 2062.0, 2061.0, 2083.0, 2085.0, 2055.0, 2063.0, 2050.0, 2104.0, 2085.0, 2092.0, 1999.0, 2031.0, 2053.0, 2067.0, 2057.0, 2053.0, 2034.0, 2071.0, 2048.0, 2139.0, 2031.0, 2053.0, 2020.0, 2092.0, 2011.0, 2039.0, 2081.0, 2063.0, 2122.0, 2072.0, 1994.0, 2089.0, 2025.0, 2103.0, 2052.0, 2025.0, 2019.0, 2026.0, 2063.0, 2014.0, 2077.0, 2060.0, 2107.0, 2014.0, 2088.0, 2108.0, 2107.0, 2073.0] 1953.0 1986.21 1922.0 2055.0 [1950.0, 2033.0, 1957.0, 1983.0, 1954.0, 1957.0, 1984.0, 1934.0, 1967.0, 2011.0, 1955.0, 1945.0, 1995.0, 1971.0, 1949.0, 2001.0, 2011.0, 1951.0, 2014.0, 1991.0, 2002.0, 2042.0, 1983.0, 1954.0, 2003.0, 1998.0, 1927.0, 2000.0, 1989.0, 1967.0, 2003.0, 1980.0, 1995.0, 1993.0, 1964.0, 1954.0, 1976.0, 1963.0, 1957.0, 1994.0, 1985.0, 1970.0, 1965.0, 2002.0, 1991.0, 2000.0, 2029.0, 1982.0, 2005.0, 1962.0, 1979.0, 2044.0, 2007.0, 2009.0, 1983.0, 2010.0, 1984.0, 2017.0, 1976.0, 1958.0, 1954.0, 1970.0, 2055.0, 2009.0, 1994.0, 1972.0, 1981.0, 1986.0, 1991.0, 1962.0, 1989.0, 1930.0, 2000.0, 1990.0, 2021.0, 1948.0, 2021.0, 2032.0, 1995.0, 1997.0, 1922.0, 1948.0, 2041.0, 1979.0, 2042.0, 1962.0, 2019.0, 2000.0, 2016.0, 2006.0, 1994.0, 2029.0, 2005.0, 1990.0, 1967.0, 2030.0, 1964.0, 1959.0, 1965.0, 1971.0] Lymph-CLL SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7240.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Lymph-CLL SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7240.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Panc-Endocrine SBS8 C>A 2138.0 2216.0 2180.33 2213.78 0.6380030885508072 1.0 54.289 8020.0 Leading 1.036 1.015 1.021 2138.0 2180.33 2072.0 2265.0 [2234, 2205, 2226, 2199, 2223, 2118, 2175, 2214, 2187, 2189, 2206, 2188, 2187, 2189, 2146, 2173, 2215, 2146, 2180, 2202, 2156, 2227, 2182, 2189, 2123, 2235, 2195, 2168, 2187, 2233, 2231, 2155, 2179, 2185, 2254, 2145, 2173, 2200, 2113, 2199, 2187, 2164, 2193, 2174, 2143, 2167, 2192, 2206, 2149, 2155, 2211, 2220, 2155, 2143, 2154, 2144, 2164, 2231, 2196, 2201, 2217, 2130, 2226, 2178, 2159, 2180, 2175, 2141, 2197, 2155, 2242, 2101, 2177, 2181, 2265, 2191, 2129, 2181, 2142, 2104, 2159, 2233, 2192, 2072, 2090, 2176, 2149, 2213, 2174, 2201, 2241, 2155, 2211, 2206, 2179, 2200, 2161, 2139, 2162, 2169] 2216.0 2213.78 2118.0 2328.0 [2191, 2173, 2193, 2169, 2188, 2272, 2243, 2180, 2213, 2207, 2176, 2229, 2209, 2236, 2271, 2256, 2206, 2261, 2218, 2198, 2237, 2189, 2215, 2236, 2237, 2176, 2210, 2180, 2217, 2168, 2195, 2242, 2226, 2200, 2132, 2247, 2207, 2178, 2248, 2216, 2180, 2234, 2221, 2210, 2213, 2217, 2204, 2157, 2238, 2240, 2179, 2175, 2239, 2243, 2247, 2231, 2225, 2172, 2196, 2191, 2167, 2238, 2165, 2246, 2185, 2222, 2240, 2235, 2207, 2237, 2157, 2289, 2205, 2214, 2138, 2208, 2238, 2201, 2255, 2271, 2208, 2169, 2192, 2328, 2305, 2248, 2230, 2161, 2219, 2188, 2118, 2239, 2187, 2203, 2256, 2200, 2256, 2273, 2219, 2204] Panc-Endocrine SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 8020.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Panc-Endocrine SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 8020.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Panc-Endocrine SBS8 T>A 1896.0 1770.0 1850.96 1804.84 0.3618112395479541 0.75756622805549 45.711 8020.0 Lagging 1.071 1.026 1.044 1896.0 1850.96 1776.0 1925.0 [1850, 1857, 1818, 1878, 1781, 1845, 1842, 1857, 1865, 1791, 1871, 1828, 1874, 1897, 1834, 1854, 1873, 1857, 1832, 1893, 1835, 1839, 1841, 1870, 1874, 1866, 1819, 1863, 1827, 1892, 1885, 1812, 1842, 1883, 1855, 1866, 1861, 1865, 1848, 1880, 1845, 1776, 1847, 1897, 1885, 1836, 1796, 1856, 1883, 1844, 1851, 1866, 1814, 1837, 1855, 1881, 1847, 1863, 1814, 1881, 1879, 1836, 1876, 1881, 1842, 1869, 1880, 1851, 1877, 1809, 1835, 1796, 1841, 1830, 1814, 1816, 1875, 1896, 1862, 1828, 1848, 1925, 1852, 1854, 1882, 1822, 1885, 1864, 1782, 1841, 1824, 1864, 1825, 1886, 1783, 1841, 1867, 1900, 1829, 1835] 1770.0 1804.84 1741.0 1898.0 [1796, 1785, 1838, 1757, 1898, 1827, 1816, 1824, 1805, 1851, 1809, 1828, 1806, 1757, 1818, 1777, 1797, 1815, 1816, 1766, 1817, 1815, 1813, 1784, 1792, 1803, 1824, 1801, 1817, 1771, 1768, 1830, 1853, 1788, 1802, 1793, 1781, 1801, 1790, 1756, 1814, 1854, 1828, 1768, 1777, 1826, 1862, 1829, 1779, 1821, 1786, 1808, 1850, 1801, 1809, 1791, 1841, 1788, 1849, 1795, 1790, 1806, 1764, 1773, 1789, 1781, 1788, 1811, 1771, 1814, 1816, 1843, 1797, 1817, 1846, 1844, 1771, 1741, 1787, 1819, 1796, 1763, 1809, 1792, 1768, 1821, 1795, 1761, 1850, 1811, 1838, 1801, 1803, 1752, 1878, 1843, 1770, 1771, 1807, 1826] Panc-Endocrine SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 8020.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Panc-Endocrine SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 8020.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Prost-AdenoCA SBS8 C>A 1335.0 1413.0 1369.04 1393.14 0.4669830895570186 0.8966901622283733 57.574 4773.0 Leading 1.058 1.018 1.04 1335.0 1369.04 1313.0 1437.0 [1349, 1387, 1415, 1381, 1405, 1342, 1346, 1344, 1379, 1437, 1360, 1396, 1344, 1373, 1393, 1434, 1368, 1339, 1332, 1386, 1400, 1387, 1371, 1356, 1378, 1399, 1390, 1331, 1412, 1373, 1368, 1365, 1328, 1414, 1320, 1332, 1414, 1330, 1382, 1363, 1329, 1353, 1394, 1339, 1348, 1313, 1383, 1404, 1388, 1378, 1352, 1367, 1345, 1367, 1340, 1380, 1392, 1377, 1333, 1377, 1347, 1353, 1411, 1377, 1322, 1358, 1379, 1356, 1405, 1378, 1404, 1393, 1397, 1372, 1360, 1361, 1367, 1391, 1352, 1383, 1333, 1368, 1361, 1376, 1364, 1388, 1379, 1323, 1384, 1352, 1352, 1354, 1360, 1369, 1328, 1349, 1369, 1398, 1367, 1382] 1413.0 1393.14 1328.0 1453.0 [1392, 1380, 1328, 1387, 1329, 1390, 1390, 1435, 1408, 1342, 1415, 1372, 1406, 1381, 1372, 1346, 1425, 1405, 1410, 1369, 1376, 1378, 1388, 1410, 1407, 1371, 1379, 1418, 1371, 1390, 1384, 1385, 1428, 1362, 1453, 1422, 1378, 1447, 1380, 1402, 1417, 1420, 1363, 1414, 1434, 1420, 1367, 1372, 1415, 1392, 1414, 1389, 1423, 1371, 1409, 1381, 1362, 1386, 1424, 1411, 1406, 1421, 1367, 1376, 1450, 1415, 1353, 1394, 1348, 1376, 1363, 1380, 1397, 1388, 1398, 1402, 1391, 1367, 1414, 1376, 1419, 1406, 1408, 1394, 1385, 1379, 1385, 1451, 1382, 1401, 1358, 1398, 1399, 1388, 1421, 1419, 1386, 1371, 1413, 1374] Prost-AdenoCA SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4773.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Prost-AdenoCA SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4773.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Prost-AdenoCA SBS8 T>A 1017.0 1008.0 1039.11 1008.7 0.7539527239096055 1.0 42.426 4773.0 Lagging 1.009 1.03 0.979 1017.0 1039.11 981.0 1086.0 [1050, 1007, 1026, 1054, 1063, 1047, 1042, 1047, 1014, 1063, 997, 1024, 1051, 1028, 1050, 1050, 1034, 1022, 1019, 1036, 1086, 1053, 1018, 1045, 1054, 1053, 1023, 1071, 1033, 1046, 1027, 1022, 1044, 1036, 1010, 1046, 1068, 1061, 1046, 1054, 1011, 1037, 1086, 1062, 1049, 1060, 1030, 1031, 1036, 1078, 1069, 1011, 985, 1082, 997, 1026, 1045, 1005, 986, 1039, 1080, 1069, 1076, 1031, 1051, 1040, 1035, 1043, 1018, 1077, 1065, 1063, 1045, 1017, 1026, 1027, 1028, 1019, 1032, 1028, 1004, 1072, 1012, 1043, 1021, 1064, 1058, 1056, 1033, 1014, 1044, 999, 1040, 1043, 1086, 981, 1017, 1018, 1058, 1033] 1008.0 1008.7 963.0 1065.0 [993, 1029, 1017, 985, 982, 999, 1003, 982, 1032, 986, 1023, 1017, 986, 1019, 1013, 1011, 1030, 992, 1064, 1016, 966, 1007, 1033, 1018, 1005, 1008, 1033, 994, 996, 987, 1023, 1015, 1010, 998, 1011, 1002, 976, 999, 1006, 999, 1047, 1022, 963, 990, 993, 973, 992, 1028, 1022, 976, 982, 1044, 1056, 980, 1065, 1026, 977, 1045, 1034, 1007, 983, 986, 995, 1031, 998, 1028, 995, 996, 1028, 970, 978, 999, 1016, 1032, 1013, 1022, 1031, 1036, 1004, 1012, 1042, 977, 1026, 992, 1026, 988, 971, 979, 1028, 1025, 997, 1057, 1029, 1008, 975, 1053, 1029, 1033, 974, 1021] Prost-AdenoCA SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4773.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Prost-AdenoCA SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4773.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS8 C>A 533.0 584.0 555.02 569.51 0.4468524447168372 0.8736573187054504 43.959 2541.0 Leading 1.096 1.026 1.068 533.0 555.02 509.0 600.0 [551, 549, 559, 549, 545, 572, 572, 541, 571, 547, 563, 539, 540, 553, 555, 550, 519, 567, 569, 545, 549, 575, 586, 538, 542, 542, 549, 573, 527, 568, 542, 563, 563, 553, 566, 513, 513, 551, 559, 573, 548, 568, 572, 546, 569, 547, 566, 551, 509, 538, 591, 569, 565, 600, 564, 568, 543, 545, 544, 554, 555, 561, 533, 528, 565, 564, 591, 566, 558, 561, 565, 564, 535, 555, 545, 564, 545, 557, 542, 568, 573, 538, 588, 511, 568, 552, 560, 539, 591, 550, 568, 581, 549, 549, 563, 535, 565, 555, 528, 559] 584.0 569.51 537.0 609.0 [574, 555, 577, 587, 573, 540, 562, 581, 565, 573, 553, 586, 585, 579, 565, 569, 608, 549, 546, 571, 568, 554, 553, 572, 578, 600, 558, 556, 584, 557, 583, 572, 563, 570, 547, 608, 603, 585, 577, 575, 577, 552, 558, 576, 556, 591, 572, 553, 609, 583, 544, 558, 560, 544, 568, 567, 569, 567, 575, 591, 578, 565, 591, 573, 563, 565, 537, 564, 571, 560, 553, 559, 574, 583, 579, 560, 581, 567, 585, 558, 559, 589, 544, 603, 556, 560, 561, 582, 557, 561, 560, 555, 567, 568, 567, 595, 557, 560, 589, 564] Stomach-AdenoCA SBS8 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2541.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS8 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2541.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS8 T>A 699.0 725.0 729.03 703.5 0.3494783076560586 0.7416815689804916 56.041 2541.0 Leading 1.037 0.965 1.075 699.0 729.03 676.0 780.0 [705, 687, 694, 726, 711, 723, 775, 718, 735, 722, 741, 701, 750, 707, 733, 738, 754, 737, 736, 717, 739, 718, 706, 713, 705, 717, 759, 758, 740, 761, 726, 708, 771, 780, 754, 727, 745, 734, 724, 702, 676, 721, 719, 729, 757, 711, 763, 762, 738, 705, 695, 709, 727, 736, 715, 721, 726, 748, 736, 729, 739, 738, 689, 719, 748, 760, 746, 731, 703, 734, 752, 729, 737, 728, 714, 733, 741, 708, 759, 721, 707, 738, 745, 747, 719, 738, 755, 706, 722, 719, 719, 691, 713, 734, 746, 745, 718, 699, 742, 751] 725.0 703.5 657.0 748.0 [697, 744, 740, 718, 716, 707, 672, 715, 714, 712, 688, 733, 685, 710, 704, 695, 697, 693, 690, 721, 704, 704, 710, 732, 717, 705, 676, 699, 671, 657, 709, 721, 686, 662, 686, 705, 683, 697, 694, 721, 741, 692, 729, 718, 673, 706, 689, 693, 679, 738, 719, 731, 715, 717, 718, 722, 683, 675, 712, 715, 700, 705, 727, 719, 699, 679, 681, 710, 728, 690, 682, 706, 723, 699, 717, 684, 700, 704, 668, 722, 706, 706, 689, 700, 705, 702, 685, 721, 715, 707, 699, 748, 724, 686, 671, 694, 716, 725, 682, 671] Stomach-AdenoCA SBS8 T>C 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2541.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS8 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2541.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Summary across all cancer types signature mutation_type strand fold_change_1.1 len(fold_change_1.1_cancer_types) fold_change_1.2 len(fold_change_1.2_cancer_types) fold_change_1.3 len(fold_change_1.3_cancer_types) fold_change_1.5 len(fold_change_1.5_cancer_types) fold_change_1.75 len(fold_change_1.75_cancer_types) fold_change_2+ len(fold_change_2+_cancer_types) all_cancer_types_list len(all_cancer_types_list) avg_fold_change SBS8 T>A Leading [] 0 [] 0 [] 0 [] 0 [] 0 [] 0 ['Bladder-TCC', 'Breast-Cancer', 'CNS-Medullo', 'ESCC', 'Lymph-CLL', 'Panc-Endocrine', 'Prost-AdenoCA', 'Stomach-AdenoCA'] 8