# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	cutoff	number_of_mutations	average_probability	file_name	pearson_corr	pearson_p_value	pearson_q_value	real_average_number_of_overlaps	sims_average_number_of_overlaps	avg_real_signal	sim_data_avg_signal	fold_change	real_average_signal_array	sims_average_signal_array
SBS85	Lymph-BNHL	0.6	13773	0.751	SBS85_ENCFF449NOT_B-cell_Normal_CTCF-human_AverageSignalArray.txt	1.0	0.0	0.0	210.68	63.586	118.991	184.21	0.646	[148.372, 148.77, 148.601, 148.601, 149.002, 149.002, 147.531, 147.358, 147.079, 147.145, 146.914, 146.942, 146.558, 146.557, 147.11, 147.484, 147.288, 147.93, 147.788, 147.788, 147.788, 148.216, 148.613, 149.052, 149.965, 149.283, 148.244, 148.454, 147.765, 147.925, 148.91, 150.589, 150.589, 150.589, 150.387, 148.688, 148.688, 148.436, 148.436, 148.82, 148.677, 147.692, 147.692, 146.482, 146.262, 147.936, 147.936, 147.936, 148.383, 148.383, 148.281, 148.16, 148.16, 149.412, 148.992, 149.363, 149.806, 150.231, 150.231, 149.528, 149.528, 149.583, 150.044, 150.363, 149.818, 150.262, 150.103, 150.541, 149.629, 149.326, 149.326, 148.176, 148.176, 147.672, 147.638, 148.196, 148.948, 147.105, 147.105, 148.843, 148.904, 149.187, 149.187, 149.187, 149.823, 150.62, 150.073, 149.532, 148.768, 146.996, 146.364, 146.943, 146.943, 146.971, 146.546, 146.546, 146.408, 145.982, 146.031, 146.031, 146.248, 146.036, 147.564, 147.564, 147.714, 147.714, 147.91, 148.407, 149.699, 149.699, 150.327, 150.534, 150.591, 151.047, 151.047, 151.675, 151.675, 152.455, 152.736, 153.249, 153.392, 153.081, 153.603, 152.777, 152.777, 152.777, 152.777, 152.777, 152.777, 152.777, 153.833, 153.833, 153.833, 154.063, 154.909, 154.909, 155.863, 155.863, 156.296, 156.296, 156.009, 156.044, 154.9, 154.49, 153.986, 154.544, 154.544, 153.021, 154.075, 153.548, 152.966, 153.11, 153.11, 153.243, 153.243, 153.243, 153.243, 153.59, 153.59, 154.551, 155.101, 154.261, 154.625, 154.721, 154.721, 154.144, 153.519, 153.55, 154.589, 153.995, 152.983, 152.983, 152.619, 152.743, 153.382, 153.632, 154.903, 154.903, 156.385, 156.385, 156.196, 156.196, 157.781, 157.781, 157.157, 155.749, 155.749, 155.821, 156.899, 156.899, 156.899, 156.899, 156.899, 158.571, 159.088, 159.088, 159.088, 160.086, 161.253, 160.76, 160.315, 160.315, 160.453, 159.37, 159.629, 159.629, 159.629, 159.629, 158.784, 158.232, 157.156, 157.156, 157.156, 155.955, 155.307, 155.338, 155.451, 156.054, 157.991, 158.029, 157.337, 156.291, 155.624, 154.857, 153.239, 152.701, 152.701, 152.733, 152.195, 151.624, 151.163, 151.163, 150.027, 150.584, 150.182, 150.182, 150.888, 150.919, 150.683, 149.953, 150.33, 148.118, 148.118, 148.077, 146.675, 146.713, 146.713, 145.654, 145.654, 146.063, 143.76, 143.76, 143.807, 143.431, 143.431, 143.431, 143.952, 143.435, 144.365, 143.424, 143.424, 142.48, 142.917, 142.582, 142.582, 142.582, 142.582, 142.989, 143.508, 142.577, 143.748, 143.748, 143.748, 143.748, 143.264, 142.752, 143.264, 143.05, 142.823, 141.053, 140.041, 139.179, 138.743, 138.743, 138.743, 138.743, 140.444, 140.779, 140.464, 140.751, 140.751, 141.447, 140.832, 140.832, 140.75, 140.538, 140.339, 140.339, 139.485, 138.665, 139.429, 139.429, 139.936, 139.936, 139.852, 139.69, 139.205, 137.622, 137.104, 137.104, 137.104, 136.644, 137.831, 137.36, 135.545, 136.284, 135.39, 135.88, 136.108, 136.108, 135.59, 136.046, 136.922, 136.313, 136.396, 136.396, 134.667, 134.667, 134.772, 134.772, 133.42, 133.42, 133.207, 133.273, 133.741, 134.336, 134.846, 135.841, 135.341, 134.919, 134.425, 134.425, 134.894, 134.384, 134.878, 133.977, 133.506, 133.538, 133.823, 133.823, 134.383, 133.043, 133.152, 133.152, 134.178, 133.747, 134.25, 134.279, 134.279, 134.279, 134.314, 133.536, 132.194, 132.133, 132.133, 132.634, 132.982, 134.005, 134.005, 133.814, 133.814, 133.457, 133.457, 133.338, 133.737, 132.788, 133.018, 133.018, 133.274, 133.274, 132.757, 133.118, 133.118, 132.609, 133.151, 132.969, 133.276, 134.285, 134.285, 134.27, 134.27, 133.296, 133.296, 134.896, 134.896, 136.227, 135.387, 131.206, 132.26, 132.26, 131.896, 132.049, 132.049, 130.588, 131.621, 132.11, 132.11, 131.485, 131.138, 130.572, 130.304, 130.304, 127.599, 127.981, 127.981, 127.981, 127.705, 127.705, 128.53, 128.53, 128.53, 128.53, 128.53, 128.118, 129.31, 129.872, 129.51, 129.51, 129.844, 128.446, 127.036, 125.737, 124.596, 125.881, 125.881, 125.934, 125.934, 125.64, 125.64, 125.64, 125.621, 126.293, 125.786, 125.786, 125.78, 126.119, 126.987, 126.987, 126.518, 126.518, 126.518, 124.582, 124.582, 122.633, 122.359, 121.793, 121.793, 121.853, 119.609, 120.064, 120.064, 120.335, 120.335, 120.335, 120.335, 121.474, 121.314, 120.841, 120.414, 120.414, 118.022, 118.247, 118.556, 118.556, 120.406, 119.698, 122.334, 121.885, 121.885, 123.522, 123.522, 123.522, 124.524, 124.524, 124.155, 124.155, 123.666, 124.195, 124.101, 123.907, 125.832, 125.832, 125.832, 125.832, 125.052, 125.052, 124.944, 125.499, 122.076, 122.107, 121.603, 115.725, 115.725, 115.725, 115.725, 116.038, 116.354, 116.498, 116.498, 116.537, 117.826, 117.577, 117.577, 116.601, 116.148, 115.867, 115.112, 114.041, 114.041, 114.041, 113.982, 113.982, 113.982, 113.982, 113.982, 115.331, 115.643, 115.643, 115.643, 115.643, 116.137, 115.946, 115.946, 115.946, 115.946, 115.819, 115.819, 115.506, 115.506, 115.506, 116.024, 116.024, 115.134, 115.134, 113.979, 113.979, 113.979, 113.879, 113.521, 113.256, 111.058, 111.622, 111.197, 111.197, 111.197, 111.197, 112.209, 112.209, 112.209, 112.209, 112.729, 113.246, 112.991, 112.743, 112.743, 109.89, 109.887, 109.887, 110.581, 111.094, 112.469, 112.469, 112.009, 113.014, 113.014, 113.014, 113.014, 114.122, 114.629, 114.629, 113.267, 112.78, 110.749, 112.511, 112.511, 114.107, 114.353, 114.353, 114.932, 114.434, 113.899, 113.734, 114.902, 114.178, 115.758, 115.758, 115.758, 115.758, 115.758, 115.401, 114.557, 114.557, 114.448, 116.004, 117.266, 117.266, 115.253, 116.789, 116.789, 116.846, 116.347, 116.081, 115.681, 114.883, 114.883, 114.883, 114.883, 115.39, 115.39, 115.084, 114.705, 113.974, 112.446, 112.841, 112.483, 111.547, 111.547, 111.639, 111.639, 111.639, 112.868, 112.868, 113.276, 115.196, 114.777, 114.777, 114.777, 114.777, 114.301, 114.724, 114.378, 113.961, 113.677, 114.172, 114.172, 114.172, 114.172, 114.172, 114.511, 115.442, 113.706, 113.706, 113.286, 111.417, 108.398, 108.453, 108.453, 107.666, 109.579, 109.579, 109.579, 108.885, 108.885, 108.885, 108.885, 108.885, 108.885, 108.885, 107.636, 107.243, 107.243, 105.454, 105.454, 105.454, 105.073, 105.028, 105.466, 105.521, 105.861, 107.386, 107.589, 106.081, 106.081, 106.081, 106.081, 105.983, 105.885, 106.007, 106.007, 106.007, 106.464, 106.942, 106.942, 106.942, 106.942, 107.419, 107.626, 107.326, 105.566, 105.939, 105.999, 106.419, 106.419, 106.904, 106.458, 106.458, 106.799, 106.799, 105.19, 105.19, 104.936, 104.936, 105.39, 105.43, 105.358, 105.358, 105.269, 105.687, 105.95, 105.24, 104.843, 105.168, 104.724, 105.617, 107.055, 107.055, 107.047, 107.998, 107.998, 106.588, 106.588, 106.588, 106.588, 107.043, 107.044, 107.044, 107.044, 107.376, 107.435, 108.4, 108.4, 108.289, 107.829, 107.046, 107.046, 107.091, 106.291, 106.291, 106.291, 107.576, 108.572, 109.028, 108.617, 108.776, 109.251, 110.524, 111.022, 111.022, 111.022, 111.022, 110.777, 110.777, 110.351, 110.351, 109.904, 108.705, 107.831, 107.831, 107.188, 106.638, 106.638, 107.755, 108.087, 109.271, 109.009, 109.009, 108.503, 108.503, 108.09, 107.769, 107.769, 108.126, 108.027, 108.347, 109.046, 109.046, 109.046, 108.787, 108.538, 108.558, 106.742, 105.692, 106.039, 106.039, 105.814, 105.579, 106.032, 106.032, 105.7, 104.443, 104.621, 105.524, 105.524, 106.419, 106.728, 106.778, 107.063, 106.82, 106.832, 107.262, 107.726, 109.326, 109.106, 109.191, 109.627, 109.569, 110.007, 109.734, 109.734, 113.795, 113.849, 113.394, 113.3, 113.786, 113.786, 113.549, 114.029, 114.029, 114.029, 113.741, 113.741, 113.741, 113.741, 113.741, 113.741, 113.741, 113.405, 113.405, 113.696, 113.859, 113.859, 113.859, 114.775, 114.775, 114.775, 114.775, 114.775, 114.535, 114.535, 114.535, 116.564, 116.141, 115.152, 115.152, 114.719, 114.719, 114.914, 114.914, 114.914, 115.366, 115.366, 115.366, 115.848, 115.848, 113.755, 113.884, 113.509, 113.1, 113.726, 113.726, 114.356, 114.477, 114.477, 114.926, 114.926, 114.106, 114.393, 113.021, 112.291, 112.733, 112.733, 113.621, 112.679, 111.7, 109.39, 109.855, 109.606, 109.606, 110.067, 110.532, 110.532, 110.532, 111.677, 110.621, 110.621, 109.671, 109.459, 109.459, 108.976, 108.918, 111.701, 111.434, 111.206, 111.206, 111.206, 111.206, 111.678, 111.614, 111.614, 111.798, 111.756, 112.635, 112.635, 112.863, 113.121, 112.538, 112.976, 113.366, 113.832, 113.884, 114.246, 114.246, 114.246, 114.246, 114.655, 114.655, 115.059, 114.999, 114.999, 114.999, 115.241, 116.126, 116.126, 116.126, 117.115, 117.019, 116.631, 116.631, 116.419, 116.353, 115.762, 115.762, 116.913, 116.956, 117.385, 117.385, 117.827, 118.073, 117.781, 117.305, 117.416, 117.416, 117.177, 115.655, 117.118, 117.656, 117.656, 117.656, 117.372, 117.372, 117.706, 117.706, 118.167, 116.991, 116.991, 117.161, 117.161, 116.255, 115.959, 116.219, 116.325, 116.325, 116.325, 116.39, 116.837, 117.305, 117.305, 117.31, 116.975, 116.639, 116.685, 116.685, 116.685, 118.17, 119.457, 120.045, 121.717, 121.717, 121.717, 122.713, 123.748, 122.985, 122.344, 122.344, 122.344, 122.344, 121.932, 121.932, 121.932, 121.634, 121.283]	[179.995, 179.935, 179.824, 180.089, 180.409, 180.515, 180.468, 180.699, 180.862, 180.987, 181.083, 181.434, 181.277, 181.428, 181.572, 181.444, 181.382, 181.436, 181.37, 181.512, 181.464, 181.395, 181.393, 181.565, 181.549, 181.33, 181.243, 181.255, 181.256, 181.32, 181.46, 181.551, 181.684, 181.817, 181.973, 181.965, 182.022, 182.157, 182.181, 182.114, 182.212, 182.38, 182.416, 182.292, 182.225, 182.026, 182.148, 181.986, 182.088, 182.154, 182.064, 182.073, 181.904, 182.084, 182.198, 182.05, 182.175, 182.201, 182.363, 182.551, 182.653, 182.341, 182.475, 182.327, 182.482, 182.376, 182.306, 182.36, 182.439, 182.59, 182.602, 182.705, 182.58, 182.39, 182.507, 182.637, 182.416, 182.755, 183.092, 183.072, 183.199, 183.111, 183.194, 183.225, 183.166, 183.154, 183.288, 183.15, 183.268, 183.265, 183.212, 183.241, 183.175, 183.271, 183.061, 182.942, 182.892, 182.878, 182.809, 182.716, 182.878, 182.935, 182.821, 182.58, 182.598, 182.774, 182.936, 182.577, 182.561, 182.432, 182.528, 182.515, 182.536, 182.482, 182.764, 182.705, 182.678, 182.624, 182.447, 182.418, 182.362, 182.495, 182.508, 182.233, 182.372, 182.333, 182.429, 182.338, 182.282, 182.44, 182.476, 182.427, 182.438, 182.537, 182.235, 182.127, 182.112, 182.144, 182.196, 182.174, 182.387, 182.159, 182.103, 181.973, 182.02, 181.922, 182.131, 182.062, 181.95, 182.154, 182.039, 181.955, 181.849, 181.941, 181.928, 181.948, 181.964, 181.778, 181.555, 181.632, 181.857, 181.799, 181.875, 181.844, 181.634, 181.819, 181.707, 181.565, 181.455, 181.397, 181.506, 181.212, 181.309, 181.057, 180.887, 180.773, 180.774, 180.662, 180.721, 180.641, 180.57, 180.408, 180.533, 180.54, 180.687, 180.734, 180.709, 180.671, 180.604, 180.603, 180.94, 180.922, 180.928, 180.97, 181.175, 181.265, 181.343, 181.356, 181.229, 181.276, 181.44, 181.362, 181.298, 181.268, 181.331, 181.463, 181.616, 181.631, 181.752, 181.64, 181.807, 181.925, 182.157, 182.136, 182.0, 182.029, 182.168, 182.283, 182.12, 181.936, 181.859, 181.803, 181.663, 181.724, 181.787, 181.622, 181.606, 181.582, 181.695, 181.569, 181.633, 181.363, 181.4, 181.222, 181.232, 181.315, 181.329, 181.414, 181.523, 181.574, 181.474, 181.308, 181.25, 181.225, 181.116, 180.909, 181.143, 181.226, 181.209, 181.23, 181.33, 181.298, 181.15, 180.973, 180.867, 180.709, 180.551, 180.717, 180.889, 180.573, 180.505, 180.505, 180.663, 180.56, 180.362, 180.245, 180.036, 179.802, 179.787, 179.751, 179.655, 179.475, 179.684, 179.396, 179.715, 179.852, 179.817, 179.864, 180.042, 180.121, 180.042, 179.952, 179.878, 179.721, 179.757, 179.587, 179.488, 179.334, 179.493, 179.212, 178.968, 179.084, 179.105, 179.257, 179.332, 179.463, 179.364, 179.528, 179.355, 179.315, 179.275, 179.54, 179.451, 179.488, 179.736, 179.518, 179.597, 179.486, 179.458, 179.607, 179.569, 179.609, 179.39, 179.428, 179.254, 179.221, 178.869, 179.03, 179.05, 178.938, 178.666, 178.688, 178.399, 178.451, 178.163, 178.309, 178.111, 178.182, 178.07, 178.116, 178.033, 177.999, 177.985, 177.787, 177.847, 177.912, 177.922, 177.813, 177.965, 177.995, 178.019, 178.044, 178.22, 178.295, 178.419, 178.516, 178.534, 178.418, 178.276, 178.399, 178.666, 178.661, 178.606, 178.657, 178.761, 178.744, 178.748, 179.137, 179.115, 178.988, 178.816, 178.879, 179.099, 179.181, 179.105, 179.175, 179.293, 179.516, 179.848, 179.957, 179.982, 179.914, 179.8, 179.696, 179.894, 180.004, 179.938, 179.753, 179.867, 179.725, 179.687, 179.652, 179.648, 179.643, 179.56, 179.599, 179.48, 179.568, 179.614, 179.806, 179.704, 179.699, 179.625, 179.572, 179.667, 179.796, 179.875, 179.948, 180.086, 179.951, 180.001, 180.082, 180.071, 179.913, 180.221, 180.073, 180.156, 180.381, 180.481, 180.511, 180.702, 180.474, 180.619, 180.789, 180.794, 180.904, 181.016, 180.612, 180.727, 180.794, 180.96, 180.984, 181.201, 181.26, 181.371, 181.766, 181.729, 181.693, 181.877, 181.784, 181.826, 181.966, 181.67, 181.826, 181.754, 181.838, 181.728, 181.928, 181.817, 182.016, 182.275, 181.985, 181.864, 182.051, 182.087, 182.0, 182.283, 182.292, 181.934, 182.11, 182.023, 182.244, 182.303, 182.648, 182.724, 182.767, 182.716, 182.946, 183.11, 183.469, 183.467, 183.617, 183.403, 183.509, 183.581, 183.543, 183.525, 183.45, 183.473, 183.393, 183.353, 183.151, 182.809, 183.112, 183.243, 183.325, 183.382, 183.395, 183.6, 183.73, 183.662, 183.6, 183.643, 183.775, 183.536, 183.715, 183.844, 183.897, 184.132, 184.412, 184.499, 184.395, 184.398, 184.642, 184.384, 184.573, 184.892, 185.017, 184.995, 184.86, 185.143, 185.104, 185.028, 185.116, 185.134, 185.119, 185.13, 184.889, 184.942, 184.963, 184.902, 184.832, 184.926, 184.806, 184.748, 184.759, 184.743, 184.892, 185.052, 185.21, 185.255, 185.123, 184.993, 185.291, 185.23, 185.156, 185.144, 185.045, 184.878, 184.611, 184.591, 184.417, 184.579, 184.529, 184.511, 184.358, 184.673, 184.756, 184.711, 184.551, 184.5, 184.309, 184.264, 184.384, 184.658, 184.525, 184.569, 184.698, 184.728, 184.617, 184.611, 184.528, 184.582, 184.317, 184.264, 184.329, 184.477, 184.612, 184.495, 184.508, 184.758, 185.128, 185.014, 184.739, 184.69, 184.665, 184.687, 184.239, 184.41, 184.565, 184.316, 184.524, 184.589, 184.562, 184.584, 184.623, 184.683, 184.724, 185.029, 185.19, 185.117, 184.914, 184.726, 184.647, 184.742, 184.954, 184.924, 184.943, 184.736, 184.755, 184.692, 184.583, 184.562, 184.611, 184.579, 184.64, 184.621, 184.819, 185.032, 185.138, 185.293, 185.166, 184.956, 184.728, 184.685, 184.497, 184.551, 184.459, 184.408, 184.37, 184.44, 184.508, 184.53, 184.696, 184.779, 185.007, 185.219, 185.09, 185.115, 185.16, 185.159, 185.285, 185.115, 185.441, 185.448, 185.567, 185.724, 185.372, 185.377, 185.359, 185.573, 185.6, 185.435, 185.439, 185.473, 185.436, 185.216, 185.268, 185.13, 184.965, 184.852, 185.023, 185.03, 184.962, 185.197, 185.311, 185.246, 185.458, 185.526, 185.686, 185.629, 185.502, 185.496, 185.616, 185.546, 185.272, 185.233, 185.254, 185.386, 185.213, 185.19, 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