# Only cancer types with minimum 2000 mutations for SBS signatures with average probability at least 0.75 are considered. signature cancer_type processive_group_length number_of_processive_groups log10_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_number_of_processive_groups SBS7c Skin-Melanoma 2 9059 3.957 0.48 6233.0 6639.0 6411.48 79.418 3.486057863396505e-239 8.053995753364338e-239 238.094 [6441, 6530, 6539, 6467, 6465, 6395, 6420, 6443, 6307, 6341, 6503, 6450, 6233, 6376, 6512, 6551, 6449, 6391, 6381, 6357, 6478, 6352, 6285, 6454, 6467, 6468, 6437, 6534, 6320, 6473, 6500, 6310, 6358, 6333, 6451, 6320, 6400, 6366, 6345, 6440, 6460, 6324, 6519, 6400, 6311, 6456, 6286, 6361, 6388, 6465, 6448, 6391, 6414, 6445, 6530, 6403, 6288, 6289, 6495, 6490, 6391, 6243, 6301, 6316, 6513, 6639, 6316, 6416, 6438, 6517, 6517, 6408, 6392, 6344, 6409, 6465, 6428, 6417, 6305, 6372, 6320, 6317, 6356, 6429, 6251, 6392, 6464, 6466, 6424, 6461, 6404, 6392, 6548, 6424, 6526, 6440, 6409, 6506, 6373, 6294] SBS7c Skin-Melanoma 3 232 2.365 0.287 67.0 112.0 90.37 8.886 2.110792430336385e-56 3.214161200739496e-56 55.493 [103, 92, 107, 67, 100, 85, 91, 76, 101, 91, 96, 101, 86, 78, 85, 80, 106, 76, 89, 90, 112, 94, 86, 95, 82, 83, 99, 76, 77, 87, 87, 93, 83, 86, 90, 91, 87, 100, 75, 86, 88, 85, 83, 82, 84, 88, 85, 80, 97, 96, 104, 96, 87, 97, 93, 81, 87, 90, 103, 84, 110, 91, 81, 87, 83, 88, 87, 94, 101, 87, 105, 90, 86, 90, 107, 105, 89, 79, 100, 106, 99, 96, 103, 90, 92, 85, 91, 89, 102, 86, 96, 97, 96, 79, 79, 83, 90, 78, 97, 84] SBS7c Skin-Melanoma 4 16 1.204 0.146 1.0 5.0 2.188 1.023 6.698248714416999e-41 8.975653277318778e-41 40.047 [4, 2, 4, 2, 1, 2, 1, 2, 1, 2, 3, 3, 2, 2, 3, 3, 2, 4, 2, 1, 4, 1, 2, 2, 1, 3, 3, 3, 4, 3, 1, 2, 2, 3, 1, 1, 1, 1, 1, 2, 2, 2, 1, 3, 3, 1, 1, 1, 2, 1, 2, 2, 3, 3, 1, 3, 3, 1, 3, 3, 2, 2, 3, 1, 3, 2, 2, 4, 1, 3, 5, 4, 3, 1, 2, 1, 1, 3, 4, 3, 2, 3, 1, 1, 1] SBS7c Skin-Melanoma 5 2 0.301 0.037 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1, 1] SBS7c Skin-Melanoma 6 3 0.477 0.058 inf [] signature cancer_type processive_group_length avg_number_of_processive_groups log10_avg_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_avg_number_of_processive_groups SBS7c ACROSS_ALL_CANCER_TYPES 2 9059.0 3.957 0.48 6233.0 6639.0 6411.48 79.418 3.4860578633965062e-239 6.9721157267930124e-239 238.157 [6441.0, 6530.0, 6539.0, 6467.0, 6465.0, 6395.0, 6420.0, 6443.0, 6307.0, 6341.0, 6503.0, 6450.0, 6233.0, 6376.0, 6512.0, 6551.0, 6449.0, 6391.0, 6381.0, 6357.0, 6478.0, 6352.0, 6285.0, 6454.0, 6467.0, 6468.0, 6437.0, 6534.0, 6320.0, 6473.0, 6500.0, 6310.0, 6358.0, 6333.0, 6451.0, 6320.0, 6400.0, 6366.0, 6345.0, 6440.0, 6460.0, 6324.0, 6519.0, 6400.0, 6311.0, 6456.0, 6286.0, 6361.0, 6388.0, 6465.0, 6448.0, 6391.0, 6414.0, 6445.0, 6530.0, 6403.0, 6288.0, 6289.0, 6495.0, 6490.0, 6391.0, 6243.0, 6301.0, 6316.0, 6513.0, 6639.0, 6316.0, 6416.0, 6438.0, 6517.0, 6517.0, 6408.0, 6392.0, 6344.0, 6409.0, 6465.0, 6428.0, 6417.0, 6305.0, 6372.0, 6320.0, 6317.0, 6356.0, 6429.0, 6251.0, 6392.0, 6464.0, 6466.0, 6424.0, 6461.0, 6404.0, 6392.0, 6548.0, 6424.0, 6526.0, 6440.0, 6409.0, 6506.0, 6373.0, 6294.0] SBS7c ACROSS_ALL_CANCER_TYPES 3 232.0 2.365 0.287 67.0 112.0 90.37 8.886 2.1107924303363856e-56 2.814389907115181e-56 55.551 [103.0, 92.0, 107.0, 67.0, 100.0, 85.0, 91.0, 76.0, 101.0, 91.0, 96.0, 101.0, 86.0, 78.0, 85.0, 80.0, 106.0, 76.0, 89.0, 90.0, 112.0, 94.0, 86.0, 95.0, 82.0, 83.0, 99.0, 76.0, 77.0, 87.0, 87.0, 93.0, 83.0, 86.0, 90.0, 91.0, 87.0, 100.0, 75.0, 86.0, 88.0, 85.0, 83.0, 82.0, 84.0, 88.0, 85.0, 80.0, 97.0, 96.0, 104.0, 96.0, 87.0, 97.0, 93.0, 81.0, 87.0, 90.0, 103.0, 84.0, 110.0, 91.0, 81.0, 87.0, 83.0, 88.0, 87.0, 94.0, 101.0, 87.0, 105.0, 90.0, 86.0, 90.0, 107.0, 105.0, 89.0, 79.0, 100.0, 106.0, 99.0, 96.0, 103.0, 90.0, 92.0, 85.0, 91.0, 89.0, 102.0, 86.0, 96.0, 97.0, 96.0, 79.0, 79.0, 83.0, 90.0, 78.0, 97.0, 84.0] SBS7c ACROSS_ALL_CANCER_TYPES 4 16.0 1.204 0.146 1.0 5.0 2.188 1.023 6.698248714416999e-41 6.698248714416999e-41 40.174 [4.0, 2.0, 4.0, 2.0, 1.0, 2.0, 1.0, 2.0, 1.0, 2.0, 3.0, 3.0, 2.0, 2.0, 3.0, 3.0, 2.0, 4.0, 2.0, 1.0, 4.0, 1.0, 2.0, 2.0, 1.0, 3.0, 3.0, 3.0, 4.0, 3.0, 1.0, 2.0, 2.0, 3.0, 1.0, 1.0, 1.0, 1.0, 1.0, 2.0, 2.0, 2.0, 1.0, 3.0, 3.0, 1.0, 1.0, 1.0, 2.0, 1.0, 2.0, 2.0, 3.0, 3.0, 1.0, 3.0, 3.0, 1.0, 3.0, 3.0, 2.0, 2.0, 3.0, 1.0, 3.0, 2.0, 2.0, 4.0, 1.0, 3.0, 5.0, 4.0, 3.0, 1.0, 2.0, 1.0, 1.0, 3.0, 4.0, 3.0, 2.0, 3.0, 1.0, 1.0, 1.0] SBS7c ACROSS_ALL_CANCER_TYPES 5 2.0 0.301 0.037 1.0 1.0 1.0 0.0 0.0 0.0 inf [1.0, 1.0, 1.0] SBS7c ACROSS_ALL_CANCER_TYPES 6 3.0 0.477 0.058 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]