# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	dna_element	encode_element_list	fold_change_list	avg_fold_change	p_value_list	combined_p_value	q_value
SBS7c	Skin-Melanoma	H3K27ac-human	['ENCFF731TOU_foreskin-fibroblast_Normal_H3K27ac-human', 'ENCFF704UVU_foreskin-melanocyte_Normal_H3K27ac-human']	[0.965, 0.968]	0.966	[1.6375524316375515e-10, 2.898727900772521e-07]	1.8316299491164917e-15	7.1205310179939e-15
SBS7c	Skin-Melanoma	H3K27me3-human	['ENCFF260QSX_foreskin-fibroblast_Normal_H3K27me3-human', 'ENCFF640WPP_foreskin-melanocyte_Normal_H3K27me3-human']	[0.955, 0.896]	0.926	[2.4278808183113146e-37, 5.37640724112744e-110]	4.397791876832791e-144	4.726702361738772e-143
SBS7c	Skin-Melanoma	H3K36me3-human	['ENCFF778WQB_foreskin-fibroblast_Normal_H3K36me3-human', 'ENCFF377DZS_foreskin-melanocyte_Normal_H3K36me3-human']	[0.999, 0.996]	0.998	[0.7390449226427935, 0.02571906496975695]	0.09433290896712732	0.1454804548661043
SBS7c	Skin-Melanoma	H3K4me1-human	['ENCFF772YVC_foreskin-fibroblast_Normal_H3K4me1-human', 'ENCFF234OVO_foreskin-melanocyte_Normal_H3K4me1-human']	[0.958, 0.984]	0.971	[2.1779372510064248e-88, 1.4152378837734112e-07]	6.738519906923082e-93	5.903128055448371e-92
SBS7c	Skin-Melanoma	H3K4me3-human	['ENCFF644IVA_foreskin-fibroblast_Normal_H3K4me3-human', 'ENCFF499KTB_foreskin-melanocyte_Normal_H3K4me3-human', 'ENCFF496WOM_lower-leg-skin_Normal_H3K4me3-human']	[0.912, 0.965, 0.871]	0.916	[5.772581828002187e-44, 3.482839640015188e-08, 1.4951214573375536e-48]	7.803273364284024e-95	6.883025264082252e-94
SBS7c	Skin-Melanoma	H3K9ac-human	['ENCFF973JPP_foreskin-melanocyte_Normal_H3K9ac-human']	[0.828]	0.828	[1.160741151396299e-59]	1.1607411513963e-59	8.278371371575469e-59
SBS7c	Skin-Melanoma	H3K9me3-human	['ENCFF342TCS_foreskin-fibroblast_Normal_H3K9me3-human', 'ENCFF849GBJ_foreskin-melanocyte_Normal_H3K9me3-human']	[1.005, 1.0]	1.003	[0.009037799379341712, 0.9475969834425324]	0.04933116048132232	0.0819764672008808