# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. signature cancer_type dna_element encode_element_list fold_change_list avg_fold_change p_value_list combined_p_value q_value SBS58 Prost-AdenoCA H3K27ac-human ['ENCFF300WCK_epithelial-cell-of-prostate_Normal_H3K27ac-human', 'ENCFF002NFG_prostate-gland_Normal_H3K27ac-human', 'ENCFF063VHN_prostate-gland_Normal_H3K27ac-human'] [1.095, 0.95, 1.008] 1.018 [0.17248255867350426, 0.31594695531841277, 0.8688644676409156] 0.41203597427451644 0.510983204037272 SBS58 Skin-Melanoma H3K27me3-human ['ENCFF260QSX_foreskin-fibroblast_Normal_H3K27me3-human', 'ENCFF640WPP_foreskin-melanocyte_Normal_H3K27me3-human'] [1.009, 0.992] 1.001 [0.7623524437428421, 0.8890409354036082] 0.9413838934751325 0.9630605001626538 SBS58 Skin-Melanoma H3K36me3-human ['ENCFF778WQB_foreskin-fibroblast_Normal_H3K36me3-human', 'ENCFF377DZS_foreskin-melanocyte_Normal_H3K36me3-human'] [0.93, 1.011] 0.97 [0.009300254613126845, 0.6202209065664247] 0.03550561428055964 0.06106456387024086 SBS58 Skin-Melanoma H3K4me1-human ['ENCFF772YVC_foreskin-fibroblast_Normal_H3K4me1-human'] [1.034] 1.034 [0.1536265292973605] 0.15362652929736048 0.22218808628494993 SBS58 Skin-Melanoma H3K9me3-human ['ENCFF342TCS_foreskin-fibroblast_Normal_H3K9me3-human', 'ENCFF849GBJ_foreskin-melanocyte_Normal_H3K9me3-human'] [1.033, 1.0] 1.016 [0.13617697018271052, 0.991098068901386] 0.4052642398382585 0.5048697689153889