# Only cancer types with minimum 2000 mutations for SBS signatures with average probability at least 0.75 are considered. signature cancer_type processive_group_length number_of_processive_groups log10_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_number_of_processive_groups SBS57 Kidney-RCC 2 72 4.277 0.48 1.0 5.0 1.403 0.75 0.0 0.0 inf [1, 2, 1, 5, 1, 1, 1, 3, 2, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 2, 3, 2, 2, 1, 1, 1, 1, 2, 1, 2, 2, 1, 2, 1, 1, 1, 1, 1, 3, 1, 1, 1, 1, 1, 2, 3, 1, 1, 1, 1, 1, 1, 1, 2, 1, 1, 2, 2] SBS57 Kidney-RCC 3 7 1.946 0.218 inf [] SBS57 Stomach-AdenoCA 2 596 6.39 0.48 30.0 74.0 47.65 7.272 0.0 0.0 inf [41, 48, 45, 50, 43, 60, 43, 74, 54, 57, 60, 58, 48, 40, 44, 47, 43, 43, 39, 41, 45, 49, 51, 46, 52, 46, 52, 52, 48, 44, 42, 40, 47, 45, 53, 34, 64, 51, 41, 46, 50, 34, 52, 54, 55, 43, 50, 37, 41, 65, 30, 42, 50, 33, 41, 44, 46, 58, 47, 54, 55, 53, 37, 44, 47, 51, 42, 49, 49, 42, 53, 52, 56, 50, 40, 61, 41, 47, 50, 45, 58, 36, 42, 54, 51, 42, 51, 36, 47, 41, 42, 43, 49, 52, 50, 49, 48, 54, 50, 54] SBS57 Stomach-AdenoCA 3 20 2.996 0.225 1.0 2.0 1.13 0.337 0.0 0.0 inf [1, 1, 1, 1, 1, 1, 1, 1, 1, 2, 1, 1, 1, 2, 1, 1, 2, 1, 1, 1, 1, 1, 1] SBS57 Stomach-AdenoCA 4 2 0.693 0.052 inf [] SBS57 Stomach-AdenoCA 5 2 0.693 0.052 inf [] SBS57 Eye-Melanoma 2 113 4.727 0.48 51.0 82.0 65.16 6.72 9.041425247326428e-13 1.1301781559158036e-12 11.947 [60, 56, 65, 69, 66, 69, 55, 64, 68, 57, 61, 64, 62, 66, 69, 68, 59, 63, 64, 52, 70, 52, 73, 65, 64, 64, 65, 60, 51, 66, 74, 63, 70, 73, 59, 52, 61, 70, 67, 62, 60, 63, 60, 74, 69, 62, 58, 60, 75, 66, 74, 64, 65, 79, 61, 56, 70, 73, 68, 67, 68, 71, 53, 76, 56, 71, 64, 73, 66, 55, 77, 58, 69, 71, 71, 73, 59, 65, 55, 66, 63, 58, 73, 71, 65, 82, 71, 68, 76, 59, 60, 70, 67, 70, 54, 75, 74, 61, 65, 55] SBS57 Eye-Melanoma 3 7 1.946 0.198 1.0 5.0 2.435 1.313 0.00029160138093224766 0.00029160138093224766 3.535 [2, 1, 3, 4, 1, 5, 1, 2, 2, 2, 1, 2, 5, 4, 5, 2, 2, 5, 5, 5, 1, 5, 1, 5, 2, 3, 3, 5, 4, 3, 2, 2, 4, 4, 2, 3, 1, 3, 2, 4, 2, 3, 3, 2, 2, 3, 1, 1, 1, 3, 1, 1, 1, 1, 4, 2, 2, 1, 2, 5, 4, 2, 2, 3, 1, 3, 1, 1, 2, 1, 2, 2, 1, 2, 1, 2, 1, 1, 2, 4, 1, 1, 2, 2, 1, 3, 2, 4, 4, 1, 3, 3] signature cancer_type processive_group_length avg_number_of_processive_groups log10_avg_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_avg_number_of_processive_groups SBS57 ACROSS_ALL_CANCER_TYPES 2 260.333 2.416 0.48 29.0 47.0 38.071 3.451 0.0 0.0 inf [34.0, 35.333, 37.0, 41.333, 36.667, 43.333, 33.0, 47.0, 41.333, 38.333, 40.667, 41.0, 37.0, 35.667, 38.0, 38.667, 34.333, 35.667, 34.667, 31.333, 38.667, 34.0, 41.667, 37.667, 39.667, 37.333, 39.667, 37.667, 33.333, 37.0, 39.0, 35.0, 39.333, 40.0, 38.0, 29.0, 42.333, 40.667, 36.333, 36.333, 37.0, 32.667, 38.333, 43.0, 41.667, 35.333, 36.333, 32.667, 39.333, 44.667, 35.0, 35.667, 38.667, 37.667, 34.333, 33.667, 39.0, 44.333, 38.667, 40.667, 41.667, 42.0, 30.468, 40.468, 34.801, 41.134, 35.801, 41.134, 38.801, 32.801, 43.801, 37.134, 42.134, 40.801, 37.468, 45.134, 33.801, 37.801, 35.468, 37.468, 40.801, 31.801, 38.801, 42.134, 39.134, 41.801, 41.134, 35.134, 41.468, 33.801, 34.468, 38.134, 39.134, 41.134, 35.134, 41.801, 41.134, 38.801, 38.801, 36.801] SBS57 ACROSS_ALL_CANCER_TYPES 3 11.333 1.054 0.21 0.667 2.043 1.188 0.422 1.0112605858125997e-125 1.0112605858125997e-125 124.995 [1.0, 0.667, 1.333, 1.667, 0.667, 2.0, 0.667, 1.0, 1.0, 1.333, 0.667, 1.0, 2.0, 2.0, 2.0, 1.0, 1.333, 2.0, 2.0, 2.0, 0.667, 2.0, 0.667, 2.043, 1.043, 1.377, 1.377, 2.043, 1.71, 1.377, 1.043, 1.043, 1.71, 1.71, 1.043, 1.377, 0.71, 1.377, 1.043, 1.71, 1.043, 1.377, 1.377, 1.043, 1.043, 1.377, 0.71, 0.71, 0.71, 1.377, 0.71, 0.71, 0.71, 0.71, 1.71, 1.043, 1.043, 0.71, 1.043, 2.043, 1.71, 1.043, 1.043, 1.377, 0.71, 1.377, 0.71, 0.71, 1.043, 0.71, 1.043, 1.043, 0.71, 1.043, 0.71, 1.043, 0.71, 0.71, 1.043, 1.71, 0.71, 0.71, 1.043, 1.043, 0.71, 1.377, 1.043, 1.71, 1.71, 0.71, 1.377, 1.377, 1.188, 1.188, 1.188, 1.188, 1.188, 1.188, 1.188, 1.188] SBS57 ACROSS_ALL_CANCER_TYPES 4 2.0 0.301 0.06 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS57 ACROSS_ALL_CANCER_TYPES 5 2.0 0.301 0.06 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]