# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. # For real mutations on transcribed:T, untranscribed:U, bitranscribed:B and nontranscribed:N strands averaged across cancer types. MutationType Across_All_Cancer_Types T:A[C>A]A 4557.0 U:A[C>A]A 2657.667 B:A[C>A]A 35.167 N:A[C>A]A 18697.167 T:A[C>A]C 2848.333 U:A[C>A]C 1698.333 B:A[C>A]C 18.167 N:A[C>A]C 11094.5 T:A[C>A]G 1367.333 U:A[C>A]G 725.167 B:A[C>A]G 7.167 N:A[C>A]G 4509.5 T:A[C>A]T 2898.833 U:A[C>A]T 1846.333 B:A[C>A]T 21.333 N:A[C>A]T 12731.0 T:A[C>G]A 728.5 U:A[C>G]A 460.5 B:A[C>G]A 3.0 N:A[C>G]A 3051.0 T:A[C>G]C 274.167 U:A[C>G]C 194.5 B:A[C>G]C 1.0 N:A[C>G]C 1113.0 T:A[C>G]G 167.5 U:A[C>G]G 116.167 B:A[C>G]G 0.333 N:A[C>G]G 606.167 T:A[C>G]T 307.333 U:A[C>G]T 274.5 B:A[C>G]T 1.5 N:A[C>G]T 1444.167 T:A[C>T]A 582.5 U:A[C>T]A 474.167 B:A[C>T]A 2.167 N:A[C>T]A 2432.667 T:A[C>T]C 251.5 U:A[C>T]C 225.667 B:A[C>T]C 0.167 N:A[C>T]C 1028.833 T:A[C>T]G 88.333 U:A[C>T]G 73.5 B:A[C>T]G 0.167 N:A[C>T]G 311.167 T:A[C>T]T 277.833 U:A[C>T]T 226.167 B:A[C>T]T 1.0 N:A[C>T]T 1173.833 T:A[T>A]A 973.333 U:A[T>A]A 624.333 B:A[T>A]A 4.0 N:A[T>A]A 3878.5 T:A[T>A]C 279.333 U:A[T>A]C 161.5 B:A[T>A]C 0.667 N:A[T>A]C 1009.667 T:A[T>A]G 979.5 U:A[T>A]G 654.5 B:A[T>A]G 5.333 N:A[T>A]G 3807.5 T:A[T>A]T 480.833 U:A[T>A]T 363.5 B:A[T>A]T 0.833 N:A[T>A]T 2077.667 T:A[T>C]A 726.667 U:A[T>C]A 388.0 B:A[T>C]A 1.667 N:A[T>C]A 2283.333 T:A[T>C]C 34.333 U:A[T>C]C 18.667 B:A[T>C]C 0.0 N:A[T>C]C 139.833 T:A[T>C]G 357.167 U:A[T>C]G 214.167 B:A[T>C]G 0.833 N:A[T>C]G 1185.5 T:A[T>C]T 90.5 U:A[T>C]T 49.5 B:A[T>C]T 0.0 N:A[T>C]T 320.333 T:A[T>G]A 83.5 U:A[T>G]A 68.833 B:A[T>G]A 0.0 N:A[T>G]A 394.5 T:A[T>G]C 3.333 U:A[T>G]C 2.167 B:A[T>G]C 0.0 N:A[T>G]C 27.5 T:A[T>G]G 66.167 U:A[T>G]G 44.333 B:A[T>G]G 0.333 N:A[T>G]G 292.167 T:A[T>G]T 6.0 U:A[T>G]T 7.833 B:A[T>G]T 0.0 N:A[T>G]T 52.5 T:C[C>A]A 6843.5 U:C[C>A]A 3965.667 B:C[C>A]A 60.333 N:C[C>A]A 27369.167 T:C[C>A]C 6194.833 U:C[C>A]C 3456.0 B:C[C>A]C 53.333 N:C[C>A]C 22435.833 T:C[C>A]G 1795.167 U:C[C>A]G 971.5 B:C[C>A]G 18.667 N:C[C>A]G 5273.167 T:C[C>A]T 5335.167 U:C[C>A]T 3353.333 B:C[C>A]T 39.667 N:C[C>A]T 21994.667 T:C[C>G]A 709.0 U:C[C>G]A 493.167 B:C[C>G]A 5.167 N:C[C>G]A 2864.333 T:C[C>G]C 514.0 U:C[C>G]C 376.0 B:C[C>G]C 4.667 N:C[C>G]C 1953.833 T:C[C>G]G 290.167 U:C[C>G]G 236.833 B:C[C>G]G 1.833 N:C[C>G]G 985.833 T:C[C>G]T 515.5 U:C[C>G]T 490.667 B:C[C>G]T 2.167 N:C[C>G]T 2201.0 T:C[C>T]A 1033.0 U:C[C>T]A 1166.833 B:C[C>T]A 10.333 N:C[C>T]A 4581.167 T:C[C>T]C 784.833 U:C[C>T]C 886.833 B:C[C>T]C 7.5 N:C[C>T]C 3196.167 T:C[C>T]G 182.833 U:C[C>T]G 213.667 B:C[C>T]G 1.333 N:C[C>T]G 599.0 T:C[C>T]T 1221.0 U:C[C>T]T 1195.5 B:C[C>T]T 12.333 N:C[C>T]T 5257.833 T:C[T>A]A 1452.667 U:C[T>A]A 880.5 B:C[T>A]A 5.833 N:C[T>A]A 5639.833 T:C[T>A]C 1027.833 U:C[T>A]C 670.833 B:C[T>A]C 5.667 N:C[T>A]C 3758.833 T:C[T>A]G 2701.0 U:C[T>A]G 1796.333 B:C[T>A]G 23.333 N:C[T>A]G 9784.833 T:C[T>A]T 1195.667 U:C[T>A]T 883.833 B:C[T>A]T 8.667 N:C[T>A]T 5082.833 T:C[T>C]A 526.167 U:C[T>C]A 342.333 B:C[T>C]A 2.167 N:C[T>C]A 1898.5 T:C[T>C]C 158.0 U:C[T>C]C 123.5 B:C[T>C]C 0.0 N:C[T>C]C 632.5 T:C[T>C]G 367.833 U:C[T>C]G 269.833 B:C[T>C]G 1.333 N:C[T>C]G 1331.833 T:C[T>C]T 190.5 U:C[T>C]T 157.333 B:C[T>C]T 0.167 N:C[T>C]T 815.5 T:C[T>G]A 75.833 U:C[T>G]A 51.667 B:C[T>G]A 0.333 N:C[T>G]A 306.667 T:C[T>G]C 19.0 U:C[T>G]C 14.667 B:C[T>G]C 0.0 N:C[T>G]C 86.333 T:C[T>G]G 276.167 U:C[T>G]G 200.667 B:C[T>G]G 2.0 N:C[T>G]G 984.833 T:C[T>G]T 74.667 U:C[T>G]T 74.833 B:C[T>G]T 0.0 N:C[T>G]T 344.167 T:G[C>A]A 3179.167 U:G[C>A]A 1945.667 B:G[C>A]A 28.167 N:G[C>A]A 12667.167 T:G[C>A]C 3083.167 U:G[C>A]C 1736.167 B:G[C>A]C 24.5 N:G[C>A]C 11040.167 T:G[C>A]G 1300.5 U:G[C>A]G 721.667 B:G[C>A]G 13.0 N:G[C>A]G 3819.167 T:G[C>A]T 2014.833 U:G[C>A]T 1360.333 B:G[C>A]T 17.667 N:G[C>A]T 8590.833 T:G[C>G]A 511.167 U:G[C>G]A 353.833 B:G[C>G]A 2.167 N:G[C>G]A 2152.5 T:G[C>G]C 467.333 U:G[C>G]C 387.333 B:G[C>G]C 2.667 N:G[C>G]C 1844.5 T:G[C>G]G 272.0 U:G[C>G]G 193.167 B:G[C>G]G 3.167 N:G[C>G]G 924.833 T:G[C>G]T 239.833 U:G[C>G]T 212.333 B:G[C>G]T 1.333 N:G[C>G]T 1099.833 T:G[C>T]A 307.833 U:G[C>T]A 284.333 B:G[C>T]A 1.167 N:G[C>T]A 1247.333 T:G[C>T]C 264.833 U:G[C>T]C 248.167 B:G[C>T]C 0.833 N:G[C>T]C 984.833 T:G[C>T]G 30.5 U:G[C>T]G 30.167 B:G[C>T]G 0.0 N:G[C>T]G 111.5 T:G[C>T]T 263.167 U:G[C>T]T 244.667 B:G[C>T]T 1.0 N:G[C>T]T 1119.0 T:G[T>A]A 862.167 U:G[T>A]A 573.833 B:G[T>A]A 4.667 N:G[T>A]A 3353.0 T:G[T>A]C 306.5 U:G[T>A]C 219.0 B:G[T>A]C 1.667 N:G[T>A]C 1160.0 T:G[T>A]G 1127.333 U:G[T>A]G 820.833 B:G[T>A]G 7.5 N:G[T>A]G 4332.0 T:G[T>A]T 511.0 U:G[T>A]T 388.5 B:G[T>A]T 1.833 N:G[T>A]T 2204.167 T:G[T>C]A 298.833 U:G[T>C]A 208.833 B:G[T>C]A 0.833 N:G[T>C]A 1086.167 T:G[T>C]C 70.167 U:G[T>C]C 51.167 B:G[T>C]C 0.0 N:G[T>C]C 271.167 T:G[T>C]G 172.667 U:G[T>C]G 138.167 B:G[T>C]G 0.0 N:G[T>C]G 670.833 T:G[T>C]T 50.833 U:G[T>C]T 41.0 B:G[T>C]T 0.0 N:G[T>C]T 238.167 T:G[T>G]A 38.333 U:G[T>G]A 30.5 B:G[T>G]A 0.0 N:G[T>G]A 170.167 T:G[T>G]C 9.667 U:G[T>G]C 10.5 B:G[T>G]C 0.0 N:G[T>G]C 61.167 T:G[T>G]G 196.5 U:G[T>G]G 178.833 B:G[T>G]G 1.0 N:G[T>G]G 718.167 T:G[T>G]T 17.667 U:G[T>G]T 22.167 B:G[T>G]T 0.0 N:G[T>G]T 114.667 T:T[C>A]A 3684.667 U:T[C>A]A 2442.833 B:T[C>A]A 27.333 N:T[C>A]A 15396.5 T:T[C>A]C 4265.167 U:T[C>A]C 2633.167 B:T[C>A]C 38.167 N:T[C>A]C 16445.5 T:T[C>A]G 777.333 U:T[C>A]G 470.333 B:T[C>A]G 3.5 N:T[C>A]G 2578.167 T:T[C>A]T 3657.833 U:T[C>A]T 2693.333 B:T[C>A]T 32.0 N:T[C>A]T 16570.5 T:T[C>G]A 415.5 U:T[C>G]A 335.0 B:T[C>G]A 1.5 N:T[C>G]A 1654.667 T:T[C>G]C 569.833 U:T[C>G]C 471.5 B:T[C>G]C 3.5 N:T[C>G]C 2157.5 T:T[C>G]G 140.167 U:T[C>G]G 118.0 B:T[C>G]G 0.5 N:T[C>G]G 543.5 T:T[C>G]T 361.0 U:T[C>G]T 388.0 B:T[C>G]T 1.667 N:T[C>G]T 1580.667 T:T[C>T]A 369.0 U:T[C>T]A 374.667 B:T[C>T]A 1.333 N:T[C>T]A 1480.333 T:T[C>T]C 510.5 U:T[C>T]C 531.333 B:T[C>T]C 2.333 N:T[C>T]C 2029.833 T:T[C>T]G 8.0 U:T[C>T]G 8.5 B:T[C>T]G 0.0 N:T[C>T]G 41.0 T:T[C>T]T 624.333 U:T[C>T]T 662.667 B:T[C>T]T 4.0 N:T[C>T]T 2675.5 T:T[T>A]A 966.0 U:T[T>A]A 726.5 B:T[T>A]A 4.833 N:T[T>A]A 3860.5 T:T[T>A]C 390.0 U:T[T>A]C 287.5 B:T[T>A]C 1.167 N:T[T>A]C 1627.5 T:T[T>A]G 733.333 U:T[T>A]G 621.833 B:T[T>A]G 3.0 N:T[T>A]G 3310.0 T:T[T>A]T 507.5 U:T[T>A]T 442.167 B:T[T>A]T 3.167 N:T[T>A]T 2326.0 T:T[T>C]A 214.0 U:T[T>C]A 158.833 B:T[T>C]A 0.167 N:T[T>C]A 832.5 T:T[T>C]C 25.167 U:T[T>C]C 21.833 B:T[T>C]C 0.0 N:T[T>C]C 140.333 T:T[T>C]G 111.833 U:T[T>C]G 111.167 B:T[T>C]G 0.333 N:T[T>C]G 543.167 T:T[T>C]T 33.667 U:T[T>C]T 30.0 B:T[T>C]T 0.0 N:T[T>C]T 174.833 T:T[T>G]A 25.667 U:T[T>G]A 23.667 B:T[T>G]A 0.0 N:T[T>G]A 131.833 T:T[T>G]C 1.5 U:T[T>G]C 1.5 B:T[T>G]C 0.0 N:T[T>G]C 19.667 T:T[T>G]G 137.333 U:T[T>G]G 131.167 B:T[T>G]G 0.0 N:T[T>G]G 671.5 T:T[T>G]T 21.167 U:T[T>G]T 29.5 B:T[T>G]T 0.0 N:T[T>G]T 127.333 # There must be at least 1000 mutations on the strands. # Signature and mutation type must have at least 5% of all signature mutations on the strands. # Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1. cancer_type signature mutation_type Transcribed_real_count UnTranscribed_real_count NonTranscribed_real_count Transcribed_mean_sims_count UnTranscribed_mean_sims_count NonTranscribed_mean_sims_count transcribed_versus_untranscribed_p_value transcribed_versus_untranscribed_q_value percentage_of_mutations_on_strands signature_number_of_mutations_on_strands significant_strand FC_REAL FC_SIMS FC fold_change_1.1 fold_change_1.2 fold_change_1.3 fold_change_1.5 fold_change_1.75 fold_change_2+ Transcribed_real_count.1 Transcribed_mean_sims_count.1 Transcribed_min_sims_count Transcribed_max_sims_count Transcribed_sims_count_list UnTranscribed_real_count.1 UnTranscribed_mean_sims_count.1 UnTranscribed_min_sims_count UnTranscribed_max_sims_count UnTranscribed_sims_count_list NonTranscribed_real_count.1 NonTranscribed_mean_sims_count.1 NonTranscribed_min_sims_count NonTranscribed_max_sims_count NonTranscribed_sims_count_list ESCC SBS4 C>A 2000.0 1552.0 8040.0 2618.01 2497.31 6510.28 2.7971484282368285e-06 1.4335861400228752e-05 84.177 13771.0 Transcribed 1.289 1.048 1.229 1 1 2000.0 2618.01 2531.0 2738.0 [2592, 2638, 2531, 2615, 2617, 2590, 2686, 2650, 2583, 2617, 2623, 2661, 2642, 2696, 2624, 2601, 2682, 2662, 2628, 2648, 2574, 2571, 2586, 2620, 2666, 2657, 2622, 2635, 2714, 2628, 2581, 2655, 2646, 2622, 2557, 2609, 2617, 2566, 2715, 2589, 2722, 2548, 2565, 2648, 2602, 2671, 2644, 2615, 2712, 2641, 2643, 2592, 2620, 2691, 2607, 2578, 2738, 2620, 2585, 2594, 2547, 2569, 2596, 2566, 2582, 2636, 2625, 2614, 2606, 2637, 2656, 2689, 2603, 2668, 2565, 2576, 2621, 2589, 2618, 2651, 2596, 2587, 2574, 2634, 2619, 2536, 2621, 2576, 2545, 2651, 2641, 2578, 2581, 2582, 2657, 2601, 2591, 2584, 2619, 2562] 1552.0 2497.31 2385.0 2601.0 [2457, 2419, 2495, 2487, 2522, 2470, 2487, 2456, 2500, 2496, 2531, 2494, 2484, 2385, 2485, 2386, 2484, 2536, 2534, 2465, 2536, 2473, 2460, 2478, 2524, 2450, 2537, 2465, 2539, 2525, 2523, 2455, 2576, 2521, 2446, 2477, 2513, 2582, 2513, 2517, 2458, 2484, 2456, 2502, 2426, 2493, 2479, 2537, 2504, 2466, 2505, 2546, 2513, 2555, 2423, 2534, 2492, 2559, 2495, 2482, 2549, 2512, 2546, 2558, 2550, 2507, 2488, 2588, 2506, 2534, 2472, 2462, 2496, 2432, 2511, 2445, 2489, 2487, 2396, 2519, 2508, 2601, 2507, 2440, 2522, 2454, 2545, 2450, 2492, 2482, 2516, 2489, 2530, 2518, 2496, 2469, 2566, 2430, 2537, 2540] 8040.0 6510.28 6365.0 6642.0 [6574, 6563, 6603, 6526, 6483, 6561, 6450, 6522, 6542, 6508, 6477, 6482, 6496, 6533, 6515, 6625, 6455, 6437, 6460, 6518, 6521, 6580, 6583, 6520, 6428, 6533, 6469, 6528, 6365, 6479, 6519, 6512, 6411, 6477, 6618, 6533, 6512, 6482, 6404, 6516, 6444, 6599, 6596, 6478, 6601, 6449, 6487, 6483, 6405, 6516, 6480, 6494, 6499, 6383, 6589, 6506, 6388, 6455, 6547, 6541, 6534, 6544, 6486, 6501, 6502, 6497, 6509, 6435, 6508, 6460, 6506, 6479, 6532, 6526, 6539, 6607, 6516, 6548, 6595, 6451, 6521, 6445, 6546, 6566, 6474, 6642, 6459, 6596, 6598, 6488, 6463, 6558, 6513, 6516, 6472, 6564, 6467, 6616, 6475, 6514] ESCC SBS4 C>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 13771.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS4 C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 13771.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS4 T>A 364.0 293.0 1522.0 470.56 471.37 1244.04 0.032667510067212364 0.10734967469309885 15.823 13771.0 Transcribed 1.242 0.998 1.244 1 1 364.0 470.56 412.0 534.0 [463, 465, 466, 479, 498, 460, 447, 483, 493, 458, 475, 494, 429, 463, 412, 467, 454, 500, 470, 458, 498, 442, 477, 488, 502, 467, 470, 495, 498, 498, 477, 502, 488, 451, 483, 468, 478, 449, 464, 467, 447, 464, 473, 482, 488, 467, 515, 484, 479, 447, 455, 534, 479, 458, 462, 476, 487, 488, 443, 459, 456, 454, 446, 465, 498, 465, 460, 490, 455, 460, 468, 483, 472, 473, 468, 447, 447, 464, 471, 474, 450, 465, 452, 458, 497, 474, 449, 480, 494, 474, 437, 495, 466, 483, 479, 466, 480, 442, 436, 480] 293.0 471.37 419.0 518.0 [492, 489, 477, 466, 476, 487, 484, 495, 446, 460, 461, 509, 488, 486, 518, 494, 498, 475, 498, 464, 467, 468, 448, 482, 446, 496, 497, 491, 419, 454, 445, 496, 492, 482, 447, 454, 482, 455, 468, 469, 514, 481, 461, 500, 465, 466, 464, 468, 470, 458, 460, 447, 458, 471, 455, 465, 452, 482, 509, 475, 465, 497, 476, 463, 452, 491, 454, 441, 472, 481, 453, 495, 458, 485, 461, 465, 460, 467, 432, 427, 468, 483, 505, 469, 478, 460, 505, 458, 475, 452, 501, 469, 473, 451, 478, 493, 466, 449, 425, 442] 1522.0 1244.04 1180.0 1323.0 [1235, 1232, 1241, 1243, 1209, 1246, 1254, 1210, 1250, 1268, 1253, 1180, 1272, 1237, 1258, 1224, 1233, 1208, 1219, 1264, 1220, 1275, 1261, 1214, 1236, 1220, 1221, 1195, 1272, 1241, 1259, 1199, 1210, 1250, 1258, 1265, 1223, 1279, 1250, 1251, 1224, 1236, 1250, 1206, 1236, 1252, 1215, 1232, 1240, 1280, 1268, 1209, 1255, 1259, 1268, 1243, 1246, 1210, 1231, 1260, 1259, 1235, 1258, 1256, 1240, 1230, 1270, 1256, 1258, 1241, 1267, 1210, 1257, 1224, 1257, 1275, 1275, 1259, 1281, 1284, 1269, 1236, 1227, 1263, 1209, 1249, 1236, 1247, 1218, 1260, 1248, 1221, 1246, 1250, 1234, 1223, 1243, 1294, 1323, 1261] ESCC SBS4 T>C 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 13771.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS4 T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 13771.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Head-SCC SBS4 C>A 12722.0 9282.0 55061.0 17215.8 16455.01 43619.33 4.0865816816447146e-54 5.35138581509466e-53 70.774 108889.0 Transcribed 1.371 1.046 1.31 1 1 1 12722.0 17215.8 16927.0 17474.0 [17073, 17130, 17299, 17208, 17392, 17115, 17098, 17194, 17056, 17083, 17250, 16927, 17296, 17224, 17431, 17231, 17032, 17105, 17302, 17088, 17227, 17315, 17274, 17246, 17369, 17310, 17152, 17348, 17127, 17263, 17114, 17244, 17155, 17281, 17394, 17138, 17182, 17263, 17231, 17113, 17388, 17045, 17302, 17177, 17235, 16939, 17366, 17066, 17179, 17218, 17277, 17041, 17401, 17290, 17293, 17235, 17250, 17113, 17189, 17360, 17045, 17231, 17215, 17250, 17237, 17063, 17047, 17347, 17180, 17318, 17233, 17104, 17020, 17089, 17286, 17265, 17136, 17289, 17206, 17364, 17268, 17228, 17474, 17270, 17311, 17147, 17218, 17173, 17292, 17122, 17250, 17226, 17313, 17424, 17127, 17414, 17179, 17139, 17119, 17317] 9282.0 16455.01 16196.0 16742.0 [16474, 16495, 16553, 16427, 16590, 16506, 16484, 16459, 16443, 16447, 16439, 16536, 16369, 16265, 16295, 16551, 16582, 16629, 16245, 16299, 16555, 16428, 16400, 16273, 16522, 16403, 16563, 16371, 16503, 16421, 16415, 16430, 16470, 16547, 16365, 16551, 16588, 16422, 16521, 16469, 16465, 16550, 16196, 16580, 16302, 16475, 16502, 16444, 16544, 16565, 16463, 16529, 16211, 16328, 16383, 16531, 16356, 16516, 16464, 16567, 16480, 16238, 16272, 16519, 16239, 16440, 16696, 16382, 16583, 16488, 16537, 16598, 16423, 16612, 16556, 16550, 16367, 16220, 16534, 16397, 16300, 16323, 16302, 16510, 16578, 16575, 16313, 16435, 16596, 16742, 16342, 16379, 16496, 16378, 16379, 16573, 16564, 16516, 16410, 16383] 55061.0 43619.33 43323.0 43905.0 [43769, 43626, 43452, 43663, 43330, 43636, 43699, 43644, 43788, 43742, 43587, 43810, 43604, 43783, 43543, 43529, 43680, 43556, 43735, 43905, 43503, 43569, 43628, 43770, 43409, 43563, 43583, 43589, 43642, 43619, 43733, 43615, 43673, 43433, 43527, 43579, 43509, 43627, 43542, 43700, 43464, 43701, 43824, 43549, 43749, 43902, 43438, 43754, 43580, 43514, 43573, 43707, 43648, 43672, 43613, 43520, 43687, 43670, 43651, 43360, 43743, 43826, 43795, 43499, 43833, 43740, 43573, 43551, 43507, 43477, 43516, 43574, 43829, 43614, 43443, 43504, 43778, 43781, 43541, 43518, 43732, 43734, 43524, 43523, 43421, 43602, 43737, 43721, 43372, 43442, 43690, 43686, 43499, 43501, 43788, 43323, 43537, 43626, 43753, 43610] Head-SCC SBS4 C>G 1046.0 850.0 4232.0 1421.91 1369.81 3358.07 0.0046293891109874365 0.017686520061957072 5.628 108889.0 Transcribed 1.231 1.038 1.185 1 1046.0 1421.91 1354.0 1484.0 [1411, 1420, 1412, 1458, 1405, 1483, 1403, 1377, 1448, 1419, 1484, 1380, 1410, 1436, 1389, 1418, 1446, 1405, 1454, 1407, 1423, 1436, 1463, 1450, 1408, 1373, 1481, 1367, 1465, 1408, 1400, 1378, 1384, 1370, 1438, 1455, 1363, 1449, 1457, 1355, 1466, 1449, 1418, 1484, 1439, 1373, 1432, 1368, 1433, 1432, 1415, 1354, 1408, 1470, 1359, 1448, 1453, 1447, 1425, 1456, 1441, 1380, 1457, 1451, 1376, 1390, 1385, 1412, 1427, 1416, 1470, 1370, 1436, 1362, 1401, 1374, 1417, 1478, 1403, 1465, 1458, 1432, 1448, 1417, 1433, 1410, 1408, 1444, 1388, 1415, 1388, 1465, 1410, 1439, 1474, 1423, 1445, 1421, 1446, 1399] 850.0 1369.81 1294.0 1454.0 [1342, 1377, 1368, 1397, 1354, 1310, 1376, 1342, 1394, 1356, 1364, 1393, 1398, 1387, 1295, 1355, 1351, 1375, 1320, 1396, 1326, 1415, 1383, 1373, 1337, 1454, 1340, 1402, 1418, 1362, 1349, 1377, 1374, 1396, 1343, 1374, 1383, 1343, 1435, 1396, 1328, 1406, 1387, 1294, 1427, 1369, 1349, 1378, 1407, 1336, 1379, 1359, 1336, 1409, 1348, 1325, 1364, 1355, 1391, 1370, 1326, 1379, 1318, 1371, 1406, 1390, 1369, 1377, 1388, 1302, 1373, 1376, 1404, 1411, 1410, 1411, 1401, 1405, 1382, 1350, 1365, 1435, 1368, 1399, 1336, 1408, 1385, 1364, 1360, 1362, 1332, 1346, 1378, 1381, 1308, 1358, 1310, 1335, 1397, 1358] 4232.0 3358.07 3259.0 3460.0 [3398, 3349, 3356, 3303, 3388, 3352, 3372, 3424, 3314, 3381, 3302, 3382, 3336, 3327, 3460, 3383, 3351, 3372, 3368, 3338, 3396, 3303, 3303, 3341, 3397, 3324, 3332, 3384, 3271, 3379, 3401, 3391, 3389, 3397, 3364, 3317, 3406, 3358, 3259, 3405, 3359, 3299, 3339, 3376, 3279, 3407, 3367, 3396, 3308, 3375, 3363, 3442, 3412, 3274, 3433, 3376, 3340, 3345, 3334, 3332, 3391, 3395, 3372, 3334, 3361, 3375, 3396, 3359, 3337, 3424, 3309, 3406, 3312, 3373, 3343, 3362, 3329, 3261, 3375, 3336, 3323, 3284, 3331, 3338, 3377, 3333, 3350, 3343, 3404, 3382, 3428, 3334, 3362, 3341, 3369, 3365, 3392, 3382, 3304, 3386] Head-SCC SBS4 C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 108889.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Head-SCC SBS4 T>A 4152.0 3403.0 18141.0 5321.92 5630.7 14827.23 1.6634075171110224e-17 1.3127212535524904e-16 23.598 108889.0 Transcribed 1.22 0.945 1.291 1 1 4152.0 5321.92 5210.0 5490.0 [5326, 5357, 5353, 5413, 5387, 5237, 5273, 5241, 5299, 5258, 5355, 5302, 5369, 5264, 5272, 5285, 5377, 5297, 5259, 5257, 5276, 5406, 5275, 5402, 5284, 5382, 5362, 5349, 5283, 5366, 5302, 5441, 5366, 5313, 5216, 5390, 5298, 5358, 5335, 5234, 5293, 5331, 5266, 5269, 5348, 5265, 5345, 5346, 5258, 5349, 5329, 5365, 5253, 5322, 5286, 5359, 5213, 5398, 5375, 5461, 5328, 5350, 5293, 5375, 5267, 5335, 5320, 5342, 5356, 5431, 5338, 5358, 5377, 5268, 5401, 5287, 5224, 5246, 5339, 5266, 5302, 5294, 5308, 5241, 5481, 5344, 5321, 5270, 5403, 5490, 5261, 5362, 5443, 5258, 5247, 5269, 5325, 5210, 5258, 5354] 3403.0 5630.7 5465.0 5777.0 [5650, 5465, 5665, 5584, 5572, 5643, 5543, 5669, 5564, 5672, 5644, 5702, 5597, 5680, 5616, 5598, 5777, 5627, 5612, 5695, 5671, 5712, 5739, 5580, 5624, 5639, 5566, 5640, 5684, 5646, 5589, 5640, 5642, 5557, 5689, 5640, 5572, 5472, 5600, 5632, 5649, 5567, 5703, 5684, 5593, 5574, 5604, 5652, 5700, 5681, 5561, 5675, 5706, 5584, 5613, 5592, 5747, 5599, 5647, 5574, 5570, 5497, 5656, 5531, 5690, 5591, 5605, 5734, 5653, 5568, 5627, 5560, 5616, 5684, 5619, 5658, 5655, 5599, 5759, 5674, 5610, 5672, 5653, 5579, 5626, 5670, 5597, 5644, 5687, 5588, 5615, 5524, 5565, 5630, 5660, 5771, 5669, 5733, 5591, 5626] 18141.0 14827.23 14655.0 14986.0 [14814, 14955, 14767, 14774, 14803, 14885, 14986, 14864, 14929, 14839, 14770, 14771, 14811, 14829, 14885, 14899, 14668, 14857, 14900, 14836, 14839, 14655, 14775, 14796, 14870, 14753, 14848, 14795, 14802, 14754, 14870, 14709, 14765, 14911, 14871, 14758, 14911, 14956, 14845, 14898, 14840, 14876, 14796, 14815, 14847, 14938, 14826, 14782, 14801, 14760, 14883, 14729, 14812, 14879, 14869, 14803, 14807, 14785, 14777, 14779, 14893, 14932, 14817, 14878, 14834, 14850, 14868, 14712, 14783, 14778, 14810, 14872, 14778, 14818, 14767, 14846, 14897, 14927, 14690, 14850, 14857, 14823, 14821, 14976, 14674, 14768, 14862, 14888, 14679, 14724, 14899, 14891, 14766, 14879, 14882, 14761, 14793, 14822, 14927, 14804] Head-SCC SBS4 T>C 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 108889.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Head-SCC SBS4 T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 108889.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS4 C>A 16146.0 11844.0 60254.0 19968.79 19150.75 49405.26 5.680701067325148e-65 8.146903903786993e-64 92.59 95306.0 Transcribed 1.363 1.043 1.307 1 1 1 16146.0 19968.79 19636.0 20312.0 [20121, 19844, 20016, 20114, 19945, 19952, 19636, 19905, 19952, 19945, 19824, 19963, 19926, 19768, 19918, 20108, 19795, 19995, 20045, 19868, 19920, 19808, 20024, 19805, 20130, 20260, 19925, 19866, 19896, 20102, 20026, 20018, 19959, 19937, 20059, 19774, 20203, 19957, 19970, 19848, 19805, 20051, 19951, 20241, 19962, 20014, 19697, 19950, 19945, 19746, 19859, 20040, 20164, 19919, 20116, 19970, 20157, 20148, 19669, 19922, 20312, 20014, 20106, 20015, 20034, 19859, 19887, 20034, 19978, 20036, 19787, 19948, 20012, 20069, 20073, 20036, 19817, 20090, 19841, 19896, 20023, 20228, 20026, 19750, 19802, 20081, 19932, 19943, 19912, 20222, 20067, 19855, 19754, 19980, 19879, 19981, 20129, 20005, 19924, 20089] 11844.0 19150.75 18817.0 19434.0 [19040, 19262, 19173, 19149, 19195, 18922, 19126, 19252, 19079, 18978, 19202, 19135, 18944, 19228, 18823, 19074, 19154, 19039, 18982, 19184, 19337, 19233, 18860, 19034, 19050, 19214, 19114, 18983, 19113, 19155, 19204, 19150, 19428, 19132, 19303, 19144, 19060, 19019, 19066, 19253, 19120, 19284, 19342, 19098, 19012, 19251, 19303, 19046, 19157, 19176, 19086, 19220, 19178, 19200, 19102, 19225, 19185, 19150, 19283, 19369, 19126, 18977, 19045, 19195, 19072, 19117, 19197, 18993, 19114, 19287, 19237, 19297, 19264, 18817, 19229, 19324, 19434, 19158, 19098, 19269, 19150, 19102, 19252, 19297, 19136, 19198, 19054, 19107, 19216, 19146, 19058, 19050, 19182, 19091, 19308, 19159, 19411, 19056, 19276, 18996] 60254.0 49405.26 49033.0 49769.0 [49380, 49416, 49305, 49261, 49367, 49660, 49735, 49362, 49491, 49575, 49502, 49475, 49610, 49544, 49769, 49343, 49572, 49460, 49486, 49447, 49294, 49502, 49653, 49658, 49349, 49059, 49512, 49671, 49505, 49279, 49262, 49341, 49126, 49464, 49160, 49593, 49247, 49521, 49512, 49436, 49577, 49217, 49239, 49159, 49536, 49239, 49526, 49491, 49422, 49595, 49597, 49280, 49148, 49398, 49300, 49351, 49186, 49194, 49587, 49237, 49099, 49505, 49345, 49377, 49432, 49573, 49468, 49484, 49424, 49207, 49507, 49283, 49247, 49626, 49222, 49174, 49258, 49322, 49585, 49351, 49360, 49201, 49253, 49508, 49579, 49235, 49564, 49457, 49426, 49177, 49407, 49624, 49591, 49477, 49351, 49435, 49033, 49431, 49288, 49457] Liver-HCC SBS4 C>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 95306.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS4 C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 95306.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS4 T>A 1353.0 1220.0 4489.0 1533.71 1591.66 3944.95 0.008404364644527729 0.03086698890081504 7.41 95306.0 Transcribed 1.109 0.964 1.151 1 1353.0 1533.71 1417.0 1628.0 [1509, 1500, 1508, 1538, 1541, 1522, 1526, 1520, 1499, 1523, 1534, 1572, 1537, 1524, 1574, 1594, 1546, 1515, 1567, 1628, 1573, 1544, 1554, 1500, 1518, 1573, 1567, 1526, 1523, 1500, 1529, 1607, 1550, 1545, 1527, 1574, 1532, 1417, 1461, 1509, 1561, 1503, 1603, 1559, 1516, 1565, 1507, 1500, 1535, 1561, 1564, 1537, 1471, 1579, 1517, 1511, 1458, 1574, 1583, 1558, 1475, 1597, 1573, 1511, 1561, 1562, 1474, 1462, 1504, 1607, 1485, 1536, 1566, 1577, 1553, 1490, 1556, 1452, 1532, 1582, 1571, 1566, 1532, 1570, 1476, 1492, 1536, 1520, 1501, 1553, 1495, 1565, 1540, 1509, 1498, 1547, 1543, 1495, 1468, 1571] 1220.0 1591.66 1484.0 1688.0 [1621, 1583, 1602, 1600, 1666, 1592, 1565, 1619, 1589, 1626, 1542, 1546, 1627, 1635, 1531, 1613, 1647, 1547, 1536, 1599, 1601, 1604, 1563, 1602, 1601, 1565, 1586, 1545, 1558, 1612, 1553, 1513, 1681, 1598, 1592, 1536, 1508, 1600, 1655, 1568, 1601, 1560, 1573, 1598, 1656, 1630, 1671, 1629, 1484, 1585, 1579, 1533, 1617, 1625, 1615, 1637, 1633, 1580, 1517, 1599, 1644, 1557, 1555, 1590, 1577, 1551, 1640, 1628, 1599, 1586, 1600, 1574, 1594, 1591, 1554, 1668, 1515, 1534, 1557, 1586, 1578, 1623, 1577, 1559, 1547, 1606, 1589, 1631, 1645, 1644, 1598, 1554, 1611, 1597, 1688, 1618, 1568, 1538, 1653, 1593] 4489.0 3944.95 3842.0 4075.0 [3932, 3983, 3961, 3943, 3869, 3957, 3982, 3924, 3976, 3936, 3991, 3950, 3911, 3906, 3971, 3871, 3881, 4008, 3974, 3842, 3901, 3925, 3950, 3970, 3943, 3934, 3918, 4012, 3991, 3961, 3973, 3954, 3848, 3928, 3950, 3961, 4020, 4049, 3951, 3993, 3912, 3999, 3895, 3910, 3908, 3876, 3895, 3943, 4053, 3921, 3930, 4004, 3981, 3877, 3940, 3921, 3982, 3912, 3976, 3913, 3960, 3910, 3934, 3973, 3928, 3955, 3955, 3983, 3973, 3872, 3977, 3961, 3905, 3903, 3962, 3901, 4011, 4075, 3982, 3895, 3922, 3892, 3962, 3942, 4042, 3973, 3940, 3911, 3922, 3878, 3983, 3952, 3917, 3967, 3878, 3905, 3959, 4032, 3946, 3909] Liver-HCC SBS4 T>C 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 95306.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS4 T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 95306.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Lung-AdenoCA SBS4 C>A 202324.0 118135.0 780972.0 247638.27 236843.43 620168.96 0.0 0.0 66.487 1656622.0 Transcribed 1.713 1.046 1.638 1 1 1 1 202324.0 247638.27 246350.0 248634.0 [247281, 248046, 247875, 247480, 247412, 247214, 248111, 247902, 247866, 247606, 247628, 248060, 247114, 247401, 247551, 248086, 247673, 247875, 247811, 247518, 247405, 247562, 247345, 247413, 247568, 247527, 247625, 247569, 247670, 248175, 248106, 247799, 248289, 247394, 247697, 247419, 248203, 248368, 247875, 246916, 247791, 246739, 247548, 246693, 248281, 247578, 248224, 247245, 247876, 247125, 247088, 247654, 248323, 248121, 247470, 247204, 247301, 247207, 246850, 247131, 246812, 248634, 247870, 247625, 247444, 247777, 247847, 247425, 248283, 247550, 247949, 247335, 247994, 247647, 248284, 248113, 248151, 247971, 248305, 247388, 247407, 248180, 247765, 247491, 246632, 247643, 247693, 247758, 247925, 248182, 247509, 246848, 247940, 247597, 247465, 247879, 246916, 247493, 246350, 247866] 118135.0 236843.43 236097.0 237878.0 [236979, 236640, 236749, 237236, 236872, 237878, 237443, 236894, 236564, 236946, 236907, 236817, 237329, 236533, 236994, 236301, 237274, 237089, 236485, 237447, 236137, 236421, 236942, 236980, 237177, 236671, 236963, 237339, 236878, 236992, 236306, 236511, 236159, 236441, 236097, 236176, 236598, 236684, 236903, 237135, 236683, 236839, 236945, 236204, 236423, 236850, 237031, 237218, 236898, 236599, 237781, 236641, 236669, 236879, 236670, 237815, 237142, 236517, 237191, 236639, 236623, 237226, 236824, 236884, 236545, 237117, 236769, 236357, 236737, 236248, 236571, 236597, 236638, 237165, 237154, 236434, 237211, 237364, 236572, 237395, 236687, 236670, 236200, 236612, 237149, 236818, 237375, 237157, 237175, 236497, 236886, 237321, 236937, 237030, 237105, 236132, 237379, 236475, 237033, 236753] 780972.0 620168.96 618816.0 621639.0 [620391, 619984, 619934, 620067, 620396, 619535, 619103, 620005, 620274, 619982, 620016, 619771, 620249, 620554, 620121, 620333, 619842, 619715, 620328, 619604, 621172, 620715, 620383, 620219, 619794, 620455, 619928, 619813, 620104, 619613, 620285, 620327, 620262, 620788, 620818, 620952, 619885, 619595, 619747, 620671, 620155, 621081, 620149, 621639, 619996, 620237, 619446, 620280, 619905, 620939, 619819, 620350, 619628, 619678, 620461, 619623, 620231, 620891, 620688, 620838, 621159, 618816, 619923, 620102, 620618, 619854, 620129, 620898, 619591, 620742, 620086, 620749, 619937, 619889, 619301, 620106, 619344, 619481, 619808, 619985, 620620, 619836, 620644, 620390, 620814, 620250, 619658, 619830, 619474, 619970, 620215, 620437, 619708, 619870, 620051, 620743, 620254, 620608, 621188, 620054] Lung-AdenoCA SBS4 C>G 23908.0 16834.0 92740.0 30560.21 29044.44 74262.17 9.632436088596946e-119 1.9097571971444576e-117 8.057 1656622.0 Transcribed 1.42 1.052 1.35 1 1 1 23908.0 30560.21 30122.0 31070.0 [30277, 30535, 30463, 30330, 30461, 30493, 30691, 30494, 30331, 30485, 30400, 30349, 30383, 30680, 30781, 30463, 30677, 30382, 30692, 30584, 30122, 30400, 30275, 30819, 30506, 30910, 30477, 30497, 30620, 30529, 30946, 30673, 30765, 30766, 30246, 30583, 30558, 30605, 30275, 30466, 30579, 30555, 30587, 30443, 30759, 30504, 30400, 30582, 30658, 30364, 30846, 30574, 30808, 30495, 30636, 30818, 30687, 30802, 30573, 31070, 30524, 30480, 30487, 30687, 30455, 30702, 30833, 30285, 30728, 30478, 30625, 30550, 30594, 30785, 30596, 30673, 30371, 30457, 30490, 30670, 30626, 30588, 30668, 30403, 30262, 30642, 30258, 30608, 30629, 30499, 30925, 30499, 30452, 30425, 30520, 30655, 30507, 30308, 30708, 30640] 16834.0 29044.44 28595.0 29406.0 [28878, 28894, 29010, 29236, 28974, 29335, 28983, 28993, 29115, 29359, 29230, 29047, 29053, 29019, 29043, 28957, 29204, 29107, 29085, 28778, 28973, 29193, 29044, 29149, 29406, 29230, 28883, 29184, 29007, 29016, 28726, 29007, 29253, 28995, 29231, 28712, 28925, 28955, 28923, 29103, 28937, 29189, 28883, 29253, 28595, 29258, 28757, 28847, 29006, 29106, 28878, 28745, 28984, 29098, 29041, 29074, 28916, 28909, 29175, 29133, 29219, 28826, 29080, 29193, 29215, 29037, 29037, 28766, 28936, 28968, 29083, 29087, 29221, 28945, 29159, 29014, 28902, 29124, 29050, 28998, 28926, 29192, 29097, 29033, 29187, 29351, 29310, 29100, 29157, 29023, 28783, 29028, 29009, 28982, 29169, 29004, 29158, 28950, 29006, 29120] 92740.0 74262.17 73718.0 74838.0 [74724, 74462, 74481, 74245, 74429, 74031, 74187, 74382, 74394, 74020, 74263, 74414, 74430, 74177, 74103, 74418, 73979, 74282, 74068, 74499, 74728, 74245, 74541, 73894, 74012, 73798, 74518, 74190, 74281, 74322, 74151, 74198, 73812, 74130, 74405, 74606, 74365, 74286, 74664, 74249, 74322, 74095, 74384, 74167, 74530, 74117, 74706, 74440, 74202, 74431, 74151, 74546, 74026, 74288, 74216, 73949, 74269, 74162, 74129, 73718, 74109, 74512, 74208, 74008, 74186, 74102, 74038, 74838, 74158, 74420, 74139, 74227, 74065, 74167, 74117, 74215, 74579, 74272, 74330, 74219, 74326, 74099, 74110, 74424, 74397, 73852, 74340, 74155, 74121, 74348, 74177, 74366, 74392, 74471, 74190, 74224, 74230, 74607, 74155, 74093] Lung-AdenoCA SBS4 C>T 15132.0 16324.0 66447.0 21951.96 21360.32 54813.04 3.4843428527228723e-12 2.3466363872837413e-11 5.91 1656622.0 Untranscribed 1.079 0.973 1.109 1 15132.0 21951.96 21633.0 22238.0 [21825, 21964, 21966, 21848, 22238, 22023, 21860, 22106, 22098, 22176, 21842, 21904, 22066, 22062, 22050, 21825, 22009, 21803, 22007, 21944, 22058, 21742, 22039, 21917, 22133, 21914, 22031, 21729, 21721, 21999, 21853, 21854, 22048, 22139, 21826, 21990, 22072, 22040, 21994, 21850, 21929, 22068, 21833, 22152, 21823, 22183, 21903, 21950, 21961, 22028, 21910, 21742, 21896, 21915, 22165, 22002, 21664, 21904, 21860, 21773, 21955, 21887, 21918, 22037, 21734, 22066, 21902, 21836, 21943, 22050, 22001, 22166, 21768, 21781, 21912, 21883, 21934, 21905, 21906, 21862, 21931, 22146, 21810, 22103, 21986, 21757, 21919, 21991, 21991, 21949, 21955, 22115, 21976, 22036, 22227, 21633, 22102, 22022, 21968, 21907] 16324.0 21360.32 21095.0 21660.0 [21285, 21220, 21297, 21288, 21244, 21273, 21362, 21535, 21215, 21230, 21478, 21226, 21192, 21446, 21280, 21588, 21323, 21231, 21273, 21331, 21303, 21336, 21127, 21308, 21453, 21418, 21200, 21446, 21411, 21224, 21255, 21202, 21442, 21490, 21319, 21432, 21374, 21366, 21511, 21340, 21303, 21608, 21469, 21201, 21348, 21095, 21548, 21327, 21440, 21660, 21423, 21536, 21402, 21536, 21208, 21271, 21306, 21332, 21384, 21301, 21244, 21303, 21402, 21243, 21476, 21422, 21383, 21579, 21514, 21482, 21483, 21487, 21531, 21571, 21301, 21398, 21444, 21461, 21387, 21420, 21113, 21474, 21412, 21364, 21299, 21230, 21361, 21385, 21181, 21222, 21465, 21352, 21404, 21345, 21160, 21389, 21287, 21326, 21341, 21419] 66447.0 54813.04 54415.0 55142.0 [55014, 54935, 54873, 55016, 54659, 54820, 54926, 54505, 54824, 54709, 54778, 55001, 54857, 54624, 54792, 54695, 54758, 55096, 54846, 54844, 54766, 55010, 54980, 54894, 54539, 54792, 54887, 54946, 55006, 54913, 54989, 55067, 54608, 54470, 54941, 54694, 54696, 54713, 54615, 54948, 54909, 54415, 54843, 54785, 54976, 54827, 54651, 54848, 54741, 54453, 54781, 54859, 54831, 54675, 54771, 54867, 55142, 54907, 54880, 55011, 54927, 54919, 54806, 54861, 54940, 54694, 54841, 54724, 54680, 54597, 54608, 54476, 54838, 54769, 54859, 54849, 54724, 54768, 54830, 54867, 55092, 54481, 54898, 54678, 54820, 55118, 54858, 54758, 54966, 54942, 54717, 54676, 54789, 54755, 54700, 55108, 54736, 54804, 54812, 54801] Lung-AdenoCA SBS4 T>A 54833.0 36321.0 208519.0 62053.02 66067.57 172266.11 0.0 0.0 18.089 1656622.0 Transcribed 1.51 0.939 1.607 1 1 1 1 54833.0 62053.02 61584.0 62717.0 [62005, 61967, 62156, 62349, 62246, 62183, 62062, 61930, 62182, 61613, 61830, 62000, 62070, 61965, 61881, 62020, 61946, 61653, 62301, 62010, 62122, 61851, 62036, 62080, 61806, 62296, 61956, 62132, 62253, 62050, 61956, 61922, 62306, 62717, 62279, 61992, 61987, 62041, 61762, 62086, 62386, 61969, 61950, 62322, 61901, 61792, 62002, 62074, 62221, 62003, 61977, 62084, 62002, 61877, 62065, 61787, 62057, 62012, 62022, 62260, 61584, 62219, 62348, 61972, 62276, 62143, 62383, 61802, 61970, 61868, 62100, 61965, 62049, 62252, 62184, 62170, 61748, 62052, 62386, 62132, 62128, 62425, 62301, 61986, 61968, 61990, 61884, 62092, 62301, 62170, 61760, 62054, 62008, 62470, 62038, 61594, 61844, 61738, 62321, 61865] 36321.0 66067.57 65583.0 66546.0 [66064, 66546, 66106, 65843, 65928, 66034, 66369, 66427, 66285, 65938, 65874, 65589, 65952, 65861, 65776, 66453, 66108, 65715, 66068, 66153, 66121, 66355, 65583, 65942, 65930, 65585, 66051, 65646, 65679, 66172, 66285, 66411, 65870, 66000, 65846, 65617, 65955, 66348, 66360, 66007, 66190, 66081, 65868, 65932, 66170, 65896, 66187, 66284, 66165, 65900, 66037, 65670, 66179, 65970, 66189, 66043, 66133, 65976, 66109, 66074, 66120, 66187, 65976, 66124, 66282, 65813, 66299, 66090, 66176, 66354, 66146, 66211, 65719, 66113, 66189, 65846, 65885, 66205, 65866, 66279, 66480, 66024, 66156, 65951, 66182, 66330, 66068, 65921, 66128, 66406, 65910, 66082, 66097, 66395, 65752, 66097, 66345, 66357, 66009, 66282] 208519.0 172266.11 171517.0 173000.0 [172308, 171933, 172109, 172233, 172209, 172251, 172015, 171994, 171950, 172857, 172627, 172771, 172425, 172569, 172708, 171952, 172311, 173000, 172017, 172256, 172141, 172146, 172758, 172402, 172613, 172496, 172371, 172530, 172466, 172166, 172126, 172108, 172257, 171727, 172292, 172786, 172395, 171971, 172220, 172342, 171802, 172297, 172623, 172153, 172273, 172736, 172187, 172058, 172021, 172493, 172397, 172623, 172124, 172512, 172088, 172567, 172210, 172383, 172269, 172051, 172705, 172011, 172076, 172251, 171823, 172377, 171702, 172399, 172292, 172144, 172128, 172259, 172561, 171998, 172015, 172388, 172732, 172134, 172144, 171926, 171845, 171973, 171873, 172461, 172208, 172008, 172432, 172415, 171954, 171829, 172724, 172258, 172279, 171517, 172602, 172662, 172226, 172310, 172090, 172205] Lung-AdenoCA SBS4 T>C 2674.0 1595.0 8951.0 2842.83 2796.13 7605.64 5.974303010511953e-34 6.280520774120519e-33 0.798 1656622.0 Transcribed 1.676 1.017 1.649 1 1 1 1 2674.0 2842.83 2716.0 2956.0 [2809, 2864, 2812, 2912, 2938, 2887, 2896, 2780, 2826, 2934, 2761, 2770, 2840, 2894, 2791, 2842, 2840, 2829, 2819, 2845, 2896, 2871, 2951, 2874, 2816, 2827, 2825, 2813, 2814, 2873, 2799, 2830, 2816, 2750, 2878, 2834, 2784, 2802, 2861, 2812, 2764, 2892, 2851, 2825, 2797, 2791, 2866, 2790, 2840, 2785, 2806, 2870, 2812, 2824, 2836, 2831, 2824, 2865, 2776, 2841, 2857, 2922, 2896, 2857, 2823, 2813, 2716, 2854, 2954, 2871, 2956, 2886, 2860, 2817, 2888, 2892, 2775, 2897, 2922, 2812, 2789, 2864, 2928, 2946, 2909, 2842, 2916, 2872, 2819, 2898, 2900, 2846, 2811, 2812, 2741, 2825, 2800, 2770, 2746, 2880] 1595.0 2796.13 2704.0 2910.0 [2743, 2804, 2825, 2785, 2771, 2871, 2743, 2823, 2711, 2744, 2805, 2809, 2806, 2751, 2790, 2818, 2778, 2796, 2778, 2813, 2769, 2769, 2806, 2812, 2765, 2802, 2746, 2768, 2838, 2804, 2792, 2831, 2764, 2868, 2768, 2807, 2793, 2855, 2773, 2795, 2772, 2753, 2910, 2799, 2843, 2737, 2764, 2886, 2802, 2726, 2798, 2834, 2830, 2843, 2842, 2799, 2816, 2832, 2794, 2800, 2855, 2775, 2776, 2809, 2746, 2812, 2838, 2723, 2715, 2788, 2738, 2766, 2838, 2845, 2853, 2875, 2806, 2704, 2771, 2840, 2800, 2821, 2843, 2733, 2728, 2768, 2757, 2795, 2775, 2842, 2769, 2803, 2765, 2803, 2851, 2808, 2816, 2725, 2882, 2787] 8951.0 7605.64 7476.0 7732.0 [7683, 7572, 7610, 7544, 7542, 7486, 7600, 7643, 7705, 7562, 7671, 7663, 7593, 7593, 7669, 7591, 7623, 7618, 7653, 7583, 7588, 7604, 7497, 7559, 7649, 7618, 7671, 7663, 7583, 7575, 7648, 7590, 7668, 7624, 7606, 7602, 7658, 7589, 7604, 7629, 7712, 7601, 7494, 7624, 7609, 7704, 7610, 7578, 7600, 7732, 7632, 7546, 7593, 7583, 7566, 7616, 7608, 7563, 7674, 7590, 7530, 7544, 7569, 7569, 7686, 7620, 7686, 7675, 7578, 7581, 7555, 7607, 7561, 7584, 7511, 7476, 7658, 7640, 7552, 7585, 7655, 7562, 7476, 7564, 7598, 7643, 7583, 7576, 7658, 7520, 7580, 7590, 7679, 7626, 7655, 7618, 7628, 7731, 7614, 7577] Lung-AdenoCA SBS4 T>G 2033.0 1568.0 7312.0 2268.78 2476.73 6179.31 4.81677405752602e-15 3.57415388208152e-14 0.659 1656622.0 Transcribed 1.297 0.916 1.415 1 1 1 2033.0 2268.78 2171.0 2361.0 [2248, 2239, 2179, 2205, 2202, 2266, 2336, 2275, 2299, 2284, 2232, 2305, 2262, 2316, 2323, 2353, 2234, 2222, 2262, 2235, 2258, 2238, 2340, 2344, 2295, 2301, 2220, 2266, 2323, 2250, 2327, 2282, 2217, 2217, 2271, 2293, 2250, 2355, 2218, 2214, 2319, 2188, 2282, 2312, 2238, 2255, 2314, 2241, 2247, 2314, 2222, 2191, 2303, 2244, 2219, 2323, 2319, 2281, 2284, 2285, 2271, 2171, 2306, 2254, 2207, 2237, 2361, 2351, 2252, 2303, 2237, 2318, 2262, 2299, 2252, 2254, 2317, 2290, 2323, 2310, 2194, 2242, 2261, 2280, 2264, 2238, 2250, 2251, 2303, 2246, 2305, 2269, 2212, 2294, 2316, 2243, 2227, 2223, 2211, 2337] 1568.0 2476.73 2378.0 2591.0 [2482, 2501, 2425, 2550, 2454, 2449, 2446, 2454, 2433, 2429, 2510, 2464, 2480, 2378, 2509, 2426, 2459, 2483, 2576, 2407, 2511, 2494, 2460, 2488, 2475, 2493, 2379, 2493, 2443, 2555, 2435, 2414, 2436, 2508, 2468, 2491, 2538, 2448, 2542, 2542, 2394, 2495, 2478, 2478, 2519, 2454, 2394, 2504, 2434, 2519, 2451, 2456, 2477, 2440, 2502, 2410, 2475, 2521, 2449, 2517, 2456, 2495, 2445, 2537, 2433, 2478, 2498, 2455, 2474, 2448, 2449, 2425, 2473, 2407, 2498, 2433, 2472, 2489, 2509, 2539, 2475, 2570, 2481, 2541, 2448, 2560, 2484, 2591, 2469, 2478, 2553, 2497, 2412, 2430, 2466, 2501, 2555, 2570, 2473, 2411] 7312.0 6179.31 6060.0 6321.0 [6196, 6188, 6306, 6161, 6281, 6205, 6152, 6191, 6191, 6231, 6179, 6159, 6176, 6224, 6095, 6145, 6219, 6222, 6089, 6280, 6160, 6191, 6137, 6088, 6157, 6133, 6321, 6173, 6163, 6125, 6173, 6223, 6264, 6210, 6179, 6137, 6140, 6130, 6165, 6166, 6208, 6238, 6162, 6137, 6167, 6210, 6219, 6171, 6232, 6097, 6249, 6282, 6154, 6230, 6195, 6186, 6149, 6136, 6187, 6126, 6202, 6255, 6175, 6129, 6282, 6212, 6076, 6106, 6195, 6186, 6246, 6171, 6187, 6226, 6172, 6242, 6132, 6144, 6097, 6072, 6244, 6117, 6174, 6102, 6214, 6132, 6198, 6080, 6163, 6216, 6060, 6165, 6302, 6194, 6139, 6187, 6136, 6126, 6236, 6179] Lung-SCC SBS4 C>A 124900.0 77710.0 496221.0 156654.96 149758.03 394544.7 0.0 0.0 72.475 964231.0 Transcribed 1.607 1.046 1.536 1 1 1 1 124900.0 156654.96 155937.0 157555.0 [156678, 157222, 156239, 156516, 156759, 156761, 156480, 156520, 156584, 156248, 156510, 156300, 155977, 156182, 156859, 156444, 157247, 156900, 156714, 157038, 156449, 156817, 157137, 156714, 156844, 155986, 156394, 156723, 156806, 156834, 156574, 156950, 156983, 156584, 156793, 156203, 156513, 156569, 156771, 156831, 156387, 157056, 156736, 156291, 156385, 157555, 157072, 156654, 156703, 157006, 156519, 156919, 156760, 157326, 156562, 156436, 156114, 156263, 156332, 157445, 156883, 156501, 156160, 157131, 156078, 156516, 155978, 156622, 156340, 156116, 156656, 156741, 155937, 156687, 156190, 156655, 157003, 156855, 156678, 156662, 156999, 156292, 156877, 156747, 156956, 157053, 156436, 156849, 156970, 156689, 156411, 157252, 156689, 156492, 156900, 156958, 156573, 156624, 156814, 156352] 77710.0 149758.03 148917.0 150668.0 [149731, 148998, 150029, 149968, 149737, 149862, 149556, 150489, 149833, 149660, 149228, 150011, 149714, 150217, 149134, 149915, 149885, 149289, 150084, 149685, 149855, 150030, 149835, 149670, 149633, 149819, 149596, 149208, 149752, 150106, 150241, 149496, 149216, 150315, 148917, 150388, 149245, 150078, 149331, 150668, 149648, 149924, 149818, 149892, 149757, 149343, 149659, 149976, 149242, 150299, 150335, 149328, 150437, 149436, 149703, 149920, 150579, 149614, 149979, 149842, 149428, 149719, 150016, 150005, 150541, 149226, 150105, 149833, 149062, 149755, 149909, 149175, 149877, 149567, 149363, 149824, 149747, 150141, 149993, 149970, 150158, 149421, 149685, 149457, 149366, 148976, 150248, 149538, 149353, 149937, 149622, 149524, 149208, 149671, 150239, 149830, 149504, 149780, 149849, 150026] 496221.0 394544.7 393538.0 395561.0 [394594, 394599, 394657, 394460, 394462, 394309, 394895, 393981, 394559, 395076, 395243, 394643, 395250, 394638, 394910, 394564, 393857, 394734, 394193, 394287, 394613, 394118, 393927, 394623, 394488, 395105, 394968, 394995, 394424, 393987, 394148, 394605, 394830, 394030, 395161, 394358, 395225, 394279, 394772, 393538, 394963, 393936, 394484, 394765, 394818, 393925, 394183, 394364, 394993, 393601, 394102, 394732, 393791, 394224, 394705, 394586, 394262, 395022, 394528, 393718, 394572, 394860, 394707, 393881, 394320, 395156, 394808, 394540, 395561, 395038, 394326, 395057, 395181, 394760, 395375, 394534, 394142, 393990, 394366, 394351, 393834, 395275, 394401, 394814, 394614, 394951, 394342, 394547, 394642, 394316, 394938, 394168, 395111, 394795, 393867, 394203, 394896, 394548, 394346, 394530] Lung-SCC SBS4 C>G 8051.0 6022.0 30735.0 10406.62 9938.22 24615.86 1.4884620947486982e-28 1.43524830484258e-27 4.647 964231.0 Transcribed 1.337 1.047 1.277 1 1 8051.0 10406.62 10165.0 10639.0 [10433, 10392, 10435, 10411, 10580, 10568, 10430, 10437, 10425, 10303, 10292, 10385, 10427, 10315, 10350, 10245, 10510, 10476, 10389, 10357, 10498, 10270, 10456, 10387, 10430, 10587, 10296, 10472, 10516, 10542, 10216, 10243, 10446, 10389, 10392, 10362, 10417, 10350, 10253, 10428, 10404, 10376, 10469, 10425, 10454, 10501, 10438, 10569, 10450, 10276, 10452, 10295, 10481, 10470, 10469, 10374, 10404, 10278, 10165, 10639, 10459, 10230, 10384, 10250, 10309, 10473, 10413, 10445, 10460, 10619, 10461, 10340, 10372, 10246, 10317, 10433, 10544, 10377, 10345, 10357, 10374, 10410, 10306, 10421, 10360, 10438, 10430, 10426, 10506, 10529, 10499, 10179, 10433, 10407, 10268, 10380, 10538, 10331, 10590, 10504] 6022.0 9938.22 9675.0 10163.0 [9958, 9978, 10026, 9922, 9894, 9812, 9884, 9834, 9965, 10087, 9886, 9933, 10080, 10092, 10034, 10026, 9813, 9900, 10028, 9928, 10013, 9993, 9961, 9922, 9835, 9799, 10043, 9914, 9862, 10002, 9816, 9981, 10026, 9822, 9865, 9900, 9882, 9847, 9963, 9828, 9930, 9936, 9889, 9831, 10008, 9949, 9990, 9997, 10035, 9956, 9961, 10044, 9870, 10054, 9992, 9933, 9974, 9893, 9864, 9830, 10036, 10020, 9897, 10037, 9865, 9900, 10072, 9826, 9889, 9879, 9881, 9933, 10018, 10010, 9881, 9811, 9896, 10031, 9766, 9931, 9861, 10163, 9973, 9960, 9865, 9926, 9885, 9992, 10032, 9878, 9995, 9941, 9989, 9956, 10039, 9983, 9675, 9989, 9893, 9958] 30735.0 24615.86 24389.0 24903.0 [24580, 24597, 24507, 24632, 24501, 24572, 24658, 24688, 24543, 24567, 24783, 24636, 24479, 24548, 24574, 24681, 24663, 24584, 24554, 24670, 24423, 24689, 24529, 24647, 24710, 24589, 24642, 24580, 24583, 24411, 24903, 24746, 24493, 24763, 24690, 24704, 24642, 24792, 24740, 24722, 24618, 24664, 24598, 24707, 24471, 24498, 24552, 24417, 24476, 24755, 24564, 24607, 24599, 24440, 24505, 24641, 24620, 24795, 24899, 24505, 24496, 24665, 24692, 24681, 24785, 24588, 24500, 24673, 24647, 24437, 24593, 24691, 24579, 24681, 24769, 24699, 24510, 24541, 24829, 24673, 24718, 24389, 24656, 24574, 24700, 24592, 24612, 24543, 24439, 24540, 24505, 24860, 24544, 24602, 24673, 24600, 24734, 24633, 24488, 24509] Lung-SCC SBS4 C>T 2399.0 2670.0 10195.0 3464.46 3351.94 8484.3 0.00016603390795889186 0.0007416399975665758 1.583 964231.0 Untranscribed 1.113 0.968 1.15 1 2399.0 3464.46 3345.0 3591.0 [3523, 3402, 3433, 3433, 3505, 3493, 3469, 3486, 3536, 3477, 3407, 3486, 3591, 3420, 3551, 3518, 3473, 3408, 3458, 3423, 3454, 3466, 3471, 3551, 3482, 3391, 3430, 3492, 3523, 3482, 3444, 3490, 3403, 3455, 3461, 3459, 3416, 3555, 3395, 3465, 3436, 3458, 3349, 3462, 3454, 3483, 3386, 3544, 3487, 3473, 3445, 3497, 3541, 3439, 3470, 3425, 3530, 3391, 3524, 3511, 3454, 3516, 3496, 3446, 3452, 3450, 3455, 3497, 3567, 3428, 3436, 3522, 3447, 3473, 3532, 3405, 3358, 3345, 3529, 3399, 3389, 3485, 3513, 3376, 3459, 3495, 3411, 3412, 3500, 3526, 3433, 3432, 3443, 3516, 3481, 3543, 3463, 3383, 3486, 3411] 2670.0 3351.94 3245.0 3473.0 [3378, 3387, 3409, 3382, 3287, 3380, 3391, 3357, 3409, 3333, 3417, 3383, 3277, 3251, 3258, 3312, 3391, 3450, 3370, 3321, 3366, 3340, 3403, 3331, 3373, 3378, 3447, 3329, 3269, 3245, 3313, 3390, 3371, 3314, 3431, 3361, 3340, 3302, 3347, 3414, 3401, 3357, 3344, 3261, 3377, 3384, 3399, 3325, 3343, 3380, 3354, 3384, 3367, 3376, 3317, 3377, 3292, 3338, 3309, 3378, 3370, 3320, 3306, 3355, 3335, 3258, 3265, 3367, 3369, 3348, 3426, 3268, 3390, 3331, 3264, 3404, 3425, 3367, 3339, 3458, 3299, 3379, 3277, 3354, 3289, 3336, 3426, 3272, 3307, 3353, 3337, 3325, 3333, 3473, 3419, 3322, 3372, 3395, 3286, 3405] 10195.0 8484.3 8337.0 8634.0 [8401, 8502, 8454, 8474, 8520, 8420, 8458, 8477, 8371, 8486, 8470, 8429, 8436, 8634, 8487, 8477, 8452, 8444, 8455, 8550, 8467, 8486, 8413, 8415, 8445, 8541, 8422, 8476, 8505, 8587, 8532, 8413, 8513, 8526, 8422, 8494, 8533, 8447, 8566, 8410, 8474, 8486, 8608, 8564, 8473, 8432, 8533, 8443, 8472, 8442, 8508, 8438, 8395, 8479, 8510, 8504, 8473, 8585, 8453, 8407, 8500, 8479, 8491, 8487, 8520, 8574, 8570, 8431, 8363, 8534, 8437, 8511, 8471, 8504, 8505, 8476, 8525, 8566, 8440, 8442, 8623, 8431, 8501, 8564, 8551, 8469, 8453, 8613, 8480, 8429, 8523, 8552, 8533, 8337, 8407, 8427, 8499, 8522, 8518, 8483] Lung-SCC SBS4 T>A 35844.0 25385.0 141969.0 42015.37 44807.44 116890.63 0.0 0.0 21.074 964231.0 Transcribed 1.412 0.938 1.506 1 1 1 1 35844.0 42015.37 41615.0 42390.0 [41829, 42311, 42278, 42305, 42050, 42141, 42245, 41904, 42019, 41855, 41938, 41775, 42029, 42045, 41961, 42018, 41856, 42128, 41861, 42253, 41797, 41952, 41880, 42056, 41615, 42005, 42080, 41932, 41683, 41838, 41928, 41987, 42154, 41914, 41859, 42117, 42160, 41986, 41865, 41999, 42206, 42099, 42192, 42355, 42298, 41794, 41896, 42288, 41839, 41848, 41901, 41956, 42120, 41984, 42309, 42220, 41839, 42257, 42058, 41964, 42153, 41820, 41937, 42041, 41954, 42008, 41663, 42141, 42047, 41981, 42176, 42060, 42158, 41949, 42050, 41820, 41994, 42390, 41690, 41965, 42115, 41912, 42034, 42017, 41800, 41956, 41991, 41809, 42026, 42108, 42086, 42118, 41929, 42296, 41961, 41739, 42025, 42196, 42093, 42298] 25385.0 44807.44 44360.0 45148.0 [44594, 44873, 44477, 44522, 44878, 44653, 44739, 44738, 44725, 44877, 44932, 44779, 44589, 44778, 44761, 44978, 44744, 44944, 44752, 44610, 45023, 44686, 44738, 44821, 45030, 44778, 44825, 44655, 45077, 44775, 44999, 44811, 44563, 44684, 44894, 44457, 44928, 44555, 45148, 44936, 44629, 44819, 44659, 44684, 44697, 45000, 44913, 44769, 44718, 45041, 44963, 44867, 44709, 44592, 44802, 44744, 44792, 44893, 44887, 44360, 44982, 44980, 44991, 44972, 44855, 44853, 44772, 44724, 44791, 44993, 44971, 44578, 44680, 44833, 44973, 44714, 44761, 44864, 44910, 44793, 44676, 44723, 44676, 44981, 44902, 44867, 45081, 45032, 44841, 44899, 45062, 45016, 44788, 45011, 45082, 44658, 44552, 44520, 44586, 44937] 141969.0 116890.63 116408.0 117368.0 [117272, 116556, 116977, 116900, 116813, 116916, 116786, 117086, 116969, 116975, 116811, 117132, 117016, 116869, 116994, 116690, 117104, 116656, 117101, 116844, 116904, 117068, 117096, 116862, 117070, 116910, 116792, 117117, 116927, 117108, 116796, 116936, 116980, 117098, 116940, 117132, 116647, 117212, 116646, 116749, 116875, 116812, 116851, 116674, 116719, 116926, 116892, 116662, 117180, 116827, 116811, 116899, 116877, 117119, 116556, 116769, 117107, 116546, 116801, 117368, 116632, 116907, 116809, 116716, 116878, 116910, 117260, 116837, 116908, 116772, 116570, 117043, 116924, 116888, 116677, 117173, 116971, 116421, 117064, 117002, 116933, 117112, 117023, 116714, 116979, 116913, 116664, 116889, 116813, 116694, 116594, 116574, 117038, 116408, 116670, 117301, 117093, 117026, 117044, 116491] Lung-SCC SBS4 T>C 111.0 58.0 365.0 118.53 118.85 299.37 0.0022472253935905857 0.008907714546814174 0.055 964231.0 Transcribed 1.914 0.997 1.919 1 1 1 1 1 111.0 118.53 100.0 141.0 [138, 114, 111, 118, 123, 118, 109, 133, 118, 118, 129, 118, 123, 108, 116, 122, 117, 110, 107, 108, 119, 111, 115, 122, 124, 121, 122, 119, 103, 118, 118, 135, 121, 119, 108, 138, 101, 109, 114, 108, 130, 115, 123, 131, 112, 136, 119, 120, 117, 109, 116, 121, 128, 128, 133, 105, 110, 102, 112, 122, 141, 118, 134, 109, 108, 110, 120, 121, 131, 114, 122, 113, 107, 118, 120, 115, 134, 115, 116, 132, 105, 117, 113, 125, 124, 120, 141, 114, 106, 119, 121, 100, 116, 127, 110, 101, 112, 129, 128, 135] 58.0 118.85 97.0 141.0 [108, 122, 121, 121, 110, 114, 114, 126, 106, 126, 110, 121, 139, 110, 128, 121, 119, 126, 134, 127, 109, 131, 127, 115, 121, 115, 118, 118, 131, 108, 125, 114, 105, 117, 116, 112, 122, 108, 141, 135, 110, 124, 120, 107, 114, 118, 127, 131, 113, 106, 135, 121, 120, 125, 128, 121, 117, 97, 108, 119, 112, 123, 106, 132, 115, 100, 101, 109, 104, 135, 107, 122, 117, 119, 127, 126, 102, 113, 119, 132, 132, 111, 127, 114, 125, 117, 105, 117, 119, 123, 119, 129, 136, 115, 122, 126, 124, 137, 111, 103] 365.0 299.37 272.0 336.0 [293, 302, 303, 299, 305, 305, 313, 275, 311, 295, 298, 299, 274, 318, 293, 294, 300, 300, 298, 305, 313, 296, 295, 300, 290, 301, 298, 300, 303, 312, 294, 287, 311, 302, 316, 286, 313, 319, 284, 293, 297, 301, 293, 300, 309, 282, 293, 285, 307, 321, 285, 294, 290, 284, 275, 310, 309, 336, 318, 295, 282, 295, 294, 296, 311, 327, 314, 306, 302, 287, 307, 302, 314, 301, 289, 296, 303, 308, 303, 272, 298, 307, 295, 296, 287, 300, 291, 306, 313, 294, 295, 307, 284, 293, 305, 308, 298, 275, 300, 299] Lung-SCC SBS4 T>G 296.0 231.0 1069.0 340.58 365.98 893.1 0.006746273119867002 0.025103599778602895 0.166 964231.0 Transcribed 1.281 0.931 1.377 1 1 1 296.0 340.58 304.0 388.0 [355, 368, 337, 328, 353, 339, 305, 350, 335, 324, 327, 361, 329, 333, 350, 321, 318, 333, 347, 348, 329, 323, 335, 377, 334, 356, 337, 324, 335, 343, 381, 335, 324, 336, 325, 363, 342, 348, 315, 351, 388, 340, 349, 338, 355, 345, 304, 324, 351, 311, 362, 320, 348, 321, 352, 361, 351, 337, 345, 324, 378, 320, 306, 334, 361, 353, 344, 340, 369, 328, 340, 360, 335, 352, 351, 352, 338, 335, 343, 317, 340, 329, 320, 340, 332, 331, 320, 349, 348, 353, 353, 353, 343, 318, 348, 376, 344, 338, 330, 337] 231.0 365.98 327.0 408.0 [353, 373, 341, 383, 329, 372, 386, 369, 378, 392, 376, 382, 376, 377, 350, 371, 351, 390, 362, 344, 348, 382, 378, 357, 367, 343, 366, 383, 372, 369, 364, 380, 353, 374, 384, 327, 374, 353, 367, 380, 351, 358, 362, 408, 363, 384, 382, 360, 342, 356, 357, 365, 377, 373, 372, 356, 392, 342, 362, 372, 345, 347, 363, 356, 369, 362, 354, 357, 346, 371, 381, 340, 369, 361, 354, 366, 379, 407, 360, 380, 356, 353, 367, 383, 367, 370, 371, 369, 356, 334, 349, 381, 383, 406, 362, 353, 364, 386, 370, 341] 1069.0 893.1 853.0 938.0 [889, 862, 918, 892, 913, 891, 910, 878, 888, 883, 899, 857, 894, 891, 895, 909, 926, 873, 891, 908, 922, 897, 888, 862, 899, 902, 893, 895, 890, 887, 853, 886, 923, 888, 888, 912, 880, 904, 912, 867, 858, 904, 889, 854, 884, 878, 910, 917, 908, 930, 881, 913, 881, 902, 875, 887, 858, 917, 892, 908, 877, 938, 931, 907, 870, 879, 902, 906, 885, 899, 879, 904, 899, 886, 892, 882, 882, 861, 894, 905, 900, 918, 910, 879, 899, 899, 908, 882, 896, 915, 898, 868, 873, 876, 895, 871, 890, 871, 899, 924] Summary across all cancer types signature mutation_type strand fold_change_1.1 len(fold_change_1.1_cancer_types) fold_change_1.2 len(fold_change_1.2_cancer_types) fold_change_1.3 len(fold_change_1.3_cancer_types) fold_change_1.5 len(fold_change_1.5_cancer_types) fold_change_1.75 len(fold_change_1.75_cancer_types) fold_change_2+ len(fold_change_2+_cancer_types) all_cancer_types_list len(all_cancer_types_list) avg_fold_change SBS4 C>A Transcribed ['ESCC', 'Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 5 ['ESCC', 'Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 5 ['Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 4 ['Lung-AdenoCA', 'Lung-SCC'] 2 [] 0 [] 0 ['ESCC', 'Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 5 1.3599999999999999 SBS4 C>G Transcribed ['Head-SCC', 'Lung-AdenoCA'] 2 ['Lung-AdenoCA'] 1 ['Lung-AdenoCA'] 1 [] 0 [] 0 [] 0 ['ESCC', 'Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 5 1.2000000000000002 SBS4 C>T Untranscribed ['Lung-AdenoCA'] 1 [] 0 [] 0 [] 0 [] 0 [] 0 ['ESCC', 'Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 5 1.1 SBS4 T>A Transcribed ['Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 4 ['Head-SCC', 'Lung-AdenoCA', 'Lung-SCC'] 3 ['Lung-AdenoCA', 'Lung-SCC'] 2 ['Lung-AdenoCA', 'Lung-SCC'] 2 [] 0 [] 0 ['ESCC', 'Head-SCC', 'Liver-HCC', 'Lung-AdenoCA', 'Lung-SCC'] 5 1.325