# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	dna_element	encode_element_list	fold_change_list	avg_fold_change	p_value_list	combined_p_value	q_value
SBS43	Skin-Melanoma	H3K27ac-human	['ENCFF731TOU_foreskin-fibroblast_Normal_H3K27ac-human', 'ENCFF704UVU_foreskin-melanocyte_Normal_H3K27ac-human']	[1.119, 1.265]	1.192	[5.539927923212315e-18, 6.591178533288114e-45]	5.202065557522918e-60	3.737888678692029e-59
SBS43	Skin-Melanoma	H3K27me3-human	['ENCFF260QSX_foreskin-fibroblast_Normal_H3K27me3-human', 'ENCFF640WPP_foreskin-melanocyte_Normal_H3K27me3-human']	[1.132, 1.267]	1.2	[3.032801783308961e-79, 5.847613516682841e-132]	8.583038699520167e-208	1.0941235710983018e-206
SBS43	Skin-Melanoma	H3K36me3-human	['ENCFF778WQB_foreskin-fibroblast_Normal_H3K36me3-human', 'ENCFF377DZS_foreskin-melanocyte_Normal_H3K36me3-human']	[1.044, 1.024]	1.034	[1.8420206887816645e-14, 9.388727790282918e-05]	7.246065467900776e-17	2.911324942443484e-16
SBS43	Skin-Melanoma	H3K4me1-human	['ENCFF772YVC_foreskin-fibroblast_Normal_H3K4me1-human', 'ENCFF234OVO_foreskin-melanocyte_Normal_H3K4me1-human']	[1.051, 1.09]	1.071	[5.485141607138921e-23, 2.537996468594442e-37]	1.9005552791175607e-57	1.3258964738134692e-56
SBS43	Skin-Melanoma	H3K4me3-human	['ENCFF644IVA_foreskin-fibroblast_Normal_H3K4me3-human', 'ENCFF499KTB_foreskin-melanocyte_Normal_H3K4me3-human', 'ENCFF496WOM_lower-leg-skin_Normal_H3K4me3-human']	[1.008, 1.075, 1.024]	1.036	[0.5976162896301196, 1.5281799266384138e-07, 0.13199915485714261]	2.235835966142454e-06	6.127787572920425e-06
SBS43	Skin-Melanoma	H3K9ac-human	['ENCFF973JPP_foreskin-melanocyte_Normal_H3K9ac-human']	[1.305]	1.305	[4.388209739816297e-39]	4.388209739816304e-39	2.528162278029303e-38
SBS43	Skin-Melanoma	H3K9me3-human	['ENCFF342TCS_foreskin-fibroblast_Normal_H3K9me3-human', 'ENCFF849GBJ_foreskin-melanocyte_Normal_H3K9me3-human']	[1.07, 1.087]	1.078	[2.9633268605165416e-43, 1.4231902293536483e-37]	7.750173770479327e-78	6.273716615470291e-77