# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
# For real mutations on genic (transcribed:T, untranscribed:U and bitranscribed:B) and intergenic (nontranscribed:N) regions averaged across cancer types.
MutationType	Across_All_Cancer_Types
T:A[C>A]A	448.0
U:A[C>A]A	290.0
B:A[C>A]A	8.0
N:A[C>A]A	1085.0
T:A[C>A]C	86.0
U:A[C>A]C	65.0
B:A[C>A]C	0.0
N:A[C>A]C	244.0
T:A[C>A]G	2.0
U:A[C>A]G	3.0
B:A[C>A]G	0.0
N:A[C>A]G	24.0
T:A[C>A]T	31.0
U:A[C>A]T	24.0
B:A[C>A]T	0.0
N:A[C>A]T	94.0
T:A[C>G]A	2.0
U:A[C>G]A	2.0
B:A[C>G]A	0.0
N:A[C>G]A	20.0
T:A[C>G]C	0.0
U:A[C>G]C	0.0
B:A[C>G]C	0.0
N:A[C>G]C	1.0
T:A[C>G]G	22.0
U:A[C>G]G	27.0
B:A[C>G]G	0.0
N:A[C>G]G	99.0
T:A[C>G]T	3.0
U:A[C>G]T	1.0
B:A[C>G]T	0.0
N:A[C>G]T	7.0
T:A[C>T]A	0.0
U:A[C>T]A	0.0
B:A[C>T]A	0.0
N:A[C>T]A	1.0
T:A[C>T]C	0.0
U:A[C>T]C	0.0
B:A[C>T]C	0.0
N:A[C>T]C	3.0
T:A[C>T]G	14.0
U:A[C>T]G	13.0
B:A[C>T]G	0.0
N:A[C>T]G	58.0
T:A[C>T]T	38.0
U:A[C>T]T	34.0
B:A[C>T]T	0.0
N:A[C>T]T	104.0
T:A[T>A]A	445.0
U:A[T>A]A	247.0
B:A[T>A]A	4.0
N:A[T>A]A	1033.0
T:A[T>A]C	70.0
U:A[T>A]C	57.0
B:A[T>A]C	0.0
N:A[T>A]C	181.0
T:A[T>A]G	57.0
U:A[T>A]G	45.0
B:A[T>A]G	0.0
N:A[T>A]G	130.0
T:A[T>A]T	105.0
U:A[T>A]T	82.0
B:A[T>A]T	0.0
N:A[T>A]T	344.0
T:A[T>C]A	0.0
U:A[T>C]A	0.0
B:A[T>C]A	0.0
N:A[T>C]A	0.0
T:A[T>C]C	992.0
U:A[T>C]C	785.0
B:A[T>C]C	16.0
N:A[T>C]C	2166.0
T:A[T>C]G	2.0
U:A[T>C]G	2.0
B:A[T>C]G	0.0
N:A[T>C]G	14.0
T:A[T>C]T	34.0
U:A[T>C]T	20.0
B:A[T>C]T	0.0
N:A[T>C]T	129.0
T:A[T>G]A	24.0
U:A[T>G]A	25.0
B:A[T>G]A	0.0
N:A[T>G]A	113.0
T:A[T>G]C	7.0
U:A[T>G]C	5.0
B:A[T>G]C	0.0
N:A[T>G]C	64.0
T:A[T>G]G	143.0
U:A[T>G]G	170.0
B:A[T>G]G	1.0
N:A[T>G]G	575.0
T:A[T>G]T	14.0
U:A[T>G]T	24.0
B:A[T>G]T	0.0
N:A[T>G]T	105.0
T:C[C>A]A	117.0
U:C[C>A]A	80.0
B:C[C>A]A	2.0
N:C[C>A]A	361.0
T:C[C>A]C	0.0
U:C[C>A]C	1.0
B:C[C>A]C	0.0
N:C[C>A]C	3.0
T:C[C>A]G	0.0
U:C[C>A]G	0.0
B:C[C>A]G	0.0
N:C[C>A]G	0.0
T:C[C>A]T	0.0
U:C[C>A]T	0.0
B:C[C>A]T	0.0
N:C[C>A]T	0.0
T:C[C>G]A	0.0
U:C[C>G]A	0.0
B:C[C>G]A	0.0
N:C[C>G]A	0.0
T:C[C>G]C	0.0
U:C[C>G]C	0.0
B:C[C>G]C	0.0
N:C[C>G]C	1.0
T:C[C>G]G	80.0
U:C[C>G]G	89.0
B:C[C>G]G	5.0
N:C[C>G]G	118.0
T:C[C>G]T	5.0
U:C[C>G]T	4.0
B:C[C>G]T	0.0
N:C[C>G]T	12.0
T:C[C>T]A	0.0
U:C[C>T]A	0.0
B:C[C>T]A	0.0
N:C[C>T]A	0.0
T:C[C>T]C	0.0
U:C[C>T]C	0.0
B:C[C>T]C	0.0
N:C[C>T]C	0.0
T:C[C>T]G	0.0
U:C[C>T]G	0.0
B:C[C>T]G	0.0
N:C[C>T]G	3.0
T:C[C>T]T	29.0
U:C[C>T]T	35.0
B:C[C>T]T	0.0
N:C[C>T]T	101.0
T:C[T>A]A	59.0
U:C[T>A]A	30.0
B:C[T>A]A	0.0
N:C[T>A]A	147.0
T:C[T>A]C	0.0
U:C[T>A]C	0.0
B:C[T>A]C	0.0
N:C[T>A]C	0.0
T:C[T>A]G	1.0
U:C[T>A]G	0.0
B:C[T>A]G	0.0
N:C[T>A]G	8.0
T:C[T>A]T	2.0
U:C[T>A]T	1.0
B:C[T>A]T	0.0
N:C[T>A]T	8.0
T:C[T>C]A	55.0
U:C[T>C]A	43.0
B:C[T>C]A	2.0
N:C[T>C]A	153.0
T:C[T>C]C	2648.0
U:C[T>C]C	2366.0
B:C[T>C]C	72.0
N:C[T>C]C	5298.0
T:C[T>C]G	312.0
U:C[T>C]G	312.0
B:C[T>C]G	12.0
N:C[T>C]G	586.0
T:C[T>C]T	180.0
U:C[T>C]T	170.0
B:C[T>C]T	1.0
N:C[T>C]T	439.0
T:C[T>G]A	7.0
U:C[T>G]A	6.0
B:C[T>G]A	0.0
N:C[T>G]A	44.0
T:C[T>G]C	17.0
U:C[T>G]C	15.0
B:C[T>G]C	0.0
N:C[T>G]C	72.0
T:C[T>G]G	283.0
U:C[T>G]G	287.0
B:C[T>G]G	7.0
N:C[T>G]G	675.0
T:C[T>G]T	0.0
U:C[T>G]T	0.0
B:C[T>G]T	0.0
N:C[T>G]T	0.0
T:G[C>A]A	81.0
U:G[C>A]A	57.0
B:G[C>A]A	0.0
N:G[C>A]A	269.0
T:G[C>A]C	3.0
U:G[C>A]C	0.0
B:G[C>A]C	0.0
N:G[C>A]C	25.0
T:G[C>A]G	1.0
U:G[C>A]G	2.0
B:G[C>A]G	0.0
N:G[C>A]G	4.0
T:G[C>A]T	3.0
U:G[C>A]T	3.0
B:G[C>A]T	0.0
N:G[C>A]T	27.0
T:G[C>G]A	130.0
U:G[C>G]A	124.0
B:G[C>G]A	1.0
N:G[C>G]A	328.0
T:G[C>G]C	87.0
U:G[C>G]C	103.0
B:G[C>G]C	1.0
N:G[C>G]C	303.0
T:G[C>G]G	317.0
U:G[C>G]G	362.0
B:G[C>G]G	3.0
N:G[C>G]G	622.0
T:G[C>G]T	77.0
U:G[C>G]T	102.0
B:G[C>G]T	2.0
N:G[C>G]T	267.0
T:G[C>T]A	2.0
U:G[C>T]A	4.0
B:G[C>T]A	0.0
N:G[C>T]A	26.0
T:G[C>T]C	0.0
U:G[C>T]C	0.0
B:G[C>T]C	0.0
N:G[C>T]C	0.0
T:G[C>T]G	0.0
U:G[C>T]G	0.0
B:G[C>T]G	0.0
N:G[C>T]G	0.0
T:G[C>T]T	36.0
U:G[C>T]T	60.0
B:G[C>T]T	1.0
N:G[C>T]T	135.0
T:G[T>A]A	44.0
U:G[T>A]A	40.0
B:G[T>A]A	0.0
N:G[T>A]A	147.0
T:G[T>A]C	2.0
U:G[T>A]C	4.0
B:G[T>A]C	0.0
N:G[T>A]C	26.0
T:G[T>A]G	19.0
U:G[T>A]G	22.0
B:G[T>A]G	0.0
N:G[T>A]G	94.0
T:G[T>A]T	1.0
U:G[T>A]T	8.0
B:G[T>A]T	0.0
N:G[T>A]T	32.0
T:G[T>C]A	0.0
U:G[T>C]A	0.0
B:G[T>C]A	0.0
N:G[T>C]A	0.0
T:G[T>C]C	676.0
U:G[T>C]C	543.0
B:G[T>C]C	13.0
N:G[T>C]C	1333.0
T:G[T>C]G	13.0
U:G[T>C]G	7.0
B:G[T>C]G	0.0
N:G[T>C]G	57.0
T:G[T>C]T	0.0
U:G[T>C]T	3.0
B:G[T>C]T	0.0
N:G[T>C]T	19.0
T:G[T>G]A	1500.0
U:G[T>G]A	1629.0
B:G[T>G]A	28.0
N:G[T>G]A	4261.0
T:G[T>G]C	1258.0
U:G[T>G]C	1372.0
B:G[T>G]C	38.0
N:G[T>G]C	2660.0
T:G[T>G]G	4724.0
U:G[T>G]G	5486.0
B:G[T>G]G	112.0
N:G[T>G]G	10354.0
T:G[T>G]T	2348.0
U:G[T>G]T	3115.0
B:G[T>G]T	59.0
N:G[T>G]T	6179.0
T:T[C>A]A	198.0
U:T[C>A]A	145.0
B:T[C>A]A	2.0
N:T[C>A]A	445.0
T:T[C>A]C	0.0
U:T[C>A]C	0.0
B:T[C>A]C	0.0
N:T[C>A]C	0.0
T:T[C>A]G	0.0
U:T[C>A]G	0.0
B:T[C>A]G	0.0
N:T[C>A]G	0.0
T:T[C>A]T	0.0
U:T[C>A]T	0.0
B:T[C>A]T	0.0
N:T[C>A]T	0.0
T:T[C>G]A	0.0
U:T[C>G]A	0.0
B:T[C>G]A	0.0
N:T[C>G]A	0.0
T:T[C>G]C	6.0
U:T[C>G]C	2.0
B:T[C>G]C	0.0
N:T[C>G]C	25.0
T:T[C>G]G	23.0
U:T[C>G]G	20.0
B:T[C>G]G	0.0
N:T[C>G]G	78.0
T:T[C>G]T	2.0
U:T[C>G]T	3.0
B:T[C>G]T	0.0
N:T[C>G]T	14.0
T:T[C>T]A	1.0
U:T[C>T]A	1.0
B:T[C>T]A	0.0
N:T[C>T]A	4.0
T:T[C>T]C	0.0
U:T[C>T]C	0.0
B:T[C>T]C	0.0
N:T[C>T]C	0.0
T:T[C>T]G	0.0
U:T[C>T]G	0.0
B:T[C>T]G	0.0
N:T[C>T]G	0.0
T:T[C>T]T	59.0
U:T[C>T]T	114.0
B:T[C>T]T	1.0
N:T[C>T]T	244.0
T:T[T>A]A	11.0
U:T[T>A]A	6.0
B:T[T>A]A	0.0
N:T[T>A]A	25.0
T:T[T>A]C	2.0
U:T[T>A]C	3.0
B:T[T>A]C	0.0
N:T[T>A]C	20.0
T:T[T>A]G	0.0
U:T[T>A]G	0.0
B:T[T>A]G	0.0
N:T[T>A]G	0.0
T:T[T>A]T	0.0
U:T[T>A]T	0.0
B:T[T>A]T	0.0
N:T[T>A]T	0.0
T:T[T>C]A	0.0
U:T[T>C]A	0.0
B:T[T>C]A	0.0
N:T[T>C]A	3.0
T:T[T>C]C	1358.0
U:T[T>C]C	1285.0
B:T[T>C]C	36.0
N:T[T>C]C	3150.0
T:T[T>C]G	0.0
U:T[T>C]G	0.0
B:T[T>C]G	0.0
N:T[T>C]G	0.0
T:T[T>C]T	15.0
U:T[T>C]T	19.0
B:T[T>C]T	0.0
N:T[T>C]T	91.0
T:T[T>G]A	0.0
U:T[T>G]A	0.0
B:T[T>G]A	0.0
N:T[T>G]A	5.0
T:T[T>G]C	13.0
U:T[T>G]C	11.0
B:T[T>G]C	0.0
N:T[T>G]C	102.0
T:T[T>G]G	142.0
U:T[T>G]G	141.0
B:T[T>G]G	4.0
N:T[T>G]G	493.0
T:T[T>G]T	9.0
U:T[T>G]T	16.0
B:T[T>G]T	0.0
N:T[T>G]T	60.0

# There must be at least 1000 mutations on the strands.
# Signature and mutation type must have at least 5% of all signature mutations on the strands.
# Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1.
cancer_type	signature	mutation_type	genic_real_count	intergenic_real_count	genic_mean_sims_count	intergenic_mean_sims_count	genic_versus_intergenic_p_value	genic_versus_intergenic_q_value	percentage_of_mutations_on_strands	signature_number_of_mutations_on_strands	significant_strand	FC_REAL	FC_SIMS	FC	fold_change_1.1	fold_change_1.2	fold_change_1.3	fold_change_1.5	fold_change_1.75	fold_change_2+	Transcribed_real_count	Transcribed_mean_sims_count	Transcribed_min_sims_count	Transcribed_max_sims_count	Transcribed_sims_count_list	UnTranscribed_real_count	UnTranscribed_mean_sims_count	UnTranscribed_min_sims_count	UnTranscribed_max_sims_count	UnTranscribed_sims_count_list	NonTranscribed_real_count	NonTranscribed_mean_sims_count	NonTranscribed_min_sims_count	NonTranscribed_max_sims_count	NonTranscribed_sims_count_list
Skin-Melanoma	SBS43	C>A	1705.0	2248.0	1728.51	2224.41	0.6017698027164542	1.0	4.438	89064.0	Intergenic	1.318	1.287	1.025							1001.0	920.81	859.0	994.0	[925, 914, 904, 880, 922, 907, 948, 918, 864, 859, 931, 920, 889, 926, 899, 893, 894, 892, 916, 935, 932, 880, 908, 915, 930, 923, 925, 876, 905, 931, 968, 961, 923, 904, 950, 943, 937, 913, 922, 884, 959, 956, 929, 956, 898, 930, 951, 909, 914, 918, 895, 903, 916, 872, 929, 958, 911, 939, 929, 919, 878, 973, 910, 960, 932, 941, 901, 923, 937, 906, 937, 930, 920, 921, 947, 932, 899, 931, 926, 936, 926, 949, 937, 931, 926, 902, 879, 989, 896, 953, 913, 887, 900, 952, 994, 916, 881, 926, 921, 906]	704.0	807.7	746.0	863.0	[816, 763, 840, 801, 814, 788, 801, 829, 856, 825, 795, 804, 810, 830, 798, 814, 814, 826, 785, 790, 808, 775, 839, 797, 800, 783, 818, 855, 816, 774, 799, 772, 746, 822, 776, 800, 842, 794, 800, 788, 815, 831, 776, 778, 827, 826, 799, 823, 863, 823, 832, 829, 814, 829, 807, 840, 830, 819, 798, 809, 788, 808, 778, 806, 791, 810, 855, 801, 766, 793, 819, 807, 820, 780, 810, 784, 819, 800, 777, 810, 820, 790, 805, 816, 840, 819, 796, 806, 839, 779, 799, 814, 828, 763, 852, 807, 802, 791, 817, 794]	2248.0	2224.41	2104.0	2293.0	[2215, 2276, 2205, 2273, 2211, 2263, 2201, 2210, 2229, 2268, 2235, 2219, 2251, 2195, 2257, 2249, 2246, 2237, 2258, 2230, 2216, 2293, 2209, 2236, 2226, 2251, 2212, 2214, 2233, 2245, 2186, 2224, 2281, 2229, 2226, 2209, 2171, 2243, 2232, 2278, 2179, 2173, 2254, 2215, 2225, 2186, 2207, 2224, 2176, 2218, 2226, 2222, 2221, 2250, 2221, 2161, 2219, 2196, 2227, 2227, 2279, 2175, 2268, 2188, 2230, 2204, 2198, 2230, 2250, 2249, 2201, 2217, 2210, 2244, 2197, 2236, 2232, 2215, 2251, 2211, 2207, 2220, 2208, 2198, 2186, 2229, 2279, 2164, 2220, 2224, 2235, 2251, 2228, 2238, 2104, 2228, 2270, 2238, 2209, 2251]
Skin-Melanoma	SBS43	C>G	1914.0	2037.0	1928.68	2014.81	0.6852492025802012	1.0	4.436	89064.0	Intergenic	1.064	1.045	1.019							921.0	956.88	893.0	1030.0	[977, 978, 1004, 976, 937, 978, 934, 959, 977, 1013, 954, 956, 973, 947, 931, 942, 993, 939, 996, 952, 972, 973, 978, 903, 952, 925, 970, 956, 957, 959, 955, 1002, 953, 945, 966, 969, 938, 899, 953, 942, 997, 967, 963, 960, 940, 987, 959, 960, 893, 931, 979, 983, 955, 951, 980, 975, 936, 948, 986, 943, 940, 961, 1030, 956, 937, 973, 910, 930, 940, 996, 925, 929, 935, 951, 1012, 915, 974, 1000, 925, 921, 947, 938, 980, 970, 970, 965, 926, 926, 898, 979, 932, 953, 1000, 923, 985, 959, 950, 968, 946, 937]	993.0	971.8	911.0	1023.0	[964, 955, 957, 953, 1002, 949, 986, 1023, 957, 937, 982, 993, 947, 980, 995, 960, 983, 955, 995, 989, 950, 985, 976, 975, 939, 954, 961, 948, 994, 911, 991, 975, 1021, 955, 1016, 950, 1003, 970, 990, 998, 972, 983, 962, 977, 969, 955, 977, 956, 981, 1006, 936, 952, 980, 1005, 1016, 947, 986, 1013, 936, 964, 993, 976, 949, 981, 1008, 954, 979, 1011, 974, 948, 942, 982, 1000, 968, 939, 959, 943, 945, 941, 989, 972, 992, 955, 921, 982, 923, 976, 963, 1002, 1000, 997, 968, 942, 994, 983, 967, 974, 962, 979, 950]	2037.0	2014.81	1953.0	2080.0	[2021, 2016, 1986, 2018, 2003, 2016, 2020, 1962, 2014, 1988, 2007, 1993, 2012, 2024, 2021, 2041, 1967, 2048, 1962, 2006, 2018, 1984, 1997, 2061, 2042, 2066, 2011, 2040, 1994, 2075, 2002, 1976, 1969, 2047, 1962, 2027, 2002, 2077, 1997, 2009, 1968, 1997, 2017, 2000, 2030, 2006, 2004, 2028, 2066, 2000, 2031, 2013, 2015, 1992, 1953, 2025, 2021, 1983, 2017, 2034, 2009, 2005, 1963, 1997, 1997, 2013, 2048, 2000, 2024, 1989, 2080, 2021, 2003, 2021, 1994, 2066, 2033, 2006, 2077, 2032, 2027, 2016, 2008, 2052, 1992, 2047, 2039, 2058, 2045, 1968, 2018, 2017, 2007, 2028, 1984, 2016, 2019, 2011, 2018, 2052]
Skin-Melanoma	SBS43	C>T	146.0	156.0	134.35	167.33	0.3694383612903276	0.7702224853698482	0.339	89064.0	Intergenic	1.068	1.245	0.858							57.0	65.06	50.0	83.0	[69, 66, 73, 52, 69, 70, 58, 72, 65, 61, 69, 64, 61, 60, 68, 76, 59, 70, 68, 82, 60, 65, 60, 67, 61, 71, 81, 63, 64, 61, 56, 68, 55, 66, 64, 50, 63, 67, 62, 75, 75, 60, 63, 58, 58, 57, 68, 67, 68, 66, 64, 66, 56, 59, 59, 81, 68, 64, 56, 67, 70, 60, 73, 78, 67, 66, 61, 57, 61, 66, 66, 67, 75, 57, 60, 62, 67, 61, 57, 65, 77, 79, 67, 59, 62, 73, 54, 65, 63, 64, 56, 69, 66, 55, 59, 83, 58, 74, 74, 62]	89.0	69.29	53.0	84.0	[66, 73, 60, 74, 61, 73, 76, 55, 61, 74, 78, 67, 59, 75, 62, 75, 72, 75, 70, 70, 69, 63, 64, 75, 58, 76, 56, 75, 66, 53, 69, 68, 84, 67, 76, 69, 58, 69, 71, 84, 55, 67, 67, 72, 76, 79, 58, 67, 70, 69, 68, 57, 60, 79, 74, 67, 75, 75, 82, 62, 74, 80, 63, 65, 66, 80, 69, 70, 70, 66, 80, 68, 61, 69, 78, 70, 76, 71, 82, 66, 66, 55, 54, 67, 72, 62, 70, 73, 66, 78, 65, 69, 68, 82, 71, 70, 70, 77, 68, 77]	156.0	167.33	142.0	188.0	[167, 164, 168, 174, 172, 159, 169, 175, 177, 166, 154, 169, 181, 166, 173, 153, 169, 158, 164, 150, 172, 173, 177, 159, 181, 158, 164, 165, 170, 188, 176, 168, 161, 170, 162, 183, 181, 166, 169, 142, 172, 175, 170, 171, 169, 164, 175, 167, 163, 167, 171, 178, 185, 162, 167, 152, 161, 162, 163, 172, 157, 163, 167, 159, 171, 156, 171, 174, 171, 168, 157, 169, 166, 175, 167, 168, 158, 168, 162, 173, 160, 170, 180, 175, 169, 165, 178, 165, 172, 160, 179, 164, 167, 164, 172, 148, 174, 150, 161, 161]
Skin-Melanoma	SBS43	T>A	1217.0	1714.0	1237.71	1695.48	0.6149943959888156	1.0	3.291	89064.0	Intergenic	1.408	1.37	1.028							735.0	620.22	568.0	681.0	[604, 632, 598, 590, 631, 619, 593, 591, 610, 620, 569, 605, 609, 609, 597, 603, 638, 584, 625, 614, 586, 620, 629, 645, 602, 628, 584, 598, 614, 612, 616, 603, 664, 592, 620, 681, 618, 673, 604, 667, 614, 622, 633, 596, 616, 617, 638, 665, 605, 640, 581, 639, 568, 637, 581, 627, 619, 631, 669, 666, 628, 613, 611, 611, 607, 616, 609, 641, 640, 608, 594, 635, 619, 629, 609, 618, 661, 621, 599, 637, 628, 641, 644, 630, 631, 644, 616, 649, 633, 646, 621, 630, 618, 648, 589, 664, 599, 609, 576, 639]	482.0	617.49	556.0	668.0	[604, 638, 590, 634, 642, 632, 642, 616, 621, 599, 626, 615, 627, 630, 615, 613, 631, 611, 576, 595, 605, 597, 626, 593, 655, 640, 565, 607, 578, 601, 598, 631, 579, 644, 599, 611, 596, 594, 625, 556, 635, 593, 623, 600, 619, 620, 604, 624, 626, 607, 633, 599, 650, 652, 606, 639, 659, 613, 627, 628, 617, 613, 667, 629, 612, 620, 605, 610, 617, 668, 625, 624, 614, 661, 593, 608, 626, 611, 635, 593, 654, 640, 623, 605, 610, 600, 628, 565, 619, 655, 610, 630, 619, 628, 616, 595, 614, 623, 638, 615]	1714.0	1695.48	1635.0	1786.0	[1721, 1667, 1747, 1712, 1661, 1688, 1693, 1723, 1703, 1715, 1735, 1710, 1691, 1695, 1718, 1716, 1659, 1738, 1731, 1724, 1739, 1720, 1677, 1693, 1680, 1665, 1786, 1725, 1739, 1721, 1728, 1699, 1684, 1699, 1717, 1647, 1715, 1664, 1706, 1709, 1685, 1716, 1674, 1735, 1702, 1692, 1691, 1645, 1701, 1691, 1725, 1691, 1717, 1646, 1741, 1667, 1659, 1695, 1635, 1641, 1693, 1703, 1654, 1692, 1712, 1694, 1716, 1684, 1675, 1659, 1714, 1674, 1701, 1643, 1732, 1712, 1650, 1707, 1695, 1702, 1653, 1655, 1664, 1697, 1699, 1687, 1690, 1715, 1681, 1635, 1705, 1675, 1699, 1660, 1726, 1673, 1718, 1697, 1719, 1679]
Skin-Melanoma	SBS43	T>C	12857.0	13792.0	11911.6	14690.24	1.0576487353901207e-15	7.994975490731608e-15	29.921	89064.0	Intergenic	1.073	1.233	0.87							6802.0	5940.28	5788.0	6102.0	[5839, 6022, 5974, 5788, 5885, 6050, 5849, 6031, 5972, 5939, 5923, 6054, 6018, 5926, 5986, 5919, 5900, 5890, 5892, 5936, 5907, 5863, 5954, 5905, 6013, 5918, 5907, 5897, 6055, 6068, 5873, 5794, 5953, 5934, 5917, 5996, 5950, 5986, 5991, 6020, 5921, 5918, 5929, 5929, 5906, 5920, 5910, 5841, 5884, 5893, 5954, 5845, 6087, 5941, 5957, 5830, 5890, 5909, 6092, 5883, 5910, 5838, 6102, 6029, 5944, 5904, 5984, 5926, 5873, 5866, 6013, 5930, 5866, 5988, 5929, 6007, 5982, 5912, 5906, 6083, 5978, 5826, 5988, 5999, 5976, 5976, 5939, 6033, 5937, 5866, 5862, 6052, 5952, 5886, 5899, 5941, 5872, 5963, 5994, 5964]	6055.0	5971.32	5843.0	6143.0	[5987, 5989, 5882, 6048, 5951, 5960, 5932, 6006, 5896, 5956, 5962, 5867, 6062, 5917, 6037, 6052, 6064, 5977, 5956, 5868, 5913, 6019, 5953, 5998, 5930, 6092, 6017, 5899, 5947, 5872, 5899, 6081, 5921, 5911, 5946, 6021, 5904, 5963, 6136, 5941, 5973, 5919, 5987, 5907, 6062, 5945, 5921, 6077, 5982, 5937, 5957, 6052, 5870, 5869, 5981, 5929, 6143, 6010, 5966, 5988, 6067, 5989, 5944, 5902, 5863, 6016, 5915, 5988, 5947, 6025, 5942, 6054, 5995, 5913, 5925, 6015, 5948, 6009, 6038, 5856, 5989, 5873, 6012, 5843, 6045, 6045, 5999, 5899, 6036, 6038, 6043, 5939, 5990, 6123, 5878, 5867, 6037, 5976, 5965, 5977]	13792.0	14690.24	14492.0	14894.0	[14759, 14578, 14726, 14769, 14760, 14584, 14815, 14571, 14731, 14720, 14699, 14692, 14535, 14739, 14594, 14612, 14657, 14739, 14757, 14798, 14803, 14712, 14690, 14680, 14654, 14597, 14664, 14808, 14606, 14667, 14836, 14735, 14705, 14755, 14732, 14606, 14723, 14664, 14492, 14658, 14714, 14754, 14701, 14760, 14628, 14724, 14762, 14672, 14728, 14765, 14684, 14703, 14638, 14775, 14669, 14837, 14568, 14680, 14541, 14723, 14619, 14774, 14551, 14665, 14787, 14691, 14705, 14680, 14781, 14722, 14641, 14636, 14746, 14706, 14743, 14588, 14690, 14681, 14662, 14669, 14636, 14894, 14607, 14744, 14613, 14596, 14657, 14683, 14644, 14709, 14706, 14620, 14656, 14597, 14808, 14803, 14707, 14655, 14635, 14669]
Skin-Melanoma	SBS43	T>G	24489.0	26789.0	22937.94	28274.99	1.6815364427130233e-21	1.4440002537309937e-20	57.574	89064.0	Intergenic	1.094	1.233	0.887							11301.0	10593.3	10368.0	10843.0	[10571, 10580, 10626, 10681, 10583, 10672, 10516, 10568, 10583, 10458, 10545, 10417, 10448, 10631, 10577, 10632, 10752, 10843, 10636, 10709, 10630, 10500, 10768, 10653, 10527, 10637, 10714, 10554, 10680, 10708, 10577, 10639, 10588, 10682, 10681, 10512, 10634, 10528, 10739, 10572, 10551, 10610, 10464, 10699, 10604, 10526, 10555, 10752, 10529, 10739, 10589, 10541, 10649, 10736, 10510, 10501, 10699, 10588, 10644, 10434, 10571, 10455, 10637, 10486, 10565, 10722, 10589, 10506, 10529, 10584, 10533, 10505, 10653, 10723, 10507, 10739, 10710, 10566, 10633, 10388, 10576, 10510, 10558, 10567, 10656, 10524, 10717, 10761, 10617, 10642, 10674, 10566, 10368, 10455, 10581, 10552, 10447, 10434, 10479, 10574]	13188.0	12344.64	12083.0	12618.0	[12373, 12407, 12490, 12417, 12295, 12328, 12371, 12323, 12369, 12245, 12347, 12423, 12573, 12384, 12618, 12099, 12343, 12295, 12115, 12244, 12453, 12408, 12309, 12387, 12238, 12359, 12233, 12458, 12222, 12248, 12311, 12290, 12259, 12211, 12371, 12545, 12104, 12229, 12083, 12311, 12311, 12425, 12323, 12327, 12276, 12558, 12276, 12313, 12298, 12222, 12396, 12333, 12282, 12221, 12422, 12281, 12282, 12514, 12217, 12436, 12443, 12289, 12224, 12533, 12236, 12341, 12114, 12381, 12501, 12454, 12432, 12397, 12422, 12445, 12279, 12265, 12212, 12173, 12390, 12419, 12467, 12443, 12305, 12453, 12449, 12278, 12406, 12195, 12553, 12379, 12388, 12512, 12332, 12490, 12290, 12362, 12300, 12305, 12428, 12378]	26789.0	28274.99	28034.0	28518.0	[28285, 28223, 28102, 28120, 28337, 28203, 28311, 28312, 28249, 28510, 28318, 28395, 28227, 28201, 28034, 28468, 28134, 28072, 28454, 28271, 28116, 28278, 28157, 28172, 28465, 28229, 28273, 28213, 28315, 28251, 28309, 28293, 28355, 28328, 28191, 28167, 28489, 28467, 28360, 28335, 28342, 28160, 28410, 28190, 28338, 28139, 28382, 28146, 28383, 28252, 28215, 28337, 28258, 28261, 28286, 28411, 28219, 28106, 28333, 28353, 28187, 28474, 28341, 28209, 28438, 28145, 28518, 28312, 28160, 28184, 28240, 28312, 28144, 28087, 28440, 28230, 28286, 28452, 28181, 28382, 28161, 28253, 28353, 28202, 28128, 28392, 28095, 28275, 28057, 28195, 28129, 28166, 28506, 28287, 28334, 28275, 28438, 28468, 28311, 28242]

Summary across all cancer types
signature	mutation_type	strand	fold_change_1.1	len(fold_change_1.1_cancer_types)	fold_change_1.2	len(fold_change_1.2_cancer_types)	fold_change_1.3	len(fold_change_1.3_cancer_types)	fold_change_1.5	len(fold_change_1.5_cancer_types)	fold_change_1.75	len(fold_change_1.75_cancer_types)	fold_change_2+	len(fold_change_2+_cancer_types)	all_cancer_types_list	len(all_cancer_types_list)	avg_fold_change
SBS43	T>C	Intergenic	[]	0	[]	0	[]	0	[]	0	[]	0	[]	0	['Skin-Melanoma']	1	
SBS43	T>G	Intergenic	[]	0	[]	0	[]	0	[]	0	[]	0	[]	0	['Skin-Melanoma']	1