# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. signature cancer_type cutoff number_of_mutations average_probability file_name pearson_corr pearson_p_value pearson_q_value real_average_number_of_overlaps sims_average_number_of_overlaps avg_real_signal sim_data_avg_signal fold_change real_average_signal_array sims_average_signal_array SBS43 Skin-Melanoma 0.5 88495 0.911 SBS43_ENCFF054PUP_lower-leg-skin_Normal_CTCF-human_AverageSignalArray.txt 39.81 12.949 22.935 24.421 0.939 [24.59, 24.59, 24.59, 24.59, 24.657, 24.657, 24.657, 24.657, 24.657, 24.657, 24.657, 24.464, 24.464, 24.464, 24.464, 24.464, 24.615, 24.394, 24.394, 24.4, 24.404, 24.404, 24.404, 24.404, 24.3, 24.3, 24.3, 24.3, 24.3, 24.3, 24.3, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.247, 24.445, 24.377, 24.377, 24.377, 24.377, 24.377, 24.822, 24.822, 24.578, 24.568, 24.568, 24.568, 24.568, 24.568, 24.568, 24.506, 24.506, 24.47, 24.384, 24.384, 24.335, 24.335, 24.335, 24.256, 24.256, 24.256, 24.281, 24.281, 24.4, 24.4, 24.445, 24.445, 24.445, 24.361, 24.361, 24.361, 24.361, 24.361, 24.361, 24.361, 24.361, 24.361, 24.361, 24.361, 24.222, 24.222, 24.222, 24.222, 24.378, 24.378, 24.328, 24.328, 24.328, 24.328, 24.328, 24.358, 24.358, 24.358, 24.358, 24.309, 24.309, 23.994, 23.994, 23.979, 23.979, 23.979, 23.979, 23.953, 23.944, 23.944, 23.944, 23.944, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.919, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.875, 23.759, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.449, 23.305, 23.305, 23.305, 23.305, 23.305, 23.305, 23.173, 23.173, 23.173, 23.173, 23.173, 23.173, 23.173, 23.173, 23.173, 23.173, 23.173, 23.124, 23.124, 23.124, 23.16, 23.16, 23.16, 23.16, 22.984, 22.984, 22.984, 22.974, 22.974, 22.865, 22.865, 22.865, 22.865, 22.865, 22.746, 22.746, 22.893, 22.893, 23.041, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.147, 23.123, 23.123, 23.123, 23.123, 23.123, 23.123, 23.064, 23.143, 23.143, 23.023, 23.023, 23.023, 23.129, 23.129, 23.129, 23.129, 23.129, 23.129, 23.129, 23.129, 23.129, 23.129, 23.129, 23.556, 23.556, 23.556, 23.556, 23.556, 23.556, 23.672, 23.672, 23.672, 23.672, 23.672, 23.553, 23.452, 23.561, 23.561, 23.707, 23.707, 23.564, 23.564, 23.753, 23.753, 23.753, 23.753, 23.753, 23.753, 23.753, 23.821, 23.821, 23.821, 23.821, 23.821, 23.821, 23.821, 23.865, 23.865, 23.865, 23.865, 23.865, 23.925, 23.925, 23.81, 23.81, 23.81, 23.81, 23.81, 23.796, 24.007, 24.007, 24.007, 24.007, 24.007, 24.007, 24.007, 24.007, 24.007, 23.861, 23.861, 23.861, 23.861, 23.861, 23.861, 23.861, 23.632, 23.632, 23.536, 23.536, 23.536, 23.536, 23.025, 23.025, 23.251, 23.221, 23.221, 23.221, 23.221, 23.108, 23.108, 23.139, 23.139, 23.196, 23.272, 23.116, 23.141, 23.101, 23.001, 22.96, 22.928, 22.928, 22.928, 22.885, 22.84, 22.84, 22.802, 22.802, 22.802, 22.863, 22.863, 22.863, 22.863, 22.863, 22.762, 22.762, 22.762, 22.762, 22.762, 22.762, 22.762, 22.762, 22.762, 22.681, 22.65, 22.65, 22.534, 22.534, 22.534, 22.534, 22.534, 22.534, 22.534, 22.534, 22.534, 22.539, 22.539, 22.622, 22.622, 22.622, 22.622, 22.622, 22.622, 22.612, 22.612, 22.612, 22.612, 22.612, 22.602, 22.602, 22.602, 22.602, 22.602, 22.602, 22.602, 22.729, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.442, 22.414, 22.494, 22.494, 22.494, 22.494, 22.613, 22.613, 22.613, 22.613, 22.613, 22.613, 22.613, 22.613, 22.613, 22.59, 22.59, 22.59, 22.59, 22.59, 22.59, 22.59, 22.59, 22.59, 22.59, 22.59, 22.59, 22.777, 22.777, 22.777, 22.777, 22.777, 22.777, 22.923, 22.923, 22.923, 22.923, 23.094, 23.094, 23.094, 23.094, 23.094, 23.094, 23.094, 23.094, 23.094, 23.094, 23.066, 23.066, 23.066, 23.066, 23.066, 23.066, 23.066, 23.075, 23.075, 23.158, 23.158, 23.158, 23.158, 23.04, 23.115, 23.115, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.024, 23.042, 23.042, 23.042, 23.042, 23.042, 23.042, 23.042, 23.042, 23.042, 23.042, 23.042, 23.042, 22.953, 22.953, 22.865, 22.865, 22.865, 22.865, 22.865, 22.781, 22.781, 22.781, 22.781, 22.412, 22.543, 22.543, 22.543, 22.543, 22.47, 22.47, 22.47, 22.47, 22.47, 22.47, 22.536, 22.597, 22.597, 22.597, 22.441, 22.441, 22.541, 22.541, 22.541, 22.692, 22.692, 22.692, 22.692, 22.692, 22.692, 22.767, 22.767, 22.946, 22.946, 22.946, 22.946, 22.946, 22.946, 22.946, 22.946, 22.822, 22.822, 22.748, 22.748, 22.814, 22.814, 22.814, 22.814, 22.814, 22.814, 22.566, 22.566, 22.566, 22.566, 22.566, 22.566, 22.566, 22.566, 22.566, 23.028, 23.028, 23.028, 23.028, 23.028, 23.028, 23.028, 23.028, 23.028, 23.198, 23.198, 23.198, 23.198, 23.198, 23.198, 23.198, 23.198, 23.198, 23.198, 23.198, 23.301, 23.301, 23.301, 23.301, 23.255, 23.255, 23.401, 23.401, 23.448, 23.562, 23.694, 23.756, 23.84, 23.84, 23.84, 23.84, 23.84, 24.067, 24.067, 24.067, 24.067, 24.067, 24.067, 24.067, 24.067, 24.214, 24.214, 24.214, 24.214, 24.214, 24.214, 24.214, 24.214, 24.214, 24.357, 24.454, 24.454, 24.677, 24.677, 24.677, 24.677, 24.677, 24.677, 24.677, 24.677, 24.677, 24.761, 24.761, 24.733, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.197, 25.128, 26.048, 26.048, 26.048, 26.048, 26.048, 26.048, 26.048, 26.048, 26.048, 25.914, 25.914, 25.914, 26.332, 26.332, 26.332, 26.332, 26.53, 26.284, 26.284, 26.284, 26.284, 26.669, 26.669, 26.669, 26.669, 26.669, 26.669, 26.669, 26.669, 26.669, 26.878, 26.878, 26.878, 26.878, 26.878, 26.878, 26.878, 26.878, 26.878, 26.878, 26.878, 26.878, 26.73, 26.73, 26.73, 26.73, 26.73, 26.73, 26.631, 26.631, 26.631, 26.631, 25.77, 25.77, 25.77, 25.77, 25.77, 25.77, 25.77, 25.77, 26.089, 26.089, 26.089, 26.089, 26.089, 26.408, 26.408, 26.408, 26.408, 26.408, 26.408, 26.408, 26.408, 26.408, 26.726, 27.109, 27.109, 27.109, 27.248, 27.248, 27.248, 27.248, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.763, 26.874, 26.874, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.764, 26.495, 26.495, 26.495, 26.495, 26.495, 26.495, 25.711, 25.711, 25.711, 25.711, 25.711, 24.928, 24.928, 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23.731, 23.188, 23.188, 23.188, 23.188, 23.188, 23.188, 23.188, 23.188, 23.188, 23.188, 23.188, 23.176, 23.176, 23.176, 23.176, 23.176, 23.176, 23.335, 22.984, 22.984, 22.984, 23.023, 23.023, 23.023, 23.104, 23.104, 23.104, 23.118, 23.109, 23.109, 22.583, 22.635, 22.537, 22.537, 22.537, 22.552, 22.552, 22.552, 22.552, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 22.025, 21.971, 21.971, 21.971, 21.971, 21.971, 21.971, 21.971, 21.971, 21.971] [24.39, 24.391, 24.401, 24.397, 24.388, 24.384, 24.381, 24.37, 24.363, 24.359, 24.372, 24.384, 24.332, 24.336, 24.324, 24.341, 24.382, 24.376, 24.377, 24.356, 24.385, 24.384, 24.387, 24.385, 24.382, 24.368, 24.385, 24.4, 24.391, 24.395, 24.426, 24.418, 24.408, 24.399, 24.403, 24.402, 24.389, 24.398, 24.408, 24.392, 24.398, 24.398, 24.409, 24.411, 24.409, 24.424, 24.429, 24.447, 24.472, 24.478, 24.479, 24.481, 24.477, 24.493, 24.467, 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