# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	real_number_of_mutations_array	real_normalized_mutations_density_array	simulations_means_normalized_mutations_density_array	cancer_type_slope	replication_timing_diff_btw_max_and_min	abs_replication_timing_diff_btw_medians	cancer_type_decision	cutoff	number_of_mutations	average_probability	num_of_tissues_with_increasing_decision	num_of_tissues_with_flat_decision	num_of_tissues_with_decreasing_decision	num_of_all_tissues
SBS40	ALL	[260, 278, 302, 424, 386, 507, 653, 755, 1052, 483]	[0.211, 0.226, 0.246, 0.345, 0.314, 0.414, 0.534, 0.619, 0.864, 1.0]	[0.814, 0.863, 0.88, 0.902, 0.899, 0.894, 0.902, 0.902, 0.916, 0.985]	0.085	0.789	0.638	INC	0.53	5115	0.753				
SBS40	Bladder-TCC	[1322, 1373, 1485, 1647, 1964, 2328, 2597, 3065, 3853, 1854]	[0.276, 0.287, 0.31, 0.344, 0.41, 0.488, 0.544, 0.644, 0.812, 1.0]	[0.906, 0.939, 0.955, 0.97, 0.974, 0.967, 0.969, 0.978, 0.975, 0.961]	0.076	0.724	0.525	INC	0.64	21506	0.759				
SBS40	Bone-Osteosarc	[5991, 6588, 7480, 8426, 9940, 11374, 12640, 14034, 16489, 7156]	[0.324, 0.356, 0.405, 0.456, 0.538, 0.618, 0.686, 0.764, 0.9, 1.0]	[0.919, 0.941, 0.954, 0.965, 0.969, 0.967, 0.971, 0.977, 0.993, 0.991]	0.075	0.676	0.543	INC	0.5	100326	0.753				
SBS40	CNS-GBM	[6408, 7354, 9304, 10649, 12555, 14856, 16967, 20949, 27343, 12960]	[0.19, 0.218, 0.276, 0.316, 0.372, 0.441, 0.504, 0.625, 0.82, 1.0]	[0.774, 0.797, 0.84, 0.86, 0.872, 0.902, 0.907, 0.921, 0.942, 1.0]	0.084	0.81	0.602	INC	0.5	139818	0.755				
SBS40	CNS-Medullo	[3990, 4275, 4861, 5265, 5615, 6080, 7133, 8085, 9906, 4853]	[0.316, 0.338, 0.385, 0.417, 0.444, 0.482, 0.566, 0.644, 0.793, 1.0]	[0.808, 0.816, 0.841, 0.847, 0.86, 0.894, 0.912, 0.926, 0.951, 1.0]	0.067	0.684	0.455	INC	0.61	60375	0.751				
SBS40	CNS-PiloAstro	[233, 247, 227, 286, 325, 352, 392, 479, 636, 304]	[0.295, 0.312, 0.287, 0.361, 0.41, 0.446, 0.497, 0.609, 0.813, 1.0]	[0.72, 0.74, 0.766, 0.781, 0.792, 0.843, 0.857, 0.875, 0.916, 0.99]	0.072	0.713	0.518	INC	0.63	3508	0.752				
SBS40	ColoRect-AdenoCA	[12507, 14984, 17382, 20814, 25760, 31447, 36718, 41912, 48298, 20745]	[0.233, 0.28, 0.324, 0.389, 0.481, 0.589, 0.688, 0.787, 0.909, 1.0]	[0.828, 0.899, 0.934, 0.949, 0.973, 0.975, 0.982, 0.997, 0.994, 0.985]	0.089	0.767	0.63	INC	0.51	271455	0.75				
SBS40	Ewings	[462, 488, 493, 525, 655, 806, 857, 959, 1149, 513]	[0.349, 0.368, 0.372, 0.397, 0.495, 0.611, 0.649, 0.729, 0.875, 1.0]	[0.897, 0.939, 0.941, 0.948, 0.95, 0.945, 0.945, 0.952, 0.948, 0.948]	0.073	0.651	0.506	INC	0.61	6943	0.75				
SBS40	Head-SCC	[4302, 4669, 5385, 6613, 8310, 10039, 11673, 13593, 16062, 7224]	[0.231, 0.25, 0.289, 0.355, 0.446, 0.54, 0.628, 0.733, 0.868, 1.0]	[0.904, 0.949, 0.971, 0.98, 0.984, 0.983, 0.988, 0.991, 0.981, 0.981]	0.087	0.769	0.618	INC	0.63	88002	0.756				
SBS40	Kidney-RCC	[79928, 78996, 80314, 82028, 86783, 91001, 96110, 100028, 107284, 44725]	[0.692, 0.684, 0.695, 0.711, 0.752, 0.791, 0.835, 0.872, 0.937, 1.0]	[0.999, 0.993, 0.997, 0.996, 0.987, 0.985, 0.983, 0.979, 0.969, 0.949]	0.035	0.316	0.245	INC	0.5	848413	0.841				
SBS40	Lung-AdenoCA	[8383, 10117, 11700, 13020, 14568, 17250, 19658, 23887, 29529, 13993]	[0.236, 0.285, 0.33, 0.367, 0.412, 0.487, 0.555, 0.681, 0.841, 1.0]	[0.927, 0.948, 0.957, 0.964, 0.969, 0.973, 0.974, 0.97, 0.966, 1.0]	0.08	0.764	0.557	INC	0.56	162576	0.752				
SBS40	Panc-AdenoCA	[20639, 22016, 24304, 28281, 33853, 40643, 46704, 53591, 64055, 27105]	[0.295, 0.315, 0.347, 0.404, 0.484, 0.583, 0.67, 0.771, 0.923, 1.0]	[0.923, 0.955, 0.969, 0.981, 0.985, 0.984, 0.99, 0.999, 0.994, 0.978]	0.083	0.705	0.608	INC	0.6	361638	0.756				
SBS40	Prost-AdenoCA	[19821, 20493, 22716, 24735, 28304, 32417, 36688, 42741, 48298, 20977]	[0.366, 0.378, 0.419, 0.457, 0.523, 0.6, 0.68, 0.794, 0.899, 1.0]	[0.937, 0.973, 0.985, 0.988, 0.989, 0.994, 0.996, 0.995, 0.981, 0.982]	0.073	0.634	0.521	INC	0.63	299068	0.752				
SBS40	SoftTissue-Leiomyo	[4176, 4662, 4993, 5728, 6481, 7215, 7762, 8604, 9915, 4099]	[0.394, 0.44, 0.472, 0.542, 0.613, 0.684, 0.736, 0.818, 0.945, 1.0]	[0.933, 0.95, 0.964, 0.977, 0.973, 0.973, 0.971, 0.978, 0.996, 0.983]	0.069	0.606	0.504	INC	0.5	63694	0.78				
SBS40	Stomach-AdenoCA	[3774, 4243, 4909, 5573, 6726, 8024, 9174, 10690, 12798, 5448]	[0.268, 0.302, 0.349, 0.397, 0.478, 0.572, 0.654, 0.765, 0.917, 1.0]	[0.881, 0.931, 0.954, 0.968, 0.972, 0.968, 0.97, 0.978, 0.995, 0.981]	0.084	0.732	0.616	INC	0.61	71531	0.751				
SBS40	Uterus-AdenoCA	[11146, 11539, 12633, 13853, 16391, 19574, 20886, 23089, 25714, 11780]	[0.37, 0.383, 0.42, 0.461, 0.546, 0.653, 0.698, 0.775, 0.865, 1.0]	[0.918, 0.942, 0.956, 0.97, 0.978, 0.987, 0.978, 0.971, 0.993, 0.994]	0.071	0.63	0.482	INC	0.5	166610	0.75				
SBS40	Biliary-AdenoCA	[6671, 7229, 8170, 9420, 11606, 13732, 15930, 17586, 21097, 9723]	[0.266, 0.288, 0.325, 0.376, 0.462, 0.549, 0.637, 0.705, 0.847, 1.0]	[0.91, 0.958, 0.974, 0.984, 0.985, 0.983, 0.99, 0.993, 0.986, 0.984]	0.081	0.734	0.559	INC	0.62	121298	0.754				
SBS40	Bone-Epith	[588, 644, 759, 903, 1026, 1168, 1257, 1499, 1686, 700]	[0.325, 0.356, 0.42, 0.5, 0.568, 0.648, 0.698, 0.835, 0.941, 1.0]	[0.9, 0.923, 0.94, 0.949, 0.946, 0.949, 0.953, 0.962, 0.968, 0.95]	0.078	0.675	0.584	INC	0.55	10262	0.752				
SBS40	Breast-Cancer	[616, 545, 578, 637, 632, 703, 735, 839, 958, 422]	[0.565, 0.5, 0.53, 0.585, 0.58, 0.647, 0.677, 0.775, 0.887, 1.0]	[0.965, 0.933, 0.921, 0.922, 0.925, 0.916, 0.913, 0.917, 0.956, 0.953]	0.05	0.5	0.356	INC	0.5	6665	0.795				
SBS40	Cervix-Cancer	[161, 185, 199, 284, 372, 412, 444, 584, 676, 334]	[0.189, 0.217, 0.233, 0.333, 0.437, 0.485, 0.523, 0.691, 0.802, 1.0]	[0.777, 0.821, 0.854, 0.878, 0.893, 0.915, 0.904, 0.902, 0.94, 0.968]	0.087	0.811	0.586	INC	0.67	3651	0.757				
SBS40	Eso-AdenoCA	[28421, 30549, 35436, 42032, 53610, 66457, 77008, 88573, 107086, 48015]	[0.229, 0.246, 0.286, 0.339, 0.433, 0.538, 0.623, 0.719, 0.871, 1.0]	[0.884, 0.951, 0.972, 0.979, 0.985, 0.988, 0.995, 0.999, 0.987, 0.989]	0.087	0.771	0.625	INC	0.5	577751	0.779				
SBS40	ESCC	[18866, 21652, 25222, 29738, 37168, 45497, 52642, 58426, 69683, 31962]	[0.229, 0.262, 0.305, 0.361, 0.451, 0.553, 0.64, 0.712, 0.851, 1.0]	[0.88, 0.944, 0.973, 0.982, 0.986, 0.992, 0.995, 0.994, 0.99, 0.996]	0.085	0.771	0.589	INC	0.59	392469	0.755				
SBS40	Kidney-ChRCC	[4183, 4177, 4493, 4780, 5348, 5749, 6232, 6731, 7847, 3204]	[0.506, 0.505, 0.543, 0.578, 0.647, 0.697, 0.756, 0.819, 0.956, 1.0]	[0.957, 0.957, 0.965, 0.97, 0.974, 0.976, 0.97, 0.985, 0.989, 0.974]	0.058	0.495	0.451	INC	0.5	52829	0.769				
SBS40	Liver-HCC	[8801, 9139, 9302, 10149, 11275, 12904, 14836, 18161, 22635, 10183]	[0.342, 0.355, 0.361, 0.395, 0.439, 0.504, 0.581, 0.713, 0.886, 1.0]	[0.966, 0.977, 0.989, 0.993, 0.993, 0.984, 0.971, 0.975, 0.967, 0.976]	0.073	0.658	0.531	INC	0.64	127619	0.754				
SBS40	Lymph-BNHL	[12775, 12679, 13695, 15888, 19010, 23139, 30622, 39363, 54217, 26422]	[0.19, 0.188, 0.204, 0.237, 0.283, 0.346, 0.458, 0.59, 0.814, 1.0]	[0.805, 0.851, 0.875, 0.897, 0.905, 0.917, 0.93, 0.924, 0.926, 1.0]	0.087	0.812	0.625	INC	0.57	248652	0.752				
SBS40	Lymph-CLL	[160, 162, 202, 227, 243, 323, 415, 525, 786, 375]	[0.167, 0.17, 0.212, 0.238, 0.255, 0.34, 0.437, 0.555, 0.832, 1.0]	[0.698, 0.761, 0.797, 0.818, 0.843, 0.855, 0.885, 0.898, 0.894, 0.988]	0.088	0.833	0.662	INC	0.67	3480	0.754				
SBS40	Ovary-AdenoCA	[8899, 9430, 10224, 11834, 12741, 14697, 15255, 16637, 17829, 7939]	[0.439, 0.465, 0.504, 0.584, 0.63, 0.728, 0.757, 0.828, 0.89, 1.0]	[0.938, 0.963, 0.98, 0.987, 0.987, 0.987, 0.985, 0.981, 0.985, 0.99]	0.062	0.561	0.425	INC	0.6	125509	0.754				
SBS40	Panc-Endocrine	[553, 649, 737, 846, 1092, 1264, 1497, 1714, 2120, 951]	[0.225, 0.264, 0.3, 0.345, 0.445, 0.516, 0.612, 0.702, 0.871, 1.0]	[0.818, 0.877, 0.892, 0.919, 0.928, 0.921, 0.917, 0.932, 0.981, 0.975]	0.085	0.775	0.606	INC	0.5	11428	0.798				
SBS40	Skin-Melanoma	[9133, 9366, 10538, 11778, 13036, 15475, 17863, 21414, 25554, 10965]	[0.321, 0.329, 0.37, 0.413, 0.458, 0.545, 0.63, 0.757, 0.903, 1.0]	[0.975, 0.976, 0.978, 0.979, 0.977, 0.983, 0.987, 0.985, 0.991, 0.992]	0.078	0.679	0.574	INC	0.6	145474	0.752				
SBS40	SoftTissue-Liposarc	[3020, 3395, 3886, 4359, 4872, 5665, 6229, 6775, 8131, 3290]	[0.355, 0.4, 0.457, 0.514, 0.574, 0.669, 0.736, 0.803, 0.965, 1.0]	[0.962, 0.951, 0.978, 0.982, 0.979, 0.992, 0.979, 0.969, 0.964, 0.933]	0.074	0.645	0.566	INC	0.5	49719	0.752				
SBS40	Thy-AdenoCA	[174, 202, 230, 271, 309, 356, 417, 478, 583, 238]	[0.283, 0.329, 0.374, 0.441, 0.503, 0.581, 0.681, 0.783, 0.957, 1.0]	[0.76, 0.826, 0.853, 0.893, 0.905, 0.91, 0.908, 0.93, 0.96, 0.932]	0.083	0.717	0.628	INC	0.71	3265	0.755				
SBS40	ACROSS_ALL_CANCER_TYPES		[0.312, 0.332, 0.366, 0.418, 0.48, 0.56, 0.631, 0.73, 0.879, 1.0]	[0.88, 0.911, 0.929, 0.941, 0.946, 0.952, 0.954, 0.959, 0.967, 0.978]								31	0	0	31