# Only cancer types with minimum 2000 mutations for SBS signatures with average probability at least 0.75 are considered. signature cancer_type processive_group_length number_of_processive_groups log10_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_number_of_processive_groups SBS40 ALL 2 9 2.197 0.48 1.0 4.0 1.475 0.698 1.3925473489368743e-26 1.856729798582499e-26 25.731 [2, 1, 1, 2, 2, 2, 1, 1, 2, 1, 1, 1, 2, 1, 1, 2, 1, 1, 2, 3, 2, 1, 1, 1, 2, 1, 2, 2, 1, 3, 2, 2, 1, 1, 1, 2, 1, 2, 1, 1, 1, 1, 2, 1, 1, 3, 1, 1, 1, 1, 1, 1, 1, 4, 1, 1, 3, 1, 1] SBS40 Bladder-TCC 2 134 4.898 0.48 24.0 55.0 37.4 5.609 1.7124630488535402e-65 2.568694573280311e-65 64.59 [36, 37, 30, 37, 38, 34, 37, 44, 26, 29, 39, 41, 42, 40, 34, 46, 36, 46, 39, 33, 41, 35, 25, 48, 26, 36, 40, 34, 34, 29, 41, 37, 34, 44, 38, 37, 32, 39, 33, 38, 40, 34, 27, 34, 24, 37, 35, 45, 43, 43, 36, 37, 33, 37, 43, 45, 40, 39, 33, 34, 44, 43, 41, 37, 34, 31, 42, 39, 28, 40, 40, 46, 38, 30, 40, 32, 43, 32, 41, 39, 41, 33, 37, 39, 45, 45, 43, 46, 45, 41, 35, 32, 40, 36, 36, 34, 55, 31, 36, 26] SBS40 Bladder-TCC 3 3 1.099 0.108 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1] SBS40 Bone-Osteosarc 2 814 6.702 0.48 132.0 195.0 163.32 12.358 0.0 0.0 inf [148, 187, 151, 167, 163, 169, 155, 151, 156, 165, 171, 170, 144, 151, 171, 171, 153, 179, 154, 164, 165, 162, 171, 161, 168, 169, 191, 142, 160, 167, 169, 140, 147, 154, 167, 164, 166, 195, 167, 176, 172, 167, 135, 190, 165, 181, 158, 168, 170, 163, 146, 164, 173, 169, 171, 160, 164, 160, 178, 182, 167, 170, 189, 159, 164, 164, 160, 147, 154, 170, 149, 185, 154, 162, 159, 164, 137, 153, 157, 132, 150, 189, 166, 173, 160, 159, 156, 159, 159, 185, 142, 166, 166, 152, 152, 154, 166, 171, 172, 162] SBS40 Bone-Osteosarc 3 131 4.875 0.349 1.0 3.0 1.371 0.636 0.0 0.0 inf [1, 2, 1, 1, 2, 1, 3, 1, 1, 1, 1, 1, 1, 1, 1, 2, 1, 1, 1, 1, 1, 1, 1, 1, 2, 1, 1, 3, 1, 1, 1, 2, 2, 3, 2] SBS40 Bone-Osteosarc 4 43 3.761 0.269 inf [] SBS40 Bone-Osteosarc 5 22 3.091 0.221 inf [] SBS40 Bone-Osteosarc 6 11 2.398 0.172 inf [] SBS40 Bone-Osteosarc 7 3 1.099 0.079 inf [] SBS40 Bone-Osteosarc 8 4 1.386 0.099 inf [] SBS40 Bone-Osteosarc 9 7 1.946 0.139 inf [] SBS40 Bone-Osteosarc 13 1 0.0 0.0 inf [] SBS40 Bone-Osteosarc 14 1 0.0 0.0 inf [] SBS40 CNS-GBM 2 1035 6.942 0.48 230.0 317.0 266.78 16.859 0.0 0.0 inf [267, 287, 284, 269, 248, 258, 268, 282, 284, 280, 291, 279, 276, 280, 267, 258, 284, 281, 246, 258, 277, 243, 268, 252, 266, 243, 256, 277, 248, 282, 248, 242, 265, 240, 272, 247, 262, 294, 303, 272, 280, 259, 243, 275, 256, 274, 263, 264, 265, 269, 246, 239, 270, 247, 305, 251, 288, 253, 262, 230, 242, 269, 248, 283, 269, 280, 258, 276, 272, 267, 251, 243, 274, 286, 264, 267, 294, 289, 317, 240, 265, 267, 256, 282, 280, 240, 269, 263, 265, 250, 263, 240, 270, 288, 263, 278, 263, 304, 268, 272] SBS40 CNS-GBM 3 83 4.419 0.306 1.0 4.0 1.636 0.8 0.0 0.0 inf [3, 4, 1, 2, 3, 2, 1, 2, 1, 1, 3, 2, 2, 1, 1, 2, 2, 2, 1, 2, 1, 1, 1, 1, 1, 1, 2, 2, 2, 1, 1, 1, 2, 1, 1, 4, 2, 1, 1, 1, 1, 2, 1, 2] SBS40 CNS-GBM 4 21 3.045 0.211 1.0 1.0 1.0 0.0 inf [1] SBS40 CNS-GBM 5 12 2.485 0.172 inf [] SBS40 CNS-GBM 6 2 0.693 0.048 inf [] SBS40 CNS-GBM 7 1 0.0 0.0 inf [] SBS40 CNS-GBM 8 1 0.0 0.0 inf [] SBS40 CNS-Medullo 2 167 5.118 0.48 33.0 68.0 52.16 7.585 4.3018009505489273e-51 1.0037535551280829e-50 49.998 [64, 57, 57, 52, 59, 49, 51, 60, 50, 47, 53, 62, 49, 66, 65, 43, 59, 56, 43, 51, 43, 60, 48, 48, 67, 52, 60, 55, 57, 59, 49, 46, 52, 49, 40, 55, 56, 61, 50, 39, 55, 46, 54, 51, 57, 47, 52, 61, 48, 60, 48, 51, 46, 51, 54, 46, 58, 50, 55, 61, 46, 35, 55, 50, 57, 56, 58, 36, 57, 58, 48, 45, 60, 40, 52, 68, 46, 58, 60, 56, 33, 46, 43, 54, 50, 43, 45, 44, 42, 47, 53, 59, 51, 63, 62, 67, 40, 34, 55, 54] SBS40 CNS-Medullo 3 10 2.303 0.216 1.0 2.0 1.125 0.331 1.655626693248695e-140 1.1589386852740865e-139 138.936 [1, 1, 1, 1, 1, 1, 1, 1, 1, 2, 1, 1, 1, 2, 1, 1] SBS40 CNS-Medullo 4 1 0.0 0.0 inf [] SBS40 CNS-PiloAstro 2 12 2.485 0.48 1.0 2.0 1.077 0.266 0.0 0.0 inf [2, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1] SBS40 CNS-PiloAstro 3 1 0.0 0.0 inf [] SBS40 ColoRect-AdenoCA 2 2687 7.896 0.48 995.0 1159.0 1062.56 28.172 0.0 0.0 inf [1055, 1060, 1040, 1024, 1089, 1060, 1079, 1054, 1040, 1075, 1124, 1066, 1043, 1033, 1053, 1067, 1159, 1059, 1111, 1099, 1071, 1097, 1139, 1054, 1081, 1063, 1064, 1142, 1033, 1069, 1080, 1069, 1071, 1070, 1056, 1071, 1046, 1063, 1072, 1047, 1039, 1016, 1045, 1067, 1034, 1039, 1068, 1025, 1052, 1066, 1068, 1014, 1029, 1039, 1084, 1028, 1032, 1061, 1072, 1048, 1101, 1050, 1046, 1027, 1134, 1060, 1026, 1039, 1086, 1076, 1027, 1084, 1054, 1097, 1029, 1093, 1064, 1075, 1031, 1026, 1056, 1055, 1105, 1055, 1074, 1058, 1075, 1083, 1033, 1060, 995, 1081, 1066, 1068, 1063, 1068, 1079, 1032, 1070, 1081] SBS40 ColoRect-AdenoCA 3 154 5.037 0.306 1.0 12.0 5.515 2.409 0.0 0.0 inf [4, 7, 5, 3, 7, 3, 4, 7, 12, 8, 4, 6, 7, 9, 4, 10, 4, 5, 4, 1, 8, 6, 8, 5, 9, 7, 9, 4, 4, 4, 4, 5, 8, 4, 4, 2, 5, 10, 7, 6, 5, 7, 2, 7, 4, 6, 3, 6, 5, 3, 9, 8, 9, 8, 3, 5, 3, 7, 3, 10, 4, 6, 5, 6, 5, 3, 9, 4, 4, 6, 3, 4, 5, 7, 7, 7, 3, 1, 11, 5, 3, 4, 5, 4, 1, 2, 3, 4, 11, 9, 7, 9, 6, 4, 7, 2, 3, 6, 5] SBS40 ColoRect-AdenoCA 4 20 2.996 0.182 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1, 1, 1] SBS40 ColoRect-AdenoCA 5 11 2.398 0.146 inf [] SBS40 ColoRect-AdenoCA 6 3 1.099 0.067 inf [] SBS40 ColoRect-AdenoCA 7 3 1.099 0.067 inf [] SBS40 Ewings 2 15 2.708 0.48 1.0 3.0 1.343 0.583 4.003723151300177e-115 1.2011169453900533e-114 113.92 [1, 2, 1, 2, 1, 1, 1, 2, 2, 2, 1, 1, 1, 2, 3, 1, 1, 3, 1, 1, 1, 1, 2, 1, 1, 2, 1, 1, 1, 1, 1, 1, 1, 1, 1] SBS40 Head-SCC 2 658 6.489 0.48 215.0 301.0 263.45 16.599 9.382254158624539e-123 1.720079929081165e-122 121.764 [249, 250, 270, 242, 263, 284, 243, 263, 250, 272, 291, 254, 252, 215, 269, 267, 271, 299, 291, 264, 278, 295, 290, 271, 286, 276, 274, 261, 264, 269, 241, 266, 274, 260, 261, 248, 277, 251, 260, 251, 286, 239, 258, 252, 272, 264, 259, 266, 287, 267, 301, 298, 275, 273, 267, 271, 275, 240, 222, 270, 273, 258, 262, 265, 278, 248, 276, 277, 248, 277, 253, 260, 269, 270, 252, 228, 259, 257, 259, 265, 223, 250, 277, 251, 278, 241, 258, 265, 275, 257, 268, 249, 263, 246, 294, 239, 256, 246, 252, 269] SBS40 Head-SCC 3 14 2.639 0.195 1.0 4.0 1.662 0.797 8.20875667605968e-53 1.1287040429582059e-52 51.947 [1, 4, 2, 3, 2, 1, 2, 2, 1, 2, 4, 1, 2, 2, 1, 2, 3, 1, 1, 2, 2, 2, 2, 2, 2, 2, 1, 3, 1, 1, 2, 1, 3, 1, 2, 1, 2, 2, 1, 1, 1, 1, 1, 3, 1, 1, 1, 1, 1, 3, 1, 1, 1, 2, 1, 3, 1, 1, 2, 3, 2, 1, 1, 1, 1, 1, 1, 2] SBS40 Head-SCC 4 2 0.693 0.051 1.0 1.0 1.0 0.0 inf [1] SBS40 Head-SCC 5 2 0.693 0.051 inf [] SBS40 Head-SCC 6 1 0.0 0.0 inf [] SBS40 Head-SCC 8 1 0.0 0.0 inf [] SBS40 Head-SCC 10 1 0.0 0.0 inf [] SBS40 Kidney-RCC 2 5163 8.549 0.48 1540.0 1776.0 1637.17 44.205 0.0 0.0 inf [1575, 1648, 1649, 1619, 1566, 1673, 1631, 1553, 1585, 1599, 1650, 1575, 1586, 1625, 1637, 1591, 1625, 1646, 1642, 1665, 1638, 1656, 1646, 1681, 1650, 1617, 1599, 1618, 1650, 1667, 1703, 1568, 1636, 1638, 1569, 1570, 1604, 1650, 1657, 1652, 1630, 1673, 1685, 1653, 1703, 1608, 1632, 1662, 1595, 1693, 1660, 1631, 1604, 1611, 1642, 1690, 1679, 1636, 1653, 1663, 1568, 1624, 1776, 1656, 1680, 1634, 1603, 1691, 1686, 1639, 1649, 1585, 1710, 1614, 1740, 1594, 1573, 1605, 1590, 1659, 1616, 1679, 1602, 1664, 1619, 1632, 1600, 1666, 1604, 1707, 1549, 1646, 1593, 1659, 1657, 1719, 1678, 1745, 1654, 1540] SBS40 Kidney-RCC 3 133 4.89 0.275 1.0 13.0 4.102 2.354 0.0 0.0 inf [2, 1, 3, 2, 4, 1, 8, 9, 4, 1, 2, 2, 5, 6, 3, 8, 5, 2, 2, 3, 4, 2, 3, 9, 2, 6, 2, 2, 5, 2, 2, 2, 2, 5, 8, 5, 8, 3, 9, 4, 11, 2, 5, 4, 13, 5, 3, 2, 3, 3, 4, 5, 4, 6, 5, 2, 5, 2, 3, 4, 7, 2, 4, 2, 3, 4, 7, 4, 5, 1, 7, 3, 4, 7, 1, 4, 4, 6, 7, 1, 2, 4, 1, 5, 7, 3, 4, 2, 3, 6, 2, 7, 5, 2, 5, 6, 3, 3] SBS40 Kidney-RCC 4 32 3.466 0.195 inf [] SBS40 Kidney-RCC 5 13 2.565 0.144 inf [] SBS40 Kidney-RCC 6 3 1.099 0.062 inf [] SBS40 Kidney-RCC 7 1 0.0 0.0 inf [] SBS40 Kidney-RCC 8 2 0.693 0.039 inf [] SBS40 Kidney-RCC 9 1 0.0 0.0 inf [] SBS40 Kidney-RCC 10 2 0.693 0.039 inf [] SBS40 Kidney-RCC 12 1 0.0 0.0 inf [] SBS40 Kidney-RCC 15 1 0.0 0.0 inf [] SBS40 Lung-AdenoCA 2 2873 7.963 0.48 1466.0 1710.0 1586.26 42.542 2.5210213598822944e-197 5.942407491151124e-197 196.226 [1590, 1567, 1586, 1547, 1608, 1602, 1614, 1571, 1567, 1633, 1593, 1710, 1677, 1593, 1590, 1573, 1566, 1541, 1594, 1619, 1604, 1562, 1648, 1552, 1641, 1624, 1591, 1518, 1619, 1569, 1586, 1602, 1590, 1506, 1601, 1561, 1571, 1578, 1548, 1619, 1477, 1581, 1605, 1567, 1480, 1651, 1528, 1617, 1628, 1595, 1501, 1603, 1606, 1466, 1507, 1565, 1600, 1565, 1645, 1635, 1592, 1639, 1574, 1629, 1590, 1567, 1581, 1582, 1549, 1643, 1551, 1480, 1582, 1613, 1609, 1557, 1558, 1539, 1597, 1644, 1549, 1612, 1611, 1580, 1595, 1632, 1640, 1608, 1558, 1619, 1556, 1581, 1599, 1595, 1565, 1572, 1551, 1657, 1592, 1625] SBS40 Lung-AdenoCA 3 129 4.86 0.293 19.0 47.0 31.26 5.332 6.689997553722427e-74 1.1038495963642005e-73 72.957 [25, 36, 34, 35, 38, 32, 24, 26, 33, 30, 37, 36, 27, 21, 31, 34, 33, 38, 27, 26, 26, 25, 31, 24, 41, 32, 32, 26, 32, 31, 34, 32, 33, 35, 38, 35, 31, 28, 29, 31, 36, 29, 25, 31, 32, 31, 31, 33, 30, 32, 22, 35, 22, 32, 29, 36, 23, 23, 33, 30, 29, 33, 33, 33, 29, 27, 36, 26, 35, 32, 35, 34, 23, 29, 39, 42, 33, 34, 34, 34, 19, 30, 32, 35, 35, 26, 30, 28, 38, 30, 38, 22, 22, 32, 23, 47, 39, 37, 23, 46] SBS40 Lung-AdenoCA 4 20 2.996 0.181 1.0 4.0 1.491 0.806 7.441348346877009e-113 1.4444970320408312e-112 111.84 [1, 1, 1, 3, 1, 1, 2, 1, 2, 1, 1, 1, 1, 2, 1, 1, 1, 1, 2, 1, 1, 2, 1, 1, 1, 1, 1, 3, 1, 2, 3, 3, 1, 1, 2, 1, 3, 2, 1, 4, 1, 2, 1, 1, 2, 1, 1, 4, 1, 2, 1, 1, 1, 1, 1] SBS40 Lung-AdenoCA 5 4 1.386 0.084 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1, 1, 1] SBS40 Lung-AdenoCA 6 2 0.693 0.042 inf [] SBS40 Lung-AdenoCA 7 2 0.693 0.042 inf [] SBS40 Lung-AdenoCA 8 1 0.0 0.0 inf [] SBS40 Panc-AdenoCA 2 2433 7.797 0.48 520.0 622.0 567.65 22.415 0.0 0.0 inf [552, 547, 562, 583, 527, 583, 585, 596, 587, 583, 551, 562, 579, 545, 567, 545, 583, 567, 532, 563, 570, 545, 571, 571, 544, 589, 599, 595, 585, 574, 537, 582, 529, 533, 559, 531, 592, 531, 560, 550, 578, 576, 578, 529, 576, 586, 554, 559, 576, 577, 542, 563, 602, 610, 550, 587, 553, 569, 553, 540, 610, 569, 585, 580, 570, 607, 556, 568, 524, 572, 572, 547, 546, 552, 583, 564, 591, 575, 610, 576, 571, 592, 520, 596, 561, 601, 553, 570, 578, 560, 527, 558, 541, 622, 549, 570, 572, 567, 618, 578] SBS40 Panc-AdenoCA 3 250 5.521 0.34 1.0 5.0 1.87 1.034 0.0 0.0 inf [4, 3, 1, 1, 1, 1, 1, 2, 1, 3, 3, 3, 1, 1, 2, 4, 3, 1, 2, 4, 2, 2, 1, 2, 3, 1, 2, 1, 2, 3, 2, 2, 2, 3, 1, 1, 1, 3, 1, 1, 3, 2, 1, 1, 2, 5, 1, 2, 2, 5, 2, 1, 1, 2, 1, 1, 2, 3, 1, 1, 1, 1, 1, 2, 1, 3, 1, 1, 1] SBS40 Panc-AdenoCA 4 76 4.331 0.267 inf [] SBS40 Panc-AdenoCA 5 45 3.807 0.234 inf [] SBS40 Panc-AdenoCA 6 21 3.045 0.187 inf [] SBS40 Panc-AdenoCA 7 7 1.946 0.12 inf [] SBS40 Panc-AdenoCA 8 2 0.693 0.043 inf [] SBS40 Panc-AdenoCA 9 5 1.609 0.099 inf [] SBS40 Panc-AdenoCA 10 2 0.693 0.043 inf [] SBS40 Panc-AdenoCA 11 1 0.0 0.0 inf [] SBS40 Panc-AdenoCA 16 1 0.0 0.0 inf [] SBS40 Prost-AdenoCA 2 2005 7.603 0.48 233.0 318.0 263.92 16.461 0.0 0.0 inf [265, 284, 257, 267, 264, 243, 261, 245, 302, 272, 267, 278, 301, 274, 245, 236, 265, 251, 254, 238, 234, 275, 266, 253, 256, 268, 266, 253, 259, 240, 269, 274, 241, 300, 280, 272, 318, 291, 276, 264, 266, 253, 263, 245, 252, 266, 253, 254, 242, 270, 261, 271, 256, 277, 253, 271, 261, 233, 250, 254, 285, 241, 234, 275, 267, 270, 277, 278, 278, 252, 246, 257, 248, 276, 261, 282, 293, 255, 269, 277, 282, 252, 264, 270, 253, 248, 266, 261, 264, 252, 254, 247, 280, 274, 279, 310, 251, 264, 272, 253] SBS40 Prost-AdenoCA 3 361 5.889 0.372 1.0 3.0 1.273 0.509 0.0 0.0 inf [1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 1, 1, 1, 1, 2, 2, 1, 1, 1, 2, 2, 2, 3, 1, 1, 1, 1, 1, 1, 1] SBS40 Prost-AdenoCA 4 184 5.215 0.329 inf [] SBS40 Prost-AdenoCA 5 72 4.277 0.27 inf [] SBS40 Prost-AdenoCA 6 16 2.773 0.175 inf [] SBS40 Prost-AdenoCA 7 31 3.434 0.217 inf [] SBS40 Prost-AdenoCA 8 8 2.079 0.131 inf [] SBS40 Prost-AdenoCA 9 8 2.079 0.131 inf [] SBS40 Prost-AdenoCA 10 1 0.0 0.0 inf [] SBS40 Prost-AdenoCA 11 6 1.792 0.113 inf [] SBS40 SoftTissue-Leiomyo 2 580 6.363 0.48 111.0 186.0 150.94 12.277 1.2993828967653523e-262 1.9490743451480287e-262 261.71 [169, 168, 153, 143, 186, 145, 147, 157, 151, 143, 131, 152, 153, 161, 162, 139, 146, 122, 159, 139, 159, 169, 135, 151, 142, 149, 137, 160, 154, 172, 111, 162, 164, 145, 136, 143, 149, 167, 136, 159, 161, 131, 143, 142, 151, 166, 145, 150, 162, 170, 162, 144, 138, 164, 153, 153, 139, 155, 172, 153, 141, 154, 131, 147, 155, 152, 153, 155, 163, 154, 147, 153, 135, 158, 150, 153, 127, 162, 161, 134, 165, 141, 149, 144, 156, 146, 162, 157, 161, 132, 156, 127, 154, 166, 141, 147, 165, 146, 152, 162] SBS40 SoftTissue-Leiomyo 3 57 4.043 0.305 1.0 4.0 1.316 0.653 0.0 0.0 inf [1, 2, 1, 1, 1, 1, 1, 1, 4, 1, 2, 1, 1, 1, 1, 2, 1, 2, 2, 1, 1, 1, 1, 1, 1, 1, 3, 1, 1, 2, 2, 1, 1, 1, 1, 1, 1, 1] SBS40 SoftTissue-Leiomyo 4 30 3.401 0.257 inf [] SBS40 SoftTissue-Leiomyo 5 11 2.398 0.181 inf [] SBS40 SoftTissue-Leiomyo 6 8 2.079 0.157 inf [] SBS40 SoftTissue-Leiomyo 7 3 1.099 0.083 inf [] SBS40 SoftTissue-Leiomyo 8 1 0.0 0.0 inf [] SBS40 SoftTissue-Leiomyo 9 4 1.386 0.105 inf [] SBS40 SoftTissue-Leiomyo 12 1 0.0 0.0 inf [] SBS40 Stomach-AdenoCA 2 543 6.297 0.48 187.0 260.0 225.46 14.031 1.7139276782876877e-111 4.362724999277751e-111 110.36 [242, 187, 226, 222, 228, 243, 234, 248, 190, 222, 247, 209, 247, 240, 209, 231, 219, 223, 235, 236, 221, 217, 249, 226, 227, 227, 215, 211, 245, 225, 241, 218, 216, 231, 237, 221, 224, 220, 234, 218, 230, 227, 207, 207, 221, 252, 224, 212, 241, 214, 217, 249, 218, 241, 217, 208, 241, 229, 229, 214, 218, 232, 228, 229, 260, 201, 221, 234, 209, 208, 225, 240, 229, 218, 220, 207, 231, 204, 233, 248, 213, 240, 202, 234, 230, 214, 234, 252, 220, 201, 207, 240, 234, 221, 238, 209, 217, 229, 225, 232] SBS40 Stomach-AdenoCA 3 41 3.714 0.283 1.0 5.0 1.805 1.027 0.0 0.0 inf [1, 1, 1, 2, 1, 3, 2, 2, 1, 2, 1, 1, 1, 1, 2, 1, 1, 1, 3, 5, 1, 1, 1, 1, 2, 1, 4, 3, 3, 2, 3, 2, 1, 1, 3, 3, 3, 1, 3, 1, 1, 3, 1, 2, 1, 1, 2, 1, 1, 3, 1, 2, 1, 5, 3, 3, 1, 2, 1, 2, 2, 4, 2, 1, 1, 1, 1, 4, 2, 3, 2, 1, 2, 1, 3, 1, 1, 2, 1, 4, 1, 1, 1, 1, 2, 1, 1] SBS40 Stomach-AdenoCA 4 10 2.303 0.176 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1, 1] SBS40 Stomach-AdenoCA 5 5 1.609 0.123 inf [] SBS40 Stomach-AdenoCA 6 1 0.0 0.0 inf [] SBS40 Stomach-AdenoCA 7 1 0.0 0.0 inf [] SBS40 Stomach-AdenoCA 9 1 0.0 0.0 inf [] SBS40 Stomach-AdenoCA 14 1 0.0 0.0 inf [] SBS40 Uterus-AdenoCA 2 1010 6.918 0.48 338.0 448.0 389.52 18.828 8.629134693123546e-234 3.9310502490896157e-233 232.405 [397, 389, 402, 379, 355, 422, 406, 364, 380, 385, 377, 388, 413, 388, 378, 377, 404, 409, 399, 416, 412, 380, 405, 372, 406, 402, 397, 363, 382, 412, 358, 379, 372, 395, 406, 380, 372, 409, 416, 387, 380, 372, 380, 395, 406, 388, 376, 358, 417, 338, 398, 395, 379, 387, 367, 395, 404, 403, 389, 392, 396, 384, 393, 385, 448, 393, 379, 357, 376, 405, 395, 410, 386, 358, 365, 410, 378, 416, 365, 372, 374, 418, 395, 386, 404, 413, 411, 384, 383, 373, 371, 359, 412, 357, 407, 372, 386, 403, 398, 423] SBS40 Uterus-AdenoCA 3 45 3.807 0.264 1.0 5.0 1.782 0.929 0.0 0.0 inf [1, 1, 2, 2, 2, 4, 1, 2, 1, 1, 2, 3, 1, 1, 1, 2, 1, 2, 1, 1, 1, 3, 1, 3, 3, 1, 2, 1, 2, 2, 1, 2, 2, 1, 1, 2, 2, 4, 1, 1, 1, 2, 1, 1, 1, 1, 1, 1, 5, 2, 1, 3, 2, 2, 3, 3, 3, 1, 1, 1, 2, 2, 1, 4, 2, 1, 3, 1, 1, 3, 1, 2, 3, 2, 1, 3, 1, 2] SBS40 Uterus-AdenoCA 4 10 2.303 0.16 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1] SBS40 Uterus-AdenoCA 5 4 1.386 0.096 inf [] SBS40 Uterus-AdenoCA 6 2 0.693 0.048 inf [] SBS40 Uterus-AdenoCA 8 1 0.0 0.0 inf [] SBS40 Biliary-AdenoCA 2 1052 3.022 0.48 184.0 257.0 208.58 13.777 0.0 0.0 inf [201, 225, 201, 209, 215, 231, 223, 202, 209, 192, 185, 226, 184, 194, 193, 214, 184, 209, 205, 196, 210, 229, 195, 232, 215, 232, 224, 208, 201, 208, 192, 187, 196, 222, 186, 206, 213, 200, 236, 227, 212, 210, 211, 214, 210, 202, 210, 205, 194, 203, 214, 222, 184, 201, 204, 225, 228, 199, 206, 215, 202, 212, 196, 213, 218, 257, 201, 200, 225, 198, 228, 198, 216, 207, 202, 201, 199, 211, 213, 211, 223, 191, 211, 214, 234, 199, 234, 218, 189, 184, 189, 223, 209, 198, 205, 218, 216, 205, 206, 198] SBS40 Biliary-AdenoCA 3 37 1.568 0.249 1.0 3.0 1.34 0.552 0.0 0.0 inf [1, 1, 1, 3, 1, 1, 2, 1, 1, 2, 1, 2, 1, 1, 2, 1, 1, 2, 1, 2, 1, 2, 1, 1, 2, 1, 1, 1, 2, 3, 1, 2, 1, 1, 2, 1, 1, 1, 1, 1, 1, 2, 2, 1, 1, 1, 1, 1, 1, 1] SBS40 Biliary-AdenoCA 4 7 0.845 0.134 inf [] SBS40 Biliary-AdenoCA 5 3 0.477 0.076 inf [] SBS40 Biliary-AdenoCA 7 1 0.0 0.0 inf [] SBS40 Bone-Epith 2 64 4.159 0.48 2.0 14.0 5.74 2.44 7.1594522638463615e-124 7.1594522638463615e-124 123.145 [4, 7, 5, 4, 5, 7, 5, 8, 8, 8, 3, 3, 4, 5, 7, 6, 5, 2, 14, 3, 2, 3, 8, 5, 5, 2, 6, 10, 7, 5, 5, 2, 8, 3, 4, 5, 7, 8, 3, 7, 4, 5, 8, 4, 7, 3, 4, 3, 10, 2, 5, 8, 6, 8, 7, 6, 9, 7, 4, 12, 8, 9, 5, 10, 7, 9, 9, 4, 3, 6, 8, 5, 4, 8, 5, 5, 2, 7, 5, 2, 6, 2, 4, 8, 4, 7, 5, 11, 4, 4, 6, 4, 3, 5, 8, 6, 5, 5, 5, 11] SBS40 Bone-Epith 3 4 1.386 0.16 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1] SBS40 Breast-Cancer 2 35 3.555 0.48 1.0 16.0 9.07 3.031 1.2199849701637451e-17 1.8808101623357735e-17 16.726 [9, 7, 9, 4, 8, 13, 7, 8, 10, 3, 12, 9, 7, 15, 6, 12, 9, 10, 16, 10, 9, 14, 7, 8, 7, 7, 11, 8, 6, 14, 10, 10, 2, 8, 6, 8, 15, 6, 8, 11, 10, 11, 8, 12, 12, 7, 10, 7, 11, 8, 8, 12, 14, 9, 6, 10, 11, 13, 7, 6, 11, 12, 8, 9, 13, 10, 12, 7, 1, 9, 7, 13, 12, 1, 10, 12, 10, 6, 8, 9, 10, 6, 10, 7, 10, 8, 6, 5, 9, 8, 12, 16, 10, 11, 4, 10, 10, 3, 8, 13] SBS40 Breast-Cancer 3 3 1.099 0.148 1.0 1.0 1.0 0.0 inf [1] SBS40 Cervix-Cancer 2 18 2.89 0.48 1.0 8.0 2.585 1.417 2.6238237314457607e-27 2.9986556930808692e-27 26.523 [3, 1, 5, 3, 3, 3, 3, 4, 5, 1, 2, 4, 1, 2, 4, 2, 4, 2, 1, 4, 2, 8, 4, 2, 3, 1, 1, 2, 2, 1, 4, 2, 3, 2, 2, 5, 2, 2, 3, 3, 5, 1, 3, 2, 3, 5, 4, 1, 2, 3, 2, 5, 2, 4, 3, 1, 4, 4, 2, 2, 2, 1, 1, 3, 2, 2, 4, 2, 5, 5, 1, 1, 6, 2, 3, 2, 2, 1, 1, 4, 3, 1, 4, 1, 3, 1, 2, 1, 1, 2, 1, 2, 1, 1] SBS40 Eso-AdenoCA 2 5458 8.605 0.48 2537.0 2792.0 2680.02 53.372 0.0 0.0 inf [2537, 2680, 2713, 2680, 2724, 2616, 2621, 2697, 2726, 2654, 2578, 2649, 2777, 2634, 2736, 2711, 2738, 2759, 2725, 2684, 2704, 2666, 2703, 2686, 2633, 2700, 2676, 2682, 2718, 2736, 2590, 2633, 2679, 2680, 2680, 2737, 2739, 2607, 2757, 2792, 2726, 2659, 2730, 2680, 2752, 2612, 2592, 2586, 2650, 2732, 2670, 2748, 2666, 2638, 2631, 2717, 2653, 2706, 2633, 2707, 2687, 2632, 2725, 2584, 2612, 2757, 2646, 2672, 2697, 2703, 2554, 2661, 2729, 2644, 2686, 2649, 2733, 2702, 2730, 2706, 2702, 2789, 2692, 2638, 2728, 2627, 2574, 2606, 2737, 2659, 2721, 2717, 2715, 2683, 2681, 2693, 2608, 2641, 2743, 2614] SBS40 Eso-AdenoCA 3 277 5.624 0.314 9.0 27.0 17.3 4.48 0.0 0.0 inf [20, 10, 17, 24, 18, 24, 15, 16, 24, 19, 20, 10, 17, 19, 22, 15, 14, 20, 19, 12, 15, 16, 17, 18, 23, 22, 21, 12, 23, 14, 16, 10, 15, 18, 24, 9, 21, 16, 26, 23, 14, 17, 23, 14, 25, 27, 15, 16, 9, 16, 21, 13, 10, 23, 18, 17, 24, 13, 10, 27, 16, 14, 23, 17, 13, 11, 22, 19, 17, 12, 18, 14, 18, 18, 18, 11, 15, 15, 16, 14, 15, 21, 14, 15, 18, 10, 15, 16, 23, 11, 25, 21, 17, 20, 18, 17, 12, 20, 24, 11] SBS40 Eso-AdenoCA 4 56 4.025 0.225 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1] SBS40 Eso-AdenoCA 5 23 3.135 0.175 inf [] SBS40 Eso-AdenoCA 6 13 2.565 0.143 inf [] SBS40 Eso-AdenoCA 7 9 2.197 0.123 inf [] SBS40 Eso-AdenoCA 8 4 1.386 0.077 inf [] SBS40 Eso-AdenoCA 9 2 0.693 0.039 inf [] SBS40 Eso-AdenoCA 10 3 1.099 0.061 inf [] SBS40 Eso-AdenoCA 11 1 0.0 0.0 inf [] SBS40 Eso-AdenoCA 13 1 0.0 0.0 inf [] SBS40 ESCC 2 1993 7.597 0.48 899.0 1047.0 972.18 29.151 1.1093974259486398e-263 4.9922884167688795e-263 262.302 [972, 973, 1002, 996, 973, 964, 954, 989, 999, 1047, 968, 1004, 1006, 968, 938, 953, 969, 992, 964, 942, 923, 957, 1036, 934, 967, 944, 996, 942, 989, 991, 1002, 954, 962, 1009, 994, 1037, 980, 953, 942, 987, 955, 935, 970, 962, 974, 983, 917, 932, 979, 958, 905, 985, 965, 984, 1024, 955, 937, 983, 929, 969, 946, 960, 964, 986, 997, 973, 970, 1013, 921, 965, 1029, 962, 980, 1000, 975, 963, 1010, 927, 899, 987, 937, 986, 953, 947, 967, 932, 944, 1003, 960, 1037, 983, 1000, 959, 1005, 999, 970, 1000, 990, 975, 971] SBS40 ESCC 3 71 4.263 0.269 2.0 10.0 5.18 1.889 3.927814833955491e-261 1.4729305627333091e-260 259.832 [2, 5, 5, 4, 3, 4, 7, 5, 3, 5, 4, 4, 6, 2, 4, 4, 4, 6, 5, 8, 8, 6, 4, 6, 3, 5, 3, 7, 5, 6, 7, 9, 4, 2, 6, 9, 4, 7, 7, 6, 9, 5, 5, 5, 6, 2, 4, 6, 5, 5, 7, 3, 6, 8, 3, 4, 3, 8, 7, 5, 4, 5, 4, 7, 2, 3, 2, 6, 5, 8, 6, 6, 10, 4, 5, 3, 4, 8, 7, 3, 3, 8, 5, 5, 9, 3, 4, 5, 4, 6, 4, 6, 7, 4, 9, 8, 5, 4, 4, 3] SBS40 ESCC 4 18 2.89 0.183 1.0 1.0 1.0 0.0 3.927814833955491e-261 1.4729305627333091e-260 259.832 [1, 1, 1, 1, 1] SBS40 ESCC 5 4 1.386 0.088 inf [] SBS40 ESCC 8 1 0.0 0.0 inf [] SBS40 ESCC 9 1 0.0 0.0 inf [] SBS40 Kidney-ChRCC 2 202 5.308 0.48 24.0 57.0 37.35 6.561 1.4524757852653752e-136 2.9049515705307504e-136 135.537 [33, 41, 40, 33, 37, 31, 39, 37, 29, 48, 35, 27, 31, 37, 43, 31, 32, 42, 35, 32, 48, 34, 35, 37, 37, 51, 29, 47, 34, 38, 35, 42, 42, 24, 40, 26, 29, 34, 47, 52, 36, 38, 41, 33, 33, 32, 31, 33, 57, 44, 33, 28, 32, 41, 27, 37, 45, 31, 41, 29, 48, 41, 41, 37, 28, 45, 41, 40, 40, 30, 40, 34, 44, 38, 32, 50, 30, 36, 33, 38, 28, 40, 32, 31, 36, 40, 54, 39, 42, 38, 43, 40, 39, 37, 41, 34, 40, 36, 51, 32] SBS40 Kidney-ChRCC 3 11 2.398 0.217 1.0 1.0 1.0 0.0 0.0 0.0 inf [1, 1, 1, 1, 1] SBS40 Kidney-ChRCC 4 5 1.609 0.146 inf [] SBS40 Kidney-ChRCC 6 1 0.0 0.0 inf [] SBS40 Kidney-ChRCC 7 2 0.693 0.063 inf [] SBS40 Kidney-ChRCC 11 1 0.0 0.0 inf [] SBS40 Kidney-ChRCC 14 1 0.0 0.0 inf [] SBS40 Liver-HCC 2 1945 7.573 0.48 373.0 468.0 416.27 20.722 0.0 0.0 inf [380, 427, 392, 422, 426, 405, 412, 415, 449, 421, 412, 375, 397, 373, 418, 378, 433, 381, 459, 428, 436, 438, 410, 427, 425, 377, 417, 411, 465, 436, 387, 432, 415, 426, 432, 430, 425, 419, 412, 404, 435, 444, 384, 410, 381, 399, 392, 406, 387, 411, 432, 438, 401, 408, 435, 440, 414, 466, 399, 390, 431, 468, 391, 416, 436, 444, 402, 394, 416, 423, 415, 402, 407, 414, 417, 433, 388, 422, 397, 425, 404, 438, 410, 421, 440, 400, 421, 417, 398, 437, 430, 418, 418, 429, 400, 408, 399, 459, 411, 429] SBS40 Liver-HCC 3 52 3.951 0.25 1.0 6.0 2.422 1.273 0.0 0.0 inf [1, 2, 1, 2, 2, 3, 3, 5, 2, 1, 1, 3, 5, 2, 2, 2, 3, 1, 3, 5, 4, 3, 3, 3, 1, 3, 3, 1, 2, 3, 3, 1, 3, 2, 4, 2, 4, 2, 3, 2, 3, 2, 1, 1, 2, 4, 4, 3, 1, 5, 1, 3, 2, 2, 1, 4, 3, 1, 1, 2, 1, 3, 2, 2, 5, 1, 4, 1, 1, 1, 1, 2, 3, 1, 4, 1, 1, 3, 1, 3, 5, 1, 2, 3, 2, 2, 3, 6, 1, 5] SBS40 Liver-HCC 4 9 2.197 0.139 inf [] SBS40 Liver-HCC 5 1 0.0 0.0 inf [] SBS40 Liver-HCC 6 1 0.0 0.0 inf [] SBS40 Liver-HCC 8 1 0.0 0.0 inf [] SBS40 Lymph-BNHL 2 1409 3.149 0.48 788.0 910.0 851.65 25.902 5.252901062105359e-101 3.501934041403572e-100 99.456 [813, 902, 887, 827, 868, 869, 825, 893, 851, 849, 824, 816, 836, 878, 850, 850, 858, 875, 830, 805, 811, 855, 872, 869, 896, 806, 795, 874, 866, 841, 824, 852, 858, 816, 881, 850, 876, 835, 852, 863, 847, 850, 846, 887, 874, 833, 900, 891, 871, 848, 854, 837, 852, 867, 875, 842, 825, 857, 847, 865, 851, 889, 850, 838, 870, 826, 883, 880, 869, 788, 847, 894, 833, 798, 851, 878, 819, 858, 822, 868, 815, 854, 910, 873, 837, 899, 862, 841, 833, 841, 821, 847, 865, 861, 845, 809, 866, 838, 830, 840] SBS40 Lymph-BNHL 3 20 1.301 0.198 1.0 11.0 5.26 2.105 2.080200547223516e-12 2.9717150674621654e-12 11.527 [8, 8, 3, 10, 7, 2, 2, 7, 6, 7, 6, 5, 5, 7, 3, 2, 7, 6, 4, 6, 8, 5, 4, 5, 3, 4, 7, 7, 5, 8, 3, 8, 4, 2, 9, 7, 8, 4, 7, 6, 5, 4, 11, 4, 4, 3, 6, 3, 2, 4, 10, 3, 3, 6, 3, 3, 5, 5, 4, 3, 5, 2, 3, 6, 6, 5, 9, 5, 6, 9, 7, 2, 1, 10, 6, 6, 6, 8, 6, 5, 3, 5, 6, 6, 5, 5, 2, 5, 6, 3, 7, 5, 7, 4, 7, 4, 5, 4, 4, 4] SBS40 Lymph-BNHL 4 1 0.0 0.0 1.0 1.0 1.0 0.0 inf [1, 1, 1, 1, 1] SBS40 Lymph-CLL 2 2 0.301 0.48 1.0 4.0 1.857 0.833 0.4327859980905814 0.8345366488286836 0.079 [1, 2, 2, 1, 1, 3, 1, 2, 2, 3, 1, 3, 2, 2, 3, 3, 1, 1, 1, 1, 1, 3, 1, 2, 3, 1, 1, 2, 2, 3, 2, 1, 3, 1, 2, 1, 2, 2, 2, 1, 2, 1, 1, 3, 2, 1, 2, 2, 1, 3, 2, 4, 2, 3, 2, 1, 2, 1, 3, 2, 1, 1, 1, 1, 3, 1, 2, 1, 2, 2, 1, 2, 3, 2, 3, 4, 1] SBS40 Ovary-AdenoCA 2 786 6.667 0.48 229.0 327.0 273.47 17.584 2.074027686327798e-183 3.2838771700190146e-183 182.484 [268, 292, 283, 286, 261, 281, 314, 263, 276, 258, 284, 265, 300, 274, 297, 273, 270, 292, 269, 286, 246, 267, 280, 307, 270, 265, 280, 274, 229, 286, 287, 299, 288, 253, 263, 269, 271, 284, 250, 255, 278, 258, 253, 305, 273, 286, 267, 236, 277, 275, 327, 286, 289, 237, 274, 316, 259, 265, 265, 254, 270, 262, 287, 252, 289, 286, 262, 264, 275, 264, 269, 252, 289, 259, 294, 296, 248, 284, 298, 271, 282, 264, 274, 276, 248, 278, 286, 247, 297, 269, 260, 266, 242, 263, 280, 262, 257, 278, 281, 271] SBS40 Ovary-AdenoCA 3 53 3.97 0.286 1.0 5.0 1.613 0.849 0.0 0.0 inf [1, 2, 1, 1, 1, 1, 1, 3, 3, 1, 1, 1, 2, 3, 1, 2, 1, 1, 2, 1, 4, 1, 2, 1, 1, 1, 1, 1, 3, 1, 2, 1, 1, 2, 3, 1, 2, 1, 2, 2, 5, 2, 2, 2, 1, 1, 1, 1, 3, 1, 2, 1, 1, 1, 1, 2, 2, 1, 2, 2, 2, 1] SBS40 Ovary-AdenoCA 4 11 2.398 0.173 1.0 1.0 1.0 0.0 inf [1] SBS40 Ovary-AdenoCA 5 8 2.079 0.15 inf [] SBS40 Ovary-AdenoCA 6 4 1.386 0.1 inf [] SBS40 Ovary-AdenoCA 7 2 0.693 0.05 inf [] SBS40 Ovary-AdenoCA 9 2 0.693 0.05 inf [] SBS40 Ovary-AdenoCA 11 1 0.0 0.0 inf [] SBS40 Panc-Endocrine 2 84 4.431 0.48 10.0 34.0 20.89 4.574 8.628488170910241e-43 3.106255741527686e-42 41.508 [23, 19, 29, 27, 18, 26, 20, 18, 22, 20, 33, 21, 21, 20, 21, 17, 20, 27, 17, 22, 16, 22, 22, 16, 22, 23, 15, 26, 19, 22, 15, 21, 18, 16, 20, 25, 17, 24, 19, 23, 30, 20, 21, 14, 18, 20, 15, 26, 19, 22, 28, 24, 16, 20, 20, 20, 21, 12, 23, 23, 23, 17, 16, 21, 18, 23, 22, 23, 27, 31, 18, 29, 19, 20, 20, 20, 19, 16, 19, 12, 12, 34, 21, 22, 17, 22, 29, 17, 25, 19, 26, 19, 22, 22, 22, 15, 10, 28, 27, 13] SBS40 Panc-Endocrine 3 3 1.099 0.119 1.0 2.0 1.167 0.373 1.607977781600339e-05 2.411966672400509e-05 4.618 [1, 1, 1, 1, 2, 1] SBS40 Panc-Endocrine 8 1 0.0 0.0 inf [] SBS40 Skin-Melanoma 2 1773 3.249 0.48 284.0 371.0 328.33 18.593 0.0 0.0 inf [335, 355, 297, 327, 333, 328, 347, 344, 324, 311, 329, 349, 352, 301, 324, 335, 331, 287, 344, 334, 323, 326, 311, 355, 355, 348, 335, 347, 365, 348, 325, 331, 339, 340, 340, 308, 328, 345, 317, 323, 307, 334, 329, 326, 336, 344, 318, 297, 314, 306, 306, 312, 314, 343, 345, 336, 339, 327, 324, 321, 354, 308, 314, 369, 328, 306, 313, 302, 341, 333, 335, 325, 333, 312, 334, 310, 337, 332, 327, 285, 310, 303, 301, 329, 324, 344, 284, 342, 347, 349, 359, 302, 371, 336, 326, 288, 322, 324, 349, 351] SBS40 Skin-Melanoma 3 292 2.465 0.364 1.0 5.0 1.652 0.929 0.0 0.0 inf [2, 1, 1, 1, 1, 2, 1, 5, 1, 2, 1, 1, 2, 1, 1, 2, 2, 1, 2, 1, 2, 1, 2, 3, 2, 2, 2, 3, 1, 1, 1, 1, 4, 1, 2, 1, 1, 2, 1, 1, 2, 1, 1, 1, 2, 1, 1, 2, 1, 1, 1, 2, 1, 1, 4, 2, 1, 1, 2, 4, 4, 1, 2, 3, 1, 1] SBS40 Skin-Melanoma 4 111 2.045 0.302 1.0 1.0 1.0 0.0 inf [1] SBS40 Skin-Melanoma 5 43 1.633 0.241 inf [] SBS40 Skin-Melanoma 6 22 1.342 0.198 inf [] SBS40 Skin-Melanoma 7 10 1.0 0.148 inf [] SBS40 Skin-Melanoma 8 8 0.903 0.133 inf [] SBS40 Skin-Melanoma 9 4 0.602 0.089 inf [] SBS40 Skin-Melanoma 10 1 0.0 0.0 inf [] SBS40 Skin-Melanoma 11 1 0.0 0.0 inf [] SBS40 Skin-Melanoma 13 1 0.0 0.0 inf [] SBS40 SoftTissue-Liposarc 2 733 6.597 0.48 62.0 111.0 81.76 9.393 0.0 0.0 inf [80, 81, 84, 88, 77, 80, 76, 71, 74, 73, 100, 98, 76, 87, 81, 77, 75, 68, 92, 83, 79, 88, 81, 77, 90, 62, 77, 92, 80, 64, 93, 90, 76, 78, 95, 87, 87, 86, 80, 88, 90, 77, 80, 97, 75, 73, 70, 92, 72, 73, 93, 89, 74, 85, 89, 76, 86, 98, 67, 80, 80, 90, 77, 66, 62, 89, 80, 86, 68, 80, 87, 78, 87, 77, 80, 90, 76, 76, 83, 97, 104, 67, 111, 74, 78, 75, 82, 82, 87, 83, 107, 74, 73, 87, 86, 79, 74, 88, 71, 78] SBS40 SoftTissue-Liposarc 3 151 5.017 0.365 1.0 2.0 1.227 0.419 0.0 0.0 inf [1, 1, 1, 1, 1, 1, 1, 2, 1, 2, 1, 1, 1, 2, 1, 1, 1, 1, 2, 2, 1, 1] SBS40 SoftTissue-Liposarc 4 47 3.85 0.28 inf [] SBS40 SoftTissue-Liposarc 5 14 2.639 0.192 inf [] SBS40 SoftTissue-Liposarc 6 8 2.079 0.151 inf [] SBS40 SoftTissue-Liposarc 7 3 1.099 0.08 inf [] SBS40 SoftTissue-Liposarc 8 2 0.693 0.05 inf [] SBS40 SoftTissue-Liposarc 9 2 0.693 0.05 inf [] SBS40 SoftTissue-Liposarc 10 1 0.0 0.0 inf [] SBS40 SoftTissue-Liposarc 11 5 1.609 0.117 inf [] SBS40 SoftTissue-Liposarc 13 1 0.0 0.0 inf [] SBS40 SoftTissue-Liposarc 21 1 0.0 0.0 inf [] SBS40 Thy-AdenoCA 2 9 2.197 0.48 1.0 3.0 1.264 0.519 1.1519749892952987e-48 1.3823699871543582e-48 47.859 [1, 1, 1, 1, 1, 1, 1, 1, 1, 3, 1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 2, 2, 1, 1, 1, 1, 1, 2, 2, 1, 1, 1, 1, 1, 2, 1, 1, 1, 2, 1, 1, 1, 1, 1, 1, 1, 3, 1, 1, 1, 1, 2, 2] signature cancer_type processive_group_length avg_number_of_processive_groups log10_avg_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_avg_number_of_processive_groups SBS40 ACROSS_ALL_CANCER_TYPES 10 1.571 0.196 0.031 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 11 2.286 0.359 0.056 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 12 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 13 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 14 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 15 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 16 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 2 1151.645 3.061 0.48 395.935 413.906 405.21 3.397 0.0 0.0 inf [395.935, 409.194, 407.097, 402.065, 404.774, 407.323, 405.226, 404.645, 405.097, 406.452, 405.0, 406.419, 411.645, 400.196, 405.615, 400.357, 409.777, 407.486, 408.938, 405.873, 404.164, 406.809, 413.906, 406.486, 409.454, 404.486, 405.067, 405.164, 408.97, 410.744, 400.293, 401.486, 402.712, 401.519, 405.551, 403.207, 408.53, 405.143, 407.917, 410.078, 404.368, 400.691, 403.659, 405.175, 404.885, 405.336, 396.304, 398.788, 405.626, 407.014, 402.239, 408.465, 401.659, 400.893, 405.151, 408.28, 405.603, 405.377, 402.183, 405.037, 406.521, 405.65, 407.844, 404.263, 412.715, 409.554, 401.36, 405.554, 404.037, 406.554, 399.908, 399.876, 408.134, 401.973, 407.779, 404.424, 402.36, 403.388, 404.259, 406.13, 399.388, 411.484, 405.388, 405.678, 407.678, 403.581, 403.291, 406.259, 403.968, 407.13, 398.097, 403.871, 406.549, 409.42, 406.858, 404.536, 403.084, 410.761, 410.665, 403.471] SBS40 ACROSS_ALL_CANCER_TYPES 21 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 3 91.769 1.963 0.308 2.847 4.607 3.688 0.332 0.0 0.0 inf [3.308, 3.769, 3.385, 4.038, 3.962, 3.615, 3.314, 4.045, 4.122, 3.737, 3.891, 3.506, 3.66, 3.429, 3.468, 3.968, 3.627, 3.896, 3.473, 3.473, 3.742, 3.319, 3.558, 3.674, 4.251, 3.905, 4.02, 3.328, 3.943, 3.597, 3.597, 3.481, 3.712, 3.53, 4.607, 3.622, 4.083, 3.699, 4.249, 3.788, 4.211, 3.557, 3.595, 3.48, 4.158, 3.928, 3.351, 3.504, 3.158, 3.735, 3.71, 3.633, 2.979, 4.325, 3.441, 3.825, 3.479, 3.171, 3.248, 4.171, 3.594, 3.441, 3.733, 3.849, 3.272, 2.964, 4.335, 3.489, 3.707, 3.702, 3.894, 3.433, 3.471, 3.856, 4.048, 3.817, 3.433, 3.856, 4.078, 3.54, 2.847, 3.732, 3.424, 3.732, 3.924, 2.886, 3.271, 3.494, 4.263, 3.648, 4.241, 3.741, 3.51, 3.587, 3.702, 4.279, 3.625, 3.895, 3.514, 3.88] SBS40 ACROSS_ALL_CANCER_TYPES 4 34.0 1.531 0.24 0.524 0.667 0.547 0.028 0.0 0.0 inf [0.524, 0.524, 0.524, 0.619, 0.524, 0.524, 0.571, 0.524, 0.571, 0.524, 0.524, 0.524, 0.524, 0.571, 0.524, 0.524, 0.524, 0.524, 0.571, 0.524, 0.524, 0.571, 0.524, 0.524, 0.524, 0.524, 0.524, 0.619, 0.524, 0.571, 0.619, 0.619, 0.524, 0.524, 0.571, 0.524, 0.619, 0.571, 0.524, 0.667, 0.524, 0.571, 0.524, 0.524, 0.571, 0.524, 0.524, 0.667, 0.524, 0.571, 0.524, 0.524, 0.524, 0.524, 0.524, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547, 0.547] SBS40 ACROSS_ALL_CANCER_TYPES 5 16.5 1.217 0.191 0.056 0.056 0.056 0.0 0.0 0.0 inf [0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056, 0.056] SBS40 ACROSS_ALL_CANCER_TYPES 6 7.0 0.845 0.133 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 7 5.267 0.722 0.113 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 8 2.533 0.404 0.063 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] SBS40 ACROSS_ALL_CANCER_TYPES 9 3.364 0.527 0.083 0.0 0.0 0.0 0.0 0.0 0.0 inf [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]