# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	dna_element	encode_element_list	fold_change_list	avg_fold_change	p_value_list	combined_p_value	q_value
SBS38	Skin-Melanoma	H3K27ac-human	['ENCFF731TOU_foreskin-fibroblast_Normal_H3K27ac-human', 'ENCFF704UVU_foreskin-melanocyte_Normal_H3K27ac-human']	[0.913, 0.875]	0.894	[4.557539990538621e-06, 1.0090814285538193e-05]	1.1406545338734429e-09	3.684083709151852e-09
SBS38	Skin-Melanoma	H3K27me3-human	['ENCFF260QSX_foreskin-fibroblast_Normal_H3K27me3-human', 'ENCFF640WPP_foreskin-melanocyte_Normal_H3K27me3-human']	[0.901, 0.802]	0.852	[2.2507454157914486e-17, 2.2563573189376825e-22]	4.528780699471411e-37	2.544206668209634e-36
SBS38	Skin-Melanoma	H3K36me3-human	['ENCFF778WQB_foreskin-fibroblast_Normal_H3K36me3-human', 'ENCFF377DZS_foreskin-melanocyte_Normal_H3K36me3-human']	[0.986, 0.975]	0.98	[0.11003075290779787, 0.004721716360389086]	0.004448550602077098	0.008950754410157224
SBS38	Skin-Melanoma	H3K4me1-human	['ENCFF772YVC_foreskin-fibroblast_Normal_H3K4me1-human', 'ENCFF234OVO_foreskin-melanocyte_Normal_H3K4me1-human']	[0.936, 1.002]	0.969	[1.6413378093909902e-16, 0.8742762145457674]	5.3783447668523e-15	2.0574983918656308e-14
SBS38	Skin-Melanoma	H3K4me3-human	['ENCFF644IVA_foreskin-fibroblast_Normal_H3K4me3-human', 'ENCFF499KTB_foreskin-melanocyte_Normal_H3K4me3-human', 'ENCFF496WOM_lower-leg-skin_Normal_H3K4me3-human']	[0.857, 0.86, 0.778]	0.832	[9.502764832235802e-11, 7.091448112545165e-14, 1.1147430400333622e-19]	3.607278063243205e-39	2.0845069169674962e-38
SBS38	Skin-Melanoma	H3K9ac-human	['ENCFF973JPP_foreskin-melanocyte_Normal_H3K9ac-human']	[0.754]	0.754	[6.402787265510129e-16]	6.402787265510114e-16	2.5171613460822034e-15
SBS38	Skin-Melanoma	H3K9me3-human	['ENCFF342TCS_foreskin-fibroblast_Normal_H3K9me3-human', 'ENCFF849GBJ_foreskin-melanocyte_Normal_H3K9me3-human']	[1.007, 0.987]	0.997	[0.3799415366193155, 0.3539598269097317]	0.40430068157394167	0.5040835554312206