# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
# For real mutations on genic (transcribed:T, untranscribed:U and bitranscribed:B) and intergenic (nontranscribed:N) regions averaged across cancer types.
MutationType	Across_All_Cancer_Types
T:A[C>A]A	44.0
U:A[C>A]A	29.0
B:A[C>A]A	0.0
N:A[C>A]A	167.0
T:A[C>A]C	25.0
U:A[C>A]C	13.5
B:A[C>A]C	0.0
N:A[C>A]C	97.0
T:A[C>A]G	2.5
U:A[C>A]G	1.5
B:A[C>A]G	0.0
N:A[C>A]G	13.0
T:A[C>A]T	14.5
U:A[C>A]T	17.0
B:A[C>A]T	0.0
N:A[C>A]T	103.5
T:A[C>G]A	4.5
U:A[C>G]A	2.5
B:A[C>G]A	0.0
N:A[C>G]A	28.0
T:A[C>G]C	3.5
U:A[C>G]C	1.5
B:A[C>G]C	0.0
N:A[C>G]C	13.5
T:A[C>G]G	0.0
U:A[C>G]G	0.5
B:A[C>G]G	0.0
N:A[C>G]G	3.0
T:A[C>G]T	3.5
U:A[C>G]T	2.5
B:A[C>G]T	0.0
N:A[C>G]T	21.0
T:A[C>T]A	7.5
U:A[C>T]A	5.5
B:A[C>T]A	0.0
N:A[C>T]A	34.5
T:A[C>T]C	2.0
U:A[C>T]C	2.5
B:A[C>T]C	0.0
N:A[C>T]C	15.0
T:A[C>T]G	15.0
U:A[C>T]G	13.5
B:A[C>T]G	0.0
N:A[C>T]G	63.0
T:A[C>T]T	3.0
U:A[C>T]T	1.5
B:A[C>T]T	0.0
N:A[C>T]T	19.0
T:A[T>A]A	6.0
U:A[T>A]A	4.5
B:A[T>A]A	0.0
N:A[T>A]A	36.0
T:A[T>A]C	3.0
U:A[T>A]C	1.5
B:A[T>A]C	0.0
N:A[T>A]C	18.0
T:A[T>A]G	1.5
U:A[T>A]G	0.5
B:A[T>A]G	0.0
N:A[T>A]G	8.5
T:A[T>A]T	7.5
U:A[T>A]T	5.0
B:A[T>A]T	0.0
N:A[T>A]T	36.5
T:A[T>C]A	4.5
U:A[T>C]A	2.5
B:A[T>C]A	0.0
N:A[T>C]A	22.5
T:A[T>C]C	2.5
U:A[T>C]C	1.0
B:A[T>C]C	0.0
N:A[T>C]C	11.5
T:A[T>C]G	2.0
U:A[T>C]G	1.0
B:A[T>C]G	0.0
N:A[T>C]G	9.5
T:A[T>C]T	4.0
U:A[T>C]T	3.0
B:A[T>C]T	0.0
N:A[T>C]T	21.0
T:A[T>G]A	1.5
U:A[T>G]A	1.0
B:A[T>G]A	0.0
N:A[T>G]A	13.5
T:A[T>G]C	0.0
U:A[T>G]C	0.5
B:A[T>G]C	0.0
N:A[T>G]C	5.5
T:A[T>G]G	2.0
U:A[T>G]G	3.5
B:A[T>G]G	0.0
N:A[T>G]G	24.0
T:A[T>G]T	3.0
U:A[T>G]T	4.0
B:A[T>G]T	0.0
N:A[T>G]T	24.5
T:C[C>A]A	992.0
U:C[C>A]A	928.5
B:C[C>A]A	3.5
N:C[C>A]A	4718.0
T:C[C>A]C	133.5
U:C[C>A]C	124.0
B:C[C>A]C	0.0
N:C[C>A]C	656.5
T:C[C>A]G	123.5
U:C[C>A]G	131.5
B:C[C>A]G	0.5
N:C[C>A]G	570.5
T:C[C>A]T	404.5
U:C[C>A]T	416.0
B:C[C>A]T	2.5
N:C[C>A]T	2156.5
T:C[C>G]A	0.5
U:C[C>G]A	1.5
B:C[C>G]A	0.0
N:C[C>G]A	12.5
T:C[C>G]C	0.0
U:C[C>G]C	1.0
B:C[C>G]C	0.0
N:C[C>G]C	4.0
T:C[C>G]G	0.5
U:C[C>G]G	0.0
B:C[C>G]G	0.0
N:C[C>G]G	3.0
T:C[C>G]T	1.5
U:C[C>G]T	1.5
B:C[C>G]T	0.0
N:C[C>G]T	7.0
T:C[C>T]A	7.0
U:C[C>T]A	8.5
B:C[C>T]A	0.0
N:C[C>T]A	45.0
T:C[C>T]C	11.5
U:C[C>T]C	14.0
B:C[C>T]C	0.0
N:C[C>T]C	57.5
T:C[C>T]G	4.5
U:C[C>T]G	5.0
B:C[C>T]G	0.0
N:C[C>T]G	21.5
T:C[C>T]T	6.5
U:C[C>T]T	7.0
B:C[C>T]T	0.0
N:C[C>T]T	41.5
T:C[T>A]A	1.5
U:C[T>A]A	0.5
B:C[T>A]A	0.0
N:C[T>A]A	12.5
T:C[T>A]C	1.5
U:C[T>A]C	1.5
B:C[T>A]C	0.0
N:C[T>A]C	15.0
T:C[T>A]G	4.0
U:C[T>A]G	4.0
B:C[T>A]G	0.0
N:C[T>A]G	23.5
T:C[T>A]T	3.5
U:C[T>A]T	3.0
B:C[T>A]T	0.0
N:C[T>A]T	28.5
T:C[T>C]A	1.0
U:C[T>C]A	1.5
B:C[T>C]A	0.0
N:C[T>C]A	13.5
T:C[T>C]C	3.0
U:C[T>C]C	5.0
B:C[T>C]C	0.0
N:C[T>C]C	23.0
T:C[T>C]G	3.5
U:C[T>C]G	3.5
B:C[T>C]G	0.0
N:C[T>C]G	20.0
T:C[T>C]T	5.5
U:C[T>C]T	6.0
B:C[T>C]T	0.0
N:C[T>C]T	41.5
T:C[T>G]A	0.5
U:C[T>G]A	0.5
B:C[T>G]A	0.0
N:C[T>G]A	7.0
T:C[T>G]C	1.0
U:C[T>G]C	0.5
B:C[T>G]C	0.0
N:C[T>G]C	6.5
T:C[T>G]G	3.0
U:C[T>G]G	4.0
B:C[T>G]G	0.0
N:C[T>G]G	26.5
T:C[T>G]T	13.5
U:C[T>G]T	19.0
B:C[T>G]T	0.0
N:C[T>G]T	87.0
T:G[C>A]A	24.5
U:G[C>A]A	23.5
B:G[C>A]A	0.0
N:G[C>A]A	149.0
T:G[C>A]C	9.5
U:G[C>A]C	7.0
B:G[C>A]C	0.0
N:G[C>A]C	44.5
T:G[C>A]G	0.5
U:G[C>A]G	0.0
B:G[C>A]G	0.0
N:G[C>A]G	6.5
T:G[C>A]T	16.5
U:G[C>A]T	18.0
B:G[C>A]T	0.0
N:G[C>A]T	99.0
T:G[C>G]A	0.0
U:G[C>G]A	1.0
B:G[C>G]A	0.0
N:G[C>G]A	10.5
T:G[C>G]C	1.0
U:G[C>G]C	0.5
B:G[C>G]C	0.0
N:G[C>G]C	5.5
T:G[C>G]G	2.0
U:G[C>G]G	1.5
B:G[C>G]G	0.0
N:G[C>G]G	8.5
T:G[C>G]T	0.5
U:G[C>G]T	0.5
B:G[C>G]T	0.0
N:G[C>G]T	4.5
T:G[C>T]A	4.0
U:G[C>T]A	2.5
B:G[C>T]A	0.0
N:G[C>T]A	23.0
T:G[C>T]C	3.0
U:G[C>T]C	5.0
B:G[C>T]C	0.0
N:G[C>T]C	20.5
T:G[C>T]G	11.5
U:G[C>T]G	12.5
B:G[C>T]G	0.0
N:G[C>T]G	53.5
T:G[C>T]T	4.0
U:G[C>T]T	5.0
B:G[C>T]T	0.0
N:G[C>T]T	27.5
T:G[T>A]A	2.0
U:G[T>A]A	1.0
B:G[T>A]A	0.0
N:G[T>A]A	8.0
T:G[T>A]C	0.0
U:G[T>A]C	1.0
B:G[T>A]C	0.0
N:G[T>A]C	7.5
T:G[T>A]G	2.0
U:G[T>A]G	1.5
B:G[T>A]G	0.0
N:G[T>A]G	11.0
T:G[T>A]T	1.5
U:G[T>A]T	1.5
B:G[T>A]T	0.0
N:G[T>A]T	18.0
T:G[T>C]A	3.0
U:G[T>C]A	2.5
B:G[T>C]A	0.0
N:G[T>C]A	16.0
T:G[T>C]C	3.5
U:G[T>C]C	4.5
B:G[T>C]C	0.0
N:G[T>C]C	24.0
T:G[T>C]G	3.0
U:G[T>C]G	2.5
B:G[T>C]G	0.0
N:G[T>C]G	18.0
T:G[T>C]T	5.0
U:G[T>C]T	9.0
B:G[T>C]T	0.0
N:G[T>C]T	40.0
T:G[T>G]A	0.5
U:G[T>G]A	1.0
B:G[T>G]A	0.0
N:G[T>G]A	4.5
T:G[T>G]C	2.5
U:G[T>G]C	1.5
B:G[T>G]C	0.0
N:G[T>G]C	7.0
T:G[T>G]G	7.5
U:G[T>G]G	14.0
B:G[T>G]G	0.0
N:G[T>G]G	40.5
T:G[T>G]T	9.5
U:G[T>G]T	11.0
B:G[T>G]T	0.0
N:G[T>G]T	38.0
T:T[C>A]A	50.5
U:T[C>A]A	41.5
B:T[C>A]A	0.5
N:T[C>A]A	221.0
T:T[C>A]C	23.5
U:T[C>A]C	17.5
B:T[C>A]C	0.0
N:T[C>A]C	115.0
T:T[C>A]G	1.5
U:T[C>A]G	2.5
B:T[C>A]G	0.0
N:T[C>A]G	15.5
T:T[C>A]T	77.0
U:T[C>A]T	93.0
B:T[C>A]T	0.0
N:T[C>A]T	435.5
T:T[C>G]A	8.0
U:T[C>G]A	5.5
B:T[C>G]A	0.0
N:T[C>G]A	35.0
T:T[C>G]C	2.5
U:T[C>G]C	4.0
B:T[C>G]C	0.0
N:T[C>G]C	19.5
T:T[C>G]G	1.5
U:T[C>G]G	0.5
B:T[C>G]G	0.0
N:T[C>G]G	7.0
T:T[C>G]T	9.0
U:T[C>G]T	12.5
B:T[C>G]T	0.0
N:T[C>G]T	53.0
T:T[C>T]A	12.0
U:T[C>T]A	13.5
B:T[C>T]A	0.0
N:T[C>T]A	77.0
T:T[C>T]C	16.5
U:T[C>T]C	20.5
B:T[C>T]C	0.0
N:T[C>T]C	101.0
T:T[C>T]G	5.0
U:T[C>T]G	5.5
B:T[C>T]G	0.0
N:T[C>T]G	29.5
T:T[C>T]T	15.0
U:T[C>T]T	21.0
B:T[C>T]T	0.0
N:T[C>T]T	88.5
T:T[T>A]A	6.5
U:T[T>A]A	7.5
B:T[T>A]A	0.0
N:T[T>A]A	39.5
T:T[T>A]C	0.0
U:T[T>A]C	0.5
B:T[T>A]C	0.0
N:T[T>A]C	5.0
T:T[T>A]G	0.0
U:T[T>A]G	0.0
B:T[T>A]G	0.0
N:T[T>A]G	4.5
T:T[T>A]T	2.5
U:T[T>A]T	4.0
B:T[T>A]T	0.0
N:T[T>A]T	24.5
T:T[T>C]A	1.0
U:T[T>C]A	1.5
B:T[T>C]A	0.0
N:T[T>C]A	16.5
T:T[T>C]C	3.0
U:T[T>C]C	5.0
B:T[T>C]C	0.0
N:T[T>C]C	26.5
T:T[T>C]G	1.5
U:T[T>C]G	1.5
B:T[T>C]G	0.0
N:T[T>C]G	15.5
T:T[T>C]T	3.0
U:T[T>C]T	7.0
B:T[T>C]T	0.0
N:T[T>C]T	33.5
T:T[T>G]A	0.5
U:T[T>G]A	1.0
B:T[T>G]A	0.0
N:T[T>G]A	8.5
T:T[T>G]C	0.0
U:T[T>G]C	0.0
B:T[T>G]C	0.0
N:T[T>G]C	4.5
T:T[T>G]G	3.0
U:T[T>G]G	4.5
B:T[T>G]G	0.0
N:T[T>G]G	20.0
T:T[T>G]T	9.5
U:T[T>G]T	17.0
B:T[T>G]T	0.0
N:T[T>G]T	69.0

# There must be at least 1000 mutations on the strands.
# Signature and mutation type must have at least 5% of all signature mutations on the strands.
# Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1.
cancer_type	signature	mutation_type	genic_real_count	intergenic_real_count	genic_mean_sims_count	intergenic_mean_sims_count	genic_versus_intergenic_p_value	genic_versus_intergenic_q_value	percentage_of_mutations_on_strands	signature_number_of_mutations_on_strands	significant_strand	FC_REAL	FC_SIMS	FC	fold_change_1.1	fold_change_1.2	fold_change_1.3	fold_change_1.5	fold_change_1.75	fold_change_2+	Transcribed_real_count	Transcribed_mean_sims_count	Transcribed_min_sims_count	Transcribed_max_sims_count	Transcribed_sims_count_list	UnTranscribed_real_count	UnTranscribed_mean_sims_count	UnTranscribed_min_sims_count	UnTranscribed_max_sims_count	UnTranscribed_sims_count_list	NonTranscribed_real_count	NonTranscribed_mean_sims_count	NonTranscribed_min_sims_count	NonTranscribed_max_sims_count	NonTranscribed_sims_count_list
Skin-Melanoma	SBS38	C>A	7905.0	19134.0	11970.23	15166.68	5.679399753777532e-284	1.8443361096965486e-282	98.993	27314.0	Intergenic	2.42	1.267	1.91	1	1	1	1	1		3990.0	6127.64	5950.0	6310.0	[6065, 6272, 6148, 6126, 6087, 6046, 6187, 6107, 6088, 6147, 6150, 6110, 6150, 6160, 6110, 6095, 6194, 6051, 6134, 6056, 6125, 6124, 6122, 6163, 6126, 6144, 6202, 6197, 6074, 6039, 6146, 6136, 6095, 6262, 6043, 6031, 6071, 6055, 6247, 5981, 6274, 6156, 6195, 6026, 6109, 6075, 6164, 6212, 6310, 6057, 6066, 6213, 6124, 6133, 6080, 6209, 6167, 6132, 6196, 6218, 6110, 6076, 6065, 6096, 6101, 6165, 6045, 6177, 6259, 6061, 5996, 6025, 6160, 6261, 6147, 6072, 6034, 6246, 6137, 6071, 6141, 6248, 6050, 6127, 6177, 6190, 6151, 6221, 5950, 6149, 6051, 6138, 6029, 6076, 6039, 6138, 6043, 6189, 6228, 6143]	3915.0	5842.59	5674.0	6013.0	[5879, 5858, 5783, 5817, 5798, 5798, 5742, 5814, 5815, 5861, 5806, 5795, 5893, 5843, 5850, 5888, 5830, 5795, 5918, 6004, 5845, 5818, 5991, 5904, 5861, 5812, 5720, 5860, 5902, 5863, 5700, 5910, 5902, 5786, 5793, 5879, 5997, 5823, 5860, 6004, 5712, 5722, 5804, 5877, 5814, 5900, 5883, 5674, 5722, 5879, 5852, 5823, 6013, 5874, 5782, 5779, 5788, 5705, 5909, 5717, 5979, 5884, 5930, 5810, 5868, 5926, 5911, 5858, 5702, 5930, 5811, 5934, 5889, 5777, 5766, 5854, 5780, 5909, 5837, 5971, 5795, 5804, 5918, 5772, 5884, 5935, 5689, 5713, 6008, 5812, 5962, 5910, 5841, 5749, 5822, 5836, 5801, 5823, 5867, 5746]	19134.0	15166.68	14998.0	15333.0	[15191, 15026, 15191, 15207, 15260, 15284, 15210, 15221, 15250, 15153, 15160, 15236, 15091, 15136, 15197, 15154, 15104, 15290, 15072, 15077, 15180, 15179, 15052, 15066, 15146, 15168, 15201, 15078, 15146, 15242, 15272, 15082, 15157, 15106, 15296, 15229, 15074, 15250, 15029, 15144, 15138, 15248, 15145, 15214, 15190, 15165, 15079, 15249, 15099, 15186, 15223, 15127, 15003, 15140, 15271, 15143, 15173, 15307, 15044, 15194, 15073, 15188, 15148, 15236, 15162, 15070, 15172, 15128, 15200, 15168, 15333, 15160, 15096, 15085, 15218, 15203, 15295, 14998, 15165, 15089, 15192, 15099, 15173, 15218, 15057, 15010, 15290, 15201, 15185, 15168, 15114, 15086, 15282, 15304, 15277, 15175, 15270, 15141, 15054, 15240]
Skin-Melanoma	SBS38	C>G	0.0	0.0	0.0	0.0	1.0	1.0	0.0	27314.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
Skin-Melanoma	SBS38	C>T	51.0	85.0	65.27	70.42	0.08622534627966308	0.25205189816515067	0.498	27314.0	Intergenic	1.667	1.079	1.545	1	1	1	1			26.0	35.06	23.0	46.0	[42, 43, 33, 33, 41, 33, 38, 28, 33, 32, 44, 36, 33, 44, 38, 32, 36, 39, 30, 31, 31, 44, 42, 38, 35, 46, 32, 40, 39, 23, 30, 26, 29, 29, 24, 38, 40, 26, 37, 29, 29, 35, 38, 42, 32, 37, 43, 27, 36, 45, 35, 36, 24, 33, 36, 36, 34, 35, 38, 26, 33, 35, 31, 35, 29, 41, 35, 27, 37, 35, 45, 40, 33, 42, 38, 33, 30, 32, 28, 46, 36, 37, 34, 38, 38, 37, 36, 40, 35, 44, 39, 29, 31, 36, 29, 30, 36, 32, 34, 36]	25.0	30.21	20.0	42.0	[31, 32, 31, 39, 29, 29, 33, 32, 33, 28, 25, 29, 26, 32, 30, 33, 27, 31, 30, 26, 31, 24, 33, 35, 20, 27, 30, 31, 31, 29, 29, 40, 35, 24, 35, 29, 25, 42, 36, 24, 27, 25, 30, 21, 32, 24, 34, 37, 25, 28, 31, 34, 27, 33, 31, 35, 38, 32, 29, 34, 37, 39, 26, 31, 28, 22, 37, 28, 28, 26, 27, 33, 23, 34, 33, 27, 30, 30, 30, 28, 31, 26, 34, 22, 35, 32, 34, 31, 38, 22, 29, 40, 26, 31, 33, 33, 24, 25, 20, 35]	85.0	70.42	58.0	85.0	[62, 60, 71, 65, 66, 73, 64, 77, 69, 75, 66, 71, 77, 60, 67, 70, 72, 65, 75, 78, 74, 70, 61, 63, 81, 64, 73, 65, 66, 83, 76, 69, 71, 82, 76, 68, 71, 68, 63, 83, 81, 75, 68, 73, 71, 75, 58, 73, 74, 62, 70, 67, 85, 70, 68, 66, 64, 68, 68, 75, 67, 61, 79, 70, 78, 72, 65, 80, 72, 74, 63, 63, 81, 60, 65, 75, 76, 73, 77, 61, 69, 74, 67, 76, 63, 66, 66, 64, 64, 70, 69, 67, 79, 69, 74, 72, 76, 78, 82, 64]
Skin-Melanoma	SBS38	T>A	0.0	0.0	0.0	0.0	1.0	1.0	0.0	27314.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
Skin-Melanoma	SBS38	T>C	0.0	0.0	0.0	0.0	1.0	1.0	0.0	27314.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
Skin-Melanoma	SBS38	T>G	40.0	99.0	59.37	80.39	0.023928393301055388	0.08045664168260248	0.509	27314.0	Intergenic	2.475	1.354	1.828	1	1	1	1	1		20.0	27.89	19.0	40.0	[30, 23, 27, 20, 26, 30, 29, 32, 21, 28, 29, 40, 32, 24, 33, 29, 23, 20, 27, 24, 27, 38, 28, 27, 33, 24, 27, 27, 22, 26, 28, 28, 27, 26, 28, 30, 24, 32, 30, 26, 25, 31, 26, 24, 29, 33, 32, 23, 26, 31, 30, 32, 27, 22, 21, 29, 27, 29, 35, 31, 26, 31, 19, 27, 26, 33, 25, 23, 24, 34, 26, 28, 25, 31, 40, 36, 34, 31, 26, 32, 20, 36, 26, 31, 23, 36, 30, 26, 29, 29, 28, 23, 26, 30, 26, 19, 24, 34, 23, 25]	20.0	31.48	20.0	43.0	[31, 29, 21, 29, 36, 28, 38, 23, 34, 31, 31, 27, 35, 41, 30, 26, 38, 31, 37, 35, 27, 34, 31, 36, 27, 31, 32, 32, 37, 25, 32, 27, 41, 27, 36, 29, 24, 35, 30, 39, 30, 34, 34, 28, 31, 26, 24, 35, 24, 34, 40, 28, 29, 43, 38, 29, 37, 28, 33, 34, 26, 28, 29, 31, 36, 32, 40, 30, 33, 29, 36, 29, 33, 25, 29, 20, 31, 30, 30, 28, 36, 33, 28, 27, 40, 32, 27, 38, 37, 25, 34, 33, 36, 27, 29, 31, 37, 30, 28, 33]	99.0	80.39	67.0	92.0	[78, 87, 91, 92, 78, 82, 73, 84, 84, 81, 79, 74, 73, 74, 76, 85, 80, 88, 75, 81, 85, 67, 80, 78, 79, 84, 81, 81, 80, 89, 79, 84, 71, 87, 77, 82, 91, 73, 80, 74, 85, 75, 80, 88, 80, 81, 84, 82, 89, 75, 70, 80, 84, 75, 80, 82, 75, 82, 74, 75, 87, 84, 91, 82, 81, 74, 74, 86, 83, 77, 79, 82, 81, 84, 71, 84, 74, 78, 83, 80, 84, 72, 87, 81, 76, 72, 82, 76, 75, 85, 77, 84, 77, 84, 84, 90, 79, 76, 89, 81]

Summary across all cancer types
signature	mutation_type	strand	fold_change_1.1	len(fold_change_1.1_cancer_types)	fold_change_1.2	len(fold_change_1.2_cancer_types)	fold_change_1.3	len(fold_change_1.3_cancer_types)	fold_change_1.5	len(fold_change_1.5_cancer_types)	fold_change_1.75	len(fold_change_1.75_cancer_types)	fold_change_2+	len(fold_change_2+_cancer_types)	all_cancer_types_list	len(all_cancer_types_list)	avg_fold_change
SBS38	C>A	Intergenic	['Skin-Melanoma']	1	['Skin-Melanoma']	1	['Skin-Melanoma']	1	['Skin-Melanoma']	1	['Skin-Melanoma']	1	[]	0	['Skin-Melanoma']	1	1.75