# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	cutoff	number_of_mutations	average_probability	file_name	pearson_corr	pearson_p_value	pearson_q_value	real_average_number_of_overlaps	sims_average_number_of_overlaps	avg_real_signal	sim_data_avg_signal	fold_change	real_average_signal_array	sims_average_signal_array
SBS37	ColoRect-AdenoCA	0.69	23865	0.75	SBS37_ENCFF108TAJ_transverse-colon_Normal_CTCF-human_AverageSignalArray.txt				62.66	92.814	105.074	125.023	0.84	[119.057, 119.057, 119.057, 119.057, 119.057, 119.057, 119.057, 118.229, 118.229, 118.229, 118.229, 118.229, 118.229, 118.229, 118.229, 118.229, 119.49, 119.49, 119.667, 119.667, 119.797, 119.797, 119.867, 120.919, 122.752, 122.752, 125.334, 125.334, 124.617, 124.617, 123.967, 123.967, 125.488, 125.488, 125.488, 127.861, 127.861, 127.736, 127.736, 127.736, 127.736, 128.897, 128.897, 128.897, 128.852, 127.682, 126.335, 125.301, 125.004, 126.439, 126.013, 126.013, 125.422, 125.422, 125.422, 124.647, 124.647, 124.721, 125.7, 125.7, 126.837, 124.808, 124.808, 124.808, 124.808, 124.808, 125.292, 124.107, 123.958, 122.9, 122.9, 122.9, 122.9, 122.9, 122.9, 122.9, 122.9, 121.721, 121.721, 121.721, 121.362, 121.362, 123.569, 123.569, 123.569, 123.569, 123.569, 123.569, 123.569, 125.111, 125.191, 124.975, 127.208, 127.208, 127.208, 127.208, 127.208, 129.385, 129.385, 129.385, 130.125, 130.125, 130.125, 130.125, 130.125, 128.891, 127.631, 127.631, 127.631, 127.631, 126.496, 124.581, 124.88, 124.88, 125.058, 125.058, 125.058, 124.483, 123.566, 123.566, 123.566, 123.566, 123.566, 123.981, 123.981, 125.151, 125.151, 125.151, 121.887, 121.887, 121.887, 121.887, 121.887, 121.887, 121.887, 122.005, 122.005, 122.005, 120.74, 120.74, 119.575, 119.575, 119.575, 119.575, 119.575, 119.575, 119.575, 119.575, 119.111, 119.111, 119.935, 119.935, 119.591, 119.591, 119.591, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 120.514, 119.573, 119.995, 119.995, 121.108, 121.108, 120.815, 120.815, 121.293, 121.293, 123.005, 123.005, 121.873, 121.873, 123.009, 123.009, 123.009, 124.072, 124.072, 124.072, 124.876, 126.438, 126.438, 126.438, 126.438, 125.273, 125.273, 125.273, 125.273, 125.273, 125.273, 125.323, 125.323, 124.962, 124.295, 124.295, 123.566, 123.566, 123.617, 123.617, 123.617, 123.617, 123.617, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 123.382, 124.495, 124.495, 124.495, 123.741, 123.741, 123.741, 123.295, 123.119, 123.119, 122.336, 122.336, 122.336, 122.181, 122.181, 122.181, 123.065, 123.065, 124.124, 124.124, 124.124, 124.124, 125.24, 125.24, 125.24, 125.24, 125.24, 125.24, 125.24, 125.24, 125.486, 125.486, 125.486, 125.492, 125.492, 125.492, 125.492, 125.492, 123.784, 123.784, 123.784, 123.784, 123.784, 123.784, 125.489, 125.489, 125.489, 124.961, 123.751, 122.835, 122.295, 122.271, 122.271, 122.271, 122.215, 122.215, 122.215, 122.215, 122.215, 122.215, 121.556, 121.556, 121.556, 121.556, 121.556, 121.556, 121.556, 121.556, 121.556, 121.556, 121.556, 121.556, 122.06, 121.755, 121.149, 120.819, 120.819, 120.819, 120.819, 120.819, 121.966, 121.966, 121.966, 122.176, 122.176, 122.176, 122.176, 122.176, 122.668, 122.668, 122.668, 122.668, 122.668, 122.668, 122.668, 122.668, 122.826, 122.826, 122.826, 122.826, 122.826, 122.826, 122.826, 122.826, 121.825, 121.825, 121.825, 122.391, 122.391, 122.391, 119.395, 119.395, 119.395, 119.395, 119.395, 120.255, 120.243, 120.243, 120.243, 121.248, 120.441, 120.441, 120.441, 120.441, 119.7, 117.488, 117.488, 117.488, 117.488, 117.488, 117.699, 117.699, 117.699, 117.699, 117.699, 117.699, 114.782, 114.782, 115.107, 113.427, 113.427, 113.427, 113.427, 113.427, 113.427, 113.427, 113.427, 112.58, 111.422, 108.959, 108.959, 110.242, 110.242, 109.164, 108.205, 109.266, 106.207, 106.207, 106.223, 105.568, 106.388, 105.379, 105.379, 105.379, 105.379, 106.437, 106.437, 105.352, 104.345, 103.91, 103.673, 104.676, 104.676, 104.676, 104.676, 106.402, 106.402, 105.741, 105.741, 105.741, 105.183, 106.08, 106.08, 106.208, 106.208, 103.665, 103.665, 103.665, 101.888, 101.888, 101.888, 102.731, 103.538, 103.538, 103.538, 103.538, 103.538, 103.538, 102.902, 101.102, 101.892, 101.892, 101.896, 101.896, 101.896, 101.896, 101.896, 101.896, 102.562, 102.562, 102.562, 102.562, 101.8, 101.8, 101.8, 101.8, 102.603, 102.603, 107.375, 107.375, 107.375, 107.375, 107.375, 107.375, 104.027, 104.027, 104.027, 104.636, 104.636, 104.636, 104.636, 104.636, 104.636, 104.636, 105.069, 105.069, 108.276, 106.583, 104.673, 104.673, 104.673, 104.673, 104.673, 104.673, 105.7, 105.7, 105.7, 105.7, 107.026, 107.026, 106.282, 106.282, 106.801, 106.801, 106.801, 106.801, 104.578, 104.578, 104.715, 103.959, 102.965, 102.965, 102.965, 106.208, 106.614, 106.614, 106.614, 106.257, 105.856, 105.856, 105.856, 105.856, 105.856, 105.856, 105.856, 105.856, 105.856, 105.856, 105.856, 106.736, 106.475, 107.306, 107.306, 107.306, 107.306, 107.306, 107.858, 107.218, 107.218, 107.218, 107.218, 107.218, 107.218, 105.845, 105.845, 105.845, 105.845, 105.845, 108.577, 108.577, 108.577, 106.698, 106.698, 107.598, 105.902, 105.902, 105.902, 105.902, 105.902, 105.902, 104.733, 104.733, 104.733, 100.36, 100.956, 100.956, 101.518, 98.889, 98.889, 99.633, 98.688, 98.688, 100.233, 100.233, 100.233, 100.233, 100.233, 100.233, 100.233, 100.233, 100.281, 100.281, 100.281, 100.281, 103.227, 103.227, 103.227, 103.227, 103.227, 104.284, 105.604, 101.799, 101.799, 101.799, 102.439, 102.439, 101.393, 101.393, 102.814, 102.814, 102.814, 102.814, 102.216, 102.216, 102.216, 101.613, 103.982, 103.881, 103.881, 104.072, 104.072, 105.552, 105.552, 105.552, 107.055, 107.055, 107.055, 107.055, 107.055, 107.055, 105.337, 105.337, 108.364, 108.364, 109.552, 109.682, 109.682, 109.682, 109.682, 111.034, 110.335, 110.335, 110.335, 110.335, 110.335, 110.335, 110.559, 110.559, 110.559, 110.559, 108.58, 108.58, 108.58, 107.53, 107.53, 107.53, 106.56, 106.56, 106.082, 106.082, 106.082, 106.082, 106.941, 106.941, 106.941, 107.566, 107.566, 107.541, 107.541, 107.123, 105.983, 105.983, 105.983, 107.098, 106.043, 105.401, 105.401, 106.219, 106.219, 106.219, 106.219, 106.219, 106.219, 104.533, 104.533, 104.533, 104.533, 104.533, 104.533, 103.8, 103.8, 103.8, 103.8, 103.8, 103.8, 103.432, 103.432, 103.997, 105.584, 107.817, 108.603, 108.603, 110.273, 110.273, 110.273, 110.273, 110.273, 108.238, 108.238, 108.238, 108.238, 108.238, 107.098, 107.098, 107.098, 107.098, 107.098, 108.109, 108.109, 108.109, 108.738, 108.738, 108.738, 108.738, 108.738, 108.738, 110.522, 110.522, 110.522, 110.279, 110.279, 110.279, 109.573, 109.573, 109.573, 113.275, 113.275, 113.275, 113.275, 112.576, 112.708, 112.83, 113.341, 112.377, 112.377, 112.377, 112.377, 112.377, 112.377, 111.771, 111.771, 111.771, 112.635, 112.635, 112.635, 112.635, 112.635, 112.635, 112.635, 113.509, 113.509, 113.509, 113.509, 111.536, 113.503, 113.157, 111.685, 111.685, 111.685, 111.845, 111.23, 110.508, 110.508, 110.508, 111.109, 111.109, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.651, 111.903, 111.903, 111.903, 111.903, 111.903, 112.858, 112.858, 114.283, 115.55, 115.55, 115.518, 115.518, 115.518, 115.518, 115.518, 115.111, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 115.482, 116.373, 114.232, 114.232, 114.232, 114.427, 113.725, 113.725, 113.725, 113.725, 114.187, 113.572, 114.781, 114.781, 114.325, 114.325, 114.325, 115.246, 115.246, 115.886, 115.886, 115.143, 117.0, 117.0, 117.0, 117.0, 117.0, 117.0, 116.431, 118.584, 118.584, 118.584, 118.584, 118.708, 118.708, 119.768, 119.768, 121.996, 122.06, 121.243, 122.92, 122.92, 122.92, 122.137, 123.005, 124.32, 124.32, 124.32, 123.308, 123.308, 123.308, 123.143, 123.143, 123.143, 123.143, 123.143, 122.091, 122.636, 123.68, 123.68, 123.68, 123.68, 123.68, 123.68, 124.861, 125.991, 125.88, 125.831, 125.831, 125.831, 125.831, 124.846, 124.657, 124.657, 124.639, 124.639, 125.045, 125.205, 125.205, 125.205, 125.205, 125.205, 125.205, 125.205, 125.205, 124.106, 124.106, 123.26, 123.26, 120.996, 120.354, 120.354, 120.354, 119.373, 119.373, 120.09, 120.09, 120.09, 120.09, 118.21, 117.439, 114.678, 115.976, 115.341, 115.341, 115.341, 115.341, 115.341, 115.341, 116.074, 116.074, 116.074, 116.074, 116.074, 116.074, 112.528, 112.528, 112.528, 112.528, 112.528, 111.466, 112.094, 112.163, 112.163, 112.163, 112.163, 112.163, 110.462, 109.987, 109.987, 109.987, 110.134, 110.809, 110.809, 109.851, 109.851, 110.161, 110.161, 108.625, 108.625, 109.26, 109.26, 109.26, 109.26, 109.26, 109.26, 109.26, 108.417, 107.333, 109.921, 109.561, 109.561, 109.561, 109.561, 109.7, 110.85, 109.903, 109.903, 110.078, 110.078, 111.037, 111.271, 111.271, 111.11, 112.209, 112.209, 111.9, 112.184, 112.184, 112.184, 112.184, 112.184, 112.184, 112.184, 112.184, 112.184, 112.184, 114.36, 114.36, 114.787, 114.787, 114.787, 114.787, 115.1, 115.59, 115.59, 116.504, 116.504, 116.504, 116.504, 116.504, 117.062, 117.062, 117.062, 117.062, 117.062, 117.062, 117.062, 117.062, 117.062, 117.062, 117.646, 117.646, 116.976, 116.976, 116.976, 116.91, 117.222, 114.753, 114.753, 114.753, 113.947, 113.947, 115.198, 115.198, 115.198, 115.198, 115.954, 115.248, 114.952]	[126.777, 126.776, 126.877, 126.717, 126.749, 126.659, 126.707, 126.803, 126.815, 126.838, 126.767, 126.776, 126.699, 126.793, 126.74, 126.853, 126.973, 127.063, 127.024, 127.091, 127.072, 127.171, 127.125, 127.125, 127.063, 127.067, 127.005, 127.045, 127.05, 127.141, 127.067, 126.893, 126.891, 126.939, 126.932, 126.96, 127.061, 127.044, 127.147, 127.123, 127.143, 127.129, 126.99, 126.907, 126.87, 126.812, 126.902, 126.848, 126.846, 126.714, 126.633, 126.562, 126.611, 126.546, 126.764, 126.643, 126.672, 126.619, 126.51, 126.523, 126.532, 126.578, 126.649, 126.641, 126.71, 126.695, 126.679, 126.593, 126.581, 126.67, 126.725, 126.714, 126.754, 126.698, 126.719, 126.853, 126.787, 126.679, 126.632, 126.625, 126.613, 126.752, 126.729, 126.737, 126.802, 126.822, 126.764, 126.664, 126.697, 126.703, 126.634, 126.671, 126.684, 126.649, 126.677, 126.691, 126.721, 126.695, 126.837, 126.882, 126.922, 126.968, 127.021, 127.076, 127.118, 127.033, 127.033, 127.176, 127.108, 127.092, 127.105, 127.241, 127.365, 127.418, 127.343, 127.247, 127.343, 127.366, 127.335, 127.249, 127.114, 127.114, 127.158, 127.253, 127.295, 127.31, 127.317, 127.344, 127.306, 127.289, 127.278, 127.287, 127.243, 127.129, 127.115, 127.128, 127.142, 127.059, 127.05, 127.138, 127.092, 127.13, 127.111, 127.223, 127.164, 127.314, 127.267, 127.347, 127.398, 127.363, 127.388, 127.271, 127.285, 127.321, 127.408, 127.29, 127.354, 127.31, 127.243, 127.273, 127.224, 127.184, 127.112, 127.089, 127.14, 127.061, 127.026, 126.985, 126.992, 126.933, 126.827, 126.737, 126.904, 126.836, 126.723, 126.714, 126.639, 126.7, 126.762, 126.682, 126.691, 126.761, 126.859, 126.733, 126.722, 126.648, 126.562, 126.523, 126.659, 126.604, 126.682, 126.673, 126.573, 126.528, 126.607, 126.542, 126.515, 126.592, 126.568, 126.637, 126.67, 126.796, 126.793, 126.837, 126.797, 126.748, 126.745, 126.695, 126.629, 126.715, 126.641, 126.668, 126.631, 126.481, 126.366, 126.351, 126.352, 126.328, 126.469, 126.486, 126.439, 126.4, 126.392, 126.466, 126.465, 126.474, 126.45, 126.489, 126.435, 126.429, 126.302, 126.219, 126.315, 126.416, 126.534, 126.471, 126.505, 126.454, 126.413, 126.446, 126.531, 126.673, 126.525, 126.595, 126.706, 126.779, 126.794, 126.903, 126.791, 126.808, 126.848, 126.796, 126.842, 126.857, 126.812, 126.807, 126.827, 126.825, 126.81, 126.714, 126.677, 126.659, 126.597, 126.625, 126.523, 126.414, 126.478, 126.434, 126.508, 126.53, 126.59, 126.468, 126.488, 126.447, 126.539, 126.602, 126.621, 126.561, 126.54, 126.524, 126.529, 126.473, 126.505, 126.489, 126.475, 126.466, 126.472, 126.525, 126.471, 126.447, 126.362, 126.271, 126.357, 126.35, 126.335, 126.285, 126.291, 126.294, 126.327, 126.326, 126.207, 126.385, 126.285, 126.259, 126.254, 126.006, 126.111, 126.153, 126.201, 126.135, 126.168, 126.201, 126.229, 126.358, 126.398, 126.423, 126.369, 126.421, 126.625, 126.668, 126.651, 126.593, 126.617, 126.474, 126.453, 126.462, 126.447, 126.44, 126.405, 126.433, 126.512, 126.525, 126.43, 126.329, 126.383, 126.286, 126.277, 126.302, 126.302, 126.307, 126.165, 126.11, 126.039, 126.189, 126.084, 126.033, 126.009, 125.964, 126.018, 125.952, 125.905, 125.981, 125.987, 125.943, 125.811, 125.615, 125.502, 125.53, 125.459, 125.473, 125.574, 125.452, 125.381, 125.425, 125.381, 125.367, 125.419, 125.442, 125.408, 125.364, 125.301, 125.26, 125.224, 125.159, 125.217, 125.158, 125.231, 125.173, 125.111, 125.198, 125.168, 125.09, 125.008, 124.861, 124.793, 124.736, 124.726, 124.796, 124.831, 124.917, 124.846, 124.799, 124.724, 124.73, 124.701, 124.861, 124.78, 124.876, 124.877, 124.838, 124.752, 124.586, 124.476, 124.447, 124.384, 124.441, 124.442, 124.446, 124.55, 124.491, 124.557, 124.566, 124.508, 124.589, 124.496, 124.495, 124.526, 124.503, 124.489, 124.399, 124.429, 124.452, 124.42, 124.544, 124.641, 124.572, 124.766, 124.717, 124.598, 124.594, 124.583, 124.607, 124.621, 124.679, 124.584, 124.608, 124.695, 124.759, 124.771, 124.706, 124.613, 124.726, 124.733, 124.67, 124.708, 124.761, 124.902, 124.871, 124.826, 124.788, 124.676, 124.683, 124.71, 124.857, 124.743, 124.783, 124.657, 124.687, 124.718, 124.629, 124.711, 124.673, 124.812, 124.882, 124.906, 124.884, 125.003, 125.055, 125.074, 124.971, 124.982, 124.977, 124.911, 124.929, 124.948, 124.92, 124.883, 124.833, 124.855, 124.923, 124.924, 124.888, 124.802, 124.874, 124.918, 125.089, 124.968, 125.042, 125.041, 125.109, 125.02, 125.072, 125.029, 124.979, 124.908, 124.92, 124.959, 125.054, 125.047, 125.044, 124.999, 125.044, 125.037, 125.064, 125.063, 125.071, 125.044, 125.1, 124.922, 125.031, 124.912, 124.868, 124.803, 124.823, 124.89, 125.039, 125.039, 125.0, 125.094, 125.174, 125.079, 125.041, 125.223, 125.15, 125.158, 125.296, 125.194, 125.35, 125.469, 125.454, 125.408, 125.363, 125.427, 125.371, 125.303, 125.245, 125.137, 125.076, 125.29, 125.231, 125.26, 125.26, 125.149, 125.088, 125.177, 125.279, 125.221, 125.197, 125.24, 125.18, 125.185, 125.15, 125.288, 125.274, 125.27, 125.301, 125.302, 125.273, 125.317, 125.336, 125.218, 125.025, 125.075, 124.97, 125.004, 125.035, 125.107, 125.078, 125.083, 124.964, 124.951, 124.995, 124.968, 124.989, 124.958, 124.872, 124.965, 124.925, 124.834, 124.88, 124.85, 124.832, 124.935, 124.856, 124.928, 124.872, 124.774, 124.754, 124.674, 124.611, 124.574, 124.595, 124.523, 124.542, 124.568, 124.571, 124.547, 124.631, 124.674, 124.676, 124.791, 124.787, 124.707, 124.652, 124.549, 124.665, 124.615, 124.705, 124.623, 124.706, 124.586, 124.696, 124.732, 124.691, 124.653, 124.793, 124.743, 124.801, 124.657, 124.683, 124.727, 124.698, 124.658, 124.626, 124.612, 124.699, 124.84, 124.818, 124.809, 124.687, 124.541, 124.482, 124.512, 124.435, 124.428, 124.523, 124.448, 124.341, 124.337, 124.388, 124.262, 124.315, 124.339, 124.292, 124.304, 124.359, 124.317, 124.252, 124.375, 124.332, 124.426, 124.531, 124.656, 124.689, 124.612, 124.536, 124.576, 124.63, 124.682, 124.707, 124.684, 124.759, 124.719, 124.793, 124.845, 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