# Only cancer types with minimum 2000 mutations for SBS signatures with average probability at least 0.75 are considered. signature cancer_type processive_group_length number_of_processive_groups log10_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_number_of_processive_groups SBS36 Panc-Endocrine 2 946 6.852 0.48 824.0 955.0 876.49 26.723 0.005008709613981395 0.006935136388589625 2.159 [877, 850, 893, 834, 856, 859, 895, 836, 914, 907, 912, 873, 887, 835, 849, 866, 889, 933, 852, 907, 888, 857, 848, 838, 895, 834, 846, 883, 889, 893, 920, 891, 890, 877, 865, 881, 877, 863, 882, 860, 861, 891, 853, 838, 850, 884, 868, 882, 897, 899, 844, 955, 884, 914, 868, 894, 921, 877, 827, 824, 883, 852, 862, 880, 841, 879, 906, 907, 884, 874, 894, 850, 863, 936, 875, 877, 872, 837, 877, 903, 844, 882, 883, 876, 854, 902, 831, 916, 933, 908, 876, 893, 883, 902, 844, 836, 880, 867, 872, 883] SBS36 Panc-Endocrine 3 34 3.526 0.247 17.0 41.0 28.83 4.958 0.15094305340724185 0.18113166408869025 0.742 [33, 33, 28, 26, 28, 27, 32, 30, 30, 33, 24, 26, 22, 36, 33, 31, 17, 24, 25, 39, 33, 26, 25, 31, 29, 20, 37, 32, 26, 31, 25, 30, 17, 21, 37, 29, 26, 30, 23, 26, 33, 31, 27, 36, 36, 27, 34, 21, 32, 25, 23, 23, 33, 32, 24, 18, 25, 35, 19, 30, 31, 29, 25, 32, 25, 29, 30, 26, 32, 24, 26, 27, 32, 28, 29, 29, 34, 36, 23, 29, 26, 27, 31, 29, 31, 31, 34, 27, 29, 36, 33, 32, 29, 23, 41, 36, 40, 26, 29, 22] SBS36 Panc-Endocrine 4 3 1.099 0.077 1.0 5.0 1.743 0.951 0.09637043196086786 0.1239048410925444 0.907 [5, 2, 2, 4, 2, 1, 2, 1, 3, 1, 1, 2, 2, 2, 1, 2, 2, 2, 1, 1, 2, 1, 1, 1, 3, 1, 2, 2, 1, 1, 1, 2, 3, 3, 1, 2, 1, 1, 1, 1, 1, 2, 1, 1, 1, 1, 2, 2, 1, 4, 3, 3, 1, 1, 1, 1, 1, 2, 2, 1, 2, 1, 1, 2, 1, 3, 5, 1, 2, 2] SBS36 Panc-Endocrine 5 1 0.0 0.0 1.0 1.0 1.0 0.0 inf [1, 1, 1, 1, 1] signature cancer_type processive_group_length avg_number_of_processive_groups log10_avg_number_of_processive_groups radius min_sims max_sims mean_sims std_sims pvalue qvalue minus_log10_qvalue expected_avg_number_of_processive_groups SBS36 ACROSS_ALL_CANCER_TYPES 2 946.0 2.976 0.48 824.0 955.0 876.49 26.723 0.005008709613981395 0.015026128841944186 1.823 [877.0, 850.0, 893.0, 834.0, 856.0, 859.0, 895.0, 836.0, 914.0, 907.0, 912.0, 873.0, 887.0, 835.0, 849.0, 866.0, 889.0, 933.0, 852.0, 907.0, 888.0, 857.0, 848.0, 838.0, 895.0, 834.0, 846.0, 883.0, 889.0, 893.0, 920.0, 891.0, 890.0, 877.0, 865.0, 881.0, 877.0, 863.0, 882.0, 860.0, 861.0, 891.0, 853.0, 838.0, 850.0, 884.0, 868.0, 882.0, 897.0, 899.0, 844.0, 955.0, 884.0, 914.0, 868.0, 894.0, 921.0, 877.0, 827.0, 824.0, 883.0, 852.0, 862.0, 880.0, 841.0, 879.0, 906.0, 907.0, 884.0, 874.0, 894.0, 850.0, 863.0, 936.0, 875.0, 877.0, 872.0, 837.0, 877.0, 903.0, 844.0, 882.0, 883.0, 876.0, 854.0, 902.0, 831.0, 916.0, 933.0, 908.0, 876.0, 893.0, 883.0, 902.0, 844.0, 836.0, 880.0, 867.0, 872.0, 883.0] SBS36 ACROSS_ALL_CANCER_TYPES 3 34.0 1.531 0.247 17.0 41.0 28.83 4.958 0.15094305340724185 0.15094305340724185 0.821 [33.0, 33.0, 28.0, 26.0, 28.0, 27.0, 32.0, 30.0, 30.0, 33.0, 24.0, 26.0, 22.0, 36.0, 33.0, 31.0, 17.0, 24.0, 25.0, 39.0, 33.0, 26.0, 25.0, 31.0, 29.0, 20.0, 37.0, 32.0, 26.0, 31.0, 25.0, 30.0, 17.0, 21.0, 37.0, 29.0, 26.0, 30.0, 23.0, 26.0, 33.0, 31.0, 27.0, 36.0, 36.0, 27.0, 34.0, 21.0, 32.0, 25.0, 23.0, 23.0, 33.0, 32.0, 24.0, 18.0, 25.0, 35.0, 19.0, 30.0, 31.0, 29.0, 25.0, 32.0, 25.0, 29.0, 30.0, 26.0, 32.0, 24.0, 26.0, 27.0, 32.0, 28.0, 29.0, 29.0, 34.0, 36.0, 23.0, 29.0, 26.0, 27.0, 31.0, 29.0, 31.0, 31.0, 34.0, 27.0, 29.0, 36.0, 33.0, 32.0, 29.0, 23.0, 41.0, 36.0, 40.0, 26.0, 29.0, 22.0] SBS36 ACROSS_ALL_CANCER_TYPES 4 3.0 0.477 0.077 1.0 5.0 1.743 0.951 0.09637043196086786 0.1445556479413018 0.84 [5.0, 2.0, 2.0, 4.0, 2.0, 1.0, 2.0, 1.0, 3.0, 1.0, 1.0, 2.0, 2.0, 2.0, 1.0, 2.0, 2.0, 2.0, 1.0, 1.0, 2.0, 1.0, 1.0, 1.0, 3.0, 1.0, 2.0, 2.0, 1.0, 1.0, 1.0, 2.0, 3.0, 3.0, 1.0, 2.0, 1.0, 1.0, 1.0, 1.0, 1.0, 2.0, 1.0, 1.0, 1.0, 1.0, 2.0, 2.0, 1.0, 4.0, 3.0, 3.0, 1.0, 1.0, 1.0, 1.0, 1.0, 2.0, 2.0, 1.0, 2.0, 1.0, 1.0, 2.0, 1.0, 3.0, 5.0, 1.0, 2.0, 2.0] SBS36 ACROSS_ALL_CANCER_TYPES 5 1.0 0.0 0.0 1.0 1.0 1.0 0.0 inf [1.0, 1.0, 1.0, 1.0, 1.0]