# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. signature cancer_type dna_element encode_element_list fold_change_list avg_fold_change p_value_list combined_p_value q_value SBS30 Bone-Osteosarc H2AFZ-human ['ENCFF901OMB_osteoblast_Normal_H2AFZ-human'] [1.016] 1.016 [0.787409358885869] 0.787409358885869 0.848438559406088 SBS30 Bone-Osteosarc H3K27ac-human ['ENCFF129EHI_osteoblast_Normal_H3K27ac-human'] [1.024] 1.024 [0.6439532175160181] 0.6439532175160182 0.7292941250321612 SBS30 Bone-Osteosarc H3K27me3-human ['ENCFF850AEG_osteoblast_Normal_H3K27me3-human'] [1.036] 1.036 [0.45732505443674576] 0.45732505443674576 0.5551269325763345 SBS30 Bone-Osteosarc H3K36me3-human ['ENCFF584OGM_osteoblast_Normal_H3K36me3-human'] [0.985] 0.985 [0.6370303433840221] 0.6370303433840221 0.723161369101921 SBS30 Bone-Osteosarc H3K4me1-human ['ENCFF171OLZ_osteoblast_Normal_H3K4me1-human'] [0.985] 0.985 [0.5812442400444697] 0.5812442400444697 0.6723648323939193 SBS30 Bone-Osteosarc H3K4me2-human ['ENCFF605FCR_osteoblast_Normal_H3K4me2-human'] [1.032] 1.032 [0.5386859431744007] 0.5386859431744007 0.6320911204771178 SBS30 Bone-Osteosarc H3K79me2-human ['ENCFF295PAH_osteoblast_Normal_H3K79me2-human'] [1.005] 1.005 [0.8897294035910621] 0.8897294035910621 0.9249232515792212 SBS30 Breast-Cancer H2AFZ-human ['ENCFF207FTX_mammary-epithelial-cell_Normal_H2AFZ-human'] [0.991] 0.991 [0.8557952213818271] 0.8557952213818271 0.8991473889490883 SBS30 Breast-Cancer H3K27ac-human ['ENCFF154XFN_breast-epithelium_Normal_H3K27ac-human', 'ENCFF360PVA_mammary-epithelial-cell_Normal_H3K27ac-human'] [1.056, 1.066] 1.061 [0.2760649762016014, 0.3431616491205228] 0.3179940928650845 0.41221058592004367 SBS30 Breast-Cancer H3K27me3-human ['ENCFF361SYZ_breast-epithelium_Normal_H3K27me3-human', 'ENCFF755ZGR_myoepithelial-cell-of-mammary-gland_Normal_H3K27me3-human'] [1.035, 1.104] 1.07 [0.16018763996472885, 0.02472966373245809] 0.02587245359878026 0.04572667179111924 SBS30 Breast-Cancer H3K36me3-human ['ENCFF906MJM_breast-epithelium_Normal_H3K36me3-human', 'ENCFF841TBU_myoepithelial-cell-of-mammary-gland_Normal_H3K36me3-human', 'ENCFF220HJF_luminal-epithelial-cell-of-mammary-gland_Normal_H3K36me3-human'] [1.018, 0.976, 0.979] 0.991 [0.5567579819021415, 0.26369162870282836, 0.3093029332069095] 0.40288998309391655 0.5025646505628601 SBS30 Breast-Cancer H3K4me1-human ['ENCFF609RVI_mammary-epithelial-cell_Normal_H3K4me1-human', 'ENCFF513VGQ_myoepithelial-cell-of-mammary-gland_Normal_H3K4me1-human', 'ENCFF361XJL_luminal-epithelial-cell-of-mammary-gland_Normal_H3K4me1-human'] [1.016, 0.985, 1.012] 1.005 [0.5880337927038624, 0.4848294330707682, 0.6462993229641212] 0.7594859992691241 0.8307617736104859 SBS30 Breast-Cancer H3K4me2-human ['ENCFF908LTV_mammary-epithelial-cell_Normal_H3K4me2-human'] [1.046] 1.046 [0.18479242704440968] 0.18479242704440968 0.2596296384362504 SBS30 Breast-Cancer H3K4me3-human ['ENCFF065TIH_breast-epithelium_Normal_H3K4me3-human', 'ENCFF274LUW_mammary-epithelial-cell_Normal_H3K4me3-human', 'ENCFF920PYM_myoepithelial-cell-of-mammary-gland_Normal_H3K4me3-human'] [1.054, 0.987, 1.005] 1.015 [0.30037065820803, 0.8344457627149009, 0.926749454069092] 0.818868753741945 0.8713254043560297 SBS30 Breast-Cancer H3K79me2-human ['ENCFF695AAZ_mammary-epithelial-cell_Normal_H3K79me2-human'] [1.052] 1.052 [0.2181470825129207] 0.21814708251292067 0.29979597263684693 SBS30 Breast-Cancer H3K9me3-human ['ENCFF007JDR_breast-epithelium_Normal_H3K9me3-human', 'ENCFF851QJD_mammary-epithelial-cell_Normal_H3K9me3-human'] [0.962, 0.992] 0.977 [0.2629157286967262, 0.7676967939913406] 0.5248398091767187 0.6188722642320436 SBS30 ESCC H3K27ac-human ['ENCFF683MJC_esophagus-squamous-epithelium_Normal_H3K27ac-human'] [0.994] 0.994 [0.9207320195397326] 0.9207320195397326 0.9474397522719001 SBS30 ESCC H3K36me3-human ['ENCFF848QKQ_esophagus-squamous-epithelium_Normal_H3K36me3-human'] [1.012] 1.012 [0.6461040510412214] 0.6461040510412213 0.7306517075877295 SBS30 ESCC H3K4me1-human ['ENCFF353HXQ_esophagus-squamous-epithelium_Normal_H3K4me1-human'] [1.008] 1.008 [0.7813559032472864] 0.7813559032472865 0.8447626375767368