#Only high confidence data is provided, i.e., samples with >0.90 reconstruction accuracy and at least 10 mutations attributed to the specific SBS signature.
Study	Cancer.Types	Scale	Sample.Names	Sample.Accuracy	SBS22.Mutations
PCAWG-WGS	Biliary-AdenoCA	genome	SP99345	0.972	643
PCAWG-WGS	Kidney-RCC	genome	SP103507	0.96	11802
PCAWG-WGS	Kidney-RCC	genome	SP103057	0.987	5615
PCAWG-WGS	Kidney-RCC	genome	SP102957	0.993	29716
PCAWG-WGS	Kidney-RCC	genome	SP103673	0.977	1887
PCAWG-WGS	Kidney-RCC	genome	SP103547	0.984	1078
PCAWG-WGS	Kidney-RCC	genome	SP102973	0.958	11101
PCAWG-WGS	Kidney-RCC	genome	SP103535	0.987	17394
PCAWG-WGS	Liver-HCC	genome	SP50177	0.957	1711
PCAWG-WGS	Liver-HCC	genome	SP97775	0.958	7429
PCAWG-WGS	Liver-HCC	genome	SP49247	0.957	2188
PCAWG-WGS	Liver-HCC	genome	SP49175	0.94	2203
PCAWG-WGS	Liver-HCC	genome	SP106631	0.968	2581
PCAWG-WGS	Liver-HCC	genome	SP98289	0.98	18357
PCAWG-WGS	Liver-HCC	genome	SP98090	0.933	9527
PCAWG-WGS	Liver-HCC	genome	SP99279	0.974	1170
PCAWG-WGS	Liver-HCC	genome	SP98973	0.963	4228
PCAWG-WGS	Liver-HCC	genome	SP50101	0.957	565
PCAWG-WGS	Liver-HCC	genome	SP112290	0.967	1071
PCAWG-WGS	Liver-HCC	genome	SP99053	0.962	1590
PCAWG-WGS	Liver-HCC	genome	SP50109	0.972	1480
PCAWG-WGS	Liver-HCC	genome	SP50113	0.983	2046
PCAWG-WGS	Liver-HCC	genome	SP99217	0.944	427
PCAWG-WGS	Liver-HCC	genome	SP50169	0.975	2288
PCAWG-WGS	Liver-HCC	genome	SP99257	0.979	1032
nonPCAWG-WGS	Biliary-AdenoCA	genome	CCA_SG_10	0.97	862
nonPCAWG-WGS	Biliary-AdenoCA	genome	CCA_SG_19	0.982	1251
nonPCAWG-WGS	Biliary-AdenoCA	genome	CCA_SG_9	0.994	4127
nonPCAWG-WGS	Kidney-RCC	genome	ccRCC-85	0.984	1369
nonPCAWG-WGS	Kidney-RCC	genome	C0055T	0.976	1001
nonPCAWG-WGS	Kidney-RCC	genome	C0058T	0.97	6247
nonPCAWG-WGS	Kidney-RCC	genome	C0069T	0.954	1203
nonPCAWG-WGS	Kidney-RCC	genome	C0072T	0.99	3047
nonPCAWG-WGS	Kidney-RCC	genome	C0074T	0.987	4822
nonPCAWG-WGS	Liver-HCC	genome	Sample067	0.979	1306
nonPCAWG-WGS	Liver-HCC	genome	Sample084	0.971	2188
nonPCAWG-WGS	Liver-HCC	genome	mod_sample114	0.937	290
nonPCAWG-WGS	Liver-HCC	genome	mod_sample115	0.963	760
nonPCAWG-WGS	Liver-HCC	genome	mod_sample122	0.963	1072
nonPCAWG-WGS	Liver-HCC	genome	mod_sample145	0.96	1121
nonPCAWG-WGS	Liver-HCC	genome	mod_sample41	0.992	47033
nonPCAWG-WGS	Liver-HCC	genome	mod_sample43	0.944	844
nonPCAWG-WGS	Liver-HCC	genome	mod_sample53	0.971	984
nonPCAWG-WGS	Liver-HCC	genome	mod_sample81	0.974	2491
nonPCAWG-WGS	Liver-HCC	genome	sample101	0.917	299
nonPCAWG-WGS	Liver-HCC	genome	sample108	0.953	377
nonPCAWG-WGS	Liver-HCC	genome	sample14	0.948	534
nonPCAWG-WGS	Liver-HCC	genome	sample177	0.953	1246
nonPCAWG-WGS	Liver-HCC	genome	sample198	0.966	677
nonPCAWG-WGS	Liver-HCC	genome	sample260	0.971	508
nonPCAWG-WGS	Liver-HCC	genome	sample261	0.951	961
nonPCAWG-WGS	Liver-HCC	genome	sample267	0.968	1537
nonPCAWG-WGS	Liver-HCC	genome	sample30	0.961	292
nonPCAWG-WGS	Liver-HCC	genome	sample45	0.933	355
nonPCAWG-WGS	Liver-HCC	genome	sample64	0.961	234
nonPCAWG-WGS	Liver-HCC	genome	sample79	0.965	893
TCGA-WES	Liver-HCC	exome	TCGA-CC-A5UD-01A-11D-A28X-10	0.936	177
TCGA-WES	Liver-HCC	exome	TCGA-DD-AAC8-01A-11D-A40R-10	0.974	597
TCGA-WES	Liver-HCC	exome	TCGA-DD-AACI-01A-11D-A40R-10	0.928	197
TCGA-WES	Liver-HCC	exome	TCGA-DD-AACL-01A-11D-A40R-10	0.976	369
TCGA-WES	Liver-HCC	exome	TCGA-DD-AACQ-01A-11D-A40R-10	0.971	198
TCGA-WES	Liver-HCC	exome	TCGA-DD-AACT-01A-11D-A40R-10	0.922	129
TCGA-WES	Liver-HCC	exome	TCGA-DD-AADF-01A-11D-A40R-10	0.954	151
TCGA-WES	Liver-HCC	exome	TCGA-G3-A7M5-01A-11D-A33Q-10	0.943	120
TCGA-WES	Bladder-TCC	exome	TCGA-E7-A8O8-01A-11D-A364-08	0.916	35
nonPCAWG-WES	Bladder-TCC	exome	B23-Tumor	0.953	101
nonPCAWG-WES	Bladder-TCC	exome	B89-12-Tumor	0.938	107
nonPCAWG-WES	Eso-SCC	exome	ESCC_BICR_036T	0.939	77
nonPCAWG-WES	Eso-SCC	exome	389	0.919	54
nonPCAWG-WES	Liver-HCC	exome	HCC16T	0.955	235
nonPCAWG-WES	Liver-HCC	exome	Patient3	0.928	126
nonPCAWG-WES	Liver-HCC	exome	3101B7_041_T	0.906	103
nonPCAWG-WES	Liver-HCC	exome	CDGLIV0707A0251_T	0.966	152
nonPCAWG-WES	Liver-HCC	exome	P48	0.924	79