# Only cancer types with minimum 2000 mutations for SBS signatures with average probability at least 0.75 are considered.
signature	cancer_type	processive_group_length	number_of_processive_groups	log10_number_of_processive_groups	radius	min_sims	max_sims	mean_sims	std_sims	pvalue	qvalue	minus_log10_qvalue	expected_number_of_processive_groups
SBS22	Kidney-RCC	2	3593	8.187	0.48	2037.0	2264.0	2157.72	39.651	1.4442357657612604e-281	3.7550129909792767e-281	280.425	[2118, 2129, 2116, 2264, 2163, 2174, 2113, 2189, 2149, 2139, 2153, 2152, 2150, 2186, 2227, 2146, 2104, 2173, 2157, 2166, 2181, 2230, 2151, 2168, 2162, 2169, 2186, 2188, 2198, 2169, 2232, 2118, 2115, 2192, 2199, 2131, 2252, 2129, 2148, 2103, 2186, 2196, 2156, 2144, 2154, 2152, 2150, 2168, 2122, 2081, 2204, 2149, 2180, 2110, 2104, 2140, 2146, 2184, 2177, 2194, 2150, 2156, 2188, 2166, 2153, 2182, 2228, 2060, 2189, 2178, 2178, 2210, 2189, 2147, 2205, 2113, 2101, 2205, 2210, 2180, 2037, 2101, 2153, 2119, 2115, 2142, 2105, 2199, 2130, 2168, 2198, 2181, 2110, 2110, 2136, 2174, 2159, 2127, 2133, 2101]
SBS22	Kidney-RCC	3	242	5.489	0.322	60.0	100.0	76.44	7.887	3.1256733185545093e-96	6.772292190201438e-96	95.169	[73, 92, 69, 85, 80, 77, 77, 88, 83, 74, 82, 69, 83, 81, 68, 74, 85, 77, 73, 77, 74, 82, 63, 78, 68, 91, 75, 84, 74, 68, 80, 78, 88, 85, 66, 73, 73, 82, 73, 60, 80, 71, 78, 75, 67, 65, 73, 69, 76, 72, 71, 75, 74, 79, 77, 64, 71, 68, 78, 83, 61, 67, 85, 72, 87, 87, 62, 100, 81, 69, 84, 61, 80, 74, 79, 82, 60, 69, 76, 80, 78, 85, 74, 89, 81, 80, 83, 65, 88, 67, 78, 88, 79, 89, 76, 72, 68, 85, 75, 80]
SBS22	Kidney-RCC	4	14	2.639	0.155	1.0	8.0	3.124	1.372	2.1196141265658978e-15	3.4443729556695834e-15	14.463	[4, 2, 2, 4, 3, 5, 4, 5, 2, 3, 6, 4, 5, 1, 4, 3, 2, 5, 2, 5, 5, 4, 4, 4, 4, 4, 3, 1, 1, 5, 7, 3, 4, 5, 2, 2, 8, 2, 3, 4, 4, 1, 5, 3, 2, 5, 2, 2, 2, 1, 3, 2, 2, 3, 1, 2, 2, 3, 2, 3, 1, 3, 3, 2, 2, 3, 2, 3, 5, 2, 4, 4, 4, 3, 3, 3, 1, 3, 3, 3, 2, 4, 2, 3, 3, 1, 3, 4, 2, 4, 3, 4, 1, 2, 4, 3, 5]
SBS22	Kidney-RCC	5	1	0.0	0.0	1.0	2.0	1.167	0.373	0.6660209987883802	0.7215227486874118	0.142	[1, 1, 1, 1, 1, 1, 2, 1, 1, 1, 2, 1, 1, 1, 1, 1, 1, 2, 1, 1, 1, 1, 1, 2]
SBS22	Biliary-AdenoCA	2	68	1.833	0.48	18.0	48.0	30.06	5.268	5.02854919796194e-13	1.047614416242071e-12	11.98	[34, 24, 48, 31, 32, 19, 27, 32, 26, 36, 22, 34, 35, 34, 18, 37, 32, 30, 30, 29, 34, 33, 22, 31, 25, 31, 23, 28, 36, 31, 23, 38, 23, 30, 28, 30, 28, 34, 28, 36, 32, 29, 25, 25, 25, 31, 30, 30, 27, 23, 38, 32, 30, 28, 28, 32, 32, 24, 33, 28, 26, 31, 40, 29, 28, 27, 42, 24, 30, 28, 28, 30, 29, 26, 21, 24, 33, 27, 35, 36, 39, 44, 33, 29, 26, 30, 35, 34, 32, 22, 30, 30, 30, 20, 37, 34, 27, 34, 26, 36]
SBS22	Biliary-AdenoCA	3	5	0.699	0.183	1.0	1.0	1.0	0.0	5.02854919796194e-13	1.047614416242071e-12	11.98	[1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1]
SBS22	ESCC	2	6	1.792	0.48	1.0	12.0	4.505	2.105	0.2410306407972177	0.2582471151398761	0.588	[6, 2, 7, 2, 7, 9, 4, 5, 3, 6, 5, 8, 5, 7, 5, 4, 3, 1, 2, 1, 7, 3, 6, 5, 4, 4, 1, 5, 6, 3, 2, 3, 3, 6, 4, 3, 2, 6, 7, 6, 4, 6, 3, 5, 1, 2, 5, 4, 5, 2, 2, 3, 6, 7, 4, 6, 6, 4, 5, 3, 4, 2, 4, 3, 5, 3, 7, 6, 2, 5, 4, 5, 7, 3, 2, 7, 5, 6, 12, 1, 5, 3, 4, 2, 7, 3, 4, 2, 7, 2, 4, 10, 7, 3, 5, 7, 6, 8, 3]
SBS22	Liver-HCC	2	4681	8.451	0.48	3415.0	3681.0	3536.15	53.493	6.046661153677761e-100	1.8744649576401053e-99	98.727	[3495, 3572, 3531, 3559, 3547, 3467, 3611, 3436, 3591, 3534, 3681, 3564, 3443, 3602, 3566, 3530, 3604, 3537, 3551, 3566, 3512, 3582, 3451, 3567, 3550, 3557, 3477, 3505, 3500, 3531, 3548, 3556, 3546, 3428, 3541, 3607, 3588, 3497, 3482, 3489, 3542, 3543, 3547, 3523, 3561, 3478, 3498, 3450, 3499, 3568, 3526, 3501, 3554, 3566, 3566, 3512, 3516, 3603, 3509, 3563, 3543, 3481, 3468, 3582, 3640, 3581, 3556, 3602, 3549, 3590, 3514, 3447, 3563, 3560, 3599, 3460, 3424, 3581, 3539, 3595, 3510, 3442, 3490, 3546, 3592, 3481, 3578, 3415, 3614, 3496, 3554, 3632, 3632, 3535, 3569, 3469, 3535, 3545, 3557, 3423]
SBS22	Liver-HCC	3	438	6.082	0.345	188.0	254.0	216.61	14.824	9.054662148540356e-50	2.339121055039592e-49	48.631	[193, 238, 230, 207, 222, 248, 212, 190, 210, 194, 204, 211, 219, 215, 206, 228, 227, 218, 214, 210, 208, 217, 239, 215, 203, 219, 226, 190, 218, 240, 220, 221, 242, 230, 234, 199, 237, 195, 234, 231, 227, 243, 222, 194, 228, 241, 216, 221, 212, 240, 206, 212, 206, 243, 219, 237, 207, 219, 207, 219, 213, 205, 231, 221, 204, 211, 222, 210, 211, 224, 254, 207, 220, 218, 214, 194, 230, 248, 219, 189, 219, 229, 206, 194, 212, 220, 195, 198, 202, 216, 188, 223, 225, 213, 201, 209, 193, 214, 224, 202]
SBS22	Liver-HCC	4	49	3.892	0.221	7.0	29.0	16.43	4.609	1.3175520993296836e-12	2.4025950046600115e-12	11.619	[10, 17, 20, 27, 22, 29, 20, 16, 12, 12, 16, 19, 14, 12, 16, 18, 17, 14, 16, 16, 9, 15, 18, 24, 13, 15, 21, 16, 17, 21, 23, 22, 13, 15, 16, 17, 15, 11, 11, 23, 14, 14, 17, 12, 12, 29, 20, 16, 16, 16, 16, 19, 7, 9, 15, 16, 11, 23, 25, 22, 11, 12, 14, 11, 14, 25, 20, 19, 9, 14, 14, 19, 12, 12, 13, 17, 28, 9, 14, 12, 14, 18, 13, 11, 16, 17, 14, 18, 16, 15, 21, 14, 17, 23, 15, 19, 18, 26, 16, 16]
SBS22	Liver-HCC	5	4	1.386	0.079	1.0	5.0	1.806	0.937	0.010485214490241285	0.013543402049894994	1.868	[1, 2, 2, 1, 2, 2, 1, 1, 1, 1, 1, 3, 3, 2, 1, 1, 4, 1, 1, 3, 4, 1, 2, 1, 2, 1, 4, 1, 3, 5, 1, 2, 3, 2, 3, 2, 2, 2, 1, 2, 1, 1, 2, 1, 2, 1, 2, 3, 1, 1, 1, 3, 2, 2, 2, 1, 2, 1, 1, 2, 1, 2, 1, 1, 3, 3, 1, 2, 1, 1, 1, 3]

signature	cancer_type	processive_group_length	avg_number_of_processive_groups	log10_avg_number_of_processive_groups	radius	min_sims	max_sims	mean_sims	std_sims	pvalue	qvalue	minus_log10_qvalue	expected_avg_number_of_processive_groups
SBS22	ACROSS_ALL_CANCER_TYPES	2	2087.0	3.32	0.48	1390.75	1467.5	1432.109	16.536	0.0	0.0	inf	[1413.25, 1431.75, 1425.5, 1464.0, 1437.25, 1417.25, 1438.75, 1415.5, 1442.25, 1428.75, 1465.25, 1439.5, 1408.25, 1457.25, 1454.0, 1429.25, 1435.75, 1435.25, 1435.0, 1440.5, 1433.5, 1462.0, 1407.5, 1442.75, 1435.25, 1440.25, 1421.75, 1431.5, 1435.0, 1433.5, 1451.25, 1428.75, 1421.75, 1414.0, 1443.0, 1442.75, 1467.5, 1416.5, 1416.25, 1408.5, 1441.0, 1443.5, 1432.75, 1424.25, 1435.25, 1415.75, 1420.75, 1413.0, 1413.25, 1418.5, 1442.5, 1421.25, 1442.5, 1427.75, 1425.5, 1422.5, 1425.0, 1453.75, 1431.0, 1447.0, 1430.75, 1417.5, 1425.0, 1445.0, 1456.5, 1448.25, 1458.25, 1423.0, 1442.5, 1450.25, 1431.0, 1423.0, 1447.0, 1434.0, 1456.75, 1401.0, 1390.75, 1454.75, 1449.0, 1453.0, 1397.75, 1397.5, 1420.0, 1424.0, 1435.0, 1414.0, 1430.5, 1412.5, 1445.75, 1422.0, 1446.5, 1463.25, 1444.75, 1417.0, 1436.75, 1421.0, 1431.75, 1428.5, 1429.75, 1391.126]
SBS22	ACROSS_ALL_CANCER_TYPES	3	228.333	2.359	0.341	87.333	113.0	98.017	5.22	3.422894258584504e-135	6.845788517169008e-135	134.165	[89.0, 110.333, 100.0, 97.667, 101.0, 108.667, 96.667, 93.0, 98.0, 89.667, 95.667, 93.667, 101.0, 99.0, 91.667, 101.0, 104.333, 98.667, 96.0, 96.0, 94.333, 100.0, 101.0, 98.0, 90.667, 103.667, 100.667, 91.667, 97.667, 103.0, 100.333, 100.0, 110.333, 105.333, 100.333, 91.0, 103.667, 92.667, 102.667, 97.333, 102.667, 105.0, 100.333, 90.0, 98.667, 102.333, 96.667, 97.0, 96.333, 104.333, 92.667, 96.0, 93.667, 107.667, 99.0, 100.667, 93.0, 96.0, 95.333, 101.0, 91.667, 91.0, 105.667, 98.0, 97.333, 99.667, 95.0, 103.667, 97.667, 98.0, 113.0, 89.667, 100.333, 97.667, 98.0, 92.333, 97.0, 106.0, 98.667, 90.0, 99.333, 105.0, 93.667, 94.667, 98.0, 100.333, 93.0, 88.0, 97.0, 94.667, 89.0, 104.0, 101.667, 101.0, 92.667, 94.0, 87.333, 100.0, 100.0, 94.333]
SBS22	ACROSS_ALL_CANCER_TYPES	4	31.5	1.498	0.217	4.5	17.0	9.777	2.469	1.520066852257897e-18	2.0267558030105294e-18	17.693	[7.0, 9.5, 11.0, 15.5, 12.5, 17.0, 12.0, 10.5, 7.0, 7.5, 11.0, 11.5, 9.5, 6.5, 10.0, 10.5, 9.5, 9.5, 9.0, 10.5, 7.0, 9.5, 11.0, 14.0, 8.5, 9.5, 12.0, 8.5, 9.0, 13.0, 15.0, 12.5, 8.5, 10.0, 9.0, 9.5, 11.5, 6.5, 7.0, 13.5, 9.0, 7.5, 11.0, 7.5, 7.0, 17.0, 11.0, 9.0, 9.0, 8.5, 9.5, 10.5, 4.5, 6.0, 8.0, 9.0, 6.5, 13.0, 13.5, 12.5, 6.0, 7.5, 8.5, 6.5, 8.0, 14.0, 11.0, 11.0, 7.0, 8.0, 9.0, 11.5, 8.0, 7.5, 8.0, 10.0, 14.5, 6.0, 8.5, 7.5, 8.0, 11.0, 7.5, 7.0, 9.5, 9.0, 8.5, 11.0, 9.0, 9.5, 12.0, 9.0, 9.0, 12.5, 9.5, 11.0, 11.5, 14.562, 9.562, 9.562]
SBS22	ACROSS_ALL_CANCER_TYPES	5	2.5	0.398	0.058	1.0	3.083	1.486	0.389	0.00495110383091149	0.00495110383091149	2.305	[1.0, 1.5, 1.5, 1.0, 1.5, 1.5, 1.5, 1.0, 1.0, 1.0, 1.5, 2.0, 2.0, 1.5, 1.0, 1.0, 2.5, 1.5, 1.0, 2.0, 2.5, 1.0, 1.5, 1.5, 1.583, 1.083, 2.583, 1.083, 2.083, 3.083, 1.083, 1.583, 2.083, 1.583, 2.083, 1.583, 1.583, 1.583, 1.083, 1.583, 1.083, 1.083, 1.583, 1.083, 1.583, 1.083, 1.583, 2.083, 1.083, 1.083, 1.083, 2.083, 1.583, 1.583, 1.583, 1.083, 1.583, 1.083, 1.083, 1.583, 1.083, 1.583, 1.083, 1.083, 2.083, 2.083, 1.083, 1.583, 1.083, 1.083, 1.083, 2.083, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486, 1.486]