# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
# For real mutations on genic (transcribed:T, untranscribed:U and bitranscribed:B) and intergenic (nontranscribed:N) regions averaged across cancer types.
MutationType	Across_All_Cancer_Types
T:A[C>A]A	38.857
U:A[C>A]A	20.0
B:A[C>A]A	0.0
N:A[C>A]A	129.857
T:A[C>A]C	0.286
U:A[C>A]C	0.143
B:A[C>A]C	0.0
N:A[C>A]C	2.0
T:A[C>A]G	2.571
U:A[C>A]G	2.143
B:A[C>A]G	0.0
N:A[C>A]G	10.143
T:A[C>A]T	9.857
U:A[C>A]T	6.714
B:A[C>A]T	0.0
N:A[C>A]T	45.0
T:A[C>G]A	6.571
U:A[C>G]A	3.286
B:A[C>G]A	0.0
N:A[C>G]A	23.714
T:A[C>G]C	0.143
U:A[C>G]C	0.143
B:A[C>G]C	0.0
N:A[C>G]C	1.857
T:A[C>G]G	0.429
U:A[C>G]G	0.0
B:A[C>G]G	0.0
N:A[C>G]G	1.714
T:A[C>G]T	0.0
U:A[C>G]T	0.0
B:A[C>G]T	0.0
N:A[C>G]T	0.286
T:A[C>T]A	5.571
U:A[C>T]A	3.0
B:A[C>T]A	0.0
N:A[C>T]A	16.857
T:A[C>T]C	0.286
U:A[C>T]C	0.143
B:A[C>T]C	0.0
N:A[C>T]C	1.286
T:A[C>T]G	5.714
U:A[C>T]G	4.714
B:A[C>T]G	0.0
N:A[C>T]G	22.714
T:A[C>T]T	0.857
U:A[C>T]T	0.429
B:A[C>T]T	0.0
N:A[C>T]T	6.0
T:A[T>A]A	502.286
U:A[T>A]A	254.0
B:A[T>A]A	1.143
N:A[T>A]A	1630.714
T:A[T>A]C	62.429
U:A[T>A]C	35.857
B:A[T>A]C	0.143
N:A[T>A]C	198.143
T:A[T>A]G	440.286
U:A[T>A]G	243.429
B:A[T>A]G	2.143
N:A[T>A]G	1397.429
T:A[T>A]T	62.143
U:A[T>A]T	38.0
B:A[T>A]T	0.286
N:A[T>A]T	206.143
T:A[T>C]A	207.429
U:A[T>C]A	92.857
B:A[T>C]A	1.0
N:A[T>C]A	519.857
T:A[T>C]C	3.429
U:A[T>C]C	1.857
B:A[T>C]C	0.0
N:A[T>C]C	9.286
T:A[T>C]G	46.0
U:A[T>C]G	23.429
B:A[T>C]G	0.0
N:A[T>C]G	124.143
T:A[T>C]T	3.0
U:A[T>C]T	1.429
B:A[T>C]T	0.0
N:A[T>C]T	8.286
T:A[T>G]A	21.429
U:A[T>G]A	12.714
B:A[T>G]A	0.0
N:A[T>G]A	71.714
T:A[T>G]C	0.0
U:A[T>G]C	0.0
B:A[T>G]C	0.0
N:A[T>G]C	0.571
T:A[T>G]G	9.857
U:A[T>G]G	7.857
B:A[T>G]G	0.0
N:A[T>G]G	44.0
T:A[T>G]T	0.143
U:A[T>G]T	0.143
B:A[T>G]T	0.0
N:A[T>G]T	0.286
T:C[C>A]A	17.286
U:C[C>A]A	10.571
B:C[C>A]A	0.0
N:C[C>A]A	65.857
T:C[C>A]C	33.429
U:C[C>A]C	22.571
B:C[C>A]C	0.0
N:C[C>A]C	113.571
T:C[C>A]G	0.143
U:C[C>A]G	0.0
B:C[C>A]G	0.0
N:C[C>A]G	1.286
T:C[C>A]T	0.714
U:C[C>A]T	0.286
B:C[C>A]T	0.0
N:C[C>A]T	4.0
T:C[C>G]A	3.571
U:C[C>G]A	2.286
B:C[C>G]A	0.0
N:C[C>G]A	13.286
T:C[C>G]C	1.714
U:C[C>G]C	0.857
B:C[C>G]C	0.0
N:C[C>G]C	8.143
T:C[C>G]G	0.143
U:C[C>G]G	0.143
B:C[C>G]G	0.0
N:C[C>G]G	0.571
T:C[C>G]T	0.429
U:C[C>G]T	0.571
B:C[C>G]T	0.0
N:C[C>G]T	3.857
T:C[C>T]A	5.286
U:C[C>T]A	5.857
B:C[C>T]A	0.0
N:C[C>T]A	22.143
T:C[C>T]C	12.429
U:C[C>T]C	14.857
B:C[C>T]C	0.0
N:C[C>T]C	51.143
T:C[C>T]G	0.714
U:C[C>T]G	1.429
B:C[C>T]G	0.0
N:C[C>T]G	3.714
T:C[C>T]T	6.143
U:C[C>T]T	6.286
B:C[C>T]T	0.0
N:C[C>T]T	29.429
T:C[T>A]A	876.571
U:C[T>A]A	414.429
B:C[T>A]A	5.0
N:C[T>A]A	2608.143
T:C[T>A]C	396.286
U:C[T>A]C	218.857
B:C[T>A]C	3.143
N:C[T>A]C	1148.571
T:C[T>A]G	1194.143
U:C[T>A]G	658.714
B:C[T>A]G	10.429
N:C[T>A]G	3390.286
T:C[T>A]T	400.0
U:C[T>A]T	259.857
B:C[T>A]T	3.571
N:C[T>A]T	1315.571
T:C[T>C]A	45.429
U:C[T>C]A	26.143
B:C[T>C]A	0.143
N:C[T>C]A	140.143
T:C[T>C]C	6.571
U:C[T>C]C	4.571
B:C[T>C]C	0.0
N:C[T>C]C	22.143
T:C[T>C]G	8.571
U:C[T>C]G	7.0
B:C[T>C]G	0.0
N:C[T>C]G	27.143
T:C[T>C]T	1.714
U:C[T>C]T	1.286
B:C[T>C]T	0.0
N:C[T>C]T	8.429
T:C[T>G]A	30.286
U:C[T>G]A	17.429
B:C[T>G]A	0.0
N:C[T>G]A	96.714
T:C[T>G]C	4.857
U:C[T>G]C	3.714
B:C[T>G]C	0.0
N:C[T>G]C	13.286
T:C[T>G]G	42.571
U:C[T>G]G	30.143
B:C[T>G]G	0.286
N:C[T>G]G	138.429
T:C[T>G]T	5.0
U:C[T>G]T	4.857
B:C[T>G]T	0.0
N:C[T>G]T	17.857
T:G[C>A]A	8.714
U:G[C>A]A	6.429
B:G[C>A]A	0.0
N:G[C>A]A	42.714
T:G[C>A]C	11.143
U:G[C>A]C	6.571
B:G[C>A]C	0.0
N:G[C>A]C	37.0
T:G[C>A]G	2.0
U:G[C>A]G	0.714
B:G[C>A]G	0.0
N:G[C>A]G	7.0
T:G[C>A]T	2.143
U:G[C>A]T	2.143
B:G[C>A]T	0.0
N:G[C>A]T	12.429
T:G[C>G]A	4.0
U:G[C>G]A	2.143
B:G[C>G]A	0.0
N:G[C>G]A	16.571
T:G[C>G]C	2.571
U:G[C>G]C	2.143
B:G[C>G]C	0.0
N:G[C>G]C	11.0
T:G[C>G]G	0.143
U:G[C>G]G	0.143
B:G[C>G]G	0.0
N:G[C>G]G	1.286
T:G[C>G]T	0.286
U:G[C>G]T	0.714
B:G[C>G]T	0.0
N:G[C>G]T	4.0
T:G[C>T]A	8.143
U:G[C>T]A	7.143
B:G[C>T]A	0.0
N:G[C>T]A	29.571
T:G[C>T]C	4.857
U:G[C>T]C	4.429
B:G[C>T]C	0.0
N:G[C>T]C	20.0
T:G[C>T]G	0.0
U:G[C>T]G	0.0
B:G[C>T]G	0.0
N:G[C>T]G	0.0
T:G[C>T]T	5.571
U:G[C>T]T	4.286
B:G[C>T]T	0.0
N:G[C>T]T	22.571
T:G[T>A]A	350.857
U:G[T>A]A	194.286
B:G[T>A]A	1.429
N:G[T>A]A	1138.857
T:G[T>A]C	69.0
U:G[T>A]C	44.143
B:G[T>A]C	0.0
N:G[T>A]C	222.0
T:G[T>A]G	251.857
U:G[T>A]G	165.857
B:G[T>A]G	1.286
N:G[T>A]G	802.143
T:G[T>A]T	67.0
U:G[T>A]T	46.429
B:G[T>A]T	0.286
N:G[T>A]T	238.571
T:G[T>C]A	5.0
U:G[T>C]A	3.571
B:G[T>C]A	0.0
N:G[T>C]A	19.286
T:G[T>C]C	4.429
U:G[T>C]C	3.429
B:G[T>C]C	0.0
N:G[T>C]C	19.143
T:G[T>C]G	2.143
U:G[T>C]G	1.714
B:G[T>C]G	0.0
N:G[T>C]G	9.429
T:G[T>C]T	2.857
U:G[T>C]T	2.857
B:G[T>C]T	0.0
N:G[T>C]T	14.143
T:G[T>G]A	8.0
U:G[T>G]A	5.857
B:G[T>G]A	0.0
N:G[T>G]A	31.0
T:G[T>G]C	0.286
U:G[T>G]C	0.286
B:G[T>G]C	0.0
N:G[T>G]C	2.429
T:G[T>G]G	2.143
U:G[T>G]G	2.0
B:G[T>G]G	0.0
N:G[T>G]G	8.143
T:G[T>G]T	0.0
U:G[T>G]T	0.0
B:G[T>G]T	0.0
N:G[T>G]T	0.143
T:T[C>A]A	7.0
U:T[C>A]A	5.429
B:T[C>A]A	0.0
N:T[C>A]A	28.571
T:T[C>A]C	13.857
U:T[C>A]C	8.571
B:T[C>A]C	0.0
N:T[C>A]C	52.714
T:T[C>A]G	0.0
U:T[C>A]G	0.0
B:T[C>A]G	0.0
N:T[C>A]G	0.0
T:T[C>A]T	2.429
U:T[C>A]T	1.857
B:T[C>A]T	0.0
N:T[C>A]T	10.857
T:T[C>G]A	13.286
U:T[C>G]A	11.857
B:T[C>G]A	0.143
N:T[C>G]A	52.857
T:T[C>G]C	5.571
U:T[C>G]C	5.286
B:T[C>G]C	0.0
N:T[C>G]C	21.857
T:T[C>G]G	0.286
U:T[C>G]G	0.714
B:T[C>G]G	0.0
N:T[C>G]G	2.571
T:T[C>G]T	1.286
U:T[C>G]T	2.0
B:T[C>G]T	0.0
N:T[C>G]T	7.429
T:T[C>T]A	5.857
U:T[C>T]A	7.286
B:T[C>T]A	0.0
N:T[C>T]A	26.571
T:T[C>T]C	4.857
U:T[C>T]C	4.429
B:T[C>T]C	0.0
N:T[C>T]C	19.857
T:T[C>T]G	0.0
U:T[C>T]G	0.0
B:T[C>T]G	0.0
N:T[C>T]G	0.0
T:T[C>T]T	0.0
U:T[C>T]T	0.0
B:T[C>T]T	0.0
N:T[C>T]T	0.0
T:T[T>A]A	578.0
U:T[T>A]A	336.143
B:T[T>A]A	3.286
N:T[T>A]A	1926.429
T:T[T>A]C	172.429
U:T[T>A]C	115.571
B:T[T>A]C	1.0
N:T[T>A]C	576.286
T:T[T>A]G	431.286
U:T[T>A]G	288.429
B:T[T>A]G	3.286
N:T[T>A]G	1536.0
T:T[T>A]T	196.143
U:T[T>A]T	149.143
B:T[T>A]T	1.0
N:T[T>A]T	720.571
T:T[T>C]A	43.857
U:T[T>C]A	30.0
B:T[T>C]A	0.0
N:T[T>C]A	134.714
T:T[T>C]C	0.0
U:T[T>C]C	0.0
B:T[T>C]C	0.0
N:T[T>C]C	0.0
T:T[T>C]G	5.571
U:T[T>C]G	4.857
B:T[T>C]G	0.0
N:T[T>C]G	24.286
T:T[T>C]T	0.0
U:T[T>C]T	0.0
B:T[T>C]T	0.0
N:T[T>C]T	0.0
T:T[T>G]A	23.571
U:T[T>G]A	20.0
B:T[T>G]A	0.143
N:T[T>G]A	95.286
T:T[T>G]C	2.857
U:T[T>G]C	2.143
B:T[T>G]C	0.0
N:T[T>G]C	8.286
T:T[T>G]G	22.714
U:T[T>G]G	19.0
B:T[T>G]G	0.0
N:T[T>G]G	91.714
T:T[T>G]T	1.857
U:T[T>G]T	2.429
B:T[T>G]T	0.0
N:T[T>G]T	7.571

# There must be at least 1000 mutations on the strands.
# Signature and mutation type must have at least 5% of all signature mutations on the strands.
# Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1.
cancer_type	signature	mutation_type	genic_real_count	intergenic_real_count	genic_mean_sims_count	intergenic_mean_sims_count	genic_versus_intergenic_p_value	genic_versus_intergenic_q_value	percentage_of_mutations_on_strands	signature_number_of_mutations_on_strands	significant_strand	FC_REAL	FC_SIMS	FC	fold_change_1.1	fold_change_1.2	fold_change_1.3	fold_change_1.5	fold_change_1.75	fold_change_2+	Transcribed_real_count	Transcribed_mean_sims_count	Transcribed_min_sims_count	Transcribed_max_sims_count	Transcribed_sims_count_list	UnTranscribed_real_count	UnTranscribed_mean_sims_count	UnTranscribed_min_sims_count	UnTranscribed_max_sims_count	UnTranscribed_sims_count_list	NonTranscribed_real_count	NonTranscribed_mean_sims_count	NonTranscribed_min_sims_count	NonTranscribed_max_sims_count	NonTranscribed_sims_count_list
Biliary-AdenoCA	SBS22	C>A	31.0	40.0	30.59	40.7	1.0	1.0	1.035	6863.0	Intergenic	1.29	1.331	0.97							22.0	15.81	6.0	24.0	[19.0, 15.0, 15.0, 7.0, 16.0, 17.0, 17.0, 20.0, 20.0, 20.0, 16.0, 10.0, 15.0, 13.0, 11.0, 14.0, 19.0, 16.0, 17.0, 18.0, 16.0, 13.0, 17.0, 23.0, 18.0, 19.0, 10.0, 11.0, 15.0, 15.0, 20.0, 16.0, 18.0, 17.0, 11.0, 15.0, 18.0, 17.0, 14.0, 17.0, 16.0, 10.0, 12.0, 10.0, 14.0, 15.0, 13.0, 13.0, 12.0, 20.0, 21.0, 17.0, 18.0, 18.0, 13.0, 13.0, 17.0, 13.0, 16.0, 12.0, 15.0, 14.0, 18.0, 15.0, 18.0, 17.0, 8.0, 15.0, 15.0, 13.0, 18.0, 14.0, 19.0, 18.0, 21.0, 15.0, 22.0, 19.0, 20.0, 16.0, 24.0, 16.0, 11.0, 20.0, 6.0, 18.0, 13.0, 11.0, 20.0, 19.0, 19.0, 21.0, 18.0, 15.0, 9.0, 14.0, 15.0, 11.0, 23.0, 20.0]	9.0	14.78	8.0	23.0	[16.0, 11.0, 13.0, 19.0, 10.0, 13.0, 16.0, 14.0, 14.0, 8.0, 11.0, 15.0, 17.0, 13.0, 21.0, 9.0, 11.0, 22.0, 12.0, 15.0, 14.0, 10.0, 12.0, 12.0, 12.0, 14.0, 22.0, 19.0, 11.0, 14.0, 9.0, 16.0, 14.0, 22.0, 13.0, 15.0, 12.0, 17.0, 13.0, 16.0, 17.0, 20.0, 19.0, 21.0, 15.0, 19.0, 9.0, 15.0, 11.0, 16.0, 15.0, 12.0, 11.0, 18.0, 12.0, 16.0, 14.0, 19.0, 17.0, 13.0, 14.0, 14.0, 20.0, 18.0, 14.0, 14.0, 13.0, 14.0, 10.0, 19.0, 18.0, 10.0, 17.0, 17.0, 9.0, 14.0, 13.0, 15.0, 13.0, 10.0, 12.0, 22.0, 18.0, 9.0, 14.0, 17.0, 16.0, 15.0, 12.0, 14.0, 15.0, 15.0, 9.0, 20.0, 20.0, 23.0, 17.0, 16.0, 18.0, 14.0]	40.0	40.7	33.0	51.0	[36.0, 45.0, 43.0, 45.0, 45.0, 41.0, 38.0, 37.0, 38.0, 43.0, 44.0, 46.0, 40.0, 45.0, 40.0, 48.0, 41.0, 33.0, 42.0, 39.0, 41.0, 48.0, 43.0, 36.0, 41.0, 38.0, 39.0, 41.0, 45.0, 42.0, 42.0, 40.0, 39.0, 33.0, 47.0, 42.0, 41.0, 38.0, 44.0, 39.0, 39.0, 41.0, 41.0, 40.0, 42.0, 37.0, 49.0, 43.0, 48.0, 36.0, 35.0, 42.0, 42.0, 35.0, 46.0, 42.0, 40.0, 39.0, 38.0, 46.0, 42.0, 43.0, 34.0, 38.0, 39.0, 40.0, 50.0, 43.0, 46.0, 39.0, 35.0, 47.0, 36.0, 38.0, 41.0, 42.0, 37.0, 37.0, 38.0, 45.0, 35.0, 33.0, 43.0, 42.0, 51.0, 37.0, 42.0, 45.0, 40.0, 38.0, 37.0, 35.0, 44.0, 38.0, 43.0, 34.0, 39.0, 44.0, 33.0, 38.0]
Biliary-AdenoCA	SBS22	C>G	8.0	11.0	7.63	11.42	1.0	1.0	0.277	6863.0	Intergenic	1.375	1.497	0.919							6.0	3.89	0.0	8.0	[3.0, 4.0, 2.0, 7.0, 4.0, 4.0, 5.0, 2.0, 5.0, 1.0, 5.0, 6.0, 4.0, 3.0, 8.0, 3.0, 5.0, 6.0, 6.0, 5.0, 1.0, 8.0, 5.0, 6.0, 5.0, 2.0, 4.0, 4.0, 5.0, 5.0, 1.0, 5.0, 3.0, 0.0, 2.0, 2.0, 4.0, 4.0, 6.0, 5.0, 3.0, 3.0, 4.0, 1.0, 5.0, 5.0, 7.0, 5.0, 2.0, 3.0, 3.0, 3.0, 3.0, 1.0, 6.0, 8.0, 5.0, 4.0, 3.0, 2.0, 3.0, 3.0, 6.0, 4.0, 3.0, 6.0, 2.0, 3.0, 5.0, 3.0, 6.0, 4.0, 4.0, 5.0, 3.0, 2.0, 5.0, 2.0, 4.0, 2.0, 3.0, 3.0, 4.0, 4.0, 3.0, 2.0, 5.0, 1.0, 3.0, 3.0, 2.0, 7.0, 6.0, 2.0, 3.0, 6.0, 3.0, 5.0, 4.0, 4.0]	2.0	3.74	0.0	8.0	[5.0, 6.0, 6.0, 1.0, 2.0, 7.0, 4.0, 5.0, 5.0, 2.0, 5.0, 3.0, 4.0, 3.0, 2.0, 6.0, 4.0, 3.0, 2.0, 3.0, 2.0, 5.0, 3.0, 0.0, 4.0, 5.0, 7.0, 2.0, 3.0, 5.0, 5.0, 1.0, 5.0, 2.0, 1.0, 3.0, 2.0, 3.0, 4.0, 3.0, 4.0, 3.0, 3.0, 6.0, 3.0, 3.0, 4.0, 2.0, 4.0, 1.0, 1.0, 2.0, 3.0, 5.0, 1.0, 1.0, 6.0, 3.0, 5.0, 7.0, 3.0, 6.0, 2.0, 4.0, 5.0, 6.0, 4.0, 4.0, 3.0, 5.0, 1.0, 3.0, 1.0, 4.0, 3.0, 5.0, 7.0, 6.0, 2.0, 4.0, 4.0, 3.0, 5.0, 2.0, 3.0, 4.0, 6.0, 3.0, 8.0, 5.0, 3.0, 3.0, 2.0, 6.0, 5.0, 5.0, 2.0, 4.0, 5.0, 8.0]	11.0	11.42	6.0	17.0	[11.0, 9.0, 11.0, 11.0, 13.0, 8.0, 10.0, 12.0, 9.0, 16.0, 9.0, 10.0, 11.0, 13.0, 9.0, 10.0, 10.0, 10.0, 11.0, 12.0, 16.0, 6.0, 11.0, 13.0, 10.0, 12.0, 8.0, 13.0, 12.0, 9.0, 13.0, 13.0, 11.0, 17.0, 16.0, 14.0, 13.0, 12.0, 9.0, 11.0, 12.0, 13.0, 12.0, 12.0, 11.0, 11.0, 8.0, 12.0, 13.0, 15.0, 15.0, 14.0, 13.0, 13.0, 12.0, 10.0, 8.0, 12.0, 11.0, 10.0, 13.0, 10.0, 11.0, 11.0, 11.0, 7.0, 13.0, 12.0, 11.0, 11.0, 12.0, 12.0, 14.0, 10.0, 13.0, 12.0, 7.0, 11.0, 13.0, 13.0, 12.0, 13.0, 10.0, 13.0, 13.0, 13.0, 8.0, 15.0, 9.0, 11.0, 14.0, 9.0, 11.0, 11.0, 11.0, 8.0, 14.0, 11.0, 10.0, 8.0]
Biliary-AdenoCA	SBS22	C>T	0.0	0.0	0.0	0.0	1.0	1.0	0.0	6863.0											0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]	0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]	0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]
Biliary-AdenoCA	SBS22	T>A	2303.0	4079.0	2697.91	3689.57	1.1626614493203056e-12	7.997101058288967e-12	92.991	6863.0	Intergenic	1.771	1.368	1.295	1	1	1				1479.0	1317.97	1244.0	1397.0	[1306.0, 1280.0, 1355.0, 1284.0, 1317.0, 1318.0, 1336.0, 1304.0, 1318.0, 1353.0, 1349.0, 1289.0, 1369.0, 1304.0, 1316.0, 1297.0, 1272.0, 1314.0, 1314.0, 1347.0, 1278.0, 1288.0, 1334.0, 1312.0, 1297.0, 1350.0, 1343.0, 1295.0, 1346.0, 1346.0, 1300.0, 1312.0, 1333.0, 1353.0, 1296.0, 1289.0, 1316.0, 1327.0, 1293.0, 1307.0, 1397.0, 1322.0, 1280.0, 1304.0, 1337.0, 1260.0, 1347.0, 1288.0, 1332.0, 1339.0, 1304.0, 1346.0, 1316.0, 1350.0, 1308.0, 1291.0, 1286.0, 1336.0, 1338.0, 1348.0, 1308.0, 1361.0, 1387.0, 1349.0, 1339.0, 1244.0, 1277.0, 1289.0, 1312.0, 1355.0, 1336.0, 1356.0, 1336.0, 1312.0, 1322.0, 1293.0, 1306.0, 1288.0, 1316.0, 1295.0, 1326.0, 1322.0, 1256.0, 1328.0, 1320.0, 1333.0, 1305.0, 1345.0, 1339.0, 1307.0, 1341.0, 1255.0, 1317.0, 1273.0, 1335.0, 1354.0, 1286.0, 1313.0, 1305.0, 1370.0]	824.0	1379.94	1306.0	1458.0	[1385.0, 1359.0, 1395.0, 1431.0, 1458.0, 1395.0, 1376.0, 1434.0, 1365.0, 1414.0, 1369.0, 1396.0, 1342.0, 1391.0, 1389.0, 1363.0, 1347.0, 1379.0, 1353.0, 1416.0, 1394.0, 1333.0, 1413.0, 1364.0, 1427.0, 1392.0, 1399.0, 1381.0, 1363.0, 1399.0, 1426.0, 1343.0, 1376.0, 1339.0, 1406.0, 1351.0, 1379.0, 1383.0, 1368.0, 1408.0, 1344.0, 1351.0, 1381.0, 1404.0, 1360.0, 1362.0, 1368.0, 1331.0, 1364.0, 1334.0, 1389.0, 1355.0, 1394.0, 1405.0, 1402.0, 1330.0, 1360.0, 1364.0, 1376.0, 1366.0, 1360.0, 1407.0, 1340.0, 1367.0, 1393.0, 1419.0, 1355.0, 1355.0, 1344.0, 1368.0, 1398.0, 1371.0, 1370.0, 1327.0, 1426.0, 1445.0, 1381.0, 1369.0, 1306.0, 1443.0, 1415.0, 1420.0, 1395.0, 1403.0, 1368.0, 1456.0, 1313.0, 1350.0, 1401.0, 1376.0, 1419.0, 1407.0, 1363.0, 1391.0, 1339.0, 1334.0, 1341.0, 1440.0, 1381.0, 1397.0]	4079.0	3689.57	3595.0	3773.0	[3694.0, 3736.0, 3642.0, 3674.0, 3623.0, 3673.0, 3680.0, 3641.0, 3699.0, 3626.0, 3675.0, 3711.0, 3678.0, 3690.0, 3680.0, 3720.0, 3769.0, 3691.0, 3714.0, 3628.0, 3708.0, 3763.0, 3634.0, 3709.0, 3655.0, 3651.0, 3642.0, 3718.0, 3678.0, 3642.0, 3655.0, 3741.0, 3682.0, 3700.0, 3686.0, 3746.0, 3689.0, 3684.0, 3732.0, 3682.0, 3651.0, 3712.0, 3726.0, 3682.0, 3697.0, 3773.0, 3683.0, 3773.0, 3688.0, 3714.0, 3699.0, 3692.0, 3682.0, 3635.0, 3677.0, 3762.0, 3750.0, 3691.0, 3668.0, 3673.0, 3713.0, 3628.0, 3656.0, 3671.0, 3657.0, 3723.0, 3755.0, 3736.0, 3738.0, 3660.0, 3655.0, 3651.0, 3675.0, 3745.0, 3644.0, 3650.0, 3703.0, 3725.0, 3763.0, 3656.0, 3648.0, 3642.0, 3728.0, 3657.0, 3705.0, 3595.0, 3764.0, 3689.0, 3645.0, 3708.0, 3628.0, 3727.0, 3704.0, 3718.0, 3711.0, 3702.0, 3756.0, 3636.0, 3703.0, 3618.0]
Biliary-AdenoCA	SBS22	T>C	72.0	168.0	97.46	143.61	0.02168127421096027	0.07364595126482176	3.497	6863.0	Intergenic	2.333	1.474	1.584	1	1	1	1			50.0	49.88	36.0	69.0	[49.0, 43.0, 50.0, 60.0, 61.0, 46.0, 48.0, 45.0, 49.0, 58.0, 57.0, 42.0, 56.0, 69.0, 57.0, 57.0, 48.0, 36.0, 55.0, 43.0, 51.0, 56.0, 48.0, 50.0, 46.0, 59.0, 55.0, 47.0, 38.0, 50.0, 45.0, 44.0, 65.0, 51.0, 55.0, 57.0, 42.0, 50.0, 50.0, 37.0, 47.0, 53.0, 45.0, 47.0, 43.0, 47.0, 56.0, 58.0, 54.0, 56.0, 50.0, 44.0, 44.0, 38.0, 44.0, 65.0, 50.0, 67.0, 57.0, 51.0, 57.0, 45.0, 46.0, 40.0, 55.0, 51.0, 53.0, 46.0, 42.0, 46.0, 40.0, 51.0, 44.0, 45.0, 46.0, 61.0, 51.0, 50.0, 46.0, 46.0, 55.0, 52.0, 50.0, 59.0, 43.0, 39.0, 36.0, 58.0, 47.0, 50.0, 49.0, 43.0, 49.0, 49.0, 57.0, 50.0, 54.0, 53.0, 42.0, 51.0]	22.0	47.58	32.0	62.0	[41.0, 51.0, 48.0, 44.0, 60.0, 41.0, 54.0, 43.0, 50.0, 49.0, 41.0, 50.0, 56.0, 42.0, 39.0, 52.0, 62.0, 59.0, 44.0, 46.0, 46.0, 32.0, 48.0, 42.0, 49.0, 45.0, 49.0, 37.0, 60.0, 45.0, 43.0, 49.0, 42.0, 50.0, 52.0, 45.0, 55.0, 41.0, 42.0, 43.0, 42.0, 53.0, 42.0, 53.0, 49.0, 47.0, 43.0, 43.0, 40.0, 52.0, 51.0, 49.0, 51.0, 57.0, 44.0, 42.0, 39.0, 44.0, 40.0, 54.0, 36.0, 47.0, 43.0, 50.0, 54.0, 52.0, 32.0, 56.0, 56.0, 49.0, 54.0, 62.0, 47.0, 48.0, 55.0, 52.0, 62.0, 49.0, 50.0, 46.0, 42.0, 54.0, 46.0, 48.0, 47.0, 50.0, 54.0, 52.0, 46.0, 47.0, 44.0, 41.0, 52.0, 47.0, 47.0, 52.0, 45.0, 40.0, 50.0, 32.0]	168.0	143.61	121.0	162.0	[150.0, 146.0, 144.0, 136.0, 121.0, 154.0, 140.0, 153.0, 142.0, 134.0, 144.0, 149.0, 130.0, 129.0, 145.0, 132.0, 132.0, 145.0, 141.0, 154.0, 147.0, 152.0, 146.0, 149.0, 145.0, 136.0, 139.0, 157.0, 143.0, 148.0, 153.0, 147.0, 135.0, 140.0, 135.0, 139.0, 143.0, 149.0, 149.0, 162.0, 151.0, 134.0, 153.0, 140.0, 150.0, 146.0, 143.0, 140.0, 147.0, 135.0, 140.0, 147.0, 145.0, 149.0, 152.0, 135.0, 151.0, 130.0, 144.0, 135.0, 147.0, 148.0, 153.0, 152.0, 133.0, 138.0, 156.0, 139.0, 142.0, 145.0, 147.0, 129.0, 149.0, 148.0, 141.0, 128.0, 129.0, 141.0, 144.0, 148.0, 144.0, 136.0, 146.0, 134.0, 152.0, 151.0, 151.0, 132.0, 149.0, 145.0, 148.0, 156.0, 139.0, 145.0, 138.0, 139.0, 143.0, 148.0, 148.0, 158.0]
Biliary-AdenoCA	SBS22	T>G	53.0	98.0	65.22	86.51	0.19442433963451144	0.4835179923600878	2.2	6863.0	Intergenic	1.849	1.326	1.394	1	1	1				29.0	32.03	21.0	43.0	[29.0, 28.0, 32.0, 24.0, 28.0, 33.0, 32.0, 30.0, 34.0, 35.0, 31.0, 32.0, 29.0, 37.0, 26.0, 43.0, 32.0, 33.0, 30.0, 28.0, 39.0, 33.0, 37.0, 30.0, 39.0, 41.0, 33.0, 26.0, 35.0, 26.0, 35.0, 41.0, 24.0, 28.0, 27.0, 35.0, 36.0, 29.0, 31.0, 39.0, 29.0, 32.0, 36.0, 24.0, 30.0, 35.0, 34.0, 32.0, 26.0, 34.0, 39.0, 31.0, 35.0, 23.0, 26.0, 35.0, 38.0, 35.0, 37.0, 33.0, 31.0, 29.0, 30.0, 33.0, 28.0, 26.0, 23.0, 31.0, 33.0, 21.0, 35.0, 28.0, 33.0, 35.0, 38.0, 39.0, 39.0, 31.0, 27.0, 38.0, 29.0, 33.0, 41.0, 34.0, 33.0, 27.0, 33.0, 32.0, 25.0, 31.0, 35.0, 24.0, 38.0, 27.0, 25.0, 39.0, 32.0, 38.0, 34.0, 31.0]	24.0	33.19	21.0	46.0	[40.0, 40.0, 33.0, 42.0, 35.0, 26.0, 31.0, 37.0, 38.0, 40.0, 28.0, 32.0, 27.0, 28.0, 39.0, 30.0, 34.0, 35.0, 32.0, 33.0, 27.0, 34.0, 32.0, 26.0, 39.0, 27.0, 39.0, 37.0, 30.0, 39.0, 33.0, 26.0, 31.0, 30.0, 43.0, 32.0, 30.0, 33.0, 28.0, 32.0, 34.0, 28.0, 30.0, 37.0, 25.0, 36.0, 39.0, 38.0, 37.0, 34.0, 34.0, 36.0, 26.0, 46.0, 36.0, 36.0, 41.0, 29.0, 21.0, 34.0, 35.0, 30.0, 29.0, 37.0, 38.0, 41.0, 43.0, 38.0, 22.0, 30.0, 30.0, 27.0, 31.0, 31.0, 25.0, 35.0, 32.0, 34.0, 36.0, 32.0, 30.0, 38.0, 35.0, 39.0, 26.0, 29.0, 39.0, 29.0, 35.0, 35.0, 40.0, 39.0, 24.0, 34.0, 32.0, 24.0, 33.0, 30.0, 35.0, 32.0]	98.0	86.51	74.0	100.0	[83.0, 84.0, 89.0, 86.0, 88.0, 93.0, 88.0, 84.0, 80.0, 76.0, 93.0, 87.0, 95.0, 88.0, 86.0, 80.0, 86.0, 85.0, 89.0, 90.0, 86.0, 84.0, 82.0, 98.0, 76.0, 83.0, 79.0, 88.0, 86.0, 86.0, 83.0, 86.0, 96.0, 94.0, 81.0, 85.0, 87.0, 92.0, 92.0, 80.0, 89.0, 92.0, 86.0, 90.0, 97.0, 81.0, 79.0, 81.0, 90.0, 83.0, 78.0, 86.0, 91.0, 83.0, 89.0, 81.0, 74.0, 87.0, 93.0, 84.0, 88.0, 93.0, 92.0, 83.0, 86.0, 85.0, 86.0, 82.0, 96.0, 100.0, 86.0, 96.0, 88.0, 85.0, 89.0, 77.0, 80.0, 86.0, 89.0, 83.0, 92.0, 81.0, 76.0, 79.0, 92.0, 96.0, 79.0, 91.0, 91.0, 86.0, 77.0, 88.0, 89.0, 91.0, 94.0, 89.0, 86.0, 84.0, 83.0, 89.0]
ESCC	SBS22	C>A	0.0	0.0	0.0	0.0	1.0	1.0	0.0	2450.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
ESCC	SBS22	C>G	0.0	0.0	0.0	0.0	1.0	1.0	0.0	2450.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
ESCC	SBS22	C>T	0.0	0.0	0.0	0.0	1.0	1.0	0.0	2450.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
ESCC	SBS22	T>A	826.0	1624.0	1051.52	1401.25	4.5206647754155655e-11	2.9193161501126465e-10	100.0	2450.0	Intergenic	1.966	1.333	1.475	1	1	1				500.0	513.41	470.0	552.0	[534, 518, 498, 537, 513, 549, 487, 512, 513, 493, 526, 519, 519, 480, 484, 478, 530, 534, 500, 508, 539, 535, 540, 521, 528, 500, 511, 490, 491, 542, 526, 520, 506, 519, 531, 504, 517, 519, 531, 470, 503, 498, 510, 490, 502, 521, 487, 544, 509, 529, 518, 528, 534, 526, 526, 513, 523, 540, 509, 497, 519, 478, 496, 474, 505, 523, 504, 548, 495, 542, 505, 487, 529, 490, 494, 489, 533, 519, 491, 501, 552, 531, 527, 491, 509, 493, 509, 505, 508, 519, 526, 518, 526, 508, 531, 537, 516, 501, 494, 539]	326.0	538.11	487.0	577.0	[566, 547, 542, 526, 566, 517, 518, 537, 550, 552, 558, 543, 510, 567, 553, 533, 524, 507, 526, 540, 553, 562, 487, 514, 525, 514, 548, 538, 562, 548, 532, 569, 507, 519, 554, 523, 563, 556, 520, 525, 519, 556, 532, 530, 574, 498, 577, 529, 502, 562, 531, 536, 535, 550, 551, 542, 532, 519, 519, 526, 546, 538, 538, 547, 553, 559, 543, 507, 564, 501, 529, 541, 513, 536, 542, 548, 566, 530, 512, 556, 527, 520, 495, 541, 554, 543, 525, 551, 541, 562, 566, 541, 568, 573, 509, 554, 531, 532, 531, 557]	1624.0	1401.25	1351.0	1458.0	[1351, 1382, 1413, 1393, 1372, 1382, 1444, 1404, 1393, 1408, 1365, 1393, 1424, 1407, 1414, 1439, 1398, 1417, 1426, 1401, 1364, 1359, 1429, 1420, 1400, 1437, 1387, 1422, 1401, 1364, 1398, 1363, 1439, 1414, 1371, 1429, 1373, 1376, 1400, 1458, 1432, 1395, 1412, 1431, 1377, 1430, 1392, 1387, 1444, 1366, 1400, 1395, 1386, 1375, 1383, 1399, 1400, 1403, 1420, 1427, 1382, 1437, 1417, 1435, 1387, 1371, 1401, 1398, 1400, 1408, 1417, 1422, 1407, 1429, 1418, 1415, 1353, 1403, 1445, 1394, 1371, 1398, 1426, 1424, 1392, 1415, 1427, 1401, 1409, 1377, 1357, 1396, 1355, 1371, 1416, 1363, 1409, 1418, 1421, 1356]
ESCC	SBS22	T>C	0.0	0.0	0.0	0.0	1.0	1.0	0.0	2450.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
ESCC	SBS22	T>G	0.0	0.0	0.0	0.0	1.0	1.0	0.0	2450.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
Kidney-RCC	SBS22	C>A	535.0	1069.0	692.23	916.27	1.767355615450864e-08	1.0232011173263429e-07	1.641	97761.0	Intergenic	1.998	1.324	1.51	1	1	1	1			335.0	362.03	321.0	393.0	[353, 352, 373, 371, 378, 379, 376, 365, 357, 368, 368, 360, 358, 367, 374, 355, 380, 347, 358, 365, 369, 372, 348, 322, 343, 350, 359, 366, 372, 375, 362, 361, 366, 390, 368, 350, 357, 360, 388, 357, 343, 368, 364, 364, 393, 364, 355, 345, 338, 353, 340, 361, 351, 360, 374, 327, 369, 382, 332, 329, 376, 344, 387, 382, 357, 365, 355, 332, 373, 370, 359, 364, 393, 364, 375, 353, 367, 356, 370, 376, 356, 387, 361, 351, 321, 374, 355, 371, 350, 356, 373, 331, 390, 389, 353, 384, 357, 361, 353, 361]	200.0	330.2	288.0	361.0	[335, 355, 328, 319, 340, 332, 325, 324, 311, 337, 344, 349, 320, 318, 318, 353, 292, 332, 340, 333, 330, 313, 288, 329, 348, 330, 312, 342, 343, 328, 328, 332, 360, 337, 313, 351, 355, 323, 323, 318, 361, 353, 307, 310, 340, 348, 326, 328, 341, 350, 327, 342, 331, 345, 348, 333, 334, 316, 347, 357, 337, 303, 337, 312, 327, 342, 323, 317, 346, 317, 320, 354, 319, 328, 353, 345, 298, 319, 340, 315, 324, 336, 350, 331, 347, 329, 328, 300, 334, 317, 319, 329, 309, 297, 353, 336, 298, 345, 324, 310]	1069.0	916.27	879.0	969.0	[919, 904, 907, 917, 889, 898, 908, 918, 940, 906, 898, 899, 930, 923, 915, 900, 940, 926, 907, 909, 911, 924, 969, 958, 919, 926, 943, 907, 891, 906, 914, 915, 879, 881, 931, 906, 898, 927, 900, 929, 903, 886, 939, 933, 880, 895, 928, 936, 941, 905, 937, 910, 927, 904, 886, 949, 905, 916, 925, 922, 895, 962, 884, 915, 921, 902, 928, 956, 894, 924, 933, 893, 896, 917, 883, 910, 939, 935, 895, 918, 931, 889, 901, 924, 943, 901, 925, 931, 925, 934, 921, 945, 906, 923, 904, 888, 950, 906, 930, 936]
Kidney-RCC	SBS22	C>G	66.0	134.0	83.81	116.14	0.07896671169239804	0.23349105411716123	0.205	97761.0	Intergenic	2.03	1.386	1.465	1	1	1				35.0	43.0	30.0	59.0	[38, 31, 46, 44, 49, 43, 36, 59, 42, 47, 41, 35, 45, 53, 47, 42, 33, 41, 44, 43, 49, 32, 34, 34, 48, 45, 42, 36, 45, 42, 45, 53, 46, 37, 41, 36, 43, 47, 50, 41, 35, 42, 35, 40, 41, 30, 43, 52, 48, 42, 48, 40, 36, 50, 40, 36, 49, 36, 56, 30, 41, 48, 47, 36, 42, 57, 41, 46, 47, 50, 44, 33, 49, 45, 47, 51, 41, 41, 46, 42, 37, 46, 40, 47, 43, 43, 42, 36, 47, 51, 48, 45, 44, 46, 46, 41, 38, 42, 45, 45]	31.0	40.81	30.0	56.0	[45, 45, 41, 53, 35, 46, 42, 38, 41, 39, 40, 41, 40, 42, 41, 39, 38, 35, 41, 40, 38, 49, 43, 56, 43, 40, 42, 36, 49, 51, 48, 40, 41, 43, 40, 38, 43, 32, 35, 38, 36, 35, 38, 38, 40, 45, 37, 38, 32, 34, 46, 42, 44, 40, 42, 47, 36, 37, 38, 34, 44, 42, 48, 43, 51, 33, 39, 41, 43, 48, 41, 38, 40, 42, 46, 35, 44, 35, 35, 38, 51, 50, 39, 41, 41, 46, 37, 36, 38, 43, 42, 31, 45, 45, 30, 39, 45, 33, 40, 37]	134.0	116.14	102.0	135.0	[118, 124, 112, 105, 117, 110, 121, 104, 116, 113, 121, 123, 117, 104, 111, 120, 128, 123, 115, 117, 114, 119, 122, 109, 108, 115, 117, 127, 107, 107, 108, 106, 113, 121, 118, 125, 113, 120, 115, 120, 129, 125, 126, 123, 119, 124, 121, 111, 119, 124, 105, 118, 119, 111, 119, 117, 114, 127, 106, 135, 114, 112, 107, 122, 107, 110, 120, 114, 109, 102, 114, 128, 111, 115, 108, 114, 114, 124, 120, 120, 111, 104, 120, 111, 117, 111, 120, 128, 115, 105, 111, 123, 112, 110, 123, 119, 116, 124, 115, 119]
Kidney-RCC	SBS22	C>T	0.0	0.0	0.0	0.0	1.0	1.0	0.0	97761.0											0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]	0.0	0.0	0.0	0.0	[0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0]
Kidney-RCC	SBS22	T>A	26077.0	63785.0	38020.35	52085.96	0.0	0.0	91.92	97761.0	Intergenic	2.446	1.37	1.785	1	1	1	1	1		16957.0	18535.19	18294.0	18890.0	[18314, 18376, 18542, 18503, 18566, 18578, 18516, 18483, 18528, 18376, 18464, 18802, 18605, 18459, 18666, 18563, 18555, 18488, 18677, 18721, 18742, 18563, 18788, 18404, 18626, 18674, 18525, 18327, 18522, 18535, 18637, 18489, 18550, 18427, 18707, 18503, 18742, 18584, 18652, 18548, 18524, 18602, 18728, 18294, 18601, 18424, 18485, 18474, 18405, 18542, 18454, 18700, 18582, 18374, 18451, 18726, 18422, 18463, 18506, 18417, 18604, 18543, 18581, 18543, 18476, 18447, 18339, 18541, 18523, 18436, 18494, 18556, 18408, 18410, 18535, 18485, 18377, 18332, 18705, 18584, 18503, 18490, 18578, 18485, 18540, 18890, 18542, 18451, 18402, 18630, 18472, 18458, 18524, 18529, 18670, 18636, 18436, 18641, 18588, 18634]	9120.0	19485.16	19185.0	19710.0	[19414, 19539, 19621, 19316, 19512, 19518, 19544, 19697, 19517, 19450, 19641, 19341, 19515, 19480, 19529, 19464, 19543, 19341, 19316, 19268, 19568, 19609, 19185, 19616, 19478, 19705, 19597, 19391, 19410, 19642, 19359, 19530, 19407, 19410, 19353, 19642, 19473, 19631, 19402, 19285, 19433, 19327, 19396, 19460, 19307, 19511, 19348, 19661, 19677, 19466, 19370, 19440, 19654, 19405, 19617, 19383, 19550, 19490, 19566, 19595, 19425, 19453, 19418, 19683, 19501, 19502, 19637, 19560, 19543, 19686, 19587, 19353, 19453, 19539, 19476, 19461, 19504, 19351, 19443, 19431, 19612, 19371, 19552, 19710, 19384, 19345, 19245, 19634, 19584, 19462, 19296, 19378, 19647, 19616, 19240, 19452, 19382, 19604, 19384, 19697]	63785.0	52085.96	51744.0	52447.0	[52349, 52192, 51968, 52260, 51993, 52035, 52075, 51959, 52075, 52293, 52013, 51955, 51981, 52167, 51923, 52114, 51996, 52260, 52085, 52135, 51805, 51935, 52143, 52092, 51988, 51744, 51969, 52377, 52155, 51898, 52111, 52090, 52170, 52276, 52035, 51968, 51879, 51938, 52067, 52247, 52141, 52173, 51975, 52338, 52191, 52158, 52285, 51996, 52011, 52099, 52268, 51951, 51892, 52350, 52051, 51973, 52149, 52182, 52034, 52068, 52106, 52128, 52119, 51874, 52115, 52148, 52121, 52009, 52066, 51993, 52031, 52217, 52257, 52198, 52071, 52164, 52211, 52447, 51960, 52082, 51970, 52213, 51973, 51915, 52166, 51875, 52327, 52020, 52073, 52020, 52362, 52279, 51909, 51968, 52171, 52000, 52263, 51866, 52124, 51785]
Kidney-RCC	SBS22	T>C	1092.0	2369.0	1411.65	2053.53	2.0697438724760357e-15	1.5531325035094076e-14	3.54	97761.0	Intergenic	2.169	1.455	1.491	1	1	1				684.0	727.09	662.0	808.0	[714, 738, 688, 743, 751, 729, 754, 726, 733, 729, 735, 719, 720, 726, 753, 699, 680, 739, 715, 743, 720, 746, 721, 787, 727, 676, 727, 748, 714, 744, 731, 729, 742, 714, 713, 767, 738, 712, 707, 717, 761, 703, 757, 690, 762, 727, 691, 708, 734, 753, 723, 748, 682, 726, 725, 731, 748, 692, 703, 740, 731, 715, 673, 700, 696, 706, 728, 702, 737, 808, 768, 775, 687, 733, 738, 741, 731, 729, 737, 744, 720, 740, 748, 686, 705, 726, 716, 729, 722, 737, 730, 738, 695, 734, 738, 775, 662, 739, 733, 739]	408.0	684.56	631.0	740.0	[714, 689, 692, 661, 650, 669, 691, 676, 658, 645, 647, 693, 640, 692, 670, 709, 702, 720, 681, 648, 712, 710, 684, 681, 723, 706, 655, 654, 639, 705, 671, 683, 682, 685, 673, 649, 660, 707, 692, 690, 634, 659, 696, 657, 672, 735, 669, 715, 655, 677, 728, 705, 727, 695, 693, 669, 692, 695, 703, 689, 662, 701, 686, 707, 684, 711, 681, 711, 688, 669, 687, 665, 685, 676, 710, 638, 652, 711, 704, 691, 682, 682, 706, 676, 693, 672, 709, 736, 740, 656, 724, 664, 678, 693, 688, 650, 721, 690, 673, 631]	2369.0	2053.53	1997.0	2113.0	[2031, 2041, 2083, 2063, 2061, 2064, 2022, 2060, 2075, 2089, 2086, 2055, 2110, 2048, 2043, 2054, 2084, 2007, 2067, 2073, 2031, 2010, 2064, 2001, 2018, 2079, 2084, 2064, 2113, 2019, 2060, 2053, 2045, 2069, 2080, 2049, 2065, 2045, 2068, 2055, 2072, 2106, 2015, 2112, 2034, 2010, 2107, 2040, 2076, 2031, 2016, 2008, 2059, 2041, 2043, 2063, 2021, 2078, 2058, 2034, 2074, 2047, 2105, 2058, 2089, 2045, 2052, 2052, 2038, 1997, 2011, 2024, 2095, 2055, 2016, 2085, 2081, 2032, 2027, 2036, 2065, 2046, 2013, 2100, 2067, 2070, 2032, 2000, 2007, 2070, 2007, 2058, 2092, 2038, 2033, 2042, 2083, 2043, 2060, 2096]
Kidney-RCC	SBS22	T>G	827.0	1807.0	1123.64	1515.0	4.5261279286320206e-17	3.5397765897211396e-16	2.694	97761.0	Intergenic	2.185	1.348	1.621	1	1	1	1			493.0	549.01	487.0	598.0	[544, 536, 568, 571, 553, 523, 586, 551, 552, 556, 531, 575, 539, 549, 560, 549, 586, 511, 569, 551, 566, 590, 547, 573, 547, 575, 537, 577, 548, 512, 522, 571, 547, 569, 588, 528, 531, 565, 501, 564, 559, 563, 566, 570, 546, 586, 507, 549, 521, 567, 510, 494, 542, 555, 555, 543, 555, 487, 558, 556, 534, 502, 538, 585, 562, 539, 564, 539, 560, 598, 540, 562, 517, 545, 594, 547, 559, 507, 533, 508, 522, 531, 573, 574, 547, 512, 543, 574, 515, 552, 543, 542, 558, 559, 564, 509, 566, 578, 554, 545]	334.0	574.63	528.0	642.0	[598, 578, 595, 570, 590, 636, 550, 590, 600, 534, 589, 584, 571, 583, 535, 582, 555, 595, 583, 588, 550, 573, 578, 581, 541, 588, 576, 540, 572, 597, 583, 581, 589, 577, 576, 543, 528, 601, 565, 542, 592, 567, 579, 532, 594, 554, 594, 554, 610, 543, 531, 584, 578, 593, 577, 599, 557, 586, 565, 566, 579, 597, 583, 545, 590, 600, 557, 607, 552, 538, 608, 597, 582, 592, 553, 609, 571, 566, 575, 601, 545, 604, 587, 584, 642, 569, 551, 579, 573, 578, 551, 582, 554, 553, 555, 588, 559, 565, 541, 559]	1807.0	1515.0	1446.0	1594.0	[1496, 1530, 1475, 1505, 1491, 1484, 1499, 1497, 1493, 1549, 1519, 1477, 1531, 1503, 1539, 1512, 1500, 1534, 1486, 1499, 1523, 1478, 1513, 1480, 1549, 1477, 1529, 1523, 1518, 1526, 1538, 1493, 1498, 1494, 1474, 1566, 1577, 1469, 1574, 1530, 1484, 1511, 1496, 1534, 1506, 1499, 1540, 1537, 1507, 1528, 1594, 1556, 1517, 1492, 1505, 1499, 1532, 1568, 1517, 1514, 1526, 1543, 1514, 1511, 1490, 1494, 1516, 1489, 1534, 1505, 1494, 1481, 1541, 1499, 1489, 1485, 1509, 1560, 1526, 1526, 1569, 1498, 1481, 1481, 1446, 1559, 1539, 1490, 1553, 1516, 1543, 1513, 1526, 1525, 1520, 1546, 1510, 1489, 1544, 1536]
Liver-HCC	SBS22	C>A	329.0	539.0	389.7	480.0	0.004036294171927267	0.015548961268503992	0.69	125866.0	Intergenic	1.638	1.232	1.33	1	1	1				181.0	200.68	178.0	238.0	[195, 191, 193, 187, 187, 204, 200, 224, 199, 188, 212, 190, 217, 209, 218, 219, 222, 211, 218, 191, 211, 193, 185, 191, 191, 208, 193, 207, 191, 200, 188, 198, 209, 204, 238, 207, 201, 196, 223, 190, 187, 193, 182, 217, 204, 187, 195, 204, 203, 210, 212, 215, 209, 202, 208, 189, 190, 192, 189, 207, 203, 181, 202, 187, 198, 197, 203, 201, 187, 207, 186, 198, 225, 209, 178, 220, 195, 210, 196, 202, 208, 201, 198, 208, 225, 196, 199, 191, 185, 211, 186, 188, 212, 198, 205, 200, 188, 199, 194, 197]	148.0	189.02	156.0	226.0	[168, 211, 201, 209, 176, 191, 196, 176, 200, 183, 171, 194, 191, 197, 178, 209, 168, 188, 194, 186, 178, 194, 180, 182, 197, 188, 173, 193, 174, 209, 180, 183, 191, 182, 188, 175, 182, 226, 181, 201, 205, 188, 186, 180, 200, 166, 209, 193, 193, 175, 185, 187, 156, 190, 201, 197, 194, 198, 179, 172, 187, 198, 182, 223, 193, 180, 183, 181, 176, 190, 178, 178, 183, 178, 202, 181, 211, 184, 191, 204, 193, 191, 176, 189, 180, 197, 190, 186, 206, 183, 195, 196, 192, 211, 184, 187, 188, 181, 193, 203]	539.0	480.0	441.0	514.0	[504, 467, 475, 473, 505, 470, 480, 471, 469, 497, 487, 486, 464, 460, 477, 444, 482, 472, 459, 494, 482, 484, 508, 495, 479, 478, 506, 468, 503, 465, 500, 487, 469, 481, 441, 489, 486, 444, 464, 481, 480, 489, 505, 473, 468, 514, 467, 472, 478, 487, 473, 469, 505, 480, 459, 482, 489, 480, 503, 492, 483, 491, 483, 460, 478, 488, 481, 492, 505, 474, 505, 491, 461, 483, 487, 469, 463, 473, 481, 464, 469, 476, 493, 470, 465, 478, 480, 492, 480, 474, 489, 486, 464, 462, 481, 480, 492, 494, 481, 471]
Liver-HCC	SBS22	C>G	100.0	131.0	99.53	129.57	1.0	1.0	0.184	125866.0	Intergenic	1.31	1.302	1.006							48.0	51.47	36.0	66.0	[51, 51, 49, 48, 56, 53, 52, 56, 48, 52, 53, 39, 44, 48, 47, 63, 54, 49, 58, 36, 49, 51, 55, 50, 41, 50, 52, 50, 64, 57, 56, 52, 56, 50, 44, 54, 49, 45, 49, 54, 56, 54, 58, 51, 52, 44, 51, 48, 48, 54, 51, 43, 56, 54, 64, 58, 59, 50, 62, 54, 56, 50, 45, 49, 58, 66, 57, 45, 47, 46, 48, 46, 48, 56, 61, 39, 60, 50, 58, 51, 57, 48, 54, 52, 47, 49, 58, 46, 62, 44, 55, 46, 46, 39, 49, 57, 49, 50, 60, 41]	52.0	48.06	32.0	65.0	[38, 54, 46, 46, 44, 46, 45, 43, 59, 53, 47, 65, 48, 50, 35, 42, 41, 54, 45, 59, 55, 43, 46, 54, 63, 42, 46, 44, 52, 41, 54, 49, 49, 50, 44, 43, 53, 38, 52, 46, 45, 50, 32, 59, 41, 55, 42, 46, 44, 44, 47, 59, 47, 54, 38, 46, 55, 56, 46, 43, 46, 49, 43, 44, 47, 41, 41, 52, 58, 65, 53, 47, 41, 39, 49, 51, 45, 47, 49, 43, 44, 58, 49, 57, 59, 48, 43, 45, 38, 51, 43, 48, 53, 57, 51, 54, 43, 55, 43, 44]	131.0	129.57	112.0	147.0	[139, 123, 134, 135, 129, 133, 133, 131, 124, 124, 129, 127, 138, 130, 147, 123, 134, 126, 125, 133, 127, 134, 127, 124, 124, 137, 130, 134, 112, 130, 119, 127, 125, 131, 142, 131, 127, 145, 129, 129, 129, 124, 139, 120, 135, 129, 137, 134, 136, 134, 132, 126, 128, 123, 126, 124, 114, 123, 122, 132, 127, 130, 140, 135, 127, 122, 130, 132, 125, 119, 128, 135, 139, 133, 119, 140, 126, 131, 123, 134, 127, 124, 126, 121, 125, 133, 130, 139, 129, 134, 130, 134, 129, 132, 130, 118, 138, 125, 126, 144]
Liver-HCC	SBS22	C>T	131.0	193.0	146.12	179.5	0.26679980025328964	0.6129507100350531	0.257	125866.0	Intergenic	1.473	1.228	1.199	1	1					55.0	73.96	60.0	91.0	[91, 65, 82, 72, 76, 76, 70, 81, 76, 77, 62, 79, 71, 75, 73, 75, 76, 72, 72, 79, 67, 74, 77, 61, 66, 75, 73, 82, 69, 83, 83, 77, 85, 62, 79, 69, 71, 84, 73, 67, 74, 67, 81, 71, 68, 82, 73, 83, 78, 69, 65, 78, 73, 70, 71, 79, 86, 74, 63, 62, 81, 77, 79, 69, 78, 74, 79, 70, 72, 82, 88, 72, 67, 71, 65, 75, 72, 60, 71, 71, 74, 77, 76, 71, 90, 74, 68, 67, 77, 77, 60, 77, 62, 82, 78, 76, 77, 67, 68, 81]	76.0	72.16	51.0	93.0	[76, 71, 59, 75, 74, 75, 75, 63, 73, 87, 77, 69, 66, 52, 71, 66, 83, 71, 81, 70, 79, 68, 68, 72, 81, 79, 79, 68, 61, 58, 72, 72, 85, 79, 67, 85, 65, 72, 86, 79, 81, 80, 74, 65, 87, 74, 75, 55, 73, 84, 73, 59, 75, 72, 66, 79, 51, 83, 73, 75, 67, 69, 66, 61, 70, 73, 65, 83, 80, 66, 73, 69, 76, 68, 84, 74, 77, 69, 67, 59, 78, 77, 76, 80, 56, 69, 93, 78, 74, 59, 71, 56, 70, 74, 69, 69, 73, 67, 80, 68]	193.0	179.5	155.0	199.0	[161, 190, 184, 177, 178, 176, 183, 181, 177, 160, 187, 176, 188, 199, 182, 185, 167, 183, 173, 177, 182, 183, 181, 194, 179, 173, 173, 175, 195, 184, 169, 176, 155, 183, 181, 174, 189, 172, 168, 178, 173, 177, 170, 188, 169, 170, 177, 186, 175, 173, 186, 187, 178, 185, 188, 170, 190, 170, 188, 187, 177, 178, 179, 197, 178, 179, 181, 171, 173, 177, 165, 183, 182, 188, 176, 175, 178, 196, 188, 194, 178, 171, 173, 174, 180, 183, 165, 180, 176, 188, 193, 192, 193, 171, 179, 182, 177, 191, 177, 177]
Liver-HCC	SBS22	T>A	44378.0	74424.0	51021.55	67984.41	5.506187439126582e-166	1.349792283070922e-164	94.388	125866.0	Intergenic	1.677	1.332	1.259	1	1					27479.0	24843.84	24547.0	25197.0	[24734, 24792, 24960, 24849, 25074, 24862, 24646, 24884, 25180, 25055, 25117, 24871, 24813, 24717, 24845, 24743, 24742, 24824, 24852, 24839, 24872, 24676, 24621, 24738, 24944, 24884, 24950, 24674, 24762, 24829, 24861, 24685, 24754, 25057, 24847, 24713, 24997, 24604, 24752, 24896, 24713, 24809, 25148, 24882, 24892, 24753, 24671, 24959, 25110, 24979, 24952, 24722, 24966, 25197, 25003, 24790, 24982, 24780, 24589, 24934, 24547, 24909, 24685, 25030, 24688, 24811, 24852, 24890, 24840, 24834, 24893, 24976, 24833, 24615, 24826, 24707, 24613, 24779, 25110, 24806, 24768, 24951, 24823, 24774, 24968, 24945, 24749, 24804, 24802, 25075, 24899, 24671, 24738, 25178, 24726, 24748, 24785, 24869, 24803, 24718]	16899.0	26177.71	25740.0	26567.0	[26408, 25974, 26133, 26025, 26059, 26246, 26195, 26289, 26041, 26445, 26152, 26319, 26284, 26078, 26251, 26032, 26379, 26171, 26095, 26313, 26045, 26296, 26225, 26039, 25999, 26209, 26264, 25927, 26234, 26086, 26264, 26249, 26063, 26183, 26023, 26093, 26262, 26222, 26353, 26115, 26095, 26290, 26122, 26037, 26333, 26420, 26251, 26245, 25961, 26222, 26169, 26513, 25740, 26156, 25956, 26146, 26206, 26397, 26054, 25964, 26203, 26290, 26208, 26013, 26292, 26059, 26567, 25851, 26103, 26005, 26424, 26035, 26208, 26376, 26151, 26344, 26090, 26353, 26164, 26147, 26281, 26231, 26340, 25973, 26010, 25955, 26331, 25959, 26150, 26009, 26129, 26380, 26205, 26206, 26260, 26160, 26219, 26136, 26286, 26351]	74424.0	67984.41	67544.0	68408.0	[67842, 68251, 67921, 68120, 67871, 67876, 68168, 67866, 67818, 67544, 67778, 67818, 67921, 68210, 67946, 68238, 67890, 67983, 68087, 67858, 68069, 68034, 68154, 68195, 68076, 67914, 67784, 68408, 68013, 68091, 67908, 68070, 68148, 67779, 68143, 68189, 67764, 68157, 67899, 67988, 68175, 67936, 67753, 68103, 67748, 67849, 68088, 67792, 67904, 67790, 67901, 67746, 68268, 67679, 68011, 68053, 67841, 67888, 68355, 68118, 68231, 67848, 68131, 67979, 67993, 68140, 67656, 68265, 68093, 68130, 67696, 67978, 67961, 68021, 68007, 67918, 68311, 67879, 67726, 68065, 67942, 67817, 67855, 68279, 68027, 68100, 67935, 68233, 68073, 67914, 67978, 67914, 68019, 67628, 68002, 68040, 68022, 67994, 67951, 67903]
Liver-HCC	SBS22	T>C	1389.0	2068.0	1447.04	2013.94	0.17099394413495111	0.4386838961791334	2.747	125866.0	Intergenic	1.489	1.392	1.07							922.0	732.25	667.0	797.0	[738, 737, 728, 686, 724, 715, 753, 734, 751, 743, 715, 733, 700, 722, 714, 738, 722, 766, 708, 714, 742, 765, 718, 676, 703, 743, 734, 690, 721, 740, 754, 778, 756, 749, 723, 745, 765, 726, 730, 728, 754, 712, 757, 721, 774, 695, 714, 721, 744, 717, 741, 759, 716, 732, 755, 721, 728, 726, 667, 774, 747, 753, 718, 727, 736, 797, 737, 716, 759, 737, 745, 694, 734, 722, 680, 736, 724, 725, 694, 731, 724, 718, 747, 748, 746, 779, 739, 695, 765, 742, 760, 753, 728, 724, 735, 717, 729, 717, 755, 737]	467.0	714.79	666.0	768.0	[696, 744, 731, 694, 730, 754, 707, 704, 709, 706, 733, 715, 719, 723, 719, 721, 685, 697, 758, 720, 695, 706, 705, 754, 734, 768, 713, 705, 701, 691, 725, 688, 691, 679, 753, 705, 693, 694, 709, 687, 689, 710, 764, 723, 710, 711, 710, 690, 720, 718, 689, 724, 733, 733, 695, 687, 690, 752, 724, 688, 763, 721, 718, 712, 701, 712, 700, 721, 736, 720, 707, 758, 725, 724, 705, 688, 757, 710, 717, 688, 716, 738, 689, 759, 698, 722, 694, 666, 725, 721, 740, 694, 721, 719, 727, 686, 694, 712, 729, 725]	2068.0	2013.94	1947.0	2100.0	[2022, 1979, 2005, 2072, 2009, 1990, 2005, 2018, 2008, 2018, 2016, 2009, 2042, 2020, 2029, 2001, 2055, 1999, 1989, 2029, 2023, 1988, 2038, 2028, 2022, 1958, 2015, 2065, 2040, 2026, 1984, 1992, 2022, 2035, 1991, 2008, 2003, 2042, 2020, 2047, 2013, 2039, 1947, 2018, 1971, 2054, 2035, 2050, 2002, 2018, 2026, 1976, 2014, 1997, 2011, 2052, 2043, 1979, 2066, 1993, 1949, 1985, 2030, 2029, 2020, 1953, 2018, 2023, 1962, 2002, 2014, 2008, 2011, 2017, 2077, 2039, 1977, 2022, 2049, 2043, 2022, 2000, 2022, 1960, 2017, 1963, 2032, 2100, 1974, 1999, 1970, 2012, 2015, 2020, 1998, 2052, 2038, 2032, 1975, 1999]
Liver-HCC	SBS22	T>G	857.0	1327.0	941.55	1246.57	0.011710751870216836	0.04192055967225862	1.735	125866.0	Intergenic	1.548	1.324	1.17	1						532.0	458.81	408.0	506.0	[428, 469, 479, 455, 502, 471, 447, 436, 433, 467, 467, 458, 462, 470, 474, 472, 452, 440, 427, 436, 470, 457, 450, 471, 421, 457, 486, 488, 442, 439, 483, 449, 453, 441, 458, 438, 438, 432, 440, 466, 433, 474, 448, 446, 408, 475, 466, 473, 475, 472, 468, 431, 467, 454, 480, 478, 425, 473, 459, 476, 500, 481, 445, 501, 461, 451, 479, 458, 454, 439, 458, 478, 470, 437, 453, 447, 443, 460, 431, 477, 462, 440, 476, 456, 464, 477, 444, 458, 479, 476, 452, 443, 477, 421, 506, 454, 484, 436, 491, 457]	325.0	482.74	430.0	537.0	[537, 486, 474, 493, 434, 497, 496, 498, 516, 474, 456, 512, 488, 464, 488, 459, 491, 469, 439, 500, 479, 479, 465, 508, 500, 497, 463, 484, 483, 464, 484, 517, 483, 482, 491, 486, 516, 527, 497, 499, 484, 471, 494, 493, 513, 488, 474, 491, 481, 473, 499, 461, 443, 490, 463, 450, 483, 463, 473, 494, 489, 484, 488, 470, 452, 490, 461, 485, 490, 511, 486, 502, 467, 486, 486, 472, 520, 489, 485, 481, 473, 497, 480, 477, 445, 472, 495, 483, 506, 430, 516, 459, 463, 486, 457, 465, 503, 486, 461, 470]	1327.0	1246.57	1198.0	1323.0	[1224, 1232, 1238, 1241, 1252, 1222, 1241, 1261, 1243, 1244, 1266, 1213, 1236, 1247, 1226, 1256, 1243, 1280, 1323, 1252, 1238, 1249, 1272, 1212, 1266, 1235, 1240, 1217, 1263, 1285, 1222, 1221, 1249, 1262, 1245, 1263, 1239, 1233, 1248, 1228, 1270, 1250, 1247, 1250, 1270, 1226, 1245, 1228, 1237, 1245, 1219, 1297, 1275, 1250, 1256, 1263, 1279, 1253, 1253, 1220, 1198, 1222, 1256, 1224, 1269, 1243, 1250, 1245, 1239, 1246, 1247, 1209, 1246, 1265, 1245, 1267, 1227, 1233, 1272, 1231, 1250, 1249, 1229, 1253, 1272, 1239, 1253, 1247, 1203, 1280, 1224, 1280, 1249, 1277, 1225, 1271, 1201, 1262, 1240, 1259]

Summary across all cancer types
signature	mutation_type	strand	fold_change_1.1	len(fold_change_1.1_cancer_types)	fold_change_1.2	len(fold_change_1.2_cancer_types)	fold_change_1.3	len(fold_change_1.3_cancer_types)	fold_change_1.5	len(fold_change_1.5_cancer_types)	fold_change_1.75	len(fold_change_1.75_cancer_types)	fold_change_2+	len(fold_change_2+_cancer_types)	all_cancer_types_list	len(all_cancer_types_list)	avg_fold_change
SBS22	T>A	Intergenic	['Biliary-AdenoCA', 'ESCC', 'Kidney-RCC', 'Liver-HCC']	4	['Biliary-AdenoCA', 'ESCC', 'Kidney-RCC', 'Liver-HCC']	4	['Biliary-AdenoCA', 'ESCC', 'Kidney-RCC']	3	['Kidney-RCC']	1	['Kidney-RCC']	1	[]	0	['Biliary-AdenoCA', 'ESCC', 'Kidney-RCC', 'Liver-HCC']	4	1.3875