# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. # For real mutations on transcribed:T, untranscribed:U, bitranscribed:B and nontranscribed:N strands averaged across cancer types. MutationType Across_All_Cancer_Types T:A[C>A]A 21.0 U:A[C>A]A 14.75 B:A[C>A]A 0.0 N:A[C>A]A 113.625 T:A[C>A]C 5.125 U:A[C>A]C 3.125 B:A[C>A]C 0.0 N:A[C>A]C 36.375 T:A[C>A]G 0.0 U:A[C>A]G 0.0 B:A[C>A]G 0.0 N:A[C>A]G 0.0 T:A[C>A]T 0.0 U:A[C>A]T 0.0 B:A[C>A]T 0.0 N:A[C>A]T 0.125 T:A[C>G]A 1.5 U:A[C>G]A 1.0 B:A[C>G]A 0.0 N:A[C>G]A 22.375 T:A[C>G]C 0.5 U:A[C>G]C 0.375 B:A[C>G]C 0.0 N:A[C>G]C 8.0 T:A[C>G]G 0.125 U:A[C>G]G 0.0 B:A[C>G]G 0.0 N:A[C>G]G 0.625 T:A[C>G]T 0.0 U:A[C>G]T 0.0 B:A[C>G]T 0.0 N:A[C>G]T 0.0 T:A[C>T]A 3.375 U:A[C>T]A 1.75 B:A[C>T]A 0.0 N:A[C>T]A 31.125 T:A[C>T]C 8.25 U:A[C>T]C 6.25 B:A[C>T]C 0.0 N:A[C>T]C 41.875 T:A[C>T]G 0.0 U:A[C>T]G 0.0 B:A[C>T]G 0.0 N:A[C>T]G 0.0 T:A[C>T]T 1.0 U:A[C>T]T 0.5 B:A[C>T]T 0.0 N:A[C>T]T 16.25 T:A[T>A]A 6.125 U:A[T>A]A 4.625 B:A[T>A]A 0.0 N:A[T>A]A 53.125 T:A[T>A]C 6.25 U:A[T>A]C 4.0 B:A[T>A]C 0.0 N:A[T>A]C 48.0 T:A[T>A]G 0.0 U:A[T>A]G 0.0 B:A[T>A]G 0.0 N:A[T>A]G 1.375 T:A[T>A]T 31.875 U:A[T>A]T 32.375 B:A[T>A]T 0.0 N:A[T>A]T 183.75 T:A[T>C]A 0.0 U:A[T>C]A 0.0 B:A[T>C]A 0.0 N:A[T>C]A 0.0 T:A[T>C]C 111.5 U:A[T>C]C 93.375 B:A[T>C]C 0.125 N:A[T>C]C 477.375 T:A[T>C]G 0.0 U:A[T>C]G 0.0 B:A[T>C]G 0.0 N:A[T>C]G 1.75 T:A[T>C]T 54.75 U:A[T>C]T 46.5 B:A[T>C]T 0.0 N:A[T>C]T 251.25 T:A[T>G]A 5.25 U:A[T>G]A 4.5 B:A[T>G]A 0.0 N:A[T>G]A 45.5 T:A[T>G]C 2.125 U:A[T>G]C 1.875 B:A[T>G]C 0.0 N:A[T>G]C 26.375 T:A[T>G]G 0.75 U:A[T>G]G 0.875 B:A[T>G]G 0.0 N:A[T>G]G 16.5 T:A[T>G]T 126.375 U:A[T>G]T 134.25 B:A[T>G]T 0.125 N:A[T>G]T 778.625 T:C[C>A]A 0.875 U:C[C>A]A 0.375 B:C[C>A]A 0.0 N:C[C>A]A 11.25 T:C[C>A]C 6.375 U:C[C>A]C 5.125 B:C[C>A]C 0.0 N:C[C>A]C 44.75 T:C[C>A]G 0.0 U:C[C>A]G 0.0 B:C[C>A]G 0.0 N:C[C>A]G 0.0 T:C[C>A]T 0.125 U:C[C>A]T 0.0 B:C[C>A]T 0.0 N:C[C>A]T 4.125 T:C[C>G]A 0.5 U:C[C>G]A 0.0 B:C[C>G]A 0.0 N:C[C>G]A 7.25 T:C[C>G]C 0.0 U:C[C>G]C 0.0 B:C[C>G]C 0.0 N:C[C>G]C 0.0 T:C[C>G]G 0.0 U:C[C>G]G 0.0 B:C[C>G]G 0.0 N:C[C>G]G 0.125 T:C[C>G]T 0.0 U:C[C>G]T 0.0 B:C[C>G]T 0.0 N:C[C>G]T 0.0 T:C[C>T]A 2.375 U:C[C>T]A 2.0 B:C[C>T]A 0.0 N:C[C>T]A 24.25 T:C[C>T]C 10.875 U:C[C>T]C 10.75 B:C[C>T]C 0.0 N:C[C>T]C 49.625 T:C[C>T]G 14.625 U:C[C>T]G 15.75 B:C[C>T]G 0.0 N:C[C>T]G 59.5 T:C[C>T]T 9.875 U:C[C>T]T 10.875 B:C[C>T]T 0.0 N:C[C>T]T 53.75 T:C[T>A]A 4.5 U:C[T>A]A 3.5 B:C[T>A]A 0.0 N:C[T>A]A 39.375 T:C[T>A]C 448.875 U:C[T>A]C 402.25 B:C[T>A]C 1.875 N:C[T>A]C 2101.125 T:C[T>A]G 158.375 U:C[T>A]G 154.875 B:C[T>A]G 0.375 N:C[T>A]G 739.25 T:C[T>A]T 1090.125 U:C[T>A]T 1237.5 B:C[T>A]T 6.25 N:C[T>A]T 6100.0 T:C[T>C]A 142.25 U:C[T>C]A 127.125 B:C[T>C]A 0.125 N:C[T>C]A 673.625 T:C[T>C]C 1545.0 U:C[T>C]C 1476.75 B:C[T>C]C 10.25 N:C[T>C]C 7720.25 T:C[T>C]G 805.0 U:C[T>C]G 799.5 B:C[T>C]G 5.25 N:C[T>C]G 3955.25 T:C[T>C]T 4441.375 U:C[T>C]T 4743.625 B:C[T>C]T 32.25 N:C[T>C]T 24858.5 T:C[T>G]A 0.25 U:C[T>G]A 0.25 B:C[T>G]A 0.0 N:C[T>G]A 12.375 T:C[T>G]C 4.25 U:C[T>G]C 3.25 B:C[T>G]C 0.0 N:C[T>G]C 38.5 T:C[T>G]G 0.0 U:C[T>G]G 0.0 B:C[T>G]G 0.0 N:C[T>G]G 0.0 T:C[T>G]T 43.25 U:C[T>G]T 45.125 B:C[T>G]T 0.0 N:C[T>G]T 281.625 T:G[C>A]A 22.625 U:G[C>A]A 19.75 B:G[C>A]A 0.0 N:G[C>A]A 126.5 T:G[C>A]C 7.5 U:G[C>A]C 5.625 B:G[C>A]C 0.0 N:G[C>A]C 47.625 T:G[C>A]G 0.0 U:G[C>A]G 0.0 B:G[C>A]G 0.0 N:G[C>A]G 0.125 T:G[C>A]T 0.0 U:G[C>A]T 0.0 B:G[C>A]T 0.0 N:G[C>A]T 0.25 T:G[C>G]A 1.0 U:G[C>G]A 0.75 B:G[C>G]A 0.0 N:G[C>G]A 15.5 T:G[C>G]C 1.75 U:G[C>G]C 1.625 B:G[C>G]C 0.0 N:G[C>G]C 16.625 T:G[C>G]G 0.0 U:G[C>G]G 0.0 B:G[C>G]G 0.0 N:G[C>G]G 0.0 T:G[C>G]T 0.75 U:G[C>G]T 1.375 B:G[C>G]T 0.0 N:G[C>G]T 14.25 T:G[C>T]A 7.625 U:G[C>T]A 6.875 B:G[C>T]A 0.0 N:G[C>T]A 49.5 T:G[C>T]C 0.0 U:G[C>T]C 0.0 B:G[C>T]C 0.0 N:G[C>T]C 0.0 T:G[C>T]G 16.375 U:G[C>T]G 16.25 B:G[C>T]G 0.0 N:G[C>T]G 66.5 T:G[C>T]T 0.0 U:G[C>T]T 0.0 B:G[C>T]T 0.0 N:G[C>T]T 0.0 T:G[T>A]A 0.0 U:G[T>A]A 0.0 B:G[T>A]A 0.0 N:G[T>A]A 0.0 T:G[T>A]C 44.375 U:G[T>A]C 43.25 B:G[T>A]C 0.0 N:G[T>A]C 240.375 T:G[T>A]G 1.5 U:G[T>A]G 2.875 B:G[T>A]G 0.0 N:G[T>A]G 26.375 T:G[T>A]T 84.625 U:G[T>A]T 99.25 B:G[T>A]T 0.0 N:G[T>A]T 523.375 T:G[T>C]A 0.0 U:G[T>C]A 0.0 B:G[T>C]A 0.0 N:G[T>C]A 0.875 T:G[T>C]C 205.375 U:G[T>C]C 216.875 B:G[T>C]C 0.5 N:G[T>C]C 1007.25 T:G[T>C]G 35.625 U:G[T>C]G 39.125 B:G[T>C]G 0.0 N:G[T>C]G 201.0 T:G[T>C]T 86.625 U:G[T>C]T 99.125 B:G[T>C]T 0.0 N:G[T>C]T 502.875 T:G[T>G]A 1.125 U:G[T>G]A 1.0 B:G[T>G]A 0.0 N:G[T>G]A 14.875 T:G[T>G]C 0.125 U:G[T>G]C 0.125 B:G[T>G]C 0.0 N:G[T>G]C 4.75 T:G[T>G]G 3.0 U:G[T>G]G 3.5 B:G[T>G]G 0.0 N:G[T>G]G 33.125 T:G[T>G]T 66.25 U:G[T>G]T 78.125 B:G[T>G]T 0.0 N:G[T>G]T 440.25 T:T[C>A]A 0.375 U:T[C>A]A 0.25 B:T[C>A]A 0.0 N:T[C>A]A 9.25 T:T[C>A]C 0.0 U:T[C>A]C 0.0 B:T[C>A]C 0.0 N:T[C>A]C 0.0 T:T[C>A]G 0.0 U:T[C>A]G 0.0 B:T[C>A]G 0.0 N:T[C>A]G 0.0 T:T[C>A]T 0.5 U:T[C>A]T 0.5 B:T[C>A]T 0.0 N:T[C>A]T 17.375 T:T[C>G]A 59.375 U:T[C>G]A 55.125 B:T[C>G]A 0.125 N:T[C>G]A 223.125 T:T[C>G]C 2.25 U:T[C>G]C 2.125 B:T[C>G]C 0.0 N:T[C>G]C 16.0 T:T[C>G]G 0.5 U:T[C>G]G 0.75 B:T[C>G]G 0.0 N:T[C>G]G 4.5 T:T[C>G]T 1.25 U:T[C>G]T 1.375 B:T[C>G]T 0.0 N:T[C>G]T 10.75 T:T[C>T]A 4.75 U:T[C>T]A 4.375 B:T[C>T]A 0.0 N:T[C>T]A 27.625 T:T[C>T]C 0.0 U:T[C>T]C 0.0 B:T[C>T]C 0.0 N:T[C>T]C 0.375 T:T[C>T]G 0.0 U:T[C>T]G 0.0 B:T[C>T]G 0.0 N:T[C>T]G 1.125 T:T[C>T]T 1.0 U:T[C>T]T 1.0 B:T[C>T]T 0.0 N:T[C>T]T 14.75 T:T[T>A]A 0.0 U:T[T>A]A 0.125 B:T[T>A]A 0.0 N:T[T>A]A 3.5 T:T[T>A]C 64.875 U:T[T>A]C 63.625 B:T[T>A]C 0.125 N:T[T>A]C 343.0 T:T[T>A]G 10.25 U:T[T>A]G 13.75 B:T[T>A]G 0.0 N:T[T>A]G 82.5 T:T[T>A]T 31.375 U:T[T>A]T 43.75 B:T[T>A]T 0.0 N:T[T>A]T 220.75 T:T[T>C]A 17.875 U:T[T>C]A 22.25 B:T[T>C]A 0.0 N:T[T>C]A 123.625 T:T[T>C]C 230.875 U:T[T>C]C 254.625 B:T[T>C]C 0.875 N:T[T>C]C 1173.125 T:T[T>C]G 18.25 U:T[T>C]G 25.0 B:T[T>C]G 0.0 N:T[T>C]G 140.25 T:T[T>C]T 304.0 U:T[T>C]T 373.875 B:T[T>C]T 1.25 N:T[T>C]T 1711.25 T:T[T>G]A 0.0 U:T[T>G]A 0.0 B:T[T>G]A 0.0 N:T[T>G]A 0.0 T:T[T>G]C 0.0 U:T[T>G]C 0.0 B:T[T>G]C 0.0 N:T[T>G]C 1.0 T:T[T>G]G 1.75 U:T[T>G]G 2.875 B:T[T>G]G 0.0 N:T[T>G]G 33.125 T:T[T>G]T 39.375 U:T[T>G]T 50.75 B:T[T>G]T 0.0 N:T[T>G]T 298.75 # There must be at least 1000 mutations on the strands. # Signature and mutation type must have at least 5% of all signature mutations on the strands. # Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1. cancer_type signature mutation_type Transcribed_real_count UnTranscribed_real_count NonTranscribed_real_count Transcribed_mean_sims_count UnTranscribed_mean_sims_count NonTranscribed_mean_sims_count transcribed_versus_untranscribed_p_value transcribed_versus_untranscribed_q_value percentage_of_mutations_on_strands signature_number_of_mutations_on_strands significant_strand FC_REAL FC_SIMS FC fold_change_1.1 fold_change_1.2 fold_change_1.3 fold_change_1.5 fold_change_1.75 fold_change_2+ Transcribed_real_count.1 Transcribed_mean_sims_count.1 Transcribed_min_sims_count Transcribed_max_sims_count Transcribed_sims_count_list UnTranscribed_real_count.1 UnTranscribed_mean_sims_count.1 UnTranscribed_min_sims_count UnTranscribed_max_sims_count UnTranscribed_sims_count_list NonTranscribed_real_count.1 NonTranscribed_mean_sims_count.1 NonTranscribed_min_sims_count NonTranscribed_max_sims_count NonTranscribed_sims_count_list ESCC SBS17a C>A 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7035.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS17a C>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7035.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS17a C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7035.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS17a T>A 58.0 49.0 224.0 65.99 73.45 192.88 0.3035382106185859 0.6740588167028176 4.705 7035.0 Transcribed 1.184 0.898 1.317 1 1 1 58.0 65.99 49.0 80.0 [57, 51, 70, 66, 80, 68, 57, 59, 52, 78, 67, 63, 63, 70, 73, 57, 70, 69, 72, 67, 63, 68, 61, 60, 64, 78, 70, 64, 52, 70, 61, 65, 69, 64, 65, 66, 63, 71, 71, 67, 55, 53, 68, 66, 66, 77, 63, 72, 66, 75, 63, 64, 68, 66, 65, 49, 63, 53, 80, 72, 71, 63, 76, 61, 60, 62, 68, 66, 74, 59, 60, 75, 64, 64, 67, 65, 55, 69, 74, 69, 67, 69, 67, 64, 73, 71, 67, 69, 73, 62, 74, 69, 67, 68, 64, 71, 70, 63, 61, 63] 49.0 73.45 53.0 90.0 [76, 77, 76, 76, 69, 77, 75, 69, 72, 82, 62, 77, 78, 67, 71, 90, 82, 76, 73, 68, 77, 77, 69, 77, 78, 80, 61, 83, 83, 70, 63, 80, 70, 82, 76, 75, 75, 77, 71, 86, 87, 71, 74, 72, 85, 72, 78, 65, 72, 70, 69, 85, 68, 72, 77, 70, 60, 85, 65, 71, 65, 68, 65, 68, 77, 87, 69, 67, 76, 81, 70, 74, 80, 75, 64, 74, 85, 60, 82, 76, 69, 72, 66, 76, 66, 76, 72, 53, 66, 75, 64, 77, 61, 83, 70, 63, 84, 78, 77, 63] 224.0 192.88 173.0 212.0 [200, 203, 189, 190, 183, 188, 201, 204, 209, 173, 202, 192, 191, 195, 188, 185, 180, 187, 191, 197, 195, 188, 201, 194, 190, 175, 204, 184, 197, 191, 208, 190, 193, 188, 191, 191, 196, 183, 193, 178, 189, 209, 190, 195, 182, 185, 191, 194, 193, 187, 202, 183, 196, 194, 190, 212, 208, 193, 189, 188, 195, 201, 192, 202, 196, 183, 195, 202, 181, 192, 204, 182, 191, 193, 200, 194, 191, 202, 178, 187, 197, 191, 199, 192, 193, 185, 193, 210, 194, 194, 193, 186, 204, 181, 198, 199, 178, 191, 195, 206] ESCC SBS17a T>C 929.0 945.0 4830.0 1364.43 1496.71 3866.5 0.2117509541877502 0.5148445639577808 95.295 7035.0 Untranscribed 1.017 1.097 0.927 929.0 1364.43 1278.0 1442.0 [1414, 1342, 1405, 1294, 1387, 1410, 1356, 1339, 1390, 1360, 1356, 1380, 1322, 1353, 1381, 1351, 1359, 1360, 1367, 1339, 1365, 1278, 1341, 1380, 1367, 1339, 1392, 1354, 1365, 1384, 1393, 1365, 1353, 1384, 1379, 1364, 1318, 1333, 1353, 1387, 1360, 1388, 1390, 1333, 1332, 1358, 1320, 1361, 1380, 1359, 1415, 1374, 1361, 1363, 1350, 1388, 1403, 1382, 1325, 1316, 1375, 1318, 1347, 1342, 1406, 1396, 1368, 1371, 1388, 1361, 1381, 1316, 1385, 1384, 1380, 1321, 1328, 1366, 1389, 1352, 1442, 1343, 1371, 1401, 1388, 1380, 1407, 1347, 1415, 1362, 1360, 1316, 1347, 1411, 1384, 1399, 1309, 1373, 1338, 1359] 945.0 1496.71 1421.0 1569.0 [1488, 1553, 1492, 1551, 1514, 1495, 1515, 1498, 1492, 1520, 1502, 1529, 1492, 1493, 1512, 1531, 1488, 1481, 1487, 1513, 1457, 1473, 1532, 1506, 1462, 1490, 1486, 1507, 1485, 1489, 1489, 1479, 1548, 1465, 1492, 1451, 1519, 1507, 1480, 1492, 1499, 1496, 1472, 1548, 1532, 1504, 1527, 1503, 1507, 1462, 1468, 1520, 1501, 1489, 1475, 1430, 1504, 1517, 1517, 1491, 1521, 1508, 1449, 1494, 1477, 1514, 1500, 1446, 1487, 1506, 1498, 1549, 1506, 1554, 1421, 1506, 1465, 1536, 1452, 1494, 1569, 1551, 1500, 1476, 1453, 1469, 1514, 1478, 1480, 1505, 1504, 1507, 1444, 1445, 1515, 1504, 1515, 1493, 1468, 1481] 4830.0 3866.5 3728.0 3975.0 [3824, 3826, 3832, 3876, 3832, 3815, 3867, 3885, 3856, 3854, 3863, 3821, 3909, 3885, 3833, 3849, 3882, 3893, 3880, 3865, 3914, 3975, 3853, 3836, 3900, 3897, 3849, 3858, 3873, 3856, 3857, 3885, 3823, 3881, 3858, 3913, 3890, 3886, 3883, 3843, 3860, 3844, 3863, 3853, 3865, 3872, 3874, 3864, 3843, 3901, 3851, 3838, 3866, 3879, 3900, 3905, 3824, 3825, 3896, 3908, 3830, 3908, 3929, 3896, 3843, 3817, 3858, 3910, 3855, 3855, 3859, 3867, 3841, 3792, 3921, 3892, 3936, 3820, 3889, 3875, 3728, 3839, 3858, 3854, 3891, 3870, 3810, 3901, 3840, 3861, 3862, 3906, 3931, 3878, 3831, 3826, 3899, 3872, 3915, 3877] ESCC SBS17a T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 7035.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Eso-AdenoCA SBS17a C>A 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 411586.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Eso-AdenoCA SBS17a C>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 411586.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Eso-AdenoCA SBS17a C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 411586.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Eso-AdenoCA SBS17a T>A 10753.0 11447.0 58846.0 16551.38 17969.46 46789.85 0.2557910768336743 0.5935718602253292 19.691 411586.0 Untranscribed 1.065 1.086 0.981 10753.0 16551.38 16271.0 16922.0 [16746, 16470, 16526, 16504, 16660, 16654, 16400, 16632, 16737, 16698, 16568, 16506, 16533, 16508, 16654, 16596, 16735, 16648, 16511, 16457, 16663, 16486, 16662, 16308, 16543, 16651, 16580, 16527, 16408, 16646, 16446, 16480, 16634, 16367, 16414, 16529, 16698, 16625, 16587, 16736, 16623, 16381, 16532, 16657, 16579, 16544, 16680, 16568, 16532, 16395, 16705, 16716, 16652, 16271, 16563, 16618, 16350, 16370, 16667, 16519, 16610, 16580, 16456, 16922, 16590, 16543, 16547, 16472, 16523, 16427, 16601, 16580, 16439, 16471, 16666, 16431, 16569, 16746, 16416, 16498, 16572, 16793, 16530, 16667, 16642, 16440, 16528, 16531, 16497, 16495, 16300, 16419, 16378, 16320, 16695, 16402, 16582, 16474, 16675, 16456] 11447.0 17969.46 17672.0 18231.0 [18023, 18013, 17980, 18082, 17987, 18048, 18101, 17872, 17983, 17725, 18048, 17892, 18112, 18043, 18049, 17773, 17909, 17983, 18050, 18090, 17859, 17960, 18044, 18080, 18087, 17797, 17984, 18115, 18007, 17927, 18148, 17958, 18044, 17731, 17931, 18180, 18231, 18032, 17847, 17841, 18100, 17990, 17847, 17889, 18167, 18062, 17828, 17955, 17923, 18003, 17728, 17902, 18071, 18186, 17804, 17985, 18072, 18022, 18012, 18123, 18082, 17769, 17911, 17779, 17996, 17950, 17943, 17965, 17942, 18173, 17889, 17798, 18004, 17914, 17864, 17735, 17904, 18034, 17994, 18177, 17859, 17672, 17984, 17923, 17938, 18020, 17983, 17732, 17854, 18010, 18002, 18169, 18024, 18093, 17751, 17974, 18086, 17970, 17949, 17895] 58846.0 46789.85 46418.0 47215.0 [46554, 46825, 46767, 46752, 46670, 46621, 46778, 46815, 46562, 46888, 46696, 46926, 46678, 46750, 46600, 46966, 46668, 46695, 46804, 46766, 46795, 46883, 46640, 46917, 46658, 46845, 46768, 46661, 46891, 46731, 46720, 46904, 46635, 47215, 46957, 46657, 46418, 46635, 46883, 46767, 46598, 46940, 46917, 46742, 46590, 46686, 46822, 46812, 46863, 46886, 46859, 46676, 46606, 46813, 46958, 46723, 46878, 46911, 46626, 46681, 46607, 46946, 46951, 46637, 46720, 46797, 46799, 46898, 46826, 46713, 46816, 46898, 46862, 46919, 46812, 47139, 46810, 46563, 46859, 46635, 46891, 46819, 46743, 46731, 46723, 46853, 46793, 47053, 46961, 46810, 46993, 46705, 46907, 46890, 46864, 46911, 46636, 46870, 46679, 46998] Eso-AdenoCA SBS17a T>C 43375.0 44851.0 242314.0 67850.88 73347.21 190439.09 2.295362833620771e-07 1.2659783007685861e-06 80.309 411586.0 Untranscribed 1.034 1.081 0.957 43375.0 67850.88 67396.0 68377.0 [67783, 67424, 68129, 67830, 68309, 67548, 67671, 67891, 67877, 67613, 67945, 67948, 67971, 67903, 67893, 67820, 67812, 67973, 68010, 67646, 68074, 68077, 67758, 67602, 67657, 68121, 67883, 67859, 67419, 67620, 67803, 68014, 67781, 67671, 68289, 67871, 67658, 67782, 67769, 67925, 67786, 67843, 67878, 68102, 67877, 67800, 68066, 67948, 68377, 67621, 68099, 67675, 67926, 68064, 67592, 67881, 67588, 67789, 67724, 67603, 67759, 67645, 67502, 67988, 67672, 67856, 67593, 67603, 67688, 68207, 68012, 67905, 68035, 67887, 67798, 68151, 68258, 68032, 68060, 67896, 67953, 67396, 67508, 67830, 67711, 67862, 67820, 67835, 67755, 67917, 67818, 68081, 67508, 67923, 67930, 67875, 68166, 68012, 67950, 67823] 44851.0 73347.21 72858.0 74065.0 [73236, 73600, 73241, 73503, 72992, 73478, 73504, 73256, 73592, 73623, 73477, 73644, 73509, 73485, 73340, 74065, 73219, 73582, 72936, 73491, 73221, 73359, 73355, 73015, 73106, 73354, 73546, 73584, 73173, 73171, 73220, 73103, 73127, 73623, 73629, 73129, 73226, 73079, 73305, 73244, 73633, 73598, 73237, 73086, 73032, 73153, 73462, 73914, 73320, 73453, 73301, 73588, 72858, 73276, 74022, 73137, 73062, 73648, 73747, 73846, 73187, 73143, 73756, 73211, 73109, 72971, 73275, 73537, 73367, 73225, 73238, 73488, 73180, 73202, 73513, 73462, 73007, 73028, 73403, 73272, 73388, 73248, 73417, 73570, 73466, 73247, 73471, 73510, 73720, 73355, 73358, 73044, 73179, 73244, 73161, 72996, 73203, 73512, 73016, 73327] 242314.0 190439.09 189762.0 191125.0 [190622, 190607, 190271, 190311, 190362, 190594, 190462, 190532, 190141, 190431, 190246, 190023, 190148, 190268, 190355, 189803, 190564, 190117, 190687, 190500, 190274, 190157, 190522, 191032, 190810, 190194, 190181, 190220, 191125, 190907, 190668, 190462, 190734, 190337, 189762, 190638, 190786, 190824, 190590, 190456, 190190, 190190, 190506, 190457, 190710, 190689, 190088, 189829, 189993, 190554, 190220, 190362, 190892, 190274, 190003, 190587, 190983, 190154, 190218, 190136, 190737, 190846, 190355, 190448, 190827, 190838, 190753, 190466, 190597, 190220, 190347, 190224, 190400, 190636, 190366, 190006, 190401, 190551, 190135, 190442, 190325, 190975, 190747, 190209, 190470, 190557, 190348, 190323, 190133, 190368, 190446, 190505, 190924, 190400, 190511, 190780, 190270, 190158, 190621, 190486] Eso-AdenoCA SBS17a T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 411586.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Lung-AdenoCA SBS17a C>A 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2540.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Lung-AdenoCA SBS17a C>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2540.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Lung-AdenoCA SBS17a C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2540.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Lung-AdenoCA SBS17a T>A 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2540.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Lung-AdenoCA SBS17a T>C 401.0 411.0 1728.0 515.95 565.47 1465.02 0.4857941690604992 0.9137749508243511 100.0 2540.0 Untranscribed 1.025 1.096 0.935 401.0 515.95 449.0 572.0 [511, 524, 509, 533, 514, 490, 493, 498, 515, 517, 519, 488, 524, 545, 528, 533, 510, 518, 524, 485, 484, 542, 534, 565, 521, 549, 520, 522, 507, 497, 536, 526, 464, 504, 550, 509, 493, 570, 517, 524, 513, 504, 509, 492, 572, 529, 500, 542, 552, 488, 469, 511, 528, 483, 487, 494, 515, 498, 521, 537, 485, 551, 536, 521, 529, 515, 495, 540, 449, 517, 516, 549, 527, 543, 485, 494, 509, 500, 550, 509, 523, 538, 518, 507, 506, 509, 505, 507, 548, 514, 484, 528, 511, 530, 539, 518, 503, 518, 534, 479] 411.0 565.47 503.0 625.0 [573, 556, 553, 503, 586, 581, 592, 557, 567, 566, 589, 602, 589, 587, 582, 522, 592, 532, 579, 568, 573, 546, 582, 564, 565, 559, 556, 588, 554, 569, 573, 553, 546, 567, 555, 564, 560, 531, 563, 587, 534, 548, 590, 565, 566, 548, 565, 551, 579, 593, 579, 558, 542, 563, 625, 560, 567, 562, 583, 531, 558, 574, 527, 552, 565, 579, 566, 531, 593, 557, 598, 550, 539, 583, 566, 564, 568, 588, 555, 557, 549, 545, 570, 556, 574, 576, 581, 546, 569, 588, 567, 547, 583, 601, 512, 542, 573, 563, 579, 616] 1728.0 1465.02 1409.0 1534.0 [1467, 1462, 1480, 1510, 1449, 1477, 1463, 1489, 1461, 1467, 1436, 1459, 1431, 1420, 1435, 1485, 1445, 1496, 1441, 1498, 1485, 1462, 1435, 1414, 1457, 1433, 1466, 1441, 1486, 1477, 1438, 1470, 1534, 1483, 1444, 1467, 1489, 1454, 1465, 1435, 1502, 1493, 1448, 1484, 1409, 1471, 1487, 1460, 1424, 1461, 1504, 1477, 1476, 1503, 1436, 1489, 1462, 1488, 1441, 1485, 1506, 1425, 1486, 1474, 1450, 1456, 1483, 1468, 1502, 1475, 1432, 1450, 1480, 1419, 1495, 1490, 1473, 1454, 1438, 1480, 1473, 1463, 1452, 1480, 1462, 1458, 1460, 1492, 1430, 1451, 1493, 1470, 1458, 1413, 1496, 1484, 1472, 1463, 1437, 1453] Lung-AdenoCA SBS17a T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2540.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Panc-AdenoCA SBS17a C>A 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6970.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Panc-AdenoCA SBS17a C>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6970.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Panc-AdenoCA SBS17a C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6970.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Panc-AdenoCA SBS17a T>A 85.0 94.0 448.0 128.49 137.46 362.22 0.922905368776204 1.0 8.996 6970.0 Untranscribed 1.106 1.07 1.034 85.0 128.49 104.0 156.0 [118, 131, 122, 125, 122, 130, 121, 125, 132, 120, 131, 124, 124, 128, 126, 118, 126, 133, 125, 139, 113, 123, 120, 137, 118, 130, 129, 127, 140, 139, 112, 124, 138, 127, 148, 119, 135, 133, 139, 133, 134, 129, 122, 138, 133, 127, 137, 131, 147, 147, 125, 134, 124, 121, 131, 149, 140, 124, 140, 113, 131, 108, 134, 127, 129, 156, 126, 122, 138, 117, 130, 148, 135, 133, 139, 113, 122, 124, 136, 126, 115, 132, 152, 117, 104, 137, 122, 126, 131, 119, 129, 116, 126, 117, 123, 135, 118, 134, 116, 136] 94.0 137.46 113.0 170.0 [134, 150, 138, 142, 143, 138, 144, 129, 117, 130, 144, 140, 136, 152, 146, 140, 122, 151, 124, 127, 133, 131, 137, 123, 133, 129, 126, 123, 134, 148, 137, 123, 155, 131, 131, 144, 121, 121, 133, 148, 157, 129, 141, 140, 135, 152, 135, 149, 133, 142, 150, 113, 131, 146, 135, 154, 129, 126, 135, 151, 120, 145, 135, 127, 145, 116, 138, 137, 126, 153, 126, 141, 126, 154, 147, 139, 132, 139, 139, 138, 137, 139, 115, 149, 150, 139, 162, 148, 152, 129, 152, 149, 128, 126, 155, 135, 150, 170, 131, 116] 448.0 362.22 324.0 384.0 [376, 347, 366, 361, 362, 358, 366, 371, 377, 378, 355, 367, 371, 352, 354, 370, 378, 345, 378, 362, 384, 374, 372, 367, 379, 368, 374, 376, 353, 342, 378, 379, 336, 369, 350, 367, 372, 374, 354, 344, 335, 368, 365, 353, 359, 351, 358, 348, 345, 342, 353, 382, 372, 362, 362, 324, 360, 378, 355, 362, 378, 376, 365, 373, 355, 359, 366, 368, 365, 358, 373, 341, 366, 342, 345, 378, 372, 366, 355, 363, 379, 357, 364, 363, 371, 351, 343, 353, 345, 379, 348, 363, 375, 383, 350, 357, 359, 324, 379, 375] Panc-AdenoCA SBS17a T>C 873.0 854.0 4616.0 1292.05 1402.09 3666.04 0.09594172233808138 0.27498920301229046 91.004 6970.0 Transcribed 1.022 0.922 1.109 1 873.0 1292.05 1215.0 1394.0 [1334, 1273, 1258, 1298, 1296, 1265, 1297, 1306, 1343, 1336, 1302, 1249, 1258, 1280, 1241, 1219, 1335, 1239, 1273, 1215, 1321, 1288, 1234, 1274, 1285, 1267, 1311, 1277, 1286, 1314, 1331, 1348, 1248, 1306, 1307, 1278, 1320, 1292, 1279, 1283, 1316, 1215, 1290, 1316, 1291, 1247, 1337, 1326, 1259, 1321, 1310, 1303, 1334, 1276, 1344, 1280, 1256, 1277, 1277, 1298, 1228, 1394, 1266, 1274, 1301, 1288, 1238, 1289, 1240, 1291, 1346, 1265, 1315, 1323, 1303, 1302, 1332, 1348, 1323, 1265, 1319, 1284, 1312, 1256, 1352, 1293, 1335, 1298, 1356, 1277, 1298, 1262, 1253, 1280, 1315, 1326, 1297, 1278, 1297, 1247] 854.0 1402.09 1324.0 1484.0 [1382, 1376, 1460, 1389, 1419, 1388, 1423, 1394, 1422, 1373, 1484, 1449, 1364, 1408, 1370, 1477, 1386, 1446, 1458, 1452, 1370, 1389, 1442, 1426, 1406, 1438, 1422, 1403, 1385, 1373, 1385, 1379, 1357, 1450, 1433, 1405, 1390, 1382, 1443, 1378, 1378, 1386, 1383, 1382, 1385, 1436, 1379, 1445, 1369, 1406, 1388, 1347, 1419, 1371, 1395, 1422, 1396, 1376, 1455, 1436, 1410, 1388, 1375, 1390, 1368, 1403, 1417, 1457, 1439, 1431, 1390, 1433, 1324, 1338, 1369, 1389, 1376, 1370, 1384, 1424, 1328, 1450, 1409, 1418, 1386, 1389, 1430, 1421, 1362, 1434, 1389, 1395, 1391, 1399, 1403, 1340, 1416, 1411, 1419, 1414] 4616.0 3666.04 3564.0 3750.0 [3631, 3714, 3651, 3671, 3650, 3705, 3641, 3658, 3597, 3651, 3564, 3662, 3742, 3671, 3750, 3674, 3656, 3674, 3632, 3695, 3677, 3679, 3686, 3653, 3667, 3652, 3629, 3675, 3688, 3679, 3634, 3640, 3746, 3610, 3626, 3677, 3649, 3686, 3642, 3690, 3668, 3750, 3684, 3671, 3682, 3675, 3634, 3600, 3721, 3633, 3664, 3712, 3607, 3710, 3627, 3654, 3702, 3707, 3628, 3627, 3715, 3586, 3722, 3692, 3697, 3666, 3706, 3619, 3686, 3640, 3626, 3654, 3715, 3692, 3692, 3673, 3653, 3635, 3649, 3668, 3723, 3622, 3649, 3684, 3626, 3668, 3604, 3647, 3644, 3637, 3673, 3702, 3716, 3682, 3644, 3696, 3651, 3671, 3651, 3698] Panc-AdenoCA SBS17a T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6970.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS17a C>A 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 179059.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS17a C>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 179059.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS17a C>T 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 179059.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Stomach-AdenoCA SBS17a T>A 5115.0 5580.0 24041.0 7105.87 7703.77 20014.46 0.8093193306220468 1.0 19.399 179059.0 Untranscribed 1.091 1.084 1.006 5115.0 7105.87 6946.0 7306.0 [7003, 7002, 7184, 7061, 7057, 7274, 7103, 7130, 7162, 7025, 7066, 7136, 7067, 7073, 7172, 7091, 7217, 7066, 6954, 7152, 7076, 7189, 7183, 7006, 6947, 7056, 7115, 7149, 7114, 7066, 7093, 7102, 7132, 7189, 7122, 7101, 7118, 7187, 7101, 7038, 7065, 7074, 7158, 7092, 7043, 7198, 7066, 7055, 7061, 7076, 7289, 7147, 7147, 7120, 7097, 7145, 6985, 7159, 7063, 7130, 7033, 7186, 7047, 7079, 7306, 7102, 7133, 7121, 7090, 7034, 7156, 7093, 7035, 7252, 7164, 7129, 7135, 7094, 7064, 7194, 7075, 7197, 6989, 7178, 7016, 7020, 6946, 7061, 6987, 7098, 7136, 7142, 7257, 7122, 7060, 7060, 7186, 7014, 7162, 7185] 5580.0 7703.77 7507.0 7915.0 [7738, 7676, 7597, 7695, 7729, 7638, 7697, 7570, 7721, 7764, 7736, 7620, 7604, 7723, 7507, 7671, 7680, 7838, 7779, 7740, 7799, 7612, 7712, 7745, 7753, 7745, 7736, 7735, 7750, 7547, 7742, 7800, 7790, 7617, 7681, 7712, 7698, 7623, 7763, 7679, 7649, 7713, 7757, 7915, 7756, 7665, 7722, 7716, 7716, 7725, 7657, 7782, 7746, 7773, 7660, 7642, 7687, 7585, 7608, 7656, 7821, 7691, 7723, 7680, 7736, 7625, 7686, 7770, 7897, 7652, 7670, 7599, 7794, 7618, 7629, 7778, 7582, 7726, 7643, 7604, 7717, 7668, 7698, 7699, 7780, 7722, 7761, 7696, 7685, 7841, 7733, 7785, 7594, 7726, 7700, 7630, 7847, 7702, 7765, 7612] 24041.0 20014.46 19794.0 20192.0 [20063, 20136, 20031, 20057, 20034, 19912, 20016, 20135, 19923, 20035, 20015, 20064, 20163, 20043, 20135, 20047, 19927, 19927, 20110, 19915, 19954, 20004, 19949, 20086, 20129, 20015, 19987, 19931, 19962, 20192, 19978, 19932, 19905, 20025, 20028, 19995, 20020, 20011, 19956, 20105, 20102, 20034, 19909, 19830, 20030, 19959, 20023, 20034, 20056, 20018, 19881, 19907, 19940, 19946, 20094, 20041, 20140, 20071, 20138, 20021, 19970, 19942, 20025, 20090, 19794, 20100, 20007, 19918, 19829, 20146, 20014, 20121, 19983, 19966, 20045, 19950, 20099, 20017, 20110, 20031, 20020, 19971, 20143, 19956, 20039, 20079, 20108, 20091, 20155, 19892, 19946, 19899, 19971, 19984, 20065, 20124, 19799, 20083, 19899, 20039] Stomach-AdenoCA SBS17a T>C 20611.0 21593.0 102119.0 29567.13 31996.96 83168.34 0.01044222979520875 0.037678045630796325 80.601 179059.0 Untranscribed 1.048 1.082 0.968 20611.0 29567.13 29253.0 29860.0 [29485, 29540, 29479, 29440, 29426, 29296, 29860, 29636, 29413, 29711, 29505, 29701, 29476, 29611, 29655, 29784, 29483, 29481, 29288, 29438, 29672, 29253, 29438, 29619, 29524, 29656, 29743, 29730, 29622, 29397, 29433, 29790, 29738, 29544, 29514, 29765, 29385, 29671, 29664, 29373, 29529, 29395, 29759, 29502, 29600, 29496, 29526, 29496, 29610, 29459, 29489, 29282, 29609, 29627, 29782, 29632, 29652, 29595, 29505, 29596, 29839, 29691, 29364, 29551, 29495, 29564, 29813, 29592, 29420, 29578, 29336, 29658, 29652, 29540, 29552, 29658, 29710, 29666, 29568, 29359, 29361, 29711, 29546, 29589, 29407, 29514, 29622, 29724, 29673, 29523, 29474, 29563, 29717, 29648, 29695, 29492, 29484, 29618, 29608, 29758] 21593.0 31996.96 31552.0 32363.0 [32069, 31912, 31826, 32091, 31981, 32321, 31779, 32054, 32079, 31915, 32026, 32013, 32059, 32363, 32086, 31784, 31887, 31920, 31965, 32058, 31795, 32245, 31817, 31877, 31938, 31986, 31552, 32116, 32088, 32215, 31875, 31904, 32018, 32071, 32017, 32004, 32030, 32150, 32064, 32022, 31942, 31888, 32009, 31952, 32057, 31991, 32170, 32161, 31932, 32048, 32297, 32244, 31845, 31970, 31999, 32112, 31981, 32073, 32112, 32102, 31841, 31963, 31784, 31920, 31686, 31891, 31918, 31964, 32085, 31868, 31845, 31707, 32041, 32323, 31988, 31831, 31975, 31716, 31885, 32122, 31905, 32095, 32305, 32139, 31723, 32046, 31619, 31979, 32011, 32171, 32056, 32069, 32026, 32022, 31838, 32160, 32270, 31915, 32155, 31982] 102119.0 83168.34 82824.0 83586.0 [83169, 83274, 83409, 83229, 83338, 83117, 83115, 83055, 83249, 83154, 83197, 82993, 83193, 82824, 82977, 83203, 83357, 83378, 83488, 83227, 83295, 83258, 83473, 83201, 83286, 83044, 83429, 82871, 82978, 83127, 83383, 83009, 82997, 83114, 83188, 82976, 83329, 82886, 82994, 83330, 83262, 83433, 82950, 83271, 83023, 83254, 83031, 83087, 83154, 83201, 82985, 83174, 83267, 83161, 82963, 83016, 83111, 83042, 83148, 83003, 83068, 83107, 83551, 83275, 83540, 83300, 82985, 83170, 83201, 83273, 83559, 83358, 83060, 82879, 83199, 83275, 83040, 83320, 83294, 83246, 83478, 82940, 82884, 83063, 83586, 83150, 83494, 83051, 83067, 83014, 83198, 83096, 82981, 83029, 83218, 83118, 82962, 83211, 82966, 82978] Stomach-AdenoCA SBS17a T>G 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 179059.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Summary across all cancer types signature mutation_type strand fold_change_1.1 len(fold_change_1.1_cancer_types) fold_change_1.2 len(fold_change_1.2_cancer_types) fold_change_1.3 len(fold_change_1.3_cancer_types) fold_change_1.5 len(fold_change_1.5_cancer_types) fold_change_1.75 len(fold_change_1.75_cancer_types) fold_change_2+ len(fold_change_2+_cancer_types) all_cancer_types_list len(all_cancer_types_list) avg_fold_change SBS17a T>C Untranscribed [] 0 [] 0 [] 0 [] 0 [] 0 [] 0 ['ESCC', 'Eso-AdenoCA', 'Lung-AdenoCA', 'Panc-AdenoCA', 'Stomach-AdenoCA'] 5