# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	dna_element	encode_element_list	fold_change_list	avg_fold_change	p_value_list	combined_p_value	q_value
SBS17a	ESCC	H3K27ac-human	['ENCFF683MJC_esophagus-squamous-epithelium_Normal_H3K27ac-human']	[0.672]	0.672	[3.4265970100286003e-12]	3.4265970100285962e-12	1.2062250208696995e-11
SBS17a	ESCC	H3K36me3-human	['ENCFF848QKQ_esophagus-squamous-epithelium_Normal_H3K36me3-human']	[0.95]	0.95	[0.001702905795649413]	0.001702905795649413	0.0036039986419783773
SBS17a	ESCC	H3K4me1-human	['ENCFF353HXQ_esophagus-squamous-epithelium_Normal_H3K4me1-human']	[0.878]	0.878	[1.4009373957836387e-09]	1.400937395783637e-09	4.502007359817265e-09
SBS17a	ESCC	H3K4me3-human	['ENCFF518WBH_esophagus-squamous-epithelium_Normal_H3K4me3-human']	[0.642]	0.642	[4.0316160888285035e-11]	4.031616088828502e-11	1.3701781162829906e-10
SBS17a	ESCC	H3K9me3-human	['ENCFF164KXT_esophagus-squamous-epithelium_Normal_H3K9me3-human']	[0.891]	0.891	[0.006019806828640935]	0.00601980682864094	0.011893923172757613
SBS17a	Eso-AdenoCA	H3K27ac-human	['ENCFF720RQS_stomach_Normal_H3K27ac-human', 'ENCFF700ONQ_gastroesophageal-sphincter_Normal_H3K27ac-human']	[0.82, 0.716]	0.768	[5.052957646339556e-100, 0.0]	0.0	0.0
SBS17a	Eso-AdenoCA	H3K27me3-human	['ENCFF647KGZ_stomach_Normal_H3K27me3-human', 'ENCFF503ERU_gastroesophageal-sphincter_Normal_H3K27me3-human']	[0.753, 0.836]	0.794	[4.8561378568436144e-117, 6.04171027393276e-246]	0.0	0.0
SBS17a	Eso-AdenoCA	H3K36me3-human	['ENCFF686JDP_stomach_Normal_H3K36me3-human', 'ENCFF473POV_gastroesophageal-sphincter_Normal_H3K36me3-human']	[0.959, 0.952]	0.955	[5.9545682827803185e-62, 9.799420771084143e-76]	1.8362592147376678e-134	1.8940125287495783e-133
SBS17a	Eso-AdenoCA	H3K4me1-human	['ENCFF324NLX_stomach_Normal_H3K4me1-human', 'ENCFF169EST_gastroesophageal-sphincter_Normal_H3K4me1-human']	[0.882, 0.947]	0.914	[0.0, 1.3154717594213964e-73]	0.0	0.0
SBS17a	Eso-AdenoCA	H3K4me3-human	['ENCFF694HIG_stomach_Normal_H3K4me3-human', 'ENCFF295PRH_gastroesophageal-sphincter_Normal_H3K4me3-human']	[0.831, 0.798]	0.814	[6.488168580052983e-139, 7.435071954522877e-185]	0.0	0.0
SBS17a	Eso-AdenoCA	H3K9me3-human	['ENCFF848XOZ_stomach_Normal_H3K9me3-human', 'ENCFF229CLY_gastroesophageal-sphincter_Normal_H3K9me3-human']	[0.951, 0.957]	0.954	[6.706429405574684e-29, 2.4604123088011812e-20]	1.8319485752777932e-46	1.152325685793589e-45
SBS17a	Lung-AdenoCA	H3K27ac-human	['ENCFF307QJK_upper-lobe-of-left-lung_Normal_H3K27ac-human']	[0.783]	0.783	[0.026306625302715093]	0.02630662530271508	0.04645642967525621
SBS17a	Lung-AdenoCA	H3K4me1-human	['ENCFF712COG_lung_Normal_H3K4me1-human', 'ENCFF433RBT_upper-lobe-of-left-lung_Normal_H3K4me1-human']	[0.931, 0.949]	0.94	[0.12651625659679136, 0.06894490931353597]	0.05008400125025748	0.08311951245555274
SBS17a	Panc-AdenoCA	H3K27ac-human	['ENCFF883GJY_body-of-pancreas_Normal_H3K27ac-human']	[0.827]	0.827	[0.0005420496775920958]	0.0005420496775920961	0.0012205660873948784
SBS17a	Panc-AdenoCA	H3K4me1-human	['ENCFF668HLF_pancreas_Normal_H3K4me1-human', 'ENCFF379TWQ_body-of-pancreas_Normal_H3K4me1-human']	[0.945, 0.932]	0.939	[0.12601928837820245, 0.0005396982404740314]	0.0007206470700974052	0.0015964912286164804
SBS17a	Stomach-AdenoCA	H3K27ac-human	['ENCFF720RQS_stomach_Normal_H3K27ac-human', 'ENCFF700ONQ_gastroesophageal-sphincter_Normal_H3K27ac-human', 'ENCFF152JGG_stomach-smooth-muscle_Normal_H3K27ac-human', 'ENCFF171XOG_duodenal-mucosa_Normal_H3K27ac-human']	[0.821, 0.77, 0.896, 0.905]	0.848	[1.431983720208267e-44, 1.8548654365242917e-107, 8.107513076925074e-17, 6.943927060384197e-08]	1.610041210959353e-167	1.8440979481943394e-166
SBS17a	Stomach-AdenoCA	H3K27me3-human	['ENCFF647KGZ_stomach_Normal_H3K27me3-human', 'ENCFF503ERU_gastroesophageal-sphincter_Normal_H3K27me3-human', 'ENCFF529PGD_stomach-smooth-muscle_Normal_H3K27me3-human', 'ENCFF513YOQ_mucosa-of-stomach_Normal_H3K27me3-human', 'ENCFF780FNE_duodenal-mucosa_Normal_H3K27me3-human']	[0.812, 0.874, 0.929, 0.931, 0.958]	0.901	[5.226162704626489e-45, 6.848778405296788e-62, 2.4706006604383107e-29, 2.6410451340916857e-10, 0.00029016732265902214]	3.767740764639049e-139	3.971654207120888e-138
SBS17a	Stomach-AdenoCA	H3K36me3-human	['ENCFF686JDP_stomach_Normal_H3K36me3-human', 'ENCFF473POV_gastroesophageal-sphincter_Normal_H3K36me3-human', 'ENCFF278MAL_stomach-smooth-muscle_Normal_H3K36me3-human', 'ENCFF485GIB_mucosa-of-stomach_Normal_H3K36me3-human', 'ENCFF569XKN_duodenal-mucosa_Normal_H3K36me3-human']	[0.976, 0.973, 1.024, 1.001, 1.015]	0.998	[9.634522306279968e-12, 7.805956835496008e-11, 1.0555820811261582e-06, 0.8861864295571092, 0.0013594204587684395]	9.646660264606323e-25	4.575307223151355e-24
SBS17a	Stomach-AdenoCA	H3K4me1-human	['ENCFF324NLX_stomach_Normal_H3K4me1-human', 'ENCFF169EST_gastroesophageal-sphincter_Normal_H3K4me1-human', 'ENCFF194BNH_stomach-smooth-muscle_Normal_H3K4me1-human', 'ENCFF190APW_mucosa-of-stomach_Normal_H3K4me1-human', 'ENCFF930IDI_duodenal-mucosa_Normal_H3K4me1-human']	[0.922, 0.956, 0.923, 0.974, 0.971]	0.949	[1.0506112991603586e-131, 3.845424848585945e-21, 5.157336859566367e-39, 2.008896792325235e-07, 2.0715424740470896e-14]	1.9938996406671933e-201	2.483958740662344e-200
SBS17a	Stomach-AdenoCA	H3K4me3-human	['ENCFF694HIG_stomach_Normal_H3K4me3-human', 'ENCFF295PRH_gastroesophageal-sphincter_Normal_H3K4me3-human', 'ENCFF596MVL_stomach-smooth-muscle_Normal_H3K4me3-human', 'ENCFF881KYQ_mucosa-of-stomach_Normal_H3K4me3-human', 'ENCFF091XNE_duodenal-mucosa_Normal_H3K4me3-human']	[0.853, 0.802, 0.821, 1.005, 0.832]	0.862	[1.1012140667106011e-51, 3.0445128823812705e-73, 1.9002801197528664e-49, 0.6120118757200395, 1.8643413008440098e-53]	2.20445173848018e-216	2.8967401782700176e-215
SBS17a	Stomach-AdenoCA	H3K9ac-human	['ENCFF886ETH_stomach-smooth-muscle_Normal_H3K9ac-human', 'ENCFF691STK_mucosa-of-stomach_Normal_H3K9ac-human', 'ENCFF216QZH_duodenal-mucosa_Normal_H3K9ac-human']	[0.858, 0.918, 0.913]	0.896	[1.1642798808397836e-22, 5.634576235705253e-08, 5.510778662619523e-16]	1.930212418343622e-41	1.1482519456099966e-40
SBS17a	Stomach-AdenoCA	H3K9me3-human	['ENCFF848XOZ_stomach_Normal_H3K9me3-human', 'ENCFF229CLY_gastroesophageal-sphincter_Normal_H3K9me3-human', 'ENCFF480IQC_stomach-smooth-muscle_Normal_H3K9me3-human', 'ENCFF738ARH_mucosa-of-stomach_Normal_H3K9me3-human', 'ENCFF036DTV_duodenal-mucosa_Normal_H3K9me3-human']	[0.951, 0.955, 0.967, 1.011, 0.972]	0.971	[2.43267768681027e-16, 1.0415850979474406e-15, 0.0020482534268058566, 0.635912574727501, 0.00031252093171002136]	2.3708397983193816e-31	1.2427475828075775e-30