# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	dna_element	encode_element_list	fold_change_list	avg_fold_change	p_value_list	combined_p_value	q_value
SBS12	Biliary-AdenoCA	H3K27ac-human	['ENCFF285MWK_right-lobe-of-liver_Normal_H3K27ac-human']	[0.921]	0.921	[0.193451034806278]	0.193451034806278	0.26990890475949086
SBS12	Biliary-AdenoCA	H3K4me1-human	['ENCFF323TFF_liver_Normal_H3K4me1-human']	[0.947]	0.947	[0.09728337344309983]	0.09728337344309983	0.14919116862556916
SBS12	ESCC	H3K27ac-human	['ENCFF683MJC_esophagus-squamous-epithelium_Normal_H3K27ac-human']	[0.951]	0.951	[0.21579144772392667]	0.21579144772392664	0.29698414093138686
SBS12	ESCC	H3K36me3-human	['ENCFF848QKQ_esophagus-squamous-epithelium_Normal_H3K36me3-human']	[1.016]	1.016	[0.3712132774733996]	0.3712132774733996	0.4690153585127501
SBS12	ESCC	H3K4me1-human	['ENCFF353HXQ_esophagus-squamous-epithelium_Normal_H3K4me1-human']	[0.981]	0.981	[0.31347882332540955]	0.3134788233254096	0.4078732604610365
SBS12	ESCC	H3K4me3-human	['ENCFF518WBH_esophagus-squamous-epithelium_Normal_H3K4me3-human']	[0.899]	0.899	[0.10247439689265916]	0.10247439689265915	0.15602946860203695
SBS12	ESCC	H3K9me3-human	['ENCFF164KXT_esophagus-squamous-epithelium_Normal_H3K9me3-human']	[0.946]	0.946	[0.13074645354215106]	0.13074645354215106	0.19347248061752165
SBS12	Liver-HCC	H3K27ac-human	['ENCFF752QSK_liver_Normal_H3K27ac-human', 'ENCFF285MWK_right-lobe-of-liver_Normal_H3K27ac-human']	[0.888, 0.903]	0.896	[4.5959788084968855e-06, 2.1017962488354696e-07]	2.7690458907115518e-11	9.461112273072329e-11
SBS12	Liver-HCC	H3K27me3-human	['ENCFF761EPK_liver_Normal_H3K27me3-human']	[0.982]	0.982	[0.11208624330681148]	0.11208624330681151	0.16912108358955397
SBS12	Liver-HCC	H3K36me3-human	['ENCFF597ACD_liver_Normal_H3K36me3-human', 'ENCFF255EYP_right-lobe-of-liver_Normal_H3K36me3-human']	[1.017, 1.0]	1.008	[0.050305119767230365, 0.9851617093293422]	0.1984625770451792	0.2761062030900481
SBS12	Liver-HCC	H3K4me1-human	['ENCFF323TFF_liver_Normal_H3K4me1-human']	[0.992]	0.992	[0.3167650449645897]	0.3167650449645897	0.4110339795499258
SBS12	Liver-HCC	H3K4me3-human	['ENCFF874ZJI_liver_Normal_H3K4me3-human', 'ENCFF250OOO_right-lobe-of-liver_Normal_H3K4me3-human']	[0.921, 0.907]	0.914	[2.268335457686955e-06, 1.282621522430953e-05]	7.349325233984715e-10	2.383716054336378e-09
SBS12	Liver-HCC	H3K9ac-human	['ENCFF332PXX_liver_Normal_H3K9ac-human']	[0.953]	0.953	[0.06049614174526937]	0.060496141745269356	0.09847782699608758
SBS12	Liver-HCC	H3K9me3-human	['ENCFF323VPE_liver_Normal_H3K9me3-human']	[1.006]	1.006	[0.7374608715510169]	0.7374608715510169	0.8100879943147014