# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. # For real mutations on genic (transcribed:T, untranscribed:U and bitranscribed:B) and intergenic (nontranscribed:N) regions averaged across cancer types. MutationType Across_All_Cancer_Types T:A[C>A]A 104.6 U:A[C>A]A 67.6 B:A[C>A]A 0.0 N:A[C>A]A 448.2 T:A[C>A]C 9.4 U:A[C>A]C 4.0 B:A[C>A]C 0.0 N:A[C>A]C 82.4 T:A[C>A]G 2.8 U:A[C>A]G 1.0 B:A[C>A]G 0.0 N:A[C>A]G 23.4 T:A[C>A]T 14.2 U:A[C>A]T 7.6 B:A[C>A]T 0.0 N:A[C>A]T 118.6 T:A[C>G]A 2.8 U:A[C>G]A 1.8 B:A[C>G]A 0.0 N:A[C>G]A 49.8 T:A[C>G]C 0.6 U:A[C>G]C 0.2 B:A[C>G]C 0.0 N:A[C>G]C 16.2 T:A[C>G]G 0.0 U:A[C>G]G 0.0 B:A[C>G]G 0.0 N:A[C>G]G 0.0 T:A[C>G]T 5.4 U:A[C>G]T 8.0 B:A[C>G]T 0.0 N:A[C>G]T 67.8 T:A[C>T]A 73.4 U:A[C>T]A 56.8 B:A[C>T]A 0.0 N:A[C>T]A 303.2 T:A[C>T]C 12.8 U:A[C>T]C 9.2 B:A[C>T]C 0.0 N:A[C>T]C 94.6 T:A[C>T]G 0.0 U:A[C>T]G 0.0 B:A[C>T]G 0.0 N:A[C>T]G 0.2 T:A[C>T]T 20.8 U:A[C>T]T 12.4 B:A[C>T]T 0.0 N:A[C>T]T 117.2 T:A[T>A]A 175.8 U:A[T>A]A 110.0 B:A[T>A]A 0.2 N:A[T>A]A 678.4 T:A[T>A]C 65.2 U:A[T>A]C 35.2 B:A[T>A]C 0.0 N:A[T>A]C 250.0 T:A[T>A]G 68.6 U:A[T>A]G 44.0 B:A[T>A]G 0.0 N:A[T>A]G 285.8 T:A[T>A]T 100.8 U:A[T>A]T 76.8 B:A[T>A]T 0.0 N:A[T>A]T 438.8 T:A[T>C]A 2960.4 U:A[T>C]A 1093.8 B:A[T>C]A 16.8 N:A[T>C]A 5816.2 T:A[T>C]C 1084.4 U:A[T>C]C 530.8 B:A[T>C]C 3.0 N:A[T>C]C 2857.8 T:A[T>C]G 1676.8 U:A[T>C]G 874.6 B:A[T>C]G 7.8 N:A[T>C]G 4348.8 T:A[T>C]T 1807.8 U:A[T>C]T 738.4 B:A[T>C]T 8.2 N:A[T>C]T 3718.0 T:A[T>G]A 40.2 U:A[T>G]A 31.0 B:A[T>G]A 0.0 N:A[T>G]A 178.8 T:A[T>G]C 2.0 U:A[T>G]C 4.0 B:A[T>G]C 0.0 N:A[T>G]C 24.2 T:A[T>G]G 1.0 U:A[T>G]G 0.8 B:A[T>G]G 0.0 N:A[T>G]G 15.2 T:A[T>G]T 16.4 U:A[T>G]T 22.4 B:A[T>G]T 0.0 N:A[T>G]T 90.6 T:C[C>A]A 156.0 U:C[C>A]A 109.4 B:C[C>A]A 0.0 N:C[C>A]A 674.6 T:C[C>A]C 122.0 U:C[C>A]C 81.2 B:C[C>A]C 0.0 N:C[C>A]C 496.8 T:C[C>A]G 9.6 U:C[C>A]G 5.0 B:C[C>A]G 0.0 N:C[C>A]G 49.8 T:C[C>A]T 12.0 U:C[C>A]T 8.4 B:C[C>A]T 0.0 N:C[C>A]T 106.8 T:C[C>G]A 4.2 U:C[C>G]A 3.0 B:C[C>G]A 0.0 N:C[C>G]A 56.4 T:C[C>G]C 0.6 U:C[C>G]C 1.0 B:C[C>G]C 0.0 N:C[C>G]C 16.8 T:C[C>G]G 0.0 U:C[C>G]G 0.0 B:C[C>G]G 0.0 N:C[C>G]G 0.0 T:C[C>G]T 5.0 U:C[C>G]T 10.2 B:C[C>G]T 0.0 N:C[C>G]T 66.8 T:C[C>T]A 161.6 U:C[C>T]A 142.2 B:C[C>T]A 0.0 N:C[C>T]A 592.4 T:C[C>T]C 0.0 U:C[C>T]C 0.0 B:C[C>T]C 0.0 N:C[C>T]C 1.8 T:C[C>T]G 0.0 U:C[C>T]G 0.0 B:C[C>T]G 0.0 N:C[C>T]G 0.0 T:C[C>T]T 73.2 U:C[C>T]T 62.8 B:C[C>T]T 0.0 N:C[C>T]T 290.6 T:C[T>A]A 7.6 U:C[T>A]A 6.0 B:C[T>A]A 0.0 N:C[T>A]A 77.2 T:C[T>A]C 215.8 U:C[T>A]C 160.0 B:C[T>A]C 0.0 N:C[T>A]C 752.6 T:C[T>A]G 42.4 U:C[T>A]G 46.8 B:C[T>A]G 0.0 N:C[T>A]G 195.6 T:C[T>A]T 52.0 U:C[T>A]T 40.8 B:C[T>A]T 0.0 N:C[T>A]T 265.4 T:C[T>C]A 1156.4 U:C[T>C]A 713.6 B:C[T>C]A 5.4 N:C[T>C]A 3579.8 T:C[T>C]C 1395.0 U:C[T>C]C 869.0 B:C[T>C]C 9.2 N:C[T>C]C 4382.0 T:C[T>C]G 761.8 U:C[T>C]G 512.0 B:C[T>C]G 2.8 N:C[T>C]G 2301.6 T:C[T>C]T 1144.0 U:C[T>C]T 776.2 B:C[T>C]T 7.2 N:C[T>C]T 3669.0 T:C[T>G]A 8.4 U:C[T>G]A 6.2 B:C[T>G]A 0.0 N:C[T>G]A 56.2 T:C[T>G]C 9.8 U:C[T>G]C 25.2 B:C[T>G]C 0.0 N:C[T>G]C 60.8 T:C[T>G]G 2.2 U:C[T>G]G 1.6 B:C[T>G]G 0.0 N:C[T>G]G 15.4 T:C[T>G]T 1.0 U:C[T>G]T 1.0 B:C[T>G]T 0.0 N:C[T>G]T 9.0 T:G[C>A]A 28.2 U:G[C>A]A 13.6 B:G[C>A]A 0.0 N:G[C>A]A 144.6 T:G[C>A]C 1.0 U:G[C>A]C 0.2 B:G[C>A]C 0.0 N:G[C>A]C 16.8 T:G[C>A]G 1.0 U:G[C>A]G 0.2 B:G[C>A]G 0.0 N:G[C>A]G 11.6 T:G[C>A]T 0.0 U:G[C>A]T 0.0 B:G[C>A]T 0.0 N:G[C>A]T 0.0 T:G[C>G]A 0.0 U:G[C>G]A 0.2 B:G[C>G]A 0.0 N:G[C>G]A 10.0 T:G[C>G]C 0.0 U:G[C>G]C 0.0 B:G[C>G]C 0.0 N:G[C>G]C 2.2 T:G[C>G]G 0.0 U:G[C>G]G 0.0 B:G[C>G]G 0.0 N:G[C>G]G 0.0 T:G[C>G]T 0.2 U:G[C>G]T 0.0 B:G[C>G]T 0.0 N:G[C>G]T 7.4 T:G[C>T]A 84.4 U:G[C>T]A 76.2 B:G[C>T]A 0.0 N:G[C>T]A 343.4 T:G[C>T]C 12.6 U:G[C>T]C 11.0 B:G[C>T]C 0.0 N:G[C>T]C 86.4 T:G[C>T]G 0.0 U:G[C>T]G 0.0 B:G[C>T]G 0.0 N:G[C>T]G 0.0 T:G[C>T]T 38.2 U:G[C>T]T 33.8 B:G[C>T]T 0.0 N:G[C>T]T 192.2 T:G[T>A]A 4.6 U:G[T>A]A 3.0 B:G[T>A]A 0.0 N:G[T>A]A 63.6 T:G[T>A]C 42.8 U:G[T>A]C 29.2 B:G[T>A]C 0.0 N:G[T>A]C 196.6 T:G[T>A]G 48.4 U:G[T>A]G 38.8 B:G[T>A]G 0.0 N:G[T>A]G 240.6 T:G[T>A]T 7.6 U:G[T>A]T 7.4 B:G[T>A]T 0.0 N:G[T>A]T 100.8 T:G[T>C]A 1788.4 U:G[T>C]A 1182.8 B:G[T>C]A 9.4 N:G[T>C]A 6044.4 T:G[T>C]C 838.8 U:G[T>C]C 520.2 B:G[T>C]C 4.2 N:G[T>C]C 2545.2 T:G[T>C]G 876.8 U:G[T>C]G 660.0 B:G[T>C]G 2.8 N:G[T>C]G 2920.8 T:G[T>C]T 1131.0 U:G[T>C]T 867.0 B:G[T>C]T 4.0 N:G[T>C]T 4135.4 T:G[T>G]A 0.2 U:G[T>G]A 0.2 B:G[T>G]A 0.0 N:G[T>G]A 5.6 T:G[T>G]C 0.0 U:G[T>G]C 0.0 B:G[T>G]C 0.0 N:G[T>G]C 1.6 T:G[T>G]G 0.4 U:G[T>G]G 0.2 B:G[T>G]G 0.0 N:G[T>G]G 7.2 T:G[T>G]T 0.0 U:G[T>G]T 0.0 B:G[T>G]T 0.0 N:G[T>G]T 2.8 T:T[C>A]A 93.4 U:T[C>A]A 74.2 B:T[C>A]A 0.0 N:T[C>A]A 399.2 T:T[C>A]C 71.0 U:T[C>A]C 54.2 B:T[C>A]C 0.0 N:T[C>A]C 306.0 T:T[C>A]G 1.6 U:T[C>A]G 1.2 B:T[C>A]G 0.0 N:T[C>A]G 15.0 T:T[C>A]T 38.8 U:T[C>A]T 39.4 B:T[C>A]T 0.0 N:T[C>A]T 235.2 T:T[C>G]A 4.8 U:T[C>G]A 5.2 B:T[C>G]A 0.0 N:T[C>G]A 59.0 T:T[C>G]C 9.0 U:T[C>G]C 11.6 B:T[C>G]C 0.0 N:T[C>G]C 89.6 T:T[C>G]G 0.0 U:T[C>G]G 0.0 B:T[C>G]G 0.0 N:T[C>G]G 0.8 T:T[C>G]T 47.8 U:T[C>G]T 90.4 B:T[C>G]T 0.0 N:T[C>G]T 271.4 T:T[C>T]A 126.6 U:T[C>T]A 121.0 B:T[C>T]A 0.0 N:T[C>T]A 497.6 T:T[C>T]C 30.2 U:T[C>T]C 29.6 B:T[C>T]C 0.0 N:T[C>T]C 163.0 T:T[C>T]G 0.0 U:T[C>T]G 0.0 B:T[C>T]G 0.0 N:T[C>T]G 0.0 T:T[C>T]T 131.6 U:T[C>T]T 142.8 B:T[C>T]T 0.0 N:T[C>T]T 557.0 T:T[T>A]A 112.2 U:T[T>A]A 94.2 B:T[T>A]A 0.0 N:T[T>A]A 502.4 T:T[T>A]C 268.0 U:T[T>A]C 201.4 B:T[T>A]C 0.0 N:T[T>A]C 1096.4 T:T[T>A]G 57.4 U:T[T>A]G 61.0 B:T[T>A]G 0.0 N:T[T>A]G 320.8 T:T[T>A]T 129.0 U:T[T>A]T 129.4 B:T[T>A]T 0.0 N:T[T>A]T 640.2 T:T[T>C]A 2205.2 U:T[T>C]A 1450.6 B:T[T>C]A 14.8 N:T[T>C]A 7151.8 T:T[T>C]C 1156.2 U:T[T>C]C 793.8 B:T[T>C]C 5.0 N:T[T>C]C 3953.0 T:T[T>C]G 890.4 U:T[T>C]G 697.4 B:T[T>C]G 3.8 N:T[T>C]G 3186.6 T:T[T>C]T 1313.6 U:T[T>C]T 1013.6 B:T[T>C]T 6.6 N:T[T>C]T 4889.0 T:T[T>G]A 18.4 U:T[T>G]A 21.8 B:T[T>G]A 0.0 N:T[T>G]A 110.8 T:T[T>G]C 3.4 U:T[T>G]C 5.2 B:T[T>G]C 0.0 N:T[T>G]C 36.4 T:T[T>G]G 1.4 U:T[T>G]G 1.8 B:T[T>G]G 0.0 N:T[T>G]G 27.8 T:T[T>G]T 29.0 U:T[T>G]T 41.8 B:T[T>G]T 0.2 N:T[T>G]T 128.4 # There must be at least 1000 mutations on the strands. # Signature and mutation type must have at least 5% of all signature mutations on the strands. # Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1. cancer_type signature mutation_type genic_real_count intergenic_real_count genic_mean_sims_count intergenic_mean_sims_count genic_versus_intergenic_p_value genic_versus_intergenic_q_value percentage_of_mutations_on_strands signature_number_of_mutations_on_strands significant_strand FC_REAL FC_SIMS FC fold_change_1.1 fold_change_1.2 fold_change_1.3 fold_change_1.5 fold_change_1.75 fold_change_2+ Transcribed_real_count Transcribed_mean_sims_count Transcribed_min_sims_count Transcribed_max_sims_count Transcribed_sims_count_list UnTranscribed_real_count UnTranscribed_mean_sims_count UnTranscribed_min_sims_count UnTranscribed_max_sims_count UnTranscribed_sims_count_list NonTranscribed_real_count NonTranscribed_mean_sims_count NonTranscribed_min_sims_count NonTranscribed_max_sims_count NonTranscribed_sims_count_list Biliary-AdenoCA SBS12 C>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4070.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Biliary-AdenoCA SBS12 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4070.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Biliary-AdenoCA SBS12 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4070.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Biliary-AdenoCA SBS12 T>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4070.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] Biliary-AdenoCA SBS12 T>C 1316.0 2754.0 1736.79 2344.6 1.5616924049702764e-21 1.3441497234249119e-20 100.0 4070.0 Intergenic 2.093 1.35 1.55 1 1 1 1 795.0 818.61 745.0 883.0 [797.0, 841.0, 824.0, 835.0, 842.0, 773.0, 832.0, 844.0, 834.0, 809.0, 801.0, 832.0, 808.0, 851.0, 788.0, 863.0, 816.0, 809.0, 814.0, 811.0, 789.0, 796.0, 847.0, 838.0, 837.0, 804.0, 815.0, 831.0, 807.0, 845.0, 810.0, 784.0, 828.0, 804.0, 837.0, 823.0, 817.0, 842.0, 795.0, 745.0, 849.0, 819.0, 789.0, 831.0, 789.0, 839.0, 839.0, 809.0, 803.0, 824.0, 790.0, 773.0, 829.0, 800.0, 883.0, 768.0, 804.0, 808.0, 813.0, 816.0, 844.0, 818.0, 829.0, 879.0, 810.0, 836.0, 801.0, 781.0, 812.0, 824.0, 796.0, 820.0, 856.0, 838.0, 821.0, 768.0, 873.0, 818.0, 844.0, 800.0, 829.0, 797.0, 774.0, 812.0, 855.0, 830.0, 828.0, 816.0, 808.0, 838.0, 800.0, 825.0, 862.0, 839.0, 814.0, 807.0, 814.0, 810.0, 812.0, 830.0] 521.0 918.18 849.0 995.0 [918.0, 940.0, 953.0, 918.0, 895.0, 951.0, 898.0, 957.0, 938.0, 911.0, 870.0, 933.0, 935.0, 903.0, 906.0, 891.0, 924.0, 935.0, 927.0, 958.0, 901.0, 894.0, 849.0, 939.0, 939.0, 862.0, 932.0, 902.0, 916.0, 915.0, 911.0, 918.0, 919.0, 911.0, 893.0, 871.0, 975.0, 910.0, 872.0, 914.0, 928.0, 928.0, 940.0, 911.0, 917.0, 886.0, 896.0, 912.0, 901.0, 977.0, 919.0, 995.0, 904.0, 930.0, 925.0, 950.0, 915.0, 913.0, 894.0, 921.0, 951.0, 930.0, 898.0, 886.0, 933.0, 930.0, 879.0, 925.0, 942.0, 902.0, 927.0, 908.0, 928.0, 936.0, 907.0, 923.0, 865.0, 923.0, 928.0, 945.0, 929.0, 910.0, 969.0, 897.0, 889.0, 887.0, 903.0, 922.0, 914.0, 923.0, 937.0, 955.0, 865.0, 913.0, 943.0, 917.0, 909.0, 921.0, 931.0, 952.0] 2754.0 2344.6 2274.0 2425.0 [2361.0, 2304.0, 2306.0, 2329.0, 2347.0, 2359.0, 2346.0, 2284.0, 2307.0, 2363.0, 2406.0, 2313.0, 2335.0, 2330.0, 2392.0, 2330.0, 2344.0, 2343.0, 2337.0, 2313.0, 2387.0, 2392.0, 2386.0, 2307.0, 2309.0, 2417.0, 2333.0, 2344.0, 2353.0, 2322.0, 2353.0, 2386.0, 2332.0, 2373.0, 2346.0, 2382.0, 2295.0, 2339.0, 2417.0, 2425.0, 2303.0, 2338.0, 2348.0, 2340.0, 2372.0, 2353.0, 2345.0, 2360.0, 2372.0, 2289.0, 2376.0, 2319.0, 2351.0, 2353.0, 2274.0, 2362.0, 2361.0, 2359.0, 2367.0, 2339.0, 2292.0, 2337.0, 2353.0, 2315.0, 2336.0, 2320.0, 2402.0, 2367.0, 2336.0, 2353.0, 2356.0, 2360.0, 2298.0, 2303.0, 2352.0, 2393.0, 2340.0, 2338.0, 2304.0, 2336.0, 2323.0, 2373.0, 2340.0, 2368.0, 2334.0, 2366.0, 2354.0, 2349.0, 2354.0, 2327.0, 2343.0, 2303.0, 2356.0, 2329.0, 2328.0, 2355.0, 2355.0, 2357.0, 2332.0, 2295.0] Biliary-AdenoCA SBS12 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 4070.0 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] 0.0 0.0 0.0 0.0 [0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0] ESCC SBS12 C>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS12 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS12 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS12 T>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] ESCC SBS12 T>C 2776.0 4187.0 2963.86 3999.87 0.0012840772995175054 0.0052312031585606805 100.0 6963.0 Intergenic 1.508 1.35 1.118 1 1318.0 1412.94 1337.0 1482.0 [1417, 1371, 1436, 1431, 1442, 1412, 1374, 1418, 1477, 1403, 1423, 1482, 1427, 1430, 1361, 1398, 1469, 1437, 1364, 1473, 1405, 1375, 1391, 1401, 1410, 1380, 1393, 1447, 1447, 1443, 1430, 1354, 1400, 1387, 1415, 1351, 1440, 1381, 1431, 1433, 1397, 1447, 1448, 1445, 1461, 1384, 1393, 1445, 1457, 1474, 1444, 1419, 1337, 1365, 1413, 1472, 1435, 1411, 1378, 1403, 1350, 1441, 1407, 1392, 1406, 1432, 1463, 1374, 1357, 1452, 1389, 1376, 1432, 1442, 1379, 1414, 1409, 1481, 1367, 1407, 1358, 1391, 1424, 1409, 1399, 1390, 1381, 1432, 1386, 1400, 1460, 1352, 1424, 1420, 1428, 1371, 1440, 1410, 1439, 1423] 1458.0 1550.92 1444.0 1631.0 [1549, 1521, 1497, 1563, 1491, 1544, 1539, 1586, 1535, 1613, 1481, 1529, 1575, 1516, 1574, 1529, 1566, 1536, 1589, 1543, 1584, 1566, 1589, 1539, 1589, 1589, 1601, 1538, 1562, 1493, 1538, 1585, 1505, 1579, 1555, 1593, 1559, 1629, 1589, 1584, 1554, 1514, 1505, 1444, 1488, 1575, 1540, 1564, 1546, 1548, 1548, 1576, 1631, 1550, 1500, 1562, 1523, 1569, 1566, 1614, 1572, 1547, 1575, 1567, 1611, 1544, 1554, 1526, 1587, 1604, 1479, 1491, 1559, 1557, 1444, 1552, 1570, 1519, 1573, 1557, 1518, 1578, 1541, 1538, 1597, 1565, 1523, 1519, 1536, 1594, 1556, 1562, 1550, 1515, 1532, 1503, 1559, 1563, 1579, 1517] 4187.0 3999.87 3905.0 4133.0 [4003, 4068, 4032, 3965, 4033, 4005, 4054, 3958, 3960, 3951, 4067, 3945, 3958, 4013, 4023, 4032, 3929, 3986, 4015, 3957, 3979, 4023, 3982, 4026, 3962, 3998, 3976, 3987, 3956, 4030, 4001, 4029, 4056, 3991, 3998, 4016, 3968, 3959, 3944, 3957, 4011, 4002, 4012, 4067, 4022, 4016, 4033, 3955, 3957, 3937, 3974, 3966, 3999, 4059, 4054, 3937, 4002, 3978, 4017, 3942, 4031, 3973, 3984, 4009, 3952, 3983, 3946, 4063, 4017, 3905, 4091, 4097, 3975, 3976, 4133, 3993, 3978, 3958, 4028, 3999, 4075, 3985, 3996, 4011, 3982, 3997, 4064, 4008, 4050, 3976, 3945, 4050, 3983, 4030, 4004, 4089, 3967, 3993, 3940, 4019] ESCC SBS12 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 6963.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Kidney-RCC SBS12 C>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2251.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Kidney-RCC SBS12 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2251.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Kidney-RCC SBS12 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2251.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Kidney-RCC SBS12 T>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2251.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Kidney-RCC SBS12 T>C 814.0 1437.0 971.11 1283.98 2.317348007192309e-06 1.1963613444166416e-05 100.0 2251.0 Intergenic 1.765 1.322 1.335 1 1 1 529.0 456.67 410.0 500.0 [470, 441, 459, 459, 460, 467, 438, 483, 452, 442, 441, 461, 423, 452, 476, 497, 455, 485, 468, 472, 473, 454, 426, 428, 500, 495, 465, 420, 442, 452, 443, 452, 452, 424, 463, 442, 455, 476, 476, 466, 427, 479, 454, 453, 464, 447, 469, 427, 472, 453, 447, 444, 456, 450, 463, 449, 465, 477, 478, 432, 490, 458, 459, 452, 451, 465, 456, 471, 431, 410, 477, 457, 459, 476, 438, 458, 463, 463, 440, 460, 455, 462, 421, 432, 458, 462, 455, 447, 458, 466, 449, 458, 445, 471, 450, 450, 465, 465, 491, 462] 285.0 514.44 457.0 571.0 [524, 529, 496, 514, 512, 512, 527, 508, 502, 457, 510, 538, 522, 525, 521, 473, 473, 522, 472, 541, 522, 503, 507, 519, 525, 497, 515, 536, 501, 496, 558, 518, 566, 542, 529, 525, 520, 498, 542, 496, 556, 562, 512, 489, 497, 504, 521, 528, 505, 488, 502, 522, 511, 483, 527, 524, 486, 511, 521, 521, 518, 514, 526, 521, 504, 539, 507, 527, 555, 552, 545, 520, 537, 528, 519, 534, 507, 509, 493, 503, 489, 497, 571, 508, 500, 518, 518, 498, 517, 459, 529, 475, 506, 477, 524, 507, 485, 512, 523, 510] 1437.0 1283.98 1212.0 1356.0 [1261, 1289, 1298, 1284, 1282, 1276, 1290, 1262, 1300, 1356, 1301, 1265, 1309, 1275, 1259, 1288, 1323, 1246, 1314, 1241, 1259, 1297, 1318, 1305, 1231, 1267, 1280, 1297, 1313, 1306, 1261, 1288, 1235, 1286, 1268, 1279, 1275, 1280, 1236, 1293, 1269, 1212, 1284, 1319, 1292, 1304, 1269, 1305, 1274, 1318, 1304, 1290, 1288, 1321, 1265, 1290, 1306, 1264, 1260, 1299, 1250, 1284, 1272, 1280, 1300, 1250, 1292, 1258, 1269, 1292, 1235, 1280, 1260, 1250, 1298, 1262, 1285, 1282, 1317, 1286, 1316, 1294, 1267, 1315, 1298, 1280, 1283, 1309, 1285, 1328, 1276, 1322, 1300, 1307, 1282, 1296, 1301, 1283, 1239, 1289] Kidney-RCC SBS12 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 2251.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS12 C>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 55289.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS12 C>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 55289.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS12 C>T 0.0 0.0 0.0 0.0 1.0 1.0 0.0 55289.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS12 T>A 0.0 0.0 0.0 0.0 1.0 1.0 0.0 55289.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Liver-HCC SBS12 T>C 19192.0 36097.0 23664.17 31730.85 8.021012946454799e-165 1.9535661057733984e-163 100.0 55289.0 Intergenic 1.881 1.341 1.403 1 1 1 11707.0 11347.75 11100.0 11530.0 [11378, 11361, 11288, 11425, 11228, 11396, 11365, 11256, 11484, 11305, 11309, 11416, 11444, 11288, 11381, 11322, 11483, 11365, 11351, 11239, 11289, 11361, 11362, 11441, 11334, 11459, 11295, 11100, 11454, 11462, 11263, 11426, 11198, 11392, 11374, 11289, 11288, 11389, 11205, 11525, 11279, 11368, 11399, 11405, 11359, 11395, 11293, 11350, 11319, 11389, 11216, 11449, 11422, 11511, 11525, 11298, 11282, 11302, 11341, 11199, 11412, 11457, 11436, 11267, 11413, 11343, 11361, 11324, 11421, 11387, 11530, 11408, 11120, 11519, 11288, 11229, 11387, 11294, 11361, 11301, 11342, 11311, 11281, 11440, 11286, 11324, 11400, 11186, 11260, 11393, 11370, 11207, 11288, 11319, 11346, 11413, 11259, 11297, 11333, 11371] 7485.0 12316.42 11966.0 12575.0 [12288, 12282, 12318, 12289, 12137, 12362, 12332, 12375, 12298, 12256, 12309, 12308, 12252, 12250, 12272, 12514, 12308, 12346, 12324, 12314, 12094, 12144, 12273, 12120, 12318, 12380, 12317, 12256, 12185, 12497, 12340, 12242, 12362, 12414, 12373, 12485, 12244, 12127, 12439, 12109, 12316, 12278, 12437, 12260, 12356, 12255, 12329, 12247, 12357, 12381, 12340, 12397, 12338, 12163, 12276, 12374, 12383, 12319, 12252, 12294, 12340, 12305, 12280, 12447, 12524, 12374, 12575, 12399, 12512, 12417, 12245, 12433, 12333, 12294, 12139, 12258, 12235, 12337, 12349, 12376, 12355, 12354, 12368, 12361, 12306, 12353, 12228, 12245, 12294, 12253, 12214, 12449, 12395, 12425, 12417, 11966, 12179, 12356, 12401, 12346] 36097.0 31730.85 31422.0 32037.0 [31731, 31762, 31784, 31657, 32006, 31661, 31686, 31766, 31591, 31826, 31795, 31674, 31681, 31835, 31752, 31557, 31607, 31703, 31717, 31840, 31985, 31885, 31784, 31836, 31750, 31568, 31801, 32037, 31758, 31422, 31794, 31738, 31849, 31582, 31673, 31610, 31857, 31842, 31760, 31773, 31785, 31774, 31531, 31725, 31692, 31722, 31790, 31840, 31703, 31641, 31857, 31560, 31605, 31704, 31603, 31752, 31723, 31770, 31817, 31898, 31653, 31639, 31658, 31660, 31480, 31681, 31460, 31667, 31473, 31620, 31611, 31585, 31951, 31579, 31941, 31910, 31774, 31760, 31685, 31722, 31699, 31736, 31727, 31615, 31820, 31719, 31769, 31947, 31828, 31742, 31808, 31726, 31724, 31628, 31632, 32007, 31939, 31735, 31670, 31678] Liver-HCC SBS12 T>G 0.0 0.0 0.0 0.0 1.0 1.0 0.0 55289.0 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] 0.0 0.0 0.0 0.0 [0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0] Summary across all cancer types signature mutation_type strand fold_change_1.1 len(fold_change_1.1_cancer_types) fold_change_1.2 len(fold_change_1.2_cancer_types) fold_change_1.3 len(fold_change_1.3_cancer_types) fold_change_1.5 len(fold_change_1.5_cancer_types) fold_change_1.75 len(fold_change_1.75_cancer_types) fold_change_2+ len(fold_change_2+_cancer_types) all_cancer_types_list len(all_cancer_types_list) avg_fold_change SBS12 T>C Intergenic ['Biliary-AdenoCA', 'ESCC', 'Kidney-RCC', 'Liver-HCC'] 4 ['Biliary-AdenoCA', 'Kidney-RCC', 'Liver-HCC'] 3 ['Biliary-AdenoCA', 'Kidney-RCC', 'Liver-HCC'] 3 ['Biliary-AdenoCA'] 1 [] 0 [] 0 ['Biliary-AdenoCA', 'ESCC', 'Kidney-RCC', 'Liver-HCC'] 4 1.3