# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
signature	cancer_type	dna_element	encode_element_list	fold_change_list	avg_fold_change	p_value_list	combined_p_value	q_value
SBS11	CNS-GBM	H3K27ac-human	['ENCFF569CXZ_temporal-lobe_Normal_H3K27ac-human', 'ENCFF683NWP_caudate-nucleus_Normal_H3K27ac-human', 'ENCFF244CUD_layer-of-hippocampus_Normal_H3K27ac-human', 'ENCFF580NGD_cingulate-gyrus_Normal_H3K27ac-human', 'ENCFF794OTB_angular-gyrus_Normal_H3K27ac-human', 'ENCFF794VMY_astrocyte_Normal_H3K27ac-human', 'ENCFF783KFR_substantia-nigra_Normal_H3K27ac-human']	[0.986, 0.984, 0.979, 0.981, 0.983, 0.995, 0.977]	0.984	[0.008031014289275063, 0.05597118835604831, 0.0032511619851384264, 0.0027309826344337922, 0.038156830949429815, 0.5894981010257605, 0.015121994484201075]	9.939492708811264e-07	2.7656151938875137e-06
SBS11	CNS-GBM	H3K27me3-human	['ENCFF454FZP_temporal-lobe_Normal_H3K27me3-human', 'ENCFF124CRU_caudate-nucleus_Normal_H3K27me3-human', 'ENCFF045MDR_layer-of-hippocampus_Normal_H3K27me3-human', 'ENCFF738KDZ_cingulate-gyrus_Normal_H3K27me3-human', 'ENCFF016YZC_angular-gyrus_Normal_H3K27me3-human', 'ENCFF741YLR_brain_Normal_H3K27me3-human', 'ENCFF368WBE_substantia-nigra_Normal_H3K27me3-human', 'ENCFF998XPL_germinal-matrix_Normal_H3K27me3-human']	[0.985, 0.995, 0.981, 0.985, 0.991, 0.997, 0.997, 1.005]	0.992	[0.07059358787873235, 0.46045762809310053, 0.01971147581735346, 0.06738874982400883, 0.226102964692936, 0.6473166239635215, 0.73369497753902, 0.5780420573423195]	0.05901498851786652	0.09648083124970339
SBS11	CNS-GBM	H3K36me3-human	['ENCFF973EHB_temporal-lobe_Normal_H3K36me3-human', 'ENCFF537NSQ_caudate-nucleus_Normal_H3K36me3-human', 'ENCFF658PCF_layer-of-hippocampus_Normal_H3K36me3-human', 'ENCFF110DNE_cingulate-gyrus_Normal_H3K36me3-human', 'ENCFF224NZD_angular-gyrus_Normal_H3K36me3-human', 'ENCFF713YWB_brain_Normal_H3K36me3-human', 'ENCFF043CJJ_substantia-nigra_Normal_H3K36me3-human', 'ENCFF863DFK_germinal-matrix_Normal_H3K36me3-human']	[1.008, 1.0, 0.999, 1.0, 0.998, 0.994, 0.997, 0.997]	0.999	[0.21407943596043433, 0.926665498174849, 0.8847748694218229, 0.9441709919766716, 0.6379061061897744, 0.03590440665751494, 0.6524734731485016, 0.32689837552927303]	0.5809897780120779	0.6722731538698259
SBS11	CNS-GBM	H3K4me1-human	['ENCFF269CDZ_temporal-lobe_Normal_H3K4me1-human', 'ENCFF674XMP_caudate-nucleus_Normal_H3K4me1-human', 'ENCFF985VDO_layer-of-hippocampus_Normal_H3K4me1-human', 'ENCFF607MLZ_cingulate-gyrus_Normal_H3K4me1-human', 'ENCFF782USE_angular-gyrus_Normal_H3K4me1-human', 'ENCFF488ELW_brain_Normal_H3K4me1-human', 'ENCFF619ILT_substantia-nigra_Normal_H3K4me1-human', 'ENCFF729RTM_germinal-matrix_Normal_H3K4me1-human']	[0.999, 0.99, 1.0, 1.001, 1.001, 0.999, 0.998, 0.996]	0.998	[0.8921458343516059, 0.008368153916027537, 0.9620520488218123, 0.6805208381223564, 0.8630035505387823, 0.6260883297949253, 0.5407457317587046, 0.33957662839314773]	0.505467871298126	0.6002724302602629
SBS11	CNS-GBM	H3K4me3-human	['ENCFF125RCN_temporal-lobe_Normal_H3K4me3-human', 'ENCFF955VMY_caudate-nucleus_Normal_H3K4me3-human', 'ENCFF992CFR_layer-of-hippocampus_Normal_H3K4me3-human', 'ENCFF310HBQ_cingulate-gyrus_Normal_H3K4me3-human', 'ENCFF770ZSA_angular-gyrus_Normal_H3K4me3-human', 'ENCFF827EAA_astrocyte-of-the-cerebellum_Normal_H3K4me3-human', 'ENCFF483PRQ_brain_Normal_H3K4me3-human', 'ENCFF082IAX_choroid-plexus-epithelial-cell_Normal_H3K4me3-human', 'ENCFF552LZP_astrocyte_Normal_H3K4me3-human', 'ENCFF938RRM_cerebellum_Normal_H3K4me3-human', 'ENCFF225GLV_substantia-nigra_Normal_H3K4me3-human', 'ENCFF524OEP_germinal-matrix_Normal_H3K4me3-human']	[0.98, 0.97, 0.986, 0.986, 0.98, 0.998, 0.991, 0.997, 0.976, 0.98, 0.983, 0.992]	0.985	[0.04165365145502702, 0.000710209277372943, 0.14225030591392848, 0.09532366609884112, 0.028217740353110362, 0.808913483854222, 0.21689244581250144, 0.746592198220257, 0.006182688187652893, 0.005536918073244905, 0.053261812287868214, 0.27047222855954334]	2.4242843894781224e-06	6.625341312270338e-06
SBS11	CNS-GBM	H3K9ac-human	['ENCFF698IEA_temporal-lobe_Normal_H3K9ac-human', 'ENCFF030MBV_caudate-nucleus_Normal_H3K9ac-human', 'ENCFF359DCF_layer-of-hippocampus_Normal_H3K9ac-human', 'ENCFF475OYF_cingulate-gyrus_Normal_H3K9ac-human', 'ENCFF432PJF_angular-gyrus_Normal_H3K9ac-human', 'ENCFF160APM_astrocyte_Normal_H3K9ac-human', 'ENCFF340IAY_substantia-nigra_Normal_H3K9ac-human']	[0.965, 0.98, 0.972, 0.982, 0.98, 0.97, 0.972]	0.975	[8.442838032104955e-06, 0.005004336355949088, 0.0001918764531870449, 0.012391921511465181, 0.014732787605641827, 0.002569852533555158, 0.0003027692354881849]	2.2871289042389226e-14	8.578410171617543e-14
SBS11	CNS-GBM	H3K9me3-human	['ENCFF231NBP_temporal-lobe_Normal_H3K9me3-human', 'ENCFF819MHP_caudate-nucleus_Normal_H3K9me3-human', 'ENCFF662HYS_layer-of-hippocampus_Normal_H3K9me3-human', 'ENCFF802EAD_cingulate-gyrus_Normal_H3K9me3-human', 'ENCFF996GCW_angular-gyrus_Normal_H3K9me3-human', 'ENCFF013EFU_brain_Normal_H3K9me3-human', 'ENCFF355UPU_substantia-nigra_Normal_H3K9me3-human', 'ENCFF197DHO_germinal-matrix_Normal_H3K9me3-human']	[1.002, 1.01, 1.007, 1.007, 1.002, 0.992, 0.995, 0.976]	0.999	[0.7703957634201577, 0.2514180588135717, 0.4434788320158758, 0.5212997030764657, 0.7686348078844457, 0.11952981360331294, 0.6947984018614017, 0.00045387689368660023]	0.04027289024805196	0.06834457314541148
SBS11	CNS-GBM	H4K20me1-human	['ENCFF148ART_astrocyte_Normal_H4K20me1-human']	[1.0]	1.0	[0.9682822281445708]	0.9682822281445708	0.9789983950963684