# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered.
# For real mutations on genic (transcribed:T, untranscribed:U and bitranscribed:B) and intergenic (nontranscribed:N) regions averaged across cancer types.
MutationType	Across_All_Cancer_Types
T:A[C>A]A	32.0
U:A[C>A]A	29.0
B:A[C>A]A	0.0
N:A[C>A]A	178.0
T:A[C>A]C	153.0
U:A[C>A]C	128.0
B:A[C>A]C	1.0
N:A[C>A]C	633.0
T:A[C>A]G	1.0
U:A[C>A]G	1.0
B:A[C>A]G	0.0
N:A[C>A]G	7.0
T:A[C>A]T	131.0
U:A[C>A]T	123.0
B:A[C>A]T	0.0
N:A[C>A]T	632.0
T:A[C>G]A	2.0
U:A[C>G]A	2.0
B:A[C>G]A	0.0
N:A[C>G]A	6.0
T:A[C>G]C	1.0
U:A[C>G]C	2.0
B:A[C>G]C	0.0
N:A[C>G]C	6.0
T:A[C>G]G	0.0
U:A[C>G]G	0.0
B:A[C>G]G	0.0
N:A[C>G]G	0.0
T:A[C>G]T	4.0
U:A[C>G]T	3.0
B:A[C>G]T	0.0
N:A[C>G]T	12.0
T:A[C>T]A	63.0
U:A[C>T]A	49.0
B:A[C>T]A	0.0
N:A[C>T]A	235.0
T:A[C>T]C	61.0
U:A[C>T]C	54.0
B:A[C>T]C	0.0
N:A[C>T]C	209.0
T:A[C>T]G	160.0
U:A[C>T]G	142.0
B:A[C>T]G	0.0
N:A[C>T]G	469.0
T:A[C>T]T	76.0
U:A[C>T]T	70.0
B:A[C>T]T	0.0
N:A[C>T]T	267.0
T:A[T>A]A	69.0
U:A[T>A]A	57.0
B:A[T>A]A	0.0
N:A[T>A]A	288.0
T:A[T>A]C	170.0
U:A[T>A]C	143.0
B:A[T>A]C	0.0
N:A[T>A]C	664.0
T:A[T>A]G	5.0
U:A[T>A]G	5.0
B:A[T>A]G	0.0
N:A[T>A]G	48.0
T:A[T>A]T	704.0
U:A[T>A]T	740.0
B:A[T>A]T	3.0
N:A[T>A]T	3487.0
T:A[T>C]A	154.0
U:A[T>C]A	132.0
B:A[T>C]A	0.0
N:A[T>C]A	607.0
T:A[T>C]C	103.0
U:A[T>C]C	88.0
B:A[T>C]C	0.0
N:A[T>C]C	392.0
T:A[T>C]G	101.0
U:A[T>C]G	88.0
B:A[T>C]G	0.0
N:A[T>C]G	407.0
T:A[T>C]T	100.0
U:A[T>C]T	97.0
B:A[T>C]T	0.0
N:A[T>C]T	438.0
T:A[T>G]A	40.0
U:A[T>G]A	40.0
B:A[T>G]A	0.0
N:A[T>G]A	208.0
T:A[T>G]C	7.0
U:A[T>G]C	6.0
B:A[T>G]C	0.0
N:A[T>G]C	35.0
T:A[T>G]G	3.0
U:A[T>G]G	3.0
B:A[T>G]G	0.0
N:A[T>G]G	21.0
T:A[T>G]T	122.0
U:A[T>G]T	139.0
B:A[T>G]T	0.0
N:A[T>G]T	580.0
T:C[C>A]A	187.0
U:C[C>A]A	171.0
B:C[C>A]A	0.0
N:C[C>A]A	862.0
T:C[C>A]C	90.0
U:C[C>A]C	61.0
B:C[C>A]C	0.0
N:C[C>A]C	343.0
T:C[C>A]G	8.0
U:C[C>A]G	6.0
B:C[C>A]G	0.0
N:C[C>A]G	53.0
T:C[C>A]T	552.0
U:C[C>A]T	469.0
B:C[C>A]T	2.0
N:C[C>A]T	2552.0
T:C[C>G]A	0.0
U:C[C>G]A	0.0
B:C[C>G]A	0.0
N:C[C>G]A	1.0
T:C[C>G]C	0.0
U:C[C>G]C	0.0
B:C[C>G]C	0.0
N:C[C>G]C	1.0
T:C[C>G]G	0.0
U:C[C>G]G	0.0
B:C[C>G]G	0.0
N:C[C>G]G	1.0
T:C[C>G]T	1.0
U:C[C>G]T	1.0
B:C[C>G]T	0.0
N:C[C>G]T	3.0
T:C[C>T]A	49.0
U:C[C>T]A	49.0
B:C[C>T]A	0.0
N:C[C>T]A	192.0
T:C[C>T]C	79.0
U:C[C>T]C	73.0
B:C[C>T]C	0.0
N:C[C>T]C	258.0
T:C[C>T]G	101.0
U:C[C>T]G	101.0
B:C[C>T]G	1.0
N:C[C>T]G	294.0
T:C[C>T]T	118.0
U:C[C>T]T	121.0
B:C[C>T]T	0.0
N:C[C>T]T	431.0
T:C[T>A]A	13.0
U:C[T>A]A	12.0
B:C[T>A]A	0.0
N:C[T>A]A	82.0
T:C[T>A]C	20.0
U:C[T>A]C	21.0
B:C[T>A]C	0.0
N:C[T>A]C	111.0
T:C[T>A]G	7.0
U:C[T>A]G	6.0
B:C[T>A]G	0.0
N:C[T>A]G	47.0
T:C[T>A]T	34.0
U:C[T>A]T	34.0
B:C[T>A]T	0.0
N:C[T>A]T	213.0
T:C[T>C]A	102.0
U:C[T>C]A	98.0
B:C[T>C]A	0.0
N:C[T>C]A	458.0
T:C[T>C]C	104.0
U:C[T>C]C	87.0
B:C[T>C]C	0.0
N:C[T>C]C	435.0
T:C[T>C]G	99.0
U:C[T>C]G	102.0
B:C[T>C]G	0.0
N:C[T>C]G	418.0
T:C[T>C]T	172.0
U:C[T>C]T	198.0
B:C[T>C]T	0.0
N:C[T>C]T	853.0
T:C[T>G]A	219.0
U:C[T>G]A	181.0
B:C[T>G]A	2.0
N:C[T>G]A	843.0
T:C[T>G]C	13.0
U:C[T>G]C	13.0
B:C[T>G]C	0.0
N:C[T>G]C	79.0
T:C[T>G]G	96.0
U:C[T>G]G	90.0
B:C[T>G]G	1.0
N:C[T>G]G	375.0
T:C[T>G]T	303.0
U:C[T>G]T	330.0
B:C[T>G]T	1.0
N:C[T>G]T	1475.0
T:G[C>A]A	91.0
U:G[C>A]A	93.0
B:G[C>A]A	0.0
N:G[C>A]A	427.0
T:G[C>A]C	69.0
U:G[C>A]C	63.0
B:G[C>A]C	0.0
N:G[C>A]C	277.0
T:G[C>A]G	1.0
U:G[C>A]G	1.0
B:G[C>A]G	0.0
N:G[C>A]G	10.0
T:G[C>A]T	155.0
U:G[C>A]T	160.0
B:G[C>A]T	0.0
N:G[C>A]T	766.0
T:G[C>G]A	1.0
U:G[C>G]A	1.0
B:G[C>G]A	0.0
N:G[C>G]A	3.0
T:G[C>G]C	3.0
U:G[C>G]C	3.0
B:G[C>G]C	0.0
N:G[C>G]C	12.0
T:G[C>G]G	0.0
U:G[C>G]G	0.0
B:G[C>G]G	0.0
N:G[C>G]G	0.0
T:G[C>G]T	1.0
U:G[C>G]T	2.0
B:G[C>G]T	0.0
N:G[C>G]T	3.0
T:G[C>T]A	45.0
U:G[C>T]A	40.0
B:G[C>T]A	0.0
N:G[C>T]A	167.0
T:G[C>T]C	124.0
U:G[C>T]C	123.0
B:G[C>T]C	2.0
N:G[C>T]C	390.0
T:G[C>T]G	157.0
U:G[C>T]G	161.0
B:G[C>T]G	1.0
N:G[C>T]G	460.0
T:G[C>T]T	186.0
U:G[C>T]T	195.0
B:G[C>T]T	2.0
N:G[C>T]T	562.0
T:G[T>A]A	19.0
U:G[T>A]A	24.0
B:G[T>A]A	0.0
N:G[T>A]A	111.0
T:G[T>A]C	68.0
U:G[T>A]C	71.0
B:G[T>A]C	0.0
N:G[T>A]C	298.0
T:G[T>A]G	12.0
U:G[T>A]G	16.0
B:G[T>A]G	0.0
N:G[T>A]G	73.0
T:G[T>A]T	117.0
U:G[T>A]T	128.0
B:G[T>A]T	0.0
N:G[T>A]T	583.0
T:G[T>C]A	158.0
U:G[T>C]A	176.0
B:G[T>C]A	0.0
N:G[T>C]A	642.0
T:G[T>C]C	128.0
U:G[T>C]C	122.0
B:G[T>C]C	0.0
N:G[T>C]C	473.0
T:G[T>C]G	127.0
U:G[T>C]G	138.0
B:G[T>C]G	1.0
N:G[T>C]G	489.0
T:G[T>C]T	139.0
U:G[T>C]T	173.0
B:G[T>C]T	1.0
N:G[T>C]T	617.0
T:G[T>G]A	3.0
U:G[T>G]A	3.0
B:G[T>G]A	0.0
N:G[T>G]A	19.0
T:G[T>G]C	5.0
U:G[T>G]C	7.0
B:G[T>G]C	0.0
N:G[T>G]C	34.0
T:G[T>G]G	4.0
U:G[T>G]G	6.0
B:G[T>G]G	0.0
N:G[T>G]G	28.0
T:G[T>G]T	147.0
U:G[T>G]T	182.0
B:G[T>G]T	2.0
N:G[T>G]T	670.0
T:T[C>A]A	618.0
U:T[C>A]A	584.0
B:T[C>A]A	2.0
N:T[C>A]A	3080.0
T:T[C>A]C	57.0
U:T[C>A]C	60.0
B:T[C>A]C	0.0
N:T[C>A]C	264.0
T:T[C>A]G	11.0
U:T[C>A]G	11.0
B:T[C>A]G	0.0
N:T[C>A]G	67.0
T:T[C>A]T	1560.0
U:T[C>A]T	1676.0
B:T[C>A]T	9.0
N:T[C>A]T	8167.0
T:T[C>G]A	1.0
U:T[C>G]A	1.0
B:T[C>G]A	0.0
N:T[C>G]A	3.0
T:T[C>G]C	2.0
U:T[C>G]C	2.0
B:T[C>G]C	0.0
N:T[C>G]C	6.0
T:T[C>G]G	0.0
U:T[C>G]G	0.0
B:T[C>G]G	0.0
N:T[C>G]G	0.0
T:T[C>G]T	1.0
U:T[C>G]T	1.0
B:T[C>G]T	0.0
N:T[C>G]T	5.0
T:T[C>T]A	21.0
U:T[C>T]A	20.0
B:T[C>T]A	0.0
N:T[C>T]A	98.0
T:T[C>T]C	116.0
U:T[C>T]C	113.0
B:T[C>T]C	0.0
N:T[C>T]C	419.0
T:T[C>T]G	86.0
U:T[C>T]G	99.0
B:T[C>T]G	0.0
N:T[C>T]G	272.0
T:T[C>T]T	168.0
U:T[C>T]T	195.0
B:T[C>T]T	1.0
N:T[C>T]T	695.0
T:T[T>A]A	251.0
U:T[T>A]A	292.0
B:T[T>A]A	4.0
N:T[T>A]A	966.0
T:T[T>A]C	12.0
U:T[T>A]C	13.0
B:T[T>A]C	0.0
N:T[T>A]C	90.0
T:T[T>A]G	1.0
U:T[T>A]G	4.0
B:T[T>A]G	0.0
N:T[T>A]G	25.0
T:T[T>A]T	48.0
U:T[T>A]T	60.0
B:T[T>A]T	0.0
N:T[T>A]T	262.0
T:T[T>C]A	159.0
U:T[T>C]A	167.0
B:T[T>C]A	0.0
N:T[T>C]A	687.0
T:T[T>C]C	260.0
U:T[T>C]C	328.0
B:T[T>C]C	2.0
N:T[T>C]C	1087.0
T:T[T>C]G	104.0
U:T[T>C]G	135.0
B:T[T>C]G	0.0
N:T[T>C]G	505.0
T:T[T>C]T	231.0
U:T[T>C]T	305.0
B:T[T>C]T	1.0
N:T[T>C]T	1147.0
T:T[T>G]A	166.0
U:T[T>G]A	155.0
B:T[T>G]A	1.0
N:T[T>G]A	711.0
T:T[T>G]C	2.0
U:T[T>G]C	3.0
B:T[T>G]C	0.0
N:T[T>G]C	21.0
T:T[T>G]G	4.0
U:T[T>G]G	9.0
B:T[T>G]G	0.0
N:T[T>G]G	46.0
T:T[T>G]T	316.0
U:T[T>G]T	376.0
B:T[T>G]T	1.0
N:T[T>G]T	1579.0

# There must be at least 1000 mutations on the strands.
# Signature and mutation type must have at least 5% of all signature mutations on the strands.
# Odds ratio between fold change of real mutations and fold change of simulated mutations must be at least 1.1.
cancer_type	signature	mutation_type	genic_real_count	intergenic_real_count	genic_mean_sims_count	intergenic_mean_sims_count	genic_versus_intergenic_p_value	genic_versus_intergenic_q_value	percentage_of_mutations_on_strands	signature_number_of_mutations_on_strands	significant_strand	FC_REAL	FC_SIMS	FC	fold_change_1.1	fold_change_1.2	fold_change_1.3	fold_change_1.5	fold_change_1.75	fold_change_2+	Transcribed_real_count	Transcribed_mean_sims_count	Transcribed_min_sims_count	Transcribed_max_sims_count	Transcribed_sims_count_list	UnTranscribed_real_count	UnTranscribed_mean_sims_count	UnTranscribed_min_sims_count	UnTranscribed_max_sims_count	UnTranscribed_sims_count_list	NonTranscribed_real_count	NonTranscribed_mean_sims_count	NonTranscribed_min_sims_count	NonTranscribed_max_sims_count	NonTranscribed_sims_count_list
Lymph-BNHL	SBS10c	C>A	4478.0	11176.0	6438.56	9262.11	5.760665059517828e-118	1.1361479203771548e-116	73.763	21222.0	Intergenic	2.496	1.439	1.735	1	1	1	1			2205.0	3114.95	3019.0	3251.0	[3103.0, 3079.0, 3128.0, 3125.0, 3125.0, 3043.0, 3028.0, 3074.0, 3033.0, 3136.0, 3158.0, 3140.0, 3120.0, 3085.0, 3120.0, 3117.0, 3132.0, 3094.0, 3090.0, 3084.0, 3090.0, 3050.0, 3138.0, 3163.0, 3095.0, 3196.0, 3065.0, 3126.0, 3181.0, 3069.0, 3085.0, 3147.0, 3094.0, 3203.0, 3019.0, 3094.0, 3137.0, 3206.0, 3178.0, 3130.0, 3056.0, 3185.0, 3075.0, 3086.0, 3163.0, 3096.0, 3070.0, 3132.0, 3117.0, 3166.0, 3105.0, 3104.0, 3065.0, 3091.0, 3095.0, 3036.0, 3106.0, 3112.0, 3156.0, 3174.0, 3082.0, 3204.0, 3066.0, 3125.0, 3060.0, 3051.0, 3114.0, 3085.0, 3114.0, 3139.0, 3154.0, 3192.0, 3068.0, 3147.0, 3104.0, 3075.0, 3145.0, 3142.0, 3246.0, 3098.0, 3103.0, 3085.0, 3130.0, 3090.0, 3118.0, 3114.0, 3165.0, 3118.0, 3251.0, 3114.0, 3023.0, 3160.0, 3122.0, 3086.0, 3106.0, 3155.0, 3134.0, 3090.0, 3167.0, 3083.0]	2273.0	3323.61	3167.0	3413.0	[3325.0, 3324.0, 3238.0, 3351.0, 3349.0, 3337.0, 3401.0, 3396.0, 3385.0, 3334.0, 3363.0, 3350.0, 3342.0, 3167.0, 3258.0, 3211.0, 3409.0, 3374.0, 3323.0, 3328.0, 3334.0, 3299.0, 3318.0, 3344.0, 3326.0, 3339.0, 3374.0, 3413.0, 3279.0, 3299.0, 3278.0, 3243.0, 3346.0, 3334.0, 3386.0, 3252.0, 3317.0, 3342.0, 3239.0, 3328.0, 3340.0, 3285.0, 3373.0, 3304.0, 3332.0, 3383.0, 3352.0, 3202.0, 3361.0, 3238.0, 3269.0, 3341.0, 3336.0, 3271.0, 3291.0, 3306.0, 3363.0, 3310.0, 3295.0, 3270.0, 3339.0, 3367.0, 3347.0, 3338.0, 3368.0, 3331.0, 3333.0, 3299.0, 3284.0, 3316.0, 3277.0, 3387.0, 3300.0, 3318.0, 3306.0, 3367.0, 3357.0, 3258.0, 3310.0, 3338.0, 3370.0, 3356.0, 3345.0, 3306.0, 3362.0, 3232.0, 3317.0, 3356.0, 3233.0, 3323.0, 3315.0, 3321.0, 3383.0, 3375.0, 3335.0, 3321.0, 3347.0, 3383.0, 3260.0, 3404.0]	11176.0	9262.11	9118.0	9447.0	[9285.0, 9298.0, 9322.0, 9242.0, 9225.0, 9310.0, 9275.0, 9225.0, 9285.0, 9234.0, 9179.0, 9219.0, 9248.0, 9447.0, 9306.0, 9367.0, 9160.0, 9226.0, 9281.0, 9290.0, 9288.0, 9359.0, 9235.0, 9186.0, 9268.0, 9174.0, 9271.0, 9157.0, 9239.0, 9334.0, 9333.0, 9316.0, 9260.0, 9164.0, 9305.0, 9358.0, 9262.0, 9156.0, 9280.0, 9256.0, 9289.0, 9233.0, 9261.0, 9295.0, 9203.0, 9226.0, 9285.0, 9368.0, 9212.0, 9294.0, 9321.0, 9265.0, 9309.0, 9338.0, 9306.0, 9350.0, 9234.0, 9260.0, 9275.0, 9254.0, 9278.0, 9128.0, 9294.0, 9241.0, 9277.0, 9324.0, 9240.0, 9299.0, 9302.0, 9243.0, 9276.0, 9118.0, 9341.0, 9249.0, 9284.0, 9246.0, 9203.0, 9294.0, 9145.0, 9256.0, 9223.0, 9249.0, 9232.0, 9318.0, 9213.0, 9357.0, 9221.0, 9219.0, 9229.0, 9258.0, 9357.0, 9223.0, 9203.0, 9237.0, 9258.0, 9230.0, 9219.0, 9233.0, 9265.0, 9226.0]
Lymph-BNHL	SBS10c	C>G	0.0	0.0	0.0	0.0	1.0	1.0	0.0	21222.0											0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]	0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]	0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]
Lymph-BNHL	SBS10c	C>T	0.0	0.0	0.0	0.0	1.0	1.0	0.0	21222.0											0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]	0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]	0.0	0.0	0.0	0.0	[0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0]
Lymph-BNHL	SBS10c	T>A	1529.0	3672.0	2092.56	3120.17	1.0717415384132374e-30	1.0775579293245548e-29	24.508	21222.0	Intergenic	2.402	1.491	1.611	1	1	1	1			743.0	997.86	919.0	1055.0	[998.0, 1006.0, 1045.0, 999.0, 1001.0, 976.0, 966.0, 1024.0, 977.0, 1003.0, 1011.0, 1043.0, 969.0, 996.0, 999.0, 975.0, 975.0, 981.0, 1004.0, 1000.0, 997.0, 950.0, 972.0, 1045.0, 1006.0, 983.0, 1049.0, 988.0, 1009.0, 946.0, 1005.0, 1007.0, 970.0, 1028.0, 976.0, 1016.0, 1028.0, 972.0, 1036.0, 989.0, 1017.0, 1045.0, 1013.0, 984.0, 1026.0, 1015.0, 1015.0, 980.0, 987.0, 968.0, 949.0, 1014.0, 990.0, 1049.0, 963.0, 1022.0, 965.0, 1028.0, 1012.0, 1001.0, 986.0, 970.0, 1006.0, 1051.0, 990.0, 985.0, 999.0, 1006.0, 964.0, 1023.0, 957.0, 1019.0, 979.0, 1014.0, 1035.0, 986.0, 963.0, 1028.0, 1014.0, 979.0, 985.0, 1005.0, 1008.0, 1021.0, 953.0, 1002.0, 998.0, 919.0, 1002.0, 983.0, 1038.0, 997.0, 1055.0, 969.0, 1024.0, 968.0, 1004.0, 954.0, 1054.0, 930.0]	786.0	1094.7	1038.0	1155.0	[1044.0, 1097.0, 1094.0, 1075.0, 1081.0, 1150.0, 1122.0, 1066.0, 1077.0, 1081.0, 1131.0, 1080.0, 1065.0, 1110.0, 1094.0, 1133.0, 1090.0, 1100.0, 1071.0, 1114.0, 1053.0, 1082.0, 1087.0, 1113.0, 1105.0, 1121.0, 1098.0, 1054.0, 1057.0, 1104.0, 1085.0, 1110.0, 1076.0, 1122.0, 1111.0, 1082.0, 1084.0, 1092.0, 1081.0, 1071.0, 1077.0, 1113.0, 1119.0, 1085.0, 1059.0, 1105.0, 1099.0, 1094.0, 1085.0, 1120.0, 1072.0, 1078.0, 1051.0, 1093.0, 1134.0, 1125.0, 1038.0, 1112.0, 1064.0, 1088.0, 1143.0, 1108.0, 1121.0, 1094.0, 1078.0, 1045.0, 1141.0, 1155.0, 1109.0, 1063.0, 1080.0, 1075.0, 1091.0, 1086.0, 1050.0, 1040.0, 1144.0, 1086.0, 1101.0, 1145.0, 1098.0, 1079.0, 1126.0, 1107.0, 1150.0, 1098.0, 1107.0, 1075.0, 1129.0, 1087.0, 1147.0, 1126.0, 1104.0, 1089.0, 1046.0, 1117.0, 1113.0, 1053.0, 1088.0, 1102.0]	3672.0	3120.17	3033.0	3215.0	[3171.0, 3109.0, 3069.0, 3137.0, 3124.0, 3087.0, 3122.0, 3125.0, 3161.0, 3133.0, 3068.0, 3092.0, 3176.0, 3108.0, 3117.0, 3103.0, 3153.0, 3125.0, 3134.0, 3102.0, 3163.0, 3187.0, 3157.0, 3068.0, 3099.0, 3106.0, 3068.0, 3174.0, 3136.0, 3166.0, 3118.0, 3102.0, 3160.0, 3063.0, 3130.0, 3118.0, 3104.0, 3143.0, 3093.0, 3152.0, 3122.0, 3055.0, 3084.0, 3142.0, 3129.0, 3090.0, 3101.0, 3132.0, 3142.0, 3124.0, 3189.0, 3120.0, 3174.0, 3078.0, 3116.0, 3060.0, 3203.0, 3078.0, 3133.0, 3119.0, 3080.0, 3135.0, 3087.0, 3071.0, 3151.0, 3180.0, 3071.0, 3054.0, 3141.0, 3128.0, 3171.0, 3114.0, 3138.0, 3118.0, 3140.0, 3184.0, 3098.0, 3095.0, 3101.0, 3088.0, 3133.0, 3136.0, 3081.0, 3080.0, 3114.0, 3112.0, 3110.0, 3215.0, 3071.0, 3140.0, 3033.0, 3090.0, 3061.0, 3161.0, 3148.0, 3121.0, 3093.0, 3199.0, 3076.0, 3184.0]
Lymph-BNHL	SBS10c	T>C	34.0	55.0	35.31	54.05	1.0	1.0	0.419	21222.0	Intergenic	1.618	1.531	1.057							16.0	15.55	7.0	26.0	[14.0, 18.0, 13.0, 17.0, 13.0, 18.0, 11.0, 23.0, 17.0, 17.0, 12.0, 15.0, 17.0, 22.0, 14.0, 12.0, 9.0, 15.0, 12.0, 17.0, 14.0, 13.0, 12.0, 21.0, 18.0, 15.0, 14.0, 11.0, 19.0, 17.0, 12.0, 10.0, 12.0, 17.0, 13.0, 11.0, 20.0, 13.0, 9.0, 23.0, 12.0, 18.0, 14.0, 16.0, 17.0, 16.0, 12.0, 17.0, 17.0, 18.0, 15.0, 16.0, 18.0, 13.0, 10.0, 7.0, 19.0, 19.0, 16.0, 13.0, 13.0, 16.0, 20.0, 15.0, 12.0, 19.0, 13.0, 14.0, 20.0, 13.0, 18.0, 25.0, 13.0, 14.0, 18.0, 18.0, 13.0, 17.0, 16.0, 11.0, 11.0, 21.0, 15.0, 18.0, 15.0, 19.0, 17.0, 17.0, 23.0, 16.0, 10.0, 18.0, 16.0, 21.0, 11.0, 19.0, 9.0, 12.0, 20.0, 26.0]	18.0	19.76	9.0	33.0	[17.0, 17.0, 20.0, 13.0, 21.0, 17.0, 30.0, 24.0, 17.0, 17.0, 18.0, 22.0, 21.0, 18.0, 18.0, 14.0, 26.0, 21.0, 18.0, 20.0, 16.0, 26.0, 15.0, 24.0, 13.0, 20.0, 20.0, 27.0, 14.0, 24.0, 22.0, 24.0, 24.0, 21.0, 19.0, 18.0, 20.0, 19.0, 24.0, 12.0, 16.0, 26.0, 19.0, 20.0, 20.0, 24.0, 26.0, 18.0, 23.0, 20.0, 19.0, 18.0, 18.0, 19.0, 25.0, 27.0, 19.0, 13.0, 18.0, 30.0, 20.0, 18.0, 32.0, 23.0, 24.0, 24.0, 22.0, 13.0, 17.0, 18.0, 20.0, 17.0, 20.0, 17.0, 17.0, 16.0, 21.0, 19.0, 20.0, 17.0, 15.0, 18.0, 17.0, 20.0, 25.0, 21.0, 22.0, 20.0, 20.0, 14.0, 19.0, 33.0, 9.0, 16.0, 13.0, 19.0, 19.0, 26.0, 15.0, 11.0]	55.0	54.05	37.0	65.0	[58.0, 55.0, 56.0, 59.0, 55.0, 54.0, 50.0, 44.0, 55.0, 56.0, 59.0, 52.0, 51.0, 50.0, 58.0, 63.0, 54.0, 53.0, 59.0, 53.0, 59.0, 50.0, 63.0, 44.0, 58.0, 55.0, 56.0, 52.0, 56.0, 48.0, 55.0, 55.0, 53.0, 51.0, 57.0, 60.0, 49.0, 57.0, 56.0, 55.0, 61.0, 46.0, 56.0, 53.0, 52.0, 50.0, 51.0, 54.0, 49.0, 51.0, 56.0, 55.0, 56.0, 57.0, 54.0, 55.0, 51.0, 57.0, 55.0, 47.0, 57.0, 56.0, 37.0, 51.0, 53.0, 47.0, 54.0, 62.0, 53.0, 58.0, 51.0, 47.0, 56.0, 59.0, 55.0, 55.0, 56.0, 53.0, 54.0, 61.0, 63.0, 50.0, 57.0, 52.0, 49.0, 50.0, 50.0, 53.0, 48.0, 59.0, 61.0, 38.0, 64.0, 52.0, 65.0, 51.0, 61.0, 51.0, 54.0, 53.0]
Lymph-BNHL	SBS10c	T>G	74.0	204.0	112.69	166.44	0.0008583314826680085	0.0035701156001586914	1.31	21222.0	Intergenic	2.757	1.477	1.866	1	1	1	1	1		38.0	54.97	36.0	71.0	[49.0, 57.0, 54.0, 49.0, 49.0, 54.0, 55.0, 54.0, 60.0, 64.0, 49.0, 56.0, 47.0, 56.0, 68.0, 50.0, 59.0, 49.0, 57.0, 53.0, 59.0, 63.0, 48.0, 51.0, 49.0, 51.0, 62.0, 50.0, 62.0, 50.0, 48.0, 57.0, 36.0, 63.0, 53.0, 59.0, 57.0, 52.0, 53.0, 65.0, 54.0, 52.0, 71.0, 71.0, 57.0, 56.0, 62.0, 61.0, 56.0, 50.0, 60.0, 51.0, 54.0, 60.0, 53.0, 50.0, 68.0, 61.0, 46.0, 53.0, 64.0, 51.0, 51.0, 43.0, 57.0, 40.0, 59.0, 70.0, 48.0, 53.0, 55.0, 54.0, 52.0, 59.0, 61.0, 54.0, 54.0, 57.0, 44.0, 54.0, 53.0, 64.0, 63.0, 46.0, 60.0, 45.0, 62.0, 62.0, 47.0, 43.0, 65.0, 47.0, 49.0, 46.0, 49.0, 63.0, 61.0, 58.0, 47.0, 64.0]	36.0	57.72	43.0	73.0	[64.0, 62.0, 61.0, 66.0, 61.0, 69.0, 73.0, 66.0, 57.0, 64.0, 62.0, 63.0, 54.0, 59.0, 50.0, 58.0, 57.0, 50.0, 61.0, 49.0, 53.0, 52.0, 55.0, 60.0, 54.0, 51.0, 54.0, 57.0, 53.0, 68.0, 59.0, 64.0, 70.0, 53.0, 50.0, 48.0, 55.0, 48.0, 53.0, 51.0, 73.0, 54.0, 51.0, 53.0, 60.0, 64.0, 63.0, 43.0, 69.0, 57.0, 62.0, 63.0, 61.0, 54.0, 62.0, 53.0, 55.0, 55.0, 64.0, 63.0, 59.0, 63.0, 52.0, 62.0, 55.0, 63.0, 58.0, 47.0, 54.0, 61.0, 61.0, 61.0, 54.0, 51.0, 45.0, 51.0, 55.0, 62.0, 55.0, 48.0, 56.0, 57.0, 48.0, 66.0, 59.0, 47.0, 58.0, 56.0, 65.0, 66.0, 49.0, 66.0, 66.0, 61.0, 57.0, 58.0, 59.0, 55.0, 52.0, 61.0]	204.0	166.44	151.0	187.0	[166.0, 159.0, 165.0, 165.0, 168.0, 157.0, 152.0, 160.0, 163.0, 151.0, 168.0, 161.0, 181.0, 163.0, 160.0, 172.0, 164.0, 181.0, 163.0, 176.0, 166.0, 163.0, 178.0, 167.0, 177.0, 176.0, 163.0, 172.0, 164.0, 161.0, 171.0, 159.0, 172.0, 165.0, 175.0, 172.0, 166.0, 179.0, 173.0, 163.0, 152.0, 173.0, 157.0, 156.0, 162.0, 158.0, 158.0, 174.0, 154.0, 172.0, 156.0, 167.0, 164.0, 165.0, 165.0, 175.0, 156.0, 165.0, 170.0, 164.0, 157.0, 164.0, 175.0, 175.0, 168.0, 177.0, 162.0, 162.0, 177.0, 165.0, 164.0, 165.0, 172.0, 169.0, 174.0, 173.0, 171.0, 159.0, 180.0, 176.0, 170.0, 158.0, 169.0, 167.0, 159.0, 187.0, 159.0, 160.0, 168.0, 169.0, 165.0, 165.0, 163.0, 171.0, 172.0, 157.0, 159.0, 167.0, 179.0, 155.0]

Summary across all cancer types
signature	mutation_type	strand	fold_change_1.1	len(fold_change_1.1_cancer_types)	fold_change_1.2	len(fold_change_1.2_cancer_types)	fold_change_1.3	len(fold_change_1.3_cancer_types)	fold_change_1.5	len(fold_change_1.5_cancer_types)	fold_change_1.75	len(fold_change_1.75_cancer_types)	fold_change_2+	len(fold_change_2+_cancer_types)	all_cancer_types_list	len(all_cancer_types_list)	avg_fold_change
SBS10c	C>A	Intergenic	['Lymph-BNHL']	1	['Lymph-BNHL']	1	['Lymph-BNHL']	1	['Lymph-BNHL']	1	[]	0	[]	0	['Lymph-BNHL']	1	1.5
SBS10c	T>A	Intergenic	['Lymph-BNHL']	1	['Lymph-BNHL']	1	['Lymph-BNHL']	1	['Lymph-BNHL']	1	[]	0	[]	0	['Lymph-BNHL']	1	1.5