# Only cancer types with minimum 2000 mutations for SBS signatures and minimum 1000 mutations for DBS and ID signatures with average probability at least 0.75 are considered. signature cancer_type cutoff number_of_mutations average_probability file_name pearson_corr pearson_p_value pearson_q_value real_average_number_of_overlaps sims_average_number_of_overlaps avg_real_signal sim_data_avg_signal fold_change real_average_signal_array sims_average_signal_array SBS10c Lymph-BNHL 0.63 21195 0.755 SBS10c_ENCFF449NOT_B-cell_Normal_CTCF-human_AverageSignalArray.txt 1.0 0.0 0.0 49.59 113.618 166.066 180.651 0.919 [196.198, 196.198, 196.198, 196.198, 197.359, 200.948, 195.774, 195.774, 195.774, 186.098, 186.098, 186.098, 185.563, 185.563, 185.563, 184.006, 184.006, 184.006, 184.006, 184.223, 184.223, 184.223, 184.223, 184.223, 184.223, 182.782, 182.782, 182.782, 185.187, 185.187, 185.187, 185.685, 185.685, 185.685, 185.685, 187.026, 187.026, 187.026, 187.026, 191.026, 191.026, 191.026, 191.026, 194.702, 194.702, 194.702, 194.702, 192.639, 192.639, 192.639, 192.639, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 185.786, 187.344, 187.344, 187.344, 187.344, 187.344, 187.344, 187.344, 187.344, 187.344, 182.427, 182.427, 182.427, 182.427, 182.427, 185.237, 185.237, 185.237, 185.237, 185.237, 185.237, 185.237, 187.231, 187.231, 187.231, 187.231, 187.231, 184.08, 184.08, 184.08, 184.08, 184.08, 184.08, 184.08, 182.128, 182.128, 182.128, 182.128, 182.128, 182.128, 182.128, 187.519, 187.519, 184.636, 184.636, 184.636, 184.636, 181.84, 181.997, 181.997, 181.997, 181.997, 181.997, 181.997, 181.997, 181.997, 184.948, 187.331, 187.331, 187.331, 187.331, 187.331, 187.331, 182.551, 182.551, 182.551, 182.551, 187.248, 187.248, 187.248, 187.248, 187.248, 187.248, 187.248, 187.874, 187.874, 187.874, 187.874, 187.874, 189.645, 189.645, 189.645, 190.389, 190.552, 183.875, 183.54, 183.54, 186.605, 181.991, 181.991, 181.991, 181.991, 181.991, 181.991, 181.991, 183.773, 183.773, 186.42, 186.42, 186.42, 186.42, 185.983, 185.983, 185.983, 184.279, 184.279, 181.301, 179.429, 179.429, 179.429, 182.459, 182.459, 182.459, 182.459, 179.682, 179.682, 179.682, 179.682, 177.06, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.03, 180.42, 180.42, 180.42, 183.099, 186.402, 186.402, 186.402, 183.26, 183.26, 184.823, 188.084, 188.084, 188.084, 187.476, 181.501, 181.501, 181.501, 181.501, 181.501, 181.501, 181.501, 181.501, 181.501, 181.501, 184.962, 184.962, 184.962, 184.962, 184.962, 184.962, 184.962, 184.962, 181.811, 181.811, 181.811, 181.811, 181.811, 181.811, 181.811, 181.811, 181.811, 180.944, 180.944, 181.797, 181.797, 181.797, 181.797, 181.797, 180.366, 180.366, 180.366, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 183.551, 184.895, 189.375, 189.375, 189.375, 189.375, 189.375, 192.707, 192.707, 181.526, 181.526, 181.526, 184.581, 181.388, 181.388, 181.388, 179.783, 179.783, 179.783, 176.691, 176.691, 176.691, 176.691, 176.691, 176.691, 176.691, 176.691, 176.691, 176.691, 174.98, 174.98, 174.98, 174.98, 174.98, 176.753, 176.753, 176.753, 176.753, 168.499, 168.499, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 169.951, 172.439, 172.439, 172.439, 172.439, 172.439, 172.439, 171.017, 171.017, 165.291, 165.291, 161.401, 161.401, 157.618, 157.618, 157.618, 157.086, 157.086, 157.086, 155.988, 165.232, 165.232, 165.232, 165.232, 165.232, 165.232, 169.269, 169.269, 169.269, 169.269, 169.269, 159.945, 159.945, 159.945, 159.945, 159.945, 162.782, 156.682, 153.997, 153.997, 153.997, 153.997, 153.997, 152.243, 152.243, 152.243, 149.453, 149.453, 149.453, 149.453, 149.453, 152.456, 152.456, 154.502, 154.502, 154.502, 154.502, 154.502, 154.502, 154.502, 154.502, 156.954, 155.211, 155.211, 155.211, 155.211, 155.211, 155.211, 155.211, 155.211, 155.854, 162.399, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 162.041, 159.715, 161.758, 161.758, 161.758, 161.758, 161.758, 161.758, 165.389, 165.389, 165.389, 165.389, 163.499, 163.499, 163.499, 163.499, 161.179, 161.179, 161.641, 161.641, 161.641, 155.937, 155.937, 155.937, 155.937, 155.937, 155.937, 158.526, 161.132, 161.132, 161.132, 161.132, 163.377, 163.377, 164.565, 166.281, 166.281, 166.281, 166.281, 161.838, 161.838, 161.838, 161.838, 161.838, 163.318, 163.318, 163.318, 163.318, 161.111, 161.111, 161.111, 161.111, 161.111, 161.111, 161.111, 161.111, 158.488, 158.488, 158.488, 158.488, 161.214, 161.214, 161.811, 161.811, 161.933, 161.933, 161.933, 161.933, 161.933, 161.933, 161.933, 161.933, 161.933, 164.995, 164.995, 164.995, 164.995, 164.995, 164.995, 164.995, 164.995, 164.995, 164.995, 170.703, 170.703, 170.703, 170.703, 170.703, 169.464, 169.464, 169.464, 169.464, 169.464, 167.275, 167.275, 167.275, 165.546, 168.255, 168.483, 168.483, 168.483, 170.343, 170.343, 170.781, 170.781, 177.172, 177.172, 177.172, 177.172, 177.172, 171.912, 171.912, 171.912, 171.912, 169.246, 169.246, 169.246, 169.231, 169.231, 169.231, 169.231, 169.231, 169.231, 169.229, 169.229, 169.229, 169.229, 169.229, 169.229, 169.229, 169.229, 169.356, 169.356, 169.356, 163.655, 163.655, 160.695, 160.695, 161.912, 161.912, 161.912, 161.912, 161.912, 161.912, 161.912, 161.912, 159.9, 158.036, 158.036, 158.036, 158.036, 158.036, 158.036, 158.036, 158.036, 158.036, 155.747, 155.747, 155.747, 155.747, 155.747, 153.763, 156.032, 156.032, 156.032, 156.389, 158.845, 158.845, 163.776, 163.776, 158.746, 158.746, 158.746, 158.746, 158.746, 158.746, 158.746, 158.746, 150.038, 150.038, 150.038, 150.038, 147.772, 147.772, 147.772, 147.772, 145.405, 145.405, 145.405, 145.405, 145.405, 145.405, 145.405, 147.575, 142.1, 142.1, 142.1, 142.1, 142.1, 139.825, 139.825, 139.825, 142.408, 144.566, 143.24, 143.24, 143.24, 143.24, 143.24, 143.24, 143.24, 143.24, 143.24, 136.769, 136.769, 136.769, 143.529, 143.529, 143.173, 143.173, 143.173, 143.173, 141.366, 141.366, 141.366, 143.535, 142.381, 141.321, 141.321, 141.321, 141.321, 141.321, 141.321, 141.321, 141.608, 141.608, 141.608, 144.487, 144.487, 144.487, 144.487, 144.487, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 144.946, 149.31, 149.31, 149.31, 149.31, 149.31, 149.31, 149.31, 149.31, 149.896, 149.896, 145.263, 145.263, 145.263, 145.263, 151.33, 153.663, 153.663, 153.663, 153.663, 153.663, 153.663, 153.663, 153.663, 153.663, 155.106, 155.106, 155.106, 155.106, 155.106, 152.741, 152.741, 152.741, 152.741, 150.517, 150.517, 150.517, 150.517, 150.517, 150.517, 150.517, 152.732, 152.732, 152.732, 150.721, 150.721, 150.721, 148.283, 148.283, 148.283, 148.283, 148.283, 149.96, 152.117, 152.117, 152.117, 152.117, 152.117, 152.117, 152.117, 150.705, 150.705, 150.705, 150.705, 150.705, 152.022, 155.013, 155.013, 155.013, 155.013, 155.013, 155.013, 155.013, 155.013, 155.013, 155.013, 155.013, 155.013, 155.819, 155.819, 155.819, 155.819, 155.819, 162.118, 162.118, 162.118, 162.118, 162.118, 162.118, 162.118, 162.118, 164.443, 164.443, 164.443, 160.621, 158.735, 158.735, 158.321, 158.321, 161.59, 162.844, 162.844, 162.844, 162.844, 162.844, 162.844, 162.844, 162.844, 162.844, 162.844, 162.844, 163.278, 163.278, 163.278, 164.538, 164.538, 164.538, 164.538, 164.538, 164.538, 164.538, 164.538, 164.538, 163.068, 163.068, 163.068, 167.605, 167.605, 165.3, 165.3, 165.3, 165.3, 163.532, 163.532, 163.532, 163.532, 163.532, 163.532, 163.532, 163.532, 163.532, 163.532, 161.511, 161.511, 161.511, 161.511, 159.563, 158.706, 158.706, 161.683, 161.683, 161.683, 161.683, 161.683, 161.683, 161.683, 161.683, 161.683, 161.683, 161.582, 161.582, 161.582, 161.582, 161.582, 159.435, 159.435, 159.288, 159.288, 159.288, 159.288, 159.288, 159.479, 159.479, 159.479, 161.725, 161.725, 161.725, 161.725, 161.725, 161.725, 161.725, 161.725, 164.161, 162.946, 162.946, 163.385, 163.385, 163.385, 163.385, 163.385, 163.731, 163.731, 163.731, 162.322, 162.322, 162.322, 162.322, 162.322, 163.811, 161.91, 161.91, 156.18, 156.18, 156.18, 152.53, 152.53, 154.581, 154.581, 154.801, 154.801, 154.4, 154.4, 154.4, 154.4, 154.4, 154.4, 154.4, 154.4, 154.4, 154.4, 152.985, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 154.811, 161.983, 161.983, 163.968, 163.968, 166.34, 166.34, 166.34, 167.997, 167.997, 167.997, 167.997, 167.997, 167.997, 167.997, 167.997, 167.997, 162.47, 168.154, 168.154, 168.154, 168.154, 168.154, 167.132, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 167.264, 165.597, 165.597, 165.406, 165.406, 165.406, 165.406, 165.406, 165.406, 167.795, 167.795, 169.829, 169.829, 169.829, 169.829, 169.829, 169.829, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 172.347, 170.677, 166.463, 161.741, 161.741, 161.612, 163.471, 163.471, 163.471, 163.471, 161.398, 161.398, 161.398, 161.681, 161.713, 161.713] [178.875, 178.789, 178.71, 178.878, 178.805, 178.918, 178.967, 178.951, 179.019, 179.17, 179.064, 179.006, 179.12, 179.207, 179.177, 179.181, 179.135, 179.119, 179.172, 178.947, 179.208, 179.18, 179.085, 179.038, 178.908, 178.946, 178.826, 178.81, 178.984, 179.025, 179.022, 179.126, 179.24, 179.306, 179.404, 179.411, 179.681, 179.637, 179.729, 179.622, 179.719, 179.962, 180.18, 180.054, 180.032, 180.003, 179.939, 180.067, 179.988, 180.002, 180.166, 180.211, 180.142, 180.087, 180.227, 180.262, 180.355, 180.425, 180.463, 180.498, 180.587, 180.677, 180.781, 180.784, 180.787, 180.695, 180.64, 180.649, 180.762, 180.789, 180.832, 180.81, 180.815, 180.906, 181.041, 181.233, 181.364, 181.294, 181.085, 180.912, 180.913, 180.987, 181.034, 181.061, 181.158, 180.993, 180.845, 180.86, 180.933, 180.851, 180.729, 180.743, 180.664, 180.785, 180.677, 180.533, 180.472, 180.398, 180.599, 180.709, 180.67, 180.71, 180.823, 181.009, 180.984, 181.093, 181.072, 180.95, 180.975, 180.866, 180.748, 180.746, 180.922, 180.833, 180.638, 180.613, 180.66, 180.602, 180.59, 180.55, 180.54, 180.69, 180.765, 180.651, 180.503, 180.573, 180.707, 180.804, 180.861, 180.861, 180.766, 180.879, 180.972, 180.97, 181.094, 181.094, 181.164, 181.167, 181.424, 181.175, 181.172, 181.088, 181.281, 181.274, 181.153, 181.115, 181.019, 181.114, 181.325, 181.36, 181.385, 181.269, 180.935, 181.236, 181.192, 181.253, 181.201, 181.199, 181.218, 181.227, 181.136, 181.236, 181.211, 181.024, 181.07, 181.078, 181.012, 180.884, 180.788, 180.792, 180.709, 180.645, 180.672, 180.781, 180.734, 180.805, 180.811, 180.853, 180.829, 180.628, 180.567, 180.783, 180.825, 180.936, 181.079, 181.211, 181.152, 181.112, 181.287, 181.278, 181.453, 181.35, 181.352, 181.186, 181.356, 181.267, 181.208, 180.995, 180.768, 180.612, 180.709, 180.939, 181.163, 181.046, 180.987, 180.829, 180.919, 180.891, 180.918, 180.939, 181.029, 181.044, 181.105, 181.094, 181.145, 181.091, 181.045, 180.958, 180.987, 181.026, 181.077, 181.086, 180.871, 180.938, 181.007, 180.988, 180.797, 180.723, 180.943, 180.787, 180.899, 180.852, 180.919, 181.081, 181.054, 181.219, 181.466, 181.542, 181.508, 181.518, 181.483, 181.504, 181.317, 181.17, 181.14, 181.094, 180.913, 181.02, 181.189, 181.03, 181.076, 181.239, 181.079, 181.007, 181.02, 180.981, 180.948, 181.018, 181.034, 181.09, 181.096, 180.94, 180.917, 180.961, 180.761, 180.805, 180.811, 180.924, 180.86, 180.875, 180.982, 181.187, 181.499, 181.424, 181.36, 181.195, 181.148, 181.047, 180.911, 180.739, 180.835, 180.754, 180.646, 180.632, 180.517, 180.304, 180.206, 180.149, 180.054, 180.003, 180.211, 180.348, 180.668, 180.584, 180.737, 180.721, 180.946, 180.934, 181.092, 181.117, 180.828, 180.796, 180.654, 180.574, 180.688, 180.553, 180.554, 180.613, 180.411, 180.426, 180.116, 180.209, 180.176, 180.185, 180.23, 180.367, 180.335, 180.338, 180.294, 180.411, 180.262, 180.173, 180.133, 180.172, 180.374, 180.252, 180.335, 180.364, 180.268, 180.149, 179.988, 179.955, 179.984, 179.992, 180.032, 180.13, 180.249, 180.223, 180.094, 180.063, 180.2, 180.102, 179.789, 179.869, 179.91, 179.841, 179.779, 179.802, 179.744, 179.811, 179.845, 179.769, 179.683, 179.786, 179.814, 179.776, 179.796, 179.59, 179.335, 179.392, 179.546, 179.402, 179.48, 179.421, 179.309, 179.269, 179.618, 179.517, 179.441, 179.413, 179.515, 179.591, 179.561, 179.659, 179.518, 179.568, 179.49, 179.657, 179.611, 179.609, 179.737, 179.861, 179.986, 180.111, 180.067, 180.048, 180.022, 180.034, 180.025, 179.985, 179.976, 180.012, 179.885, 179.84, 179.928, 179.827, 179.891, 179.872, 179.884, 179.7, 179.649, 179.611, 179.828, 179.676, 179.767, 179.771, 179.613, 179.796, 179.881, 179.961, 179.905, 179.919, 179.906, 180.171, 180.188, 180.119, 180.202, 180.127, 180.186, 180.078, 180.231, 180.22, 180.11, 180.047, 180.093, 180.101, 180.243, 180.299, 180.391, 180.23, 180.161, 180.111, 180.11, 180.019, 180.131, 180.201, 180.289, 180.294, 180.329, 180.19, 180.265, 180.196, 180.136, 180.19, 180.121, 179.998, 179.93, 179.927, 179.908, 179.709, 179.721, 179.527, 179.545, 179.599, 179.847, 180.023, 179.861, 179.857, 179.924, 179.855, 179.776, 179.75, 179.747, 179.752, 179.964, 179.993, 180.208, 180.143, 180.087, 180.178, 180.083, 180.16, 180.173, 179.997, 180.121, 180.164, 180.222, 180.159, 180.173, 180.199, 180.394, 180.262, 180.376, 180.436, 180.286, 180.291, 180.45, 180.416, 180.112, 180.12, 180.283, 180.134, 180.186, 180.333, 180.435, 180.593, 180.489, 180.645, 180.854, 180.742, 180.744, 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